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Pet-friendly vacation rentals in Orangeburg County

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Orangeburg County

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Orangeburg
4.94 out of 5 average rating, 35 reviews

Cozy, comfy, convenient, cottage!

We think you'll love this peaceful, family friendly cottage. For a price similar to a local hotel, you'll get a newly remodeled 2-bedroom house complete with kitchen and formal dining room located on fenced in lot 🐶 in quiet neighborhood. The master has a king bed with 400 count Egyptian cotton sheets and a bamboo mattress topper. The guest has a queen bed with a sensafoam mattress. There is a new 50” tv and high speed fiber WI-FI. There is also a breakfast bar with your favorite coffee.

Superhost
A cozy bedroom is featured with a spacious bed adorned in a patterned quilt and colorful pillows. Two windows are dressed with light green curtains, allowing natural light to enter. A lamp and a decorative vase enhance the calming ambiance, while a wooden dresser adds functionality.
Home in Orangeburg
4.86 out of 5 average rating, 36 reviews

Nene's Cozy Corner

Time to get Cozy. Relax here with your family and friends at this peaceful place to stay. Or stay if in the area for work. Close to Edisto Memorial Gardens, 8 miles to South Carolina State University, 9 miles to Claflin University, a couple of minutes away from the drag strip, 11.5 miles from The Hillcrest Golf Club and close to many restaurants, stores and shopping centers. Come kickback and relax at “Nene’s Cozy Corner”. Extra parking in front and back yard for motorbikes, boats, cars and more

Guest favorite
A charming waterfront home is surrounded by trees, featuring a screened porch that provides a view of the yard. Green grass on a gentle slope leads up to the house, with bushes adding a touch of greenery. A dog stands near the porch, complementing the serene setting.
Home in Cameron
4.85 out of 5 average rating, 20 reviews

Fisherman's Dream at Low Falls Landing-Lake Marion

Don't Overlook this Waterfront Property! Fisherman's Dream on Lake Marion and Duck Hunter's Delight! Throw back from the 70's! Put in at Low Falls Landing & then tie on to the property's private dock. This is a 2 bdrm, 2 bth home. Screened porch w/swing & rocking chairs over looks waterfront. Open family rm & kitch. Gather w/friends & family. Large private dock w/ seating and rod holders. Lake Marion, largest lake in SC, catfish, crappy and brim fishing. Dogs welcome, No cats please.

Top guest favorite
The rustic cabin features weathered wooden siding and a metal roof partially covered by overhanging branches. A front porch with railings leads to a small entry door, surrounded by grass and shrubs. The serene natural setting complements the cabin's quaint charm.
Cabin in Rowesville
4.95 out of 5 average rating, 205 reviews

Mulberry Cabin, a rustic tiny house cabin

Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Guest favorite
A serene lakeside view captures a wooden dock extending into calm waters, surrounded by trees. Buildings are visible in the background, subtly illuminated by dusk light. The sky displays gentle hues of blue and pink, reflecting the tranquil atmosphere of the location.
Home in Vance
4.95 out of 5 average rating, 20 reviews

Lakefront w/ dock at Mill Creek

Nestled between Santee & Eutawville, Vance is less than an hour from Downtown Charleston. Experience lake life w/ a front row seat to live music, dancing & karaoke at the Mill Creek Marina! Float over to grab a bite or drink at the Barefoot Lakeside Bar & Mill Creek Food & Spirits! Community hosts golf cart parades, Halloween bash, & a spectacular 4th of July fireworks show. Launch your pontoon a few doors down, tie up at your dock & conveniently fuel up at the marina. Campground store on site!

Guest favorite
Farm stay in Eutawville
4.89 out of 5 average rating, 9 reviews

Welcome to The Days End-Farmstay w/ Animals

Welcome to The Days End! Where modern comfort meets country charm 🌾 This home is for quiet stays only — no parties or events are allowed. A thoughtfully designed 700 sq ft farm cabin retreat tucked away on 11 acres of peaceful pastures. Located less than 45 minutes from downtown Summerville, 40 minutes from I-20, 1 hr from Downtown Charleston, and 25 minutes from I-95. We are a livestock property and for the safety of our animals we only allow 1 pet per reservation with a strict leash policy.

Guest favorite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 238 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Top guest favorite
A spacious lakefront home is visible from the water, surrounded by lush green trees. The two-story structure features porches on each level. A sandy beach area and grassy yard lead up to the house, with white lounge chairs placed nearby, inviting relaxation by the water.
Home in Summerton
4.96 out of 5 average rating, 48 reviews

Large Lakefront Home w/360 view, beaches, & dock

This family-friendly spacious lakefront home with dock is located on a peninsula and boasts water access on three sides of the property. Park your boat at your own personal dock using the boat ramp located directly across from the property. This property has room for 13 people, but there is also access to an air mattress. Enjoy the 3 huge porches, fire pit, paddle boat, hammocks and swings, fishing, drop in your kayak or paddle board straight off the property and head out to Lake Marion.

Top guest favorite
A spacious covered deck provides views of the lake through large trees, featuring two striped chaise loungers and a dining table with four chairs. The wooden flooring enhances the outdoor space, inviting relaxation and enjoyment of the serene surroundings.
Guest suite in Eutawville
4.8 out of 5 average rating, 102 reviews

Relaxing Comfortable Waterfront Family Dock Suite

Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Guest favorite
Home in Summerton
4.94 out of 5 average rating, 171 reviews

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Guest favorite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.97 out of 5 average rating, 176 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Guest favorite
A charming exterior view of a single-story home features a welcoming front porch with white railing. The entrance is flanked by neatly trimmed hedges and a gently sloping yard, while large windows allow for natural light to fill the interior.
Home in Orangeburg
4.97 out of 5 average rating, 31 reviews

Columbia Road Escape

Great in town location, recently renovated kitchen and bath, Luxury Vinyl Plank floors, and nicely appointed with dedicated workspace, off street parking, convenient to shopping and restaurants. We host Travelers for the local hospital and other medical facilities. Pet Notes: Pets are to be approved in advance, Pets are welcome but there is a pet fee based on number of dogs and breed. Some breed are restricted by insurance company. Contact me before booking please.

Popular amenities for Orangeburg County pet-friendly home rentals