
Family-friendly vacation rentals in Mississippi River
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Mississippi River
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Dana's Retreat-glamping/camping @ a WildlifeRescue
Reconnect with nature at this unforgettable escape. Located at 2nd Hand Ranch & Rescue, this tiny house in the timber was built to share the beauty of nature with folks that want to camp.... but not really camp. This 12x12 house is off grid with a cute outhouse nestled in the timber behind the wildlife rescue. Relax and unplug for the weekend and know 100% of the fee goes to the animal rescue. We bring your supplies up via Gator as you hike the trail up. PLEASE NOTE: NO RUNNING WATER/SHOWERS
Indoor spacesFamilyNearby
5.0 out of 5 average rating, 144 reviews
Yeary Farms Milt's Place with Private Beach!
An Ozark Oasis in the middle of a working cattle ranch, this custom designed home offers deluxe comfort. With multiple decks, porches and views out every window, this home is the perfect getaway for romantic retreats, family and friends to relax and make memories, artists and writers to host workshops or retreats, or even the single person to just get away from it all. Good dogs welcome, $35 per dog per week, fee collected separately at time of check in. Look for Yeary Farms site for more info.
FamilyIndoor spacesBathroom
4.98 out of 5 average rating, 174 reviews
The Fair House: Tiny Home on Price Coffee Rd.
Charming and unique, the Fair House has a lot to offer within a small footprint! Tall ceilings, a roomy loft, two bedrooms, and a full kitchen/bath - you will have all you need for a relaxing get-away. Located on beautiful Price Coffee Rd, our place is ideal for anyone seeking a peaceful retreat that is still only minutes from downtown. Enjoy the large covered porch, fire pit, and 3 acres to spread out. Custom designed, the Fair House is a great place to relax for couples, families, or friends!
FamilyIndoor spacesSolo travel
5.0 out of 5 average rating, 313 reviews
Tiny house on an organic flower and vegetable farm
Located on MIllsap Farm which is home to one of Springfield's favorite summer activities; Thursday Pizza Club. Come stay in our Tiny Turtle countryside cabin and get a taste of farm life on this small organic veggie farm. Take a walk in flower patch, visit the chickens, feed your scraps to the pigs, throw the ball for the dogs, be entertained by the farm happenings. Our tiny home is well designed and can easily host a family. The farm stand is stocked and ready for you just outside your door.
FamilyIndoor spacesLocation
4.94 out of 5 average rating, 365 reviews
Private Spring Fed Reservoir w/paddle boat
Off the beaten path, approximately 1 mile down a bumpy dirty road you will find a hidden gem. At the edge of the Ozarks in the heart of green country is a small cottage located on a beautiful one acre spring feed pond. You can see the spring gushing out of the hillside. Our cottage is small, cozy, and very relaxing. Whether you are kicking back watching the tube or paddling around the pond you will feel right at home and may not want to leave. Paddle boat, 4 paddle boards and 2 kayaks included
Indoor spacesKitchenParking
4.99 out of 5 average rating, 169 reviews
The Grainery with Hot Tub
Welcome to the Grainery! This is a uniquely built grain bin for four, tucked in the edge of the forest in the Ozark Hills. Bring along your smores and enjoy roasting them over a beautiful wood fire and count the stars as you relax in a soothing spa. Need more space, bring an RV with full hook up available for an extra $50 a night. We hope you have a peaceful and enjoyable stay in God’s creation. If The Grainery is not available check out our neighboring Airbnb called The Silo Suite & Jacuzzi.
FamilyKitchenGrill
4.99 out of 5 average rating, 160 reviews
The Blue Door Cabin
If you want a retreat where you can sleep in, slow down and savor nature's beauty, the Blue Door Cabin, tucked in surprisingly hilly oak and hickory woods, with a beautiful view of the pond, is your destination. Within two hours from Kansas City, Tulsa, Joplin or Wichita, and only 4 miles from Chanute Kansas, this preserved and revived cabin offers an easy getaway for city dwellers in need of a very affordable anniversary weekend, study or solitude retreat, or family hiking and fishing trip.
KitchenFamilyLayout
4.98 out of 5 average rating, 622 reviews
The Treehouse is a quiet and peaceful retreat.
Tropical Treehouse set in a ten acre Jungle Garden with a canal lagoon. Private mature forest park of 250 acres and five miles of nature trails. There are four lakes and the Treehouse overlooks Lake Winnamocka. The house is 35 feet in the air accessible by stairs but with a cargo lift for luggage and groceries. The bath is tile with heated floor and tile shower. There is a bidet, washer/dryer in the full bath. The kitchen is modern. There are 3 porches. Master bed and two loft bunks.
KitchenIndoor spacesRiver
5.0 out of 5 average rating, 260 reviews
Locust Mountain View
This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!
KitchenFamilyLayout
4.95 out of 5 average rating, 155 reviews
Quiet little farm stay in Austin - pet friendly
Welcome to our little old farmhouse. 🏡❤️ If you love being greeted by friendly, nosy sheep, then this is the place for you! Welcome to our little farm, where we love making our guests feel right at home. This is a place to slow down, relax, and unwind from the hustle and bustle of everyday life while enjoying a little taste of simple farm living. Come as a guest, relax like you’re at home, and leave with a few memories—and hopefully a little love for our farm family. 🐑🐐🐴✨ .
FamilyIndoor spacesBathroom
4.99 out of 5 average rating, 671 reviews
Lost Valley View Cabin
Enjoy this cozy cabin nestled in the heart of the Ozarks. With a view of Lost Valley and beyond, the front porch is a nice place to relax and unwind! With a full kitchen, fire pit, horseshoe pit, charcoal grill, and more we wish you to be able to vacation deliberately, comfortably, and affordably! Please hit us up with any questions and thank you! We do have Pyrenees dogs who watch over the farm, they are harmless and just part of the landscape. Firewood for sale, 5$ an arm load!
Indoor spacesKitchenHiking
4.96 out of 5 average rating, 647 reviews
Out On A Limb Treehouse
A unique Treehouse, 6 miles from Hermann, MO, offers a luxury escape with stunning views and sunsets. Perched on stilts by Daniel Boone Conservation Area, enjoy tranquility, hiking, and wildlife. Relax in a king-size bed beneath skylights, soak in a tub, or unwind in the hot tub and firepit. Just a mile from the Katy Trail, perfect for cycling or relaxing. Explore Hermann’s wineries, shops, and events. Transportation available from Hermann Trolley, Uber & Lyft. Sleeps 2 adults.
Indoor spacesFamilyOutdoor spaces
4.99 out of 5 average rating, 178 reviewsPopular amenities for Mississippi River family-friendly rentals
Family-friendly home rentals with a hot tub

Ultimate Fall Getaway - Firepit, Hot Tub, Trails
KitchenFamilyParking
4.97 out of 5 average rating, 286 reviews
Treehouse in the Ozarks w/Hot Tub, on 2 Acres
Indoor spacesFamilyBathroom
4.98 out of 5 average rating, 273 reviews
Geodesic Sunset Dome at Three Ponds Community
Indoor spacesFamilyComfort
4.89 out of 5 average rating, 248 reviews
Luxury Cabin Sleeps 6 w/ Hot Tub and Outdoor Movie
KitchenIndoor spacesCheck-in
4.99 out of 5 average rating, 171 reviews
River Cabin/UTV/Trails/Kayaks/HotTub/OutD Shower/
Indoor spacesFamilyGetting around
4.98 out of 5 average rating, 320 reviews
The Wilderness Homestead Cave-HotTub-Hiking
FamilyIndoor spacesBathroom
4.94 out of 5 average rating, 258 reviews
Highlands Retreat | Luxury Cabin w/ Mountain View
FamilyIndoor spacesValue
5.0 out of 5 average rating, 179 reviews
Romantic Treehouse-Hot Tub- Arcade/No Cleaning Fee
Indoor spacesFamilyQuiet
4.99 out of 5 average rating, 279 reviewsFamily- and pet-friendly home rentals

Nauvoo Halfling House
FamilyKitchenSleep quality
4.97 out of 5 average rating, 118 reviews
Restful Rustic Comfy Cabin.
KitchenFamilyBackyard
4.94 out of 5 average rating, 542 reviews
Log Cabin at Meramec Farm
KitchenIndoor spacesNearby
4.93 out of 5 average rating, 518 reviews
Cabin on the Creek, 120 Acres
FamilyIndoor spacesCheck-in
4.98 out of 5 average rating, 291 reviews
Robber's Roost Tree House at Beautiful SundanceKC Lake Retreat
FamilyKitchenBeach
4.96 out of 5 average rating, 357 reviews
Celestial Log Cabin on the Confluence
FamilyIndoor spacesComfort
4.97 out of 5 average rating, 101 reviews
The Crows Nest
Indoor spacesFamilyHiking
4.96 out of 5 average rating, 106 reviews
Peaceful Treehouse at Nature Resort w/ Amenities
KitchenFamilyNearby
4.95 out of 5 average rating, 140 reviewsFamily-friendly home rentals with a pool

Upscale country living at its finest! Pool,HotTub
Indoor spacesFamilyBeach
4.96 out of 5 average rating, 442 reviews
Tan-Tar-a Resort Home
KitchenFamilyWalkability
4.99 out of 5 average rating, 189 reviews
The Hideaway
KitchenFamilyCondition
4.99 out of 5 average rating, 502 reviews
Melrose Grove: Pool, Tiki Lounge, Barrel Sauna
Indoor spacesKitchenWifi
4.95 out of 5 average rating, 490 reviews
Tiny Paradise on the Quarry
FamilyIndoor spacesLocation
4.95 out of 5 average rating, 582 reviews
🦌 Deer Hill a LR Country Estate Est. In 1938 🫶🏼
KitchenFamilyValue
5.0 out of 5 average rating, 146 reviews
The Cottage: Luxurious Getaway!
KitchenIndoor spacesBathroom
4.97 out of 5 average rating, 123 reviews
Octagon treehouse Hottub-pool-fireplace-firepit
Indoor spacesKitchenCondition
4.99 out of 5 average rating, 245 reviewsDestinations to explore
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