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Pet-friendly vacation rentals in Santee

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Santee

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 210 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Top guest favorite
Cottage in Sumter
4.97 out of 5 average rating, 521 reviews

Restful Lakeside Cottage -Dogs allowed

This pond-side cottage is a peaceful place to relax & unwind. Sit in the sunroom and enjoy watching the birds & the water or enjoy the front porch rockers where you can listen to the birds & frogs. We are 12 min. from downtown Sumter & 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens, Poinsett State Park & Congaree Nat. Park. It's only 2 hrs to Myrtle Beach or Charleston & 3 hrs to the mtns. While it's conveniently located, this cottage offers a quiet place to relax.

Top guest favorite
The tranquil bedroom features a spacious bed with floral bedding, accented by a red throw blanket. A wooden bedside table holds a woven basket. Natural light enters through sliding doors, leading to a small private deck surrounded by trees.
Cottage in Summerville
4.92 out of 5 average rating, 257 reviews

KING, 4 beds, 5 minutes to I-26

This quiet Cottage is an easy 5 minutes to I-26. Bedroom #1 - KING Bedroom #2 - (2) TWINS Space #3 - QUEEN Cozy and private sleeping space converted from a large storage area. Wi-Fi is strong and fast. Televisions in every room. Helpful items for babies and children. Kitchen has full-size appliances and is fully stocked. Ice cold air conditioning, warm heat, and steaming hot water - all new! Bedrooms/bath are on the 2nd floor, using gently sloped stairs. Larger vehicles are welcome.

Guest favorite
A charming single-story brick home is shown with a welcoming entrance featuring a circular window and black door. The front yard is landscaped with grass and bushes, while large trees provide shade in the background. A concrete pathway leads to the front steps.
Home in Sumter
4.89 out of 5 average rating, 234 reviews

Bungalow on Bobs

This charming 3 bedroom, 2 bathroom brick home features an updated kitchen with granite countertops and stainless steel appliances. The great backyard space is fully-fenced, with a large deck, charcoal grill, and fire pit. The spacious master bedroom has a private bathroom and a large walk-in closet. The master bedroom and living room both have Smart TVs. Log in to your own streaming accounts, or enjoy the complimentary Hulu account. The split floor plan allows for easy separation of guests.

Guest favorite
Condo in Santee
4.81 out of 5 average rating, 21 reviews

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

Recently Remodeled! Private corner unit with panoramic lake views! - Amenities: pool, fishing pier, boat ramp, grill area, boardwalk, walking/biking bridge, parking, wifi - Santee Ntnl Golf Club 6min - Santee Cooper Cntry Club 12min - Lake Marion Golf Club 7min - Santee State Park 9min - Santee Ntnl Wildlife Refuge 24min Smart TVs in bedrooms and living area 2 Dogs allowed - must be included in reservation Only registered guests and pets on site Absolutely no smoking/vaping of any kind

Top guest favorite
A charming log home is set on a grassy lot, surrounded by trees. The faƧade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 255 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Guest favorite
Cabin in Saint Matthews
4.78 out of 5 average rating, 193 reviews

A relaxing cabin on private pond. Old Bells Secret

Escape to our secluded cabin on 90 acres in St. Matthews, SC! This early 2000s style cabin features 2 cozy bedrooms, 1 bathroom, and a lovely porch. The large pond is perfect for swimming, fishing, or playing. It’s an endless adventure. The house can sleep up to 6 with the pull out couch. Accessible via a private road, it's perfect for weekend getaways with the family or housing for workers. Experience relaxation and adventure in nature at this wonderful cabin. Book now for a memorable stay!

Top guest favorite
A spacious covered deck provides views of the lake through large trees, featuring two striped chaise loungers and a dining table with four chairs. The wooden flooring enhances the outdoor space, inviting relaxation and enjoyment of the serene surroundings.
Guest suite in Eutawville
4.81 out of 5 average rating, 103 reviews

Relaxing Comfortable Waterfront Family Dock Suite

Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Guest favorite
The cabin exterior is shown, featuring a wrap-around deck with sturdy railings. Large windows allow for ample natural light. The building sits on a grassy area with clear blue skies above, providing a sense of space and serenity.
Tiny home in Sumter County
4.95 out of 5 average rating, 199 reviews

The Cabin at Minehill

Our cabin is located in Stateburg, SC between Columbia and Sumter and within a 5-15 minute commute to Shaw AFB and Sumter. It is a convenient stop between I-77 and I-95 and has close proximity to Poinsett and Congaree Parks and The Palmetto Trail. It sits on top of a hill offering panoramic views, quiet, and privacy. Mine Hill sunrises and sunsets are stunning. Reserve as a stopover, a retreat from the workday, or a romantic getaway and enjoy our cabin as a home away from home.

Guest favorite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.96 out of 5 average rating, 187 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Guest favorite
Home in Summerton
4.93 out of 5 average rating, 29 reviews

Nanny’s Lake Retreat

3 BR, 2 BA. Located in a quiet, dead end community. Enjoy the lake sounds from the spacious screened in porch. The porch has a swing, rocking chairs, and table with chairs. The den boasts a beautiful gas log fireplace and has two futons and a loveseat. The house is located in a golf cart community on a cove. Sandy beaches are just minutes away depending on the lake levels. Whether you’re looking for a vacation destination or fishing/hunting trip you will love this home.

Top guest favorite
A field of blooming yellow flowers is displayed in the foreground, with delicate petals and green stems. In the background, a white farmhouse is visible, providing a serene country setting. The scene captures the tranquility of the flower field adjacent to the cottage.
Tiny home in Moncks Corner
4.95 out of 5 average rating, 160 reviews

The Goose Cottage at Wild Goose Flower Farm

Located next to the family farmhouse at Wild Goose Flower Farm, The Goose Cottage was designed to immerse guests in our calm and peaceful country life. We are located 15 minutes from the hearts of Cane Bay, Nexton and Exit 194 on I-26, and 45 minutes from Downtown Charleston. Two can sleep in the queen size bed but the sofa also extends into a queen-sized sleeper. Please reach out with further questions or if you would like to inquire about an extended stay.

Popular amenities for Santee pet-friendly home rentals

  1. Airbnb
  2. United States
  3. South Carolina
  4. Orangeburg County
  5. Santee
  6. Pet-friendly rentals