
Lake house vacation rentals in Santee
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Top-rated lake house rentals in Santee
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Lakefront home with boat ramp and game room
This beautiful home is perfect for your Marion Lake family vacation! With four bedrooms and two living rooms, there is plenty of space! Our home is kid friendly, and includes toys, books, board games, arcade games, foosball, and puzzles. Outside you will find plenty of seating and dining areas, a large yard, a fire pit, a grill, beach along the waterfront, a private dock and a private boat ramp. Perfect for swimming, fishing, and boating! Kayaks are available.

Lakefront w/ dock at Mill Creek
Nestled between Santee & Eutawville, Vance is less than an hour from Downtown Charleston. Experience lake life w/ a front row seat to live music, dancing & karaoke at the Mill Creek Marina! Float over to grab a bite or drink at the Barefoot Lakeside Bar & Mill Creek Food & Spirits! Community hosts golf cart parades, Halloween bash, & a spectacular 4th of July fireworks show. Launch your pontoon a few doors down, tie up at your dock & conveniently fuel up at the marina. Campground store on site!

Lake House at Lake Marion
Beautiful lakefront 3 Bedrooms/2 full baths with million dollar view of Lake Marion. -2 Queen beds/2 twins/1 futon -Washer/Dryer -Screened porch -Private Dock - fish in “big water” -Canoe & Kayak -Fire pit -Includes linens & beach towels & more! -Fully Furnished + grill & carport -One level open concept -75” Roku TV & Roku in Master and WiFi -great safe neighborhood for walking & bike riding -NO HOUSE PARTIES or events. -public boat landing &county park with playground within 2 blocks.

Lakeview Leisure-Face to the Sun
At this unique and tranquil getaway, your day can be whiled away on the porch, poolside or in the hot tub. Or pack a cooler and spend the day on Lake Marion. Tie your boat off on the dock and head just down the road to Santee for a round or two at Santee National Golf Club. Located conveniently between Columbia and Historic Charleston you are never out of options to stay as busy as you like. End the day with a cocktail on the back porch, steaks on the grill and a game of pool. Enjoy life!

Heated Indoor Pool on Lake Marion with Dock
Lake Marion Lakefront on a private 2.5 acres. Two houses - 4500 sq. ft. of space, plenty of room for 14! Dock to fish off of or bring your fishing boat. Heated indoor pool and Margaritaville-themed bar. Firepit, pool table, games, and dining table for 14 people. Great spot for Family Gatherings or Friends' Getaway. Golf, fishing, fruit picking, and amazing country food restaurants - 25 min drive. 5% Discount Gov. Employees :) Parties over 14 ppl ++ fees apply, details discussed prior.

Luxurious Lakefront Log Home W/Pool & hot tub
Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Stylish Lakefront Group Getaway Sleeps 8
Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

10 Mile View on Lake Murray w/ Dock and Ramp
Enjoy our Waterfront getaway on Lake Murray. It includes a private boat ramp, private dock, and over 600 sq ft deck across the entire lake front of the home. The front yard is large and perfect for cornhole, frisbee, and other activities. This cove is known for excellent kayaking, fishing, boating, and watersports. We have included 2 Kayaks and we work directly with a pontoon rental company if you would like a boat delivered. The .4 acre lot has plenty of parking for all guests.

Perfect Family Retreat at Lake Marion
Great water front family escape! Enjoy our beach, dock and boat ramp as well as our game room and fully stocked kitchen. We purchased our home is 2006 and began a complete interior and exterior renovation. In 2023 we installed solar panels and an electric vehicle charging station, yet we also have access to the grid for cloudy days and when power demand exceeds what our panels generate. We use a deep well for water. Bring your family for an off-the-grid vacation in our lake home!

Fish Haven I
Looking for a quiet, yet charming lakeside property? Look no further! Come enjoy this three-bedroom home with direct access to the diversion canal and a private boat launch. Great space for fisherman, families or couples. Ample space for your boat and hitch. Enjoy your days fishing, savor your afternoon by having a beverage and grilling out on the back patio. Spend the evenings playing cornhole and relaxing by the fire pit. It is the perfect setting to create wonderful memories!

Cheerful 3 bedroom home on the lake
Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Ultra Modern Lake Murray Villa | Magnificent Views
This Ultra Modern Lake House is beautifully built and ready for summer fun! ★ Located directly on Lake Murray in Gilbert, SC ★ Ultra modern interior design and furnishings ★ Breathtaking views of the lake ★ Lake, dock, and boat ramp access ★ Outdoor entertaining space ★ SmartTVs in Living Room ★ Fully equipped & updated kitchen ★ Gated driveway parking ★ 1 King + 2 Queens + 2 full bathrooms ★ 1 Boat spot at dock ★ Gas grill
Popular amenities for Santee lake house rentals
Waterfront lakehouse rentals

Eagle Point Sunset Retreat

Lakefront Fishing + Grilling | Home Sweet Home!

Cutest Cottage on the Lake

Lake House Getaway

Peaceful lake house near Columbia - sleeps 7

Lake Marion Beauty w/ 5br/3ba

Mark it Lake, Dude!

Cozy Church Branch Cabin
Pet-friendly lake house rentals

Santee/Lizzie's Creek Lakefront

Tie One On! at 4 Bdr Waterfront Lake Marion

The Cypress House

Almost Heaven on Lake Marion, SC

Lake Marion Cottage

Fisherman's Dream at Low Falls Landing-Lake Marion

Large Lakefront Home w/360 view, beaches, & dock

Carolina Cottagecore
Private lake house rentals

Beautiful and spacious 5/3, near I95 /I 26.highway

The Fishnet

A Lake Slice of Heaven

A Secluded Space (Downstairs)

Lake Moultrie retreat

SANTEE LAKE MARION GOAT ISLAND AREA NEWLY UPDATED

Edisto River*Dock&Boat Landing*13 guests

Lakefront Retreat | Dock, Firepit & Pet Friendly
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- Congaree National Park
- Riverbanks Zoo and Garden
- University of South Carolina
- North Charleston Coliseum & Performing Arts Center
- Middleton Place
- Magnolia Plantation & Gardens
- South Carolina State House
- Williams Brice Stadium
- South Carolina State Museum
- Charleston Southern University
- Cypress Gardens
- Colonial Life Arena
- West Columbia Riverwalk Park and Amphitheater
- Columbia Museum of Art
- Sesquicentennial State Park
- Columbia Metropolitan Convention Center
- Edventure
- Wannamaker County Park
- Riverfront Park
- Whirlin' Waters Adventure Waterpark
- Soda City Market
- Koger Center for the Arts
- Segra Park
- Bee City Zoo & Honey Bee Farm





