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Apartment vacation rentals in Santee

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santee

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Superhost
A wooden dock extends over the tranquil waters, framed by trees with golden leaves. Boats are visible at the floating slips, surrounded by lush greenery and a peaceful lake setting.
Apartment in Santee
4.79 out of 5 average rating, 28 reviews

Dockside Villa Lake Marion

Dockside Villa on lake Marion includes a boat slip just out the back door of condo. 1 king, 1 Queen: 2 private beds and 2 baths plus pull out sofa bed in living room. Condo is fully furnished which means it will sleep up to six comfortably for a family/friends, golfing-lake adventure. Bring your boat - keep it at the dock during your stay or rent a boat next door. The amenity package includes outdoor grills, walking trails, and a boat landing. 3 world class golf courses are 3 to 5 minutes away.

Guest favorite
The exterior of a single-story, light-colored home is shown, featuring a sloped roof and front steps leading to a welcoming entryway. Lush greenery, including shrubs and trees, surrounds the house, creating a serene environment. A covered porch is visible, enhancing the outdoor space.
Apartment in Orangeburg
4.83 out of 5 average rating, 29 reviews

Cozy and Charming on Raysor

Cozy and comfortable fully furnished one bedroom on quiet street, fenced back yard and off street parking. Living room, Dining room, Office, Modern Kitchen, huge deck table, chairs. WiFi, Internet, TVs, Washer & Dryer. Pet Notes: Pets have to be approved in advance of stay and pet fees will be charged Pets are welcome but there is a pet fee based on number of dogs and breed. Airbnb only charged for 1 pet, we send request for additional pet fees. Some breed are restricted by insurance company.

Top guest favorite
Apartment in Summerville
4.96 out of 5 average rating, 46 reviews

*Azalea Bar•Secret Garden Apt - sleeps 3

Stay in the Heart of Downtown Summerville! Perched above The Azalea, a sophisticated cocktail bar, this historic suite offers the ultimate downtown location and comfort that cannot be beat! Blending modern amenities with southern charm, it’s perfect for those who love being in the center of it all. Step outside & explore all that Flowertown has to offer-eclectic shops & fantastic restaurants or, take a short trip to Charleston & or our fantastic beaches. Book your unforgettable stay today!

Superhost
A comfortable living area features a gray sofa and matching loveseat, accented with yellow pillows. A gold coffee table sits atop a patterned area rug, while natural light fills the space through two sets of glass doors leading to a private porch.
Apartment in Ladson
4.83 out of 5 average rating, 41 reviews

King Bed-Pool-24/7 Gym-Kitchen

Just listed 1BR 1BA Top Floor Corner Apartment King Bed Pool and 24/7 Gym access included. We are in immediate proximity of Boeing, Mercedes Benz, Cummins Turbo, Daimler AG, Volvo and other top employers in the area. 5 mins to Charleston Southern and Trident Medical Center 5 mins to I-26 17 mins to airport 20 mins into downtown Don't see availability for your dates? Send an inquiry to my co-hosts and I. We manage other rentals in the area and are happy to answer any and all questions.

Guest favorite
A comfortable seating area features a white sofa and two green chairs, arranged around a glass coffee table. Soft light from a nearby floor lamp enhances the inviting space, while double doors with blinds provide access to the outdoor area.
Apartment in Ladson
4.85 out of 5 average rating, 48 reviews

2BR 2BA - Pool & Gym - Mins to I-26, Mercedes, CSU

2BR 2BA 3rd Floor Apartment located in remodeled apartment complex with amenities: Pool Gym open 24/7 Gas Grills Conveniently located to I-26 ( 3 mins), Mercedes (7 mins.), Charleston Southern Univ. (5 mins.), Trident Hospital (5 mins.), Volvo, and more! 15 mins. to airport, 23 mins. to Downtown Charleston, 30 mins. to Sullivans Island. Need more rooms? We manage 10 other apartments at this complex and 95 other properties in the Charleston area. Please reach out with any questions!

Top guest favorite
Apartment in Moncks Corner
5 out of 5 average rating, 38 reviews

Cozy escape studio apartment

Welcome to your perfect little retreat! This cozy studio apartment is nestled in the vibrant heart of our charming small town, just steps away from local shops, cafes, parks, and everything you need for a comfortable visit (See guidebook). We are minutes from several boat ramps on the lake and river listed in the guidebook. We have plenty of space in our driveway for you to bring your boat! 🚤 This is also a perfect extended stay space for traveling nurses and respiratory therapists! 🩺

Guest favorite
A private entrance to the guest quarters is framed by lush greenery and potted plants. The entrance features double doors with multiple panes, leading into a welcoming atmosphere. A small welcome mat is positioned at the door, complemented by a light-colored chair nearby.
Apartment in Summerville
4.82 out of 5 average rating, 11 reviews

Private Guest Quarters at Linwood - 1 bed/1 bath

The Private Guest Quarters at Linwood is a cozy 1 bed/1 bath apartment located beneath the main house at Linwood, Historic Home and Gardens, a 2-acre Victorian era estate built in 1883. The apartment has its own private entrance and is equipped with a small kitchen, a dining area, one bedroom, one bathroom and a washer/dryer. Amenities include Cable TV, free Wi-Fi, bed linens, bath towels and off street parking. A unique, comfortable and private living experience for one or two guests!

Superhost
A stylish living area features a green velvet sofa paired with two accent chairs and a round coffee table. A rug adds warmth to the carpeted floor. The space is illuminated by natural light from a window, while a tall plant provides a refreshing touch.
Apartment in Ladson
4.85 out of 5 average rating, 46 reviews

King Bed-Pool and Gym-Kitchen

Enjoy a stylish experience at this centrally-located place! 1BR 1BA Apartment with King Bed. Pool and 24/7 Gym access included. We are in immediate proximity of Boeing, Mercedes Benz, Cummins Turbo, Volvo and other top employers in the area. 5 mins to Charleston Southern and Trident Medical Center 5 mins to I-26 17 mins to airport 20 mins into downtown Don't see availability for your dates? Send us an inquiry. We manage other rentals in the area. Happy to help!

Top guest favorite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Apartment in Orangeburg
4.99 out of 5 average rating, 171 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Guest favorite
A comfortable seating area is highlighted by a light grey sofa adorned with a patterned throw. Two vintage chairs frame a small coffee table, which is topped with books. Natural light filters through an arched window with a softly shaded blind.
Apartment in Elloree
4.86 out of 5 average rating, 22 reviews

Modern apartment overlooking a Historic Downtown

Relax at this peaceful and centrally-located getaway in the heart of historic Elloree, SC. Just minutes away from Santee, I95, I26, fishing and golfing, it's perfect for a quiet weekend getaway, business trip or staycation! Free electric car charging available for your convenience upon request.

Superhost
A comfortable living area features a light-colored sofa and two green armchairs. A coffee table sits on a patterned rug, and a television is positioned on a wooden stand. Light streams through the double doors, which lead to a balcony.
Apartment in Ladson
4.79 out of 5 average rating, 38 reviews

2BR 2BA - Pool & Gym - Mins to I-26, Mercedes, CSU

Just Listed 2BR 2BA Apartment. Unit includes access to pool and gym, as well as other amenities on-site. Near Boeing, Mercedes Benz, Cummins Turbo , Daimler AG, Volvo 5 mins to Charleston Southern + Trident Medical Center 5 mins to I-26 17 mins to airport 20 mins into downtown

Top guest favorite
The sitting area features a dark gray sectional sofa positioned next to a low coffee table. A mounted flat-screen TV is visible on the wall. Bright natural light enters through two large windows, illuminating the plush carpeted floor.
Apartment in Moncks Corner
4.88 out of 5 average rating, 178 reviews

Jay’s Upstairs Suite

Central to Moncks Corner, Goose Creek and Summerville. Suite is upstairs and is closed off from the rest of the house. Private back door entrance. Discounts for long term stays.

Popular amenities for Santee apartment rentals

Quick stats about apartment rentals in Santee

  • Total vacation rentals

    Explore 10 vacation rentals in Santee

  • Nightly prices starting at

    Santee vacation rentals start at G$31,375 GYD per night before taxes and fees

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Santee vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santee rentals