
Pet-friendly vacation rentals in Orangeburg County
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Orangeburg County
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Cozy, comfy, convenient, cottage!
We think you'll love this peaceful, family friendly cottage. For a price similar to a local hotel, you'll get a newly remodeled 2-bedroom house complete with kitchen and formal dining room located on fenced in lot 🐶 in quiet neighborhood. The master has a king bed with 400 count Egyptian cotton sheets and a bamboo mattress topper. The guest has a queen bed with a sensafoam mattress. There is a new 50” tv and high speed fiber WI-FI. There is also a breakfast bar with your favorite coffee.

Nene's Cozy Corner
Time to get Cozy. Relax here with your family and friends at this peaceful place to stay. Or stay if in the area for work. Close to Edisto Memorial Gardens, 8 miles to South Carolina State University, 9 miles to Claflin University, a couple of minutes away from the drag strip, 11.5 miles from The Hillcrest Golf Club and close to many restaurants, stores and shopping centers. Come kickback and relax at “Nene’s Cozy Corner”. Extra parking in front and back yard for motorbikes, boats, cars and more

Fisherman's Dream at Low Falls Landing-Lake Marion
Don't Overlook this Waterfront Property! Fisherman's Dream on Lake Marion and Duck Hunter's Delight! Throw back from the 70's! Put in at Low Falls Landing & then tie on to the property's private dock. This is a 2 bdrm, 2 bth home. Screened porch w/swing & rocking chairs over looks waterfront. Open family rm & kitch. Gather w/friends & family. Large private dock w/ seating and rod holders. Lake Marion, largest lake in SC, catfish, crappy and brim fishing. Dogs welcome, No cats please.

Mulberry Cabin, a rustic tiny house cabin
Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Lakefront w/ dock at Mill Creek
Nestled between Santee & Eutawville, Vance is less than an hour from Downtown Charleston. Experience lake life w/ a front row seat to live music, dancing & karaoke at the Mill Creek Marina! Float over to grab a bite or drink at the Barefoot Lakeside Bar & Mill Creek Food & Spirits! Community hosts golf cart parades, Halloween bash, & a spectacular 4th of July fireworks show. Launch your pontoon a few doors down, tie up at your dock & conveniently fuel up at the marina. Campground store on site!

Welcome to The Days End-Farmstay w/ Animals
Welcome to The Days End! Where modern comfort meets country charm 🌾 This home is for quiet stays only — no parties or events are allowed. A thoughtfully designed 700 sq ft farm cabin retreat tucked away on 11 acres of peaceful pastures. Located less than 45 minutes from downtown Summerville, 40 minutes from I-20, 1 hr from Downtown Charleston, and 25 minutes from I-95. We are a livestock property and for the safety of our animals we only allow 1 pet per reservation with a strict leash policy.

Log home on Lake Marion inlet w/private dock.
Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Large Lakefront Home w/360 view, beaches, & dock
This family-friendly spacious lakefront home with dock is located on a peninsula and boasts water access on three sides of the property. Park your boat at your own personal dock using the boat ramp located directly across from the property. This property has room for 13 people, but there is also access to an air mattress. Enjoy the 3 huge porches, fire pit, paddle boat, hammocks and swings, fishing, drop in your kayak or paddle board straight off the property and head out to Lake Marion.

Relaxing Comfortable Waterfront Family Dock Suite
Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Luxurious Lakefront Log Home W/Pool & hot tub
Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Pet-Friendly Lake Marion Getaway - Just off I-95!
In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Columbia Road Escape
Great in town location, recently renovated kitchen and bath, Luxury Vinyl Plank floors, and nicely appointed with dedicated workspace, off street parking, convenient to shopping and restaurants. We host Travelers for the local hospital and other medical facilities. Pet Notes: Pets are to be approved in advance, Pets are welcome but there is a pet fee based on number of dogs and breed. Some breed are restricted by insurance company. Contact me before booking please.
Popular amenities for Orangeburg County pet-friendly home rentals
Pet-friendly house rentals

Rest and Relaxation

Santee/Lizzie's Creek Lakefront

Lakefront home with boat ramp and game room

The Cypress House

Almost Heaven on Lake Marion, SC

Lake Marion Cottage

Blue Bungalow

Stanley's Lake House
Pet-friendly home rentals with a pool

LuxuryGrndFloorCornerLakeViewPoolGolfFishBoatParks

Lakefront Lookout

Enjoy Your Day On the Lake! Direct Access w/Dock

Lakefront Farmhouse Retreat+Pool

Renovated Retreat w/ Private Pool & Hot Tub

Lake Marion - Majestic Big Water Views
Private, pet-friendly home rentals

Annie's Place (A great day at Lake Marion!)

7 Minutes from 95! Campsite III

Peaceful Tiny Home Getaway

The Heron Lake House

Glamping on Brown Shuga and Spice Acres

Cypress Creek Lodge

Quiet Family-Friendly Farm Stay • Sleeps 8

Lakeside via Mars Bluff
Destinations to explore
- Rentals with a patio Orangeburg County
- Rentals with a hot tub Orangeburg County
- Rentals with lake access Orangeburg County
- Hotel rooms Orangeburg County
- Rentals with outdoor seating Orangeburg County
- Condo rentals Orangeburg County
- Rentals with pools Orangeburg County
- Rentals with a fireplace Orangeburg County
- House rentals Orangeburg County
- Rentals with a fire pit Orangeburg County
- Family-friendly rentals Orangeburg County
- Rentals with a kayak Orangeburg County
- Rentals with a washer and dryer Orangeburg County
- Fitness-friendly rentals Orangeburg County
- Apartment rentals Orangeburg County
- Pet-friendly rentals South Carolina
- Pet-friendly rentals United States
- Riverbanks Zoo and Garden
- University of South Carolina
- Congaree National Park
- South Carolina State House
- Columbia Museum of Art
- South Carolina State Museum
- Dreher Island State Park
- Colonial Life Arena
- Saluda Shoals Park
- Columbia Metropolitan Convention Center
- West Columbia Riverwalk Park and Amphitheater
- Williams Brice Stadium
- Riverfront Park
- Edventure
- Sesquicentennial State Park
- Soda City Market




