Pet-friendly vacation rentals in Santee

Find and book unique pet-friendly homes on Airbnb

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Popular amenities for Santee pet-friendly home rentals

Pet-friendly home rentals with a hot tub

Top guest favorite
A front porch features slatted rocking chairs and a decorative door, inviting relaxation. The exterior view of the home displays a charming façade surrounded by a manicured lawn and palm trees. The backyard offers a spacious area with seating around a fire pit and a hot tub beneath a shaded canopy.
Home in Park Circle
4.97 out of 5 average rating, 296 reviews

Home The On Hill - Near Everything Charleston!

AmberRating, 5 stars5 days ago
Everything was exactly as described and the location was FANTASTIC for traveling with small kids. Tamra & Lisa were great communicators ahead of and during our stay, even welcoming us with wine and cheese. Everything was comfortable and the pack n play & high chair on site were a great bonus. The kitchen is fully, full equipped if you like to do some cooking at “home” like we do. There are some fragile items at curious tot level but the living areas are child friendly. Absolutely recommend these hosts and this stay!
Guest favorite
A light-filled living area showcases a large, circular wooden coffee table resting on a decorative area rug. A spacious sectional sofa is arranged nearby, complemented by various decorative pillows. Large windows invite natural light, and a TV is mounted on the wall opposite.
Home in Irmo
5 out of 5 average rating, 9 reviews

The Herons Nest

SaraRating, 5 stars1 month ago
This home worked great for us and our extended family during our son's graduation. Everything was clean and well appointed.
Top guest favorite
An aerial view captures a spacious home surrounded by greenery, featuring a turquoise pool in the foreground. Relaxing lounge chairs line the poolside, while colorful plants add vibrancy against the evening sky transitioning into warm hues.
Vacation home in Summerton
4.97 out of 5 average rating, 99 reviews

Lakefront Paradise W/Pool/hot tub/outdoor kitchen

LaVondaRating, 5 stars5 days ago
This was an absolutely beautiful property! Comfortable, inviting and we loved the game room!! Arriving you are greeted by a gorgeous front yard and and even more impressive backyard with the lake right beyond the fenced in new pool! Wonderful place to make memories. I would recommend!
Guest favorite
A serene lakeside firepit area features Adirondack chairs arranged in a circular formation on a sandy surface. Palm trees stand nearby, framed by a vibrant sunset sky reflecting over the lake. A new dock extends into the water, enhancing the tranquil setting.
Home in Chapin
5 out of 5 average rating, 12 reviews

LakeMurray-Pool-HotTub-GameRm-Beach-FirepitPlaySet

HayleyRating, 5 stars2 weeks ago
Can’t say enough good things about the place. My kids had a blast (almost 6 and 8). When i say they loved it, the LOVED it. The TV “room” upstairs is to die for. Must be a 100 inch tv on the wall. The pool is amazing, hot tub, pool table for the adults, awesome dock (neighbors that can deliver a boat for rent right next door - also super friendly) and great little arcade game set up (my son became quite infatuated with the golf game). Bonus to get to bring my pup who also enjoyed. Truly can’t say enough good things about this place. Plenty of beds (especially if your spouse leaves his CPAP at home). Could easily fit 2 families of 4/5 very comfortably. 10/10. Kids were ready to move.
Superhost
Home in Park Circle
4.85 out of 5 average rating, 447 reviews

Best of Both Worlds with Beautiful Back-Yard Oasis

AnnanRating, 5 stars2 weeks ago
It was really clean and smelled nice. he also provided a lot of towels which was nice. everything worked how expected and the property is beautiful.
Guest favorite
A covered porch extends from the house, featuring a dining table surrounded by several chairs. Potted plants adorn the area, and a swing is positioned for relaxation. The spacious grassy yard is visible, providing ample space for outdoor activities.
Home in Bonneau
5 out of 5 average rating, 40 reviews

Lake Moultrie retreat

HopiRating, 5 stars1 month ago
Amazing stay. The host Marcus was amazing and very considerate. The place itself was clean and in a great location. Highly recommend.
Superhost
A vibrant bedroom features a spacious bed with a blue and white color scheme. Brightly patterned wallpaper enhances the room's character. Large windows allow natural light, complemented by tasteful decor including a desk and seating area. A tray with refreshments sits atop the bed.
Home in Park Circle
4.93 out of 5 average rating, 44 reviews

Hot Tub• Pac-Man•3 Kings•Smart TVs• WiFi • W/D •

MichaelRating, 5 stars1 month ago
The house was spotless, fun, and stocked with everything we needed! It rained the entire time we were in Charleston so I was glad we had an Airbnb with lots of activities (shuffleboard, arcade games, board games, and a hot tub). The three kiddos in the house never got bored. The train noise took some getting used to but we blasted white noise and it was fine. I will say…I would not have been comfortable staying in that neighborhood without my husband/other adults. I did not even feel comfy walking the dog by myself during the day. There was foot traffic from unhoused folks and people going back and forth to the liquor store across the train tracks. That being said, the price was right and it was one of few places in the area that would allow our doggie. My husband and the other baseball dad we traveled with were completely unbothered by the surroundings. The windows and doors locked securely and privacy curtains were on every window. Plus close to nice parks and lots of food options
Guest favorite
An aerial view captures the RV site featuring a spacious, paved patio area surrounded by palm trees. The site includes a fire pit, Adirondack chairs, and a small hot tub, all set against a backdrop of lush greenery. An RV is parked nearby.
Campsite in Ridgeville
4.96 out of 5 average rating, 27 reviews

Luxury RV Campsite Site #2 with Hot Tub

JulieRating, 5 stars2 weeks ago
Spent one day and night at this beautiful location. Would definitely stay again!!! Everything was very well maintained and absolutely breathtaking. We enjoyed a fun walk and fishing, the firepit/grill was easy to use, the landscaping transported us to an oasis, the hot tub was very clean and made for a wonderful wind down after dinner! The bathhouse and outside shower were very clean and so relaxing! I could have easily stayed another week, and can't wait to return!

Pet-friendly home rentals with a pool

Superhost
Home in Park Circle
4.9 out of 5 average rating, 115 reviews

SullyChic 5 Bedroom | Private Lux Pool Park Circl

AriannaRating, 5 stars6 days ago
Everything I hoped and wished for our stay was like the pictures and details! It was a gorgeous home, the bedrooms were comfy and spacious. The kitchen was massive and so perfect for a big group, the backyard with the pool was so beautiful and like a little oasis! It was the perfect distance to downtown, not too far. Such a good stay, definitely will be back!
Guest favorite
A spacious living room features a blue sectional sofa and a large area rug with starfish patterns. A white brick fireplace adds a focal point, and a flat-screen TV is mounted on the wall. Natural light fills the room through nearby windows.
Home in Park Circle
4.91 out of 5 average rating, 128 reviews

Park Circle retreat with King Bed Suite

MaryRating, 5 stars2 days ago
This house was perfect for our family and our dogs. It was super clean and had everything we needed and more! The park within walking distance was awesome too. I would definitely stay here again!
Guest favorite
The living room features a gray sofa set against a light wall, with a round wooden coffee table in the center. Natural light fills the space through large windows, framed by blue and white curtains. A ceiling fan and decorative pieces add a cozy ambiance.
Home in Park Circle
4.91 out of 5 average rating, 148 reviews

Blue Bungalow- 22 min to beach with huge yard

JulieRating, 5 stars2 weeks ago
Very well stocked with towels, kitchen and cleaning supplies! Would recommend
Top guest favorite
A charming cottage with a brick exterior is surrounded by tall trees and bushes. The blue front door provides a welcoming entrance, while large windows on either side allow natural light to fill the interior. The pathway leading up to the home is lined with pine needles.
Guesthouse in Camden
5 out of 5 average rating, 158 reviews

Camden Cottage

BetsyRating, 5 stars1 month ago
This was my second stay at the cottage. It's very comfortable and has everything you need - including a well-equipped kitchen. It's easy to find, very quiet, and dog-friendly. Kathryn and Greg are good communicators and very responsive. Highly recommend and will stay there again in the future if available.
Top guest favorite
A serene evening on the dock showcases a stunning sunset reflecting vibrant hues across the water's surface. Various boats are docked alongside the boardwalk, while gentle waves create a peaceful atmosphere. The sky is adorned with soft clouds, adding depth to the colorful backdrop.
Home in North Charleston
5 out of 5 average rating, 20 reviews

Dream River House at North Charleston

KRating, 5 stars1 week ago
This might be the best vacation rental we have ever had. My grandson liked this vacation more than Disney World. It was the perfect place to relax and just enjoy being with family. Mark was great and available if we had any questions. We will definitely be coming back.
Top guest favorite
A spacious dining area features a large wooden table surrounded by light-colored upholstered chairs. Natural light floods the room through multiple windows, complemented by modern light fixtures hanging above. A glass-front cabinet stands against the wall, providing additional storage and display space.
Home in Park Circle
4.94 out of 5 average rating, 105 reviews

Family Friendly House in Charleston’s Park Circle

WesleyRating, 5 stars2 weeks ago
Beautiful place, extremely responsive and well worth the stay!
Top guest favorite
The community pool is surrounded by a black fence and features a spacious deck with lounge chairs. The water is clear, and a blue pool float is visible. Shade is provided by a sail-like structure overhead, complemented by landscaped greenery in the background.
Townhouse in Mount Pleasant
4.98 out of 5 average rating, 138 reviews

Walk to restaurants, 10min to Chas and Beaches!

CarlaRating, 5 stars1 month ago
The pictures accurately represented her space. We found there was plenty of room for four adults. The kitchen was well stocked with pots and pans, silverware and dishes, something we find to not always be the case. The location was ideal for visiting the beaches and getting to Charleston. Megan was good at making sure we had all the prearrival information we needed and had recommendations on what to do and where to eat. If we were in the area we would stay here again.
Guest favorite
Home in Rembert
4.87 out of 5 average rating, 61 reviews

Pear Tree Farm-pets welcome! Stables/paddocks too!

AnnRating, 5 stars1 month ago
We were there for a girl’s get away and it was perfect. It rained the entire time we were there but it didn’t spoil our time together. There are so many spaces to be cozy and enjoy time together. Just a short drive into Camden or stay on the farm the entire time. Would definitely recommend and hope to get back again! Thanks David for a wonderful get away!

Pet-friendly house rentals

Guest favorite
A well-lit family room features a comfortable seating arrangement, including a light-colored sofa and a blue accent chair. A circular pouf and a wooden coffee table are positioned centrally. Artwork adorns the wall, complemented by natural light from the surrounding windows.
Home in Ladson
4.87 out of 5 average rating, 314 reviews

ROOST. Pet friendly, Clean, Quiet, Comfortable.

MargueriteRating, 5 stars1 week ago
We had a great stay at Michelle's Airbnb. Michael was very helpful with whatever we needed in our 3+ week stay. Thanks for a comfortable and clean place to stay!
Guest favorite
A tranquil view of Lake Marion is captured, featuring calm waters reflecting the sky and surrounding greenery. In the foreground, a wooden dock post is visible, with the shoreline and tree line defining the horizon. Fluffy clouds dot a bright blue sky.
Home in Summerton
4.87 out of 5 average rating, 46 reviews

Santee/Lizzie's Creek Lakefront

KurtRating, 5 stars1 month ago
The house was as advertised. It was right on the lake. The dock had a beautiful view of the lake. The house was well maintained and looked like the pictures. The showers were a little tight, but overall the house was great. Will definitely stay here again on our next trip down to Lake Marion.
Guest favorite
A two-story lakehouse stands among tall trees, featuring a spacious front porch with steps leading to the entrance. Large windows allow natural light to fill the interior, and a charcoal grill sits on the porch for outdoor cooking. The surrounding area is clear of debris.
Home in Elloree
4.85 out of 5 average rating, 41 reviews

Lakehouse

MadisonRating, 5 stars6 days ago
Beautiful get away spot! Perfect location for the boat ramp.
Top guest favorite
A wooden dock extends into calm waters, reflecting the vibrant colors of the sunset. Silhouetted trees frame the scene, which features a serene lake bordered by grassy areas, creating a tranquil lakeside atmosphere.
Home in Cross
5 out of 5 average rating, 13 reviews

New! Lakefront Hideaway | Peaceful & Serene

VickieRating, 5 stars3 weeks ago
Ashley was a great host and the house has everything you need for a relaxing getaway or a good fishing trip! We came in town for a few days fishing and it was perfect for our stay. Very easy to get to boat ramps, and to get around Cross area. Beds are comfortable and everything has been updated and very homey feeling.
Guest favorite
The charming facade of Kuker Cottage is framed by lush greenery and trees, featuring a covered porch with colorful seating. Large windows are positioned symmetrically, and the brick columns add character to the entrance, inviting guests to relax in a tranquil outdoor space.
Home in Florence
4.87 out of 5 average rating, 495 reviews

Kuker Cottage Downtown Florence-Near I95 & I20

DuncanRating, 5 stars5 days ago
Great place to stop in for the night.
Top guest favorite
A private sandy beach area is highlighted, featuring a wooden dock with a blue umbrella providing shade. Two black chairs are positioned on the sand, overlooking a calm lake with clear blue waters and a bright sky.
Home in Summerton
5 out of 5 average rating, 19 reviews

Almost Heaven on Lake Marion, SC

BerdellaRating, 5 stars2 weeks ago
Spacious and comfortable for our group of 6. The kitchen was well equipped for our needs, the back porch had lovely view of the river and was large, breezy, and comfortable with fans. The beds were comfortable with fresh soft linens. Audrey was very responsive to questions but everything worked and we had no issues during our stay.
Top guest favorite
A tranquil lakefront scene captures the soft glow of a sunset over the water, with a wooden dock extending into the lake. A tall tree stands nearby, and a lamppost adds a touch of light. Secluded sandy beach is visible in the foreground.
Home in Moncks Corner
4.81 out of 5 average rating, 146 reviews

Lake Moultrie, Lake front with private dock

AmandaRating, 5 stars1 month ago
Kellie’s place was as amazing as I remembered. This was our 2nd time renting her beautiful lake house & it did not disappoint. The property is so serene & peaceful.
Guest favorite
A spacious cabin-like farmhouse is highlighted by a deep red exterior under evening skies. Front steps lead to a welcoming porch with railings, flanked by large windows that provide views into the interior. Surrounding trees add to the tranquil setting.
Home in West Columbia
4.93 out of 5 average rating, 121 reviews

Farmhouse Living near DT, USC, Ft. Jackson! Pets!

CrystalRating, 5 stars3 weeks ago
It was a very nice place. Looked just like the pictures. Very peaceful and quiet even being off a Main Street. We would definitely use this rental again!

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