Lake house vacation rentals in Santee

Cozy Church Branch Cabin

A cozy lakefront cottage made by family, for family. This was our parents home away from home, their favorite getaway. Now that they're gone, we want to share what they enjoyed. Traditionally constructed lake cabin with all the comforts of home. Large partially covered deck, large pier for fishing, plenty of room to bring your boat, canoes, or kayaks. Extremely close proximity to large landings where national fishing tournaments are held on Lake Marion. Prime hunting, near great hunting clubs.

Lake Murray Family Retreat | BIG Water View Chapin

Lake Murray Family Retreat is a modest & cozy 3 bedroom, 2 bathroom home on an acre lot on Lake Murray, Chapin, SC with BIG views. We put a lot of thought into furnishing this home and had families in mind with each detail. It isn't the most updated or fanciest home on the lake, but it's one of the homiest! ★ 2 Queen beds + 3 twin beds (1 bunk + trundle) ★ 2 Full bathrooms ★ Smart TVs in the living room & primary bedroom ★ Gas fireplace ★ Firepit ★ Laundry area ★ Parking for 2 boats at dock

Lakefront Lookout

The best panoramic views of Lake Marion! Whether you're out on the porch or indoors in our air-conditioned unit, you will not miss out on the beauty of the lake. Our updated kitchen and two full bathrooms are stocked with all the essentials. Hop on a boat, swim in the community pool, fish, walk, run, or bike the pedestrian bridge, or just hang out with your company while watching the boats go by. Please respect the fact that there is a small pet fee and we’re alerted when pets are present.

Cozy 3 Bedroom Lakefront Home on Lake Marion

Cozy 3 bedroom waterfront vacation rental on gorgeous Lake Marion. Come enjoy the beautiful lake view and the many activities that Lake Marion has to offer, including boating, fishing, watersports, golfing and wildlife viewing. Recently updated with new flooring, wifi and DirecTV with movie channels. This spacious home has everything you need to get the most from your vacation! Home is just off the big water, about 5 houses in on a small canal so you'll be seconds away from big water fun.

Nanny’s Lake Retreat

Located in a quiet, dead end community. Enjoy the lake sounds from the spacious screened in porch. The porch has a swing, rocking chairs, and table with chairs. The den boasts a beautiful gas log fireplace and has two futons and a loveseat. The house is located in a golf cart community on a cove. Sandy beaches are just minutes away depending on the lake levels. Whether you’re looking for a vacation destination or fishing/hunting trip you will love this home. Pets require pre approval

Luxurious Lakefront Log Home W/Pool & hot tub

Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Santee lakefront home, big water right off I-95

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Perfect Family OFF THE GRID retreat at Lake Marion

Great water front family escape! Enjoy our beach, dock and boat ramp as well as our game room and fully stocked kitchen. We purchased our home is 2006 and began a complete interior and exterior renovation. In 2023 we installed solar panels and an electric vehicle charging station, yet we also have access to the grid for cloudy days and when power demand exceeds what our panels generate. We use a deep well for water. Bring your family for an off-the-grid vacation in our lake home!

Fish Haven I

Looking for a quiet, yet charming lakeside property? Look no further! Come enjoy this three-bedroom home with direct access to the diversion canal and a private boat launch. Great space for fisherman, families or couples. Ample space for your boat and hitch. Enjoy your days fishing, savor your afternoon by having a beverage and grilling out on the back patio. Spend the evenings playing cornhole and relaxing by the fire pit. It is the perfect setting to create wonderful memories!

KING Beds - Bungalow Downtown Cola

* KING Beds in both bedrooms * PET FRIENDLY * EV CHARGER PLUG (4 Prong outlet ONLY, no cord or adapter) * TVs in both bedrooms and living room * 1.4 miles from PRISMA Hospital (4-minute drive) * BLACKOUT CURTAINS in all the bedrooms * 15 minutes to Fort Jackson * 7 minutes to Riverbanks Zoo * 5 minutes to the Columbia Museum of Art and Soda City Market * HUGE Deck with table and small covered area * Off-street parking pad for 5+ cars * 11-minute drive to Lexington Medical Center

Cheerful 3 bedroom home on the lake

Great 3 bedroom home on the water. Perfect for family vacations, a weekend getaway or a stay for local fishing tournaments. This home is on a quiet cove that opens up to the larger lake. Get the best of both worlds. The cove is perfect for paddle boating, kayaking, fishing off the dock, grilling on the deck, or just relaxing on the screened porch enjoying the view. But, with the private dock you can bring your boats and jet skis to enjoy the entire lake.

Carolina Cottagecore

🌞 An amazing Airbnb in Summerton, SC, just 10 mins from Lake Marion. 3 bedrooms, 2 bathrooms, sleeps 8. Stylish decor, fully equipped kitchen, cozy living area. Outdoor paradise with lush greenery. We do accept pets but there is a $498 charge per pet with max of 2. Don't miss out on this unforgettable getaway! Book now! 🌟💫 #Airbnb #SummertonSC #LakeMarionGetaway