Lake house vacation rentals in Santee

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Top-rated lake house rentals in Santee

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Guest favorite

Home in Chapin

4.9 out of 5 average rating, 104 reviews

Lake Murray Family Retreat | BIG Water View Chapin

#lakemurrayfamilyretrrat is a modest and cozy 3 bedroom, 2 bathroom home on an acre lot on Lake Murray, Chapin, SC with BIG views. This 1,355 SF house has a large family room with big lake views, dining room, and the kitchen has peninsula bar seating for four including all major and small appliances. The first bedroom has a queen size bed, the second has a twin bunk + a twin trundle. The Main Bedroom Suite has a queen size bed + TV, walk-in closet, private bathroom, laundry and exterior access.

Dec 8 – 15

G$58,292 GYD per night

Guest favorite

Home in Ridgeville

4.82 out of 5 average rating, 191 reviews

Farm House Lodge at Natural Gathering Grounds

Our homestead and land provides a lovely space for relaxation, peace & quiet and exploration in a natural setting. Our large lodge sleeps 10 guests and is perfect for a local getaway on the Edisto River! Get together with friends, multiple families, or host a retreat! Natural Gathering Grounds has 54 acres of land with trails, fields, fishing ponds, farm animals, and private beach & dock on Edisto River. Just 20 minutes from Summerville and 60 to Charleston, local can have a unique staycation!

Aug 13 – 20

G$30,716 GYD per night

Guest favorite

Home in Aiken

4.95 out of 5 average rating, 228 reviews

Beside Still Waters Country Cottage

Isolated! Peaceful! Amazing Lakefront Property! Gorgeous, fully equipped and thoroughly sanitized 3B/2B getaway on beautiful lake! Dock for fishing & swimming (*) or just enjoying the beauty of it all! Quiet, peaceful haven convenient to downtown Aiken, Augusta, GA, and not too far from Columbia, SC. Amenities include full kitchen, washer & dryer, grill on back deck! Lovely small wedding venue! Convenient to Aiken area horse / equine facilities! *Lifejackets mandatory & available on site.

Oct 23 – 30

G$26,716 GYD per night

Guest favorite

Home in Ridgeway

4.96 out of 5 average rating, 111 reviews

3000 sq ft lake house with views from every window

Lake Wateree 4 bedroom + bunk room with private dock and sleeps 12 comfortably. Our home has been completely renovated and is ready to enjoy! It is located in Ridgeway, SC and 20 minutes from Camden and Lugoff. Colonel Creek Landing is 4 miles away and the perfect location to launch your boat. You can dock your boat in 12 feet of water at our dock. Perfect location for fishing, kayaking and swimming. Two living spaces with smart tv's. Now you can enjoy the fire pit and outdoor shower.

Jan 10 – 17

G$79,859 GYD per night

Guest favorite

Home in Lexington

4.97 out of 5 average rating, 127 reviews

Lakefront home on Lake Murray with private dock

Lakefront home on Lake Murray in Lexington, SC on over 1/2 an acre, 166 feet of waterfront with deep water, private dock, and entertainment space- perfect for an unforgettable vacation or weekend. Entire home for rent-4BR, 3 Bath +2 half baths, 2 sofa sleepers, sleeps 12. Breathtaking kitchen & large living space, perfect for the entire family. 2 single person kayaks, outdoor grill, 65 inch and 55 inch TV, washer/dryer, and fast wifi. Master suite with a lavish bathroom and soaking tub.

Oct 21 – 28

G$103,651 GYD per night

Guest favorite

Home in Columbia

4.95 out of 5 average rating, 127 reviews

Downtown Columbia 3/2 - Entire House

* Entire House on a large lot with no neighbors behind for added privacy * 3 Bedrooms 2 Full Baths * 1.4 miles from PRISMA Hospital (4-minute drive) * NEWLY RENOVATED * BLACKOUT CURTAINS in all the bedrooms * 15 minutes to Fort Jackson * 7 minutes to Riverbanks Zoo * 5 minutes to the Columbia Museum of Art and Soda City Market * Split floor plan with the main bedroom on the right side of the home with on-suite * Open kitchen adjacent to the dining room overlooking the living and sunroom

Jun 29 – Jul 6

G$25,959 GYD per night

Guest favorite

Home in Santee

4.96 out of 5 average rating, 141 reviews

Santee lakefront home, big water right off I-95

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

May 17 – 24

G$90,716 GYD per night

Guest favorite

Home in Gilbert

4.96 out of 5 average rating, 134 reviews

10 Mile View on Lake Murray w/ Dock and Ramp

Enjoy our Waterfront getaway on Lake Murray. It includes a private boat ramp, private dock, and over 600 sq ft deck across the entire lake front of the home. The front yard is large and perfect for cornhole, frisbee, and other activities. This cove is known for excellent kayaking, fishing, boating, and watersports. We have included 2 Kayaks and we work directly with a pontoon rental company if you would like a boat delivered. The .4 acre lot has plenty of parking for all guests.

Aug 11 – 18

G$50,076 GYD per night

Superhost

Home in Moncks Corner

4.78 out of 5 average rating, 130 reviews

Lake Moultrie, Lake front with private dock

Lake front living. Sandy beach and private dock. Children and pets welcome. Enjoy swimming and fishing at your private resort. Local attractions are Old Santee Canal Park, with boardwalk along the Tail Race Canal. Pinopolis Lock, take your boat through the locks and travel to Charleston via intercoastal waterway. Mepkin Abbey, a working monastery and Cypress Gardens with hiking trails and butterfly house are in the area. Or you can simply stay at the cabin to unwind and relax.

Oct 10 – 17

G$47,538 GYD per night

Guest favorite

Home in Ridgeway

4.93 out of 5 average rating, 139 reviews

Enjoy Beautiful Lakefront Views!

IMPORTANT MESSAGE! ! ! Please remember, the Lake Wateree Dam is under a very extensive renovation and hopefully will be completed very soon! However, you can still enjoy viewing the lake from the gazebo and/or local fishing is within 1 to 2 miles from our home (Molly Creek Landing and Dutchman’s Cove) The beautiful new beach is also only within a 2 to 3 minute drive from our property too! Come on and stay anyway! Keeping our fingers crossed the dam is repaired soon!

Dec 23 – 30

G$34,072 GYD per night

Guest favorite

Home in Prosperity

4.99 out of 5 average rating, 136 reviews

Anchors Aweigh

You'll enjoy this small cabin located less than 2 miles from Dreher Island State Recreation Area. The views from the living area and kitchen are breath-taking. You can sit on the dock & watch the sun set or take your boat out just a few hundred yards to watch the sun rise. This location is great for swimming & a dock is available so you can bring your boat. There is also great fishing from the dock and on a boat. This will provide an unforgettable vacation!

Aug 11 – 18

G$31,122 GYD per night

Guest favorite

Home in Summerton

5.0 out of 5 average rating, 81 reviews

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Jan 4 – 11

G$35,814 GYD per night