Vacation rentals in Orangeburg County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Orangeburg County

Guests agree: these stays are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
Guest favorite
The bedroom features a spacious bed dressed in white linens with red accents. A desk with dual monitors is positioned next to the bed. A dresser and a soft area rug add warmth, while natural light filters in through a window with light drapes.
Home in Orangeburg
4.92 out of 5 average rating, 39 reviews

Theo's Place

Kick back and relax in this calm, stylish space. I'm happy to offer my 1st home as a host, providing all the amenities I've wanted as a guest in my years of successful stays on the AirBnB platform as a guest (laptop not included). My guest will find various comforts and additions to make their stay as comfortable as can be. I welcome your feedback. My home is available as a 1 Bedroom with a large Den, Living & Dining rooms, 2 Bathrooms, full Kitchen and Laundry room. All new appliances as well.

Guest favorite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 182 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Guest favorite
A single-story brick ranch home is set in a green, well-maintained yard. A large palm tree is situated near the entry, with a few steps leading up to the front door. The front porch features two rocking chairs, enhancing the welcoming appearance of the home.
Home in Orangeburg
5 out of 5 average rating, 65 reviews

Trendy, cozy and casual

Total Renovation of 1235 square feet brick ranch with 1 car garage, screened in back porch and large fenced back yard. 2 baths, updated fully equipped kitchen, dishwasher, new floors, curtains & linens. Roku TV, wireless internet. Washer and Dryer Pet Notes: Pets have to be approved in advance of stay and pet fees will be charged per pet. Pets are welcome but there is a pet fee based on number of dogs and breed. Some breed are restricted by insurance company. Contact me before booking please.

Guest favorite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.89 out of 5 average rating, 209 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Top guest favorite
A spacious living area features a large blue sectional sofa adorned with patterned cushions. A light wooden coffee table sits on a soft area rug, complemented by a small potted plant. Natural light filters through the windows, creating a bright and welcoming environment.
Home in Orangeburg
5 out of 5 average rating, 135 reviews

The Grand Marshall

Bring the whole family to this renovated 3 BR, 2 bath home +1 BONUS ROOM, which serves as a theatre/game room with 2 queen sleeper sofas. Your family will enjoy: Coffee/beverage/snack bar Central location: Approximately 5 minutes to SC State and Claflin University, OC Tech College, Edisto Gardens, MUSC Health Orangeburg, shopping, dining, and more. Designated office space 1 king bed, 2 queen beds, plus 2 queen sleeper sofas 5 Roku Smart TV’s Smart lock for easy access High speed WiFi

Guest favorite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.97 out of 5 average rating, 150 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Top guest favorite
A spacious deck overlooks a serene cove, featuring a dining table surrounded by six chairs. Lounge seating is positioned nearby, inviting relaxation. Lush trees frame the area, with views of water and nearby boats visible, creating a calm retreat.
Home in Summerton
4.99 out of 5 average rating, 121 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Top guest favorite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Apartment in Orangeburg
4.99 out of 5 average rating, 141 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Guest favorite
A charming one-story house features a welcoming front porch with two black doors framed by flower pots. An American flag hangs above, and steps lead to the entrance. Greenery surrounds the porch, complemented by a stone pathway and a well-maintained yard.
Bungalow in Blackville
5 out of 5 average rating, 24 reviews

Clover Cottage

Clover Cottage is a cozy place to stay if you need a quiet place to unwind. Located on Main Street, Clover Cottage is walking distance to restaurants and grocery store. The cottage is a completely renovated property which started life as the summer kitchen for the main house. The cottage is 150 years old and has maintained the charm of a historic home. To retain the history of the property and town, NO SMOKING or VAPING is allowed on the property.

Top guest favorite
An aerial view captures a spacious home surrounded by greenery, featuring a turquoise pool in the foreground. Relaxing lounge chairs line the poolside, while colorful plants add vibrancy against the evening sky transitioning into warm hues.
Vacation home in Summerton
4.96 out of 5 average rating, 114 reviews

Lakefront Paradise W/Pool/hot tub/outdoor kitchen

Brand new heated saltwater pool, hot tub and outdoor kitchen area. This upgraded home is ready to host your family or large group! Enjoy breathtaking sunsets year round from your private beach directly on the big waters of Lake Marion. Spends evenings out on the dock fishing or pull your boat right up to the beach. Ping pong and bumper pool tables, fast wifi and big screen tv's make for the perfect entertaining space for large groups.

Top guest favorite
A spacious bed is dressed with a light patterned duvet and decorative pillows. A black nightstand is positioned beside the bed, topped with a textured lamp and a small potted plant. The backdrop features green wainscoting, adding a calming touch to the room.
Apartment in Barnwell
4.99 out of 5 average rating, 119 reviews

Ellzey Place

Ellzey Place is a peaceful spot where you can relax and unwind. Enjoy having a cup of coffee on the deck facing a spacious private back yard. There are lots of azaleas that bloom in season and pines swaying in the breeze. It is a charming apartment attached to the owner's house but has a private deck and entrance. It has been newly remodeled and delightfully decorated.

Superhost
A quaint cottage is nestled among trees, showcasing a wooden façade and a sloped roof. A hammock rests on the side, inviting relaxation. Rocking chairs are placed on the porch, while a white door leads into the interior. Natural light filters through the greenery.
Tiny home in Blackville
4.9 out of 5 average rating, 153 reviews

Spanish Moss (Carolina Cottage)

Enjoy the sounds of nature when you stay in this unique place. Wildlife, Magnolia’s, trees, Spanish Moss draped 200 year old Oak trees, Pecan Orchard Views. Private gated drive to cottage. The Bungalow at Magnolia is located on the same property which does not allow pets 120 feet distance wooded unable to see cottages from each other. 420 friendly property.

Popular amenities for Orangeburg County vacation rentals