
Family-friendly vacation rentals in Santee
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Santee
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Mulberry Cabin, a rustic tiny house cabin
Mulberry Cabin is conveniently located halfway between Charleston and the capital city of Columbia in Rowesville, SC. Please note the cabin is located in a small town, not in the country. Rowesville is 11 minutes from the beautiful Edisto Memorial Gardens in Orangeburg. Orangeburg has many restaurants, Wal-Mart, and a Starbucks near I-26. Columbia is about an hour away. Charleston is about 75 minutes away. Enjoy a break from Wi-Fi as you watch a DVD and relax in a 130 year old rustic cabin.

Restful Lakeside Getaway Cottage -Dogs allowed
This pond-side cottage is a peaceful place to relax and unwind. Sit on the enclosed porch and watch the water or enjoy the front porch swing where you can listen to the birds and frogs. We are 12 min. from downtown Sumter and 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens and Poinsett State Park. It is only 2 hours to Myrtle Beach and Charleston, SC & 3 hrs to the mtns. While it is conveniently located, this cottage offers a quiet place to put your feet up and rest.

Relax and unplug at this private oasis!
Our beautiful cottage for adults only is set on a private spring fed pond with all amenities to unwind from the day-to-day hustle. A porch with rocking chairs, brick fire pit and outdoor lighting in the courtyard make this your destination for relaxation. Take a walk in the 20 acres of wooded trails, fish, kayak, paddleboat, read a book, write, listen to music or just take a nap. This property lets you unplug from the world, relax, and connect with nature without giving up modern conveniences.

Archie's Lake Daze Cottage No pets
Soak up the beautiful lake views from a rocker on the porch or the 2-person hammock between the pine trees. This cozy cottage has 3 BR and 2 Baths and a stocked kitchen to make you feel right at home. Enjoy fishing from your private dock or take a spin in the paddle boat or kayaks provided. After a long day on the lake, you can enjoy a game of pool, classic arcade games, darts, or board games. WiFi is provided as well as 3 smart TVs. There is plenty of parking for your vehicles and water toys.

Lakefront Lookout
The best panoramic views of Lake Marion! Whether you're out on the porch or indoors in our air-conditioned unit, you will not miss out on the beauty of the lake. Our updated kitchen and two full bathrooms are stocked with all the essentials. Hop on a boat, swim in the community pool, fish, walk, run, or bike the pedestrian bridge, or just hang out with your company while watching the boats go by. Please respect the fact that there is a small pet fee and we’re alerted when pets are present.

The Boho Barndo
Take it easy at this unique and tranquil getaway. The Boho Barndo is the perfect spot to get away. Well stocked to make your stay comfortable. We are just 20 min from Downtown Summerville, 30 min from the Charleston International Airport and 5 min from shopping and dinning. The barndo is located on a large 5 ac. tract. The entrance is gated and you will have your own designated parking area. The main house is located about 250 yrds away from the barndo and allows you to enjoy peace and quite

Log home on Lake Marion inlet w/private dock.
Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

The Little Cottage, Stateburg
Take it easy at this unique and tranquil getaway. The Little Red Cottage features a small bedroom with a double size bed and a closet, a spacious living room with sofa/roku TV and computer desk, and a bathroom with shower. It is nestled on 6 serene acres, among massive windswept Live Oaks dripping with Spanish moss, Palmettos, azaleas, camellia, magnolias and creape myrtle, yet so conveniently close to Shaw Air Force base, 30 mins to Columbia and Camden, close to all Sumter's attractions.

Relaxing Comfortable Waterfront Family Dock Suite
Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Luxurious Lakefront Log Home W/Pool & hot tub
Stunning luxury log home on the big waters of Lake Marion, featuring a private fishing pier, boat dock, brand-new saltwater pool, hot tub, and more. This custom-designed retreat offers 3 spacious bedrooms, a loft, and 2 elegant bathrooms—one with a clawfoot soaking tub and separate water closet. Enjoy dining and entertaining on the expansive screened-in porch with a custom 12’ outdoor bar. Just 6 minutes from I-95, this serene lakeside escape blends rustic charm with upscale comfort.

Santee lakefront home, big water right off I-95
Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Pet-Friendly Lake Marion Getaway - Just off I-95!
In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.
Popular amenities for Santee family-friendly rentals
Family-friendly home rentals with a hot tub

magical 1840s farm house getaway

Sunset Serenity Pool/Swim Spa

Lakeview Leisure-Face to the Sun

The Indigo - 2BR w/Hot Tub & Outdoor Space

Luxury Treehouse in the heart of Columbia

Lake Murray Paradise~2 BR, 1 Bth, Kit/Living area.

Luxe Lake Marion Oasis with Pool/Hot Tub/Dock

Lakeside Dreams W/Pool & Spa
Family- and pet-friendly home rentals

Welcome! a relaxing retreat...home away from home

Southern Charmer 3 BR/Wrap around porch, fire pit

New Home! Only 15 min to Shaw/Sumter. Dog friendly

Congaree Vines - Woodland Cottage by a Vineyard!

Bungalow on Bobs

Downtown Blue BoHo w/ outdoor spaces, grill & FP

The Cabin at Minehill

Charming Tiny House, 5 minutes to I-26
Family-friendly home rentals with a pool

Eagle Point Poolside Escape

The Cottage for Two

Colonial Farmhouse - 6 bedroom with a pool

Updated 2BR condo with balcony

Das Gästehaus w/Pool Access

Lavish Home 4BR/3BA, King, Games, Grill, Pool!

Splendorous Spoleto Ln.

Eagle Point Retreat W/Pool
Quick stats about vacation rentals that are family-friendly in Santee

Total vacation rentals
Explore 30 vacation rentals in Santee

Nightly prices starting at
Santee vacation rentals start at G$20,920 GYD per night before taxes and fees

Verified guest reviews
Over 150 verified reviews to help you choose

Vacation rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Santee vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santee rentals

4.9 Average rating
Santee stays are highly rated by guests—averaging 4.9 out of 5!
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- Riverbanks Zoo and Garden
- Middleton Place
- South Carolina State House
- Congaree National Park
- Magnolia Plantation & Gardens
- Columbia Museum of Art
- University of South Carolina
- South Carolina State Museum
- Cypress Gardens
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- West Columbia Riverwalk Park and Amphitheater
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