Apartment vacation rentals in Santee

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Top-rated apartment rentals in Santee

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Guest favorite
A wooden dock extends over the tranquil waters, framed by trees with golden leaves. Boats are visible at the floating slips, surrounded by lush greenery and a peaceful lake setting.
Apartment in Santee
4.84 out of 5 average rating, 25 reviews

Dockside Villa Lake Marion

Dockside Villa on lake Marion includes a boat slip just out the back door of condo. 1 king, 1 Queen: 2 private beds and 2 baths plus pull out sofa bed in living room. Condo is fully furnished which means it will sleep up to six comfortably for a family/friends, golfing-lake adventure. Bring your boat - keep it at the dock during your stay or rent a boat next door. The amenity package includes outdoor grills, walking trails, and a boat landing. 3 world class golf courses are 3 to 5 minutes away.

Top guest favorite
Apartment in Moncks Corner
5 out of 5 average rating, 36 reviews

Cozy escape studio apartment

Welcome to your perfect little retreat! This cozy studio apartment is nestled in the vibrant heart of our charming small town, just steps away from local shops, cafes, parks, and everything you need for a comfortable visit (See guidebook). We are minutes from several boat ramps on the lake and river listed in the guidebook. We have plenty of space in our driveway for you to bring your boat! 🚤 This is also a perfect extended stay space for traveling nurses and respiratory therapists! 🩺

Top guest favorite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Apartment in Orangeburg
4.99 out of 5 average rating, 160 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Guest favorite
A serene lakeside view is captured at sunset, displaying a colorful sky with hues of orange, pink, and blue. The calm water reflects the clouds, adding to the tranquil atmosphere. A wooden dock extends into the lake, enhancing the peaceful setting.
Apartment in Moncks Corner
4.81 out of 5 average rating, 16 reviews

Ophir Oasis Unit #3

Stylish, clean, and Simplistic Studio Apartment at Locklairs Landing. Unit 3 offers a perfect blend of comfort and simplicity. This studio, 1-bath is ideal for relaxing or working remotely. As well as a kitchen area fully equipped with apartment sized appliances. The property is perfect for swimming, fishing, or taking in the scenery. If you're seeking a quiet getaway or active retreat, our apartment at Locklairs Landing offers a lakeside oasis.

Superhost
A serene lakeside view is presented, featuring multiple building levels illuminated softly by exterior lights. A wooden dock extends towards the water, surrounded by lush greenery and trees, creating a peaceful atmosphere along the shoreline.
Apartment in Santee

3-Bedroom Dlx @ Lake Marion Resort

You'll have a great time at this comfortable place to stay. When a trip calls for water and the ocean won’t do, a lake retreat is just the thing. Escape the everyday at this peaceful retreat located on Lake Marion’s Chapel Branch. Explore South Carolina’s largest lake, or discover other adventures like horseback riding, mountain biking, or hiking. And if the greens are more your thing, the area is brimming with exceptional golf courses, too.

Superhost
The image displays a multi-story building with large windows, surrounded by autumn trees featuring vibrant orange leaves. A dock is visible in front, with a red kayak resting on the water, reflecting the calming lake environment.
Apartment in Santee

Lake Marion Resort 1 Bedroom Unit

Take a break and unwind at this peaceful oasis. When a trip calls for water and the ocean won’t do, a lake retreat is just the thing. Escape the everyday at this peaceful retreat located on Lake Marion’s Chapel Branch. Explore South Carolina’s largest lake, or discover other adventures like horseback riding, mountain biking, or hiking. And if the greens are more your thing, the area is brimming with exceptional golf courses, too.

Superhost
An outdoor balcony features a dining table surrounded by four mesh chairs. A ceiling fan is visible above, and the view includes a serene lake framed by trees under a clear blue sky.
Apartment in Santee
4.85 out of 5 average rating, 34 reviews

Relaxation is the plan

Come and relax in this peaceful retreat. A beautiful view of the lake and the sunset from the comfort of the living area or outside on the spacious balcony, a stunning lakefront property offering breathtaking views. This meticulously maintained 2-bedroom, 2-bathroom condo is centrally located off I-95, providing both privacy and convenience. The serene lake views and well-kept interiors create a peaceful retreat for relaxation.

Superhost
A serene lake view is captured from a wooden dock, with a small boat moored at the edge. Vibrant autumn foliage reflects on the calm water, creating a colorful and tranquil atmosphere. The sky features soft clouds and hints of blue, complementing the surrounding nature.
Apartment in Santee

Lakeside Bliss 2BR/2BA Suite Wyndham Lake Marion

Escape to lakeside bliss at our spacious 2-bedroom, 2-bathroom resort suite located in the serene Wyndham Lake Marion. Embrace the tranquility of the picturesque surroundings as you unwind in this comfortable retreat. Book your stay at our lakeside 2BR suite and experience the perfect blend of relaxation and adventure at Wyndham Lake Marion. Create unforgettable memories in this scenic oasis.

A cozy living area is highlighted by a brown sofa, a wooden coffee table, and a small dining table. The kitchen features light cabinets and stainless steel appliances. A ceiling fan is visible above, and a television is positioned on a stand against the wall.
Apartment in Summerton
4.75 out of 5 average rating, 8 reviews

Come on Down to Goat Island!

Come relax by the lake with your family or friends at this peaceful place to stay. This remodeled 1 bedroom 1 bath condo located on the beautiful Goat Island in Summerton, SC (right on Lake Marion). This quant condo features a full kitchen, living room and the upstairs bathroom and bedroom with a balcony. Boat slip rental available.

A serene view captures a community pool bordered by lush greenery and palm trees. The lake reflects a pastel sunset, enhancing the tranquil atmosphere. Chairs are arranged around the pool, inviting relaxation. A well-maintained pathway leads through the landscape towards the water's edge.
Apartment in Santee
4.83 out of 5 average rating, 6 reviews

Lake and pool side vacationing

Bring the whole family to this great place with lots of room for fun. community pool just a few steps away and the biggest lake in SC right behind it and a sandy cove a couple hundred feet way. Bring or rent a boat and use the private boat landing and a dock to tie off. Condo is probably the nicest in the building!

Guest favorite
A comfortable seating area is highlighted by a light grey sofa adorned with a patterned throw. Two vintage chairs frame a small coffee table, which is topped with books. Natural light filters through an arched window with a softly shaded blind.
Apartment in Elloree
4.9 out of 5 average rating, 20 reviews

Modern apartment overlooking a Historic Downtown

Relax at this peaceful and centrally-located getaway in the heart of historic Elloree, SC. Just minutes away from Santee, I95, I26, fishing and golfing, it's perfect for a quiet weekend getaway, business trip or staycation! Free electric car charging available for your convenience upon request.

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Apartment in Orangeburg
New place to stay

Second Home Apartment

Enjoy your stay at Second Home Apartment, a warm and inviting home in a great location. Conveniently close to everything you need, it’s perfect for a comfortable and relaxing stay.

Popular amenities for Santee apartment rentals

Quick stats about apartment rentals in Santee

  • Total vacation rentals

    Explore 10 vacation rentals in Santee

  • Nightly prices starting at

    Santee vacation rentals start at G$31,383 GYD per night before taxes and fees

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Vacation rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    10 of Santee vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santee rentals