
Family-friendly vacation rentals in Mississippi River
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Mississippi River
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

Cossatot River Treehouse (Fish, ATV and bike ride)
A cozy treehouse nestled on the banks of the Cossatot River. The cabin is on 3 secluded acres. This two-bedroom, two-and-a-half-bath cabin offers a large screened-in porch with a queen-size swing bed for ultimate relaxation by the river. Enjoy the outdoor deck equipped for grilling and gather around the firepit for family fun. Fishing, swimming, kayaking, hiking, ATV and bike riding are all available right from the cabin. Come visit and enjoy the modern comforts of this unique riverside retreat

Yeary Farms Milt's Place with Private Beach!
An Ozark Oasis in the middle of a working cattle ranch, this custom designed home offers deluxe comfort. With multiple decks, porches and views out every window, this home is the perfect getaway for romantic retreats, family and friends to relax and make memories, artists and writers to host workshops or retreats, or even the single person to just get away from it all. Good dogs welcome, $35 per dog per week, fee collected separately at time of check in. Look for Yeary Farms site for more info.

Private Spring Fed Reservoir w/paddle boat
Off the beaten path, approximately 1 mile down a bumpy dirty road you will find a hidden gem. At the edge of the Ozarks in the heart of green country is a small cottage located on a beautiful one acre spring feed pond. You can see the spring gushing out of the hillside. Our cottage is small, cozy, and very relaxing. Whether you are kicking back watching the tube or paddling around the pond you will feel right at home and may not want to leave. Paddle boat, 4 paddle boards and 2 kayaks included

A Luxury Treehouse Experience | Wood-Fired Cedar Hot Tub
Welcome to Whitetail & Pine, a Luxury Treehouse Experience. Nestled in the branches of two centuries old red oak trees and suspended 25 feet above Goose Creek, this arboreal abode offers a unique twist on traditional lodging. If you are seeking a rejuvenating getaway accented with the sights and sounds of nature, yet desire to be close to Fayetteville’s best restaurants and attractions, look no further than the Treehouse @ Whitetail & Pine. If you are on the fence, check out our reviews!

Ponderosa Cabin South of Fayetteville
Make some memories at this family-friendly mountaintop cabin south of Fayetteville. This unique cabin is located on 50 acres that offer a million-dollar view of the Boston Mountains. Enjoy fishing in the large pond with the fishing poles, tackle, and enjoy the challenge of a scavenger hunt along the 1/2 mile-long hiking trail! In the evening, enjoy the cliffside firepit nestled next to the peaceful waterfall! 11-minute drive to Razorback Stadium and 5 minutes from the interstate!

Locust Mountain View
This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!

Private Treehouse Retreat | Hot tub
The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.

Lost Valley View Cabin
Enjoy this cozy cabin nestled in the heart of the Ozarks. With a view of Lost Valley and beyond, the front porch is a nice place to relax and unwind! With a full kitchen, fire pit, horseshoe pit, charcoal grill, and more we wish you to be able to vacation deliberately, comfortably, and affordably! Please hit us up with any questions and thank you! We do have Pyrenees dogs who watch over the farm, they are harmless and just part of the landscape. Firewood for sale, 5$ an arm load!

Out On A Limb Treehouse
A unique Treehouse, 6 miles from Hermann, MO, offers a luxury escape with stunning views and sunsets. Perched on stilts by Daniel Boone Conservation Area, enjoy tranquility, hiking, and wildlife. Relax in a king-size bed beneath skylights, soak in a tub, or unwind in the hot tub and firepit. Just a mile from the Katy Trail, perfect for cycling or relaxing. Explore Hermann’s wineries, shops, and events. Transportation available from Hermann Trolley, Uber & Lyft. Sleeps 2 adults.

The Highland Bin at Haywire Acres, Highland Cows
Welcome to our charming boho-inspired Grain Bin Cabin, the Highland is ideal for 2-3 adults or 2 adults and 2 smaller children. Upstairs, you'll find a comfortable king bed in the loft, while downstairs features a cozy futon in the main living space. The full kitchen is equipped with everything you need. Full Bath with a walk-in shower downstairs. Experience a serene countryside getaway with breathtaking sunsets and peaceful surroundings, just moments away from Versailles.

Sassafrass Silo Treehouse on Table Rock Lake
The Sassafrass Silo began life as a grain silo that Mike found on a farm in Kansas. We felt she had more life left in her, so we took her from field to forest and gave her a new purpose! Her new journey is based on Debbie's family history from the beautiful Natchez, Mississippi. Her memories of serving in Pilgrimage in her own hoop skirt and classic charm of the antebellum homes paired with her love of bohemian style, nature and the lake helped create this unique space!

Luxury Lakeview Treehouse • Stunning Views • Lake
Welcome to Tree + House II at Indian Point! This modern, luxurious treehouse is designed to accommodate up to four guests and offers a serene retreat in a peaceful forest setting. Featuring stunning floor-to-ceiling windows, you’ll enjoy spectacular views of Table Rock Lake right from your cozy hideaway. Conveniently located just minutes from Table Rock Lake and Silver Dollar City, it’s the ideal destination for both relaxation and adventure.
Popular amenities for Mississippi River family-friendly rentals
Family-friendly home rentals with a hot tub

Stargaze. Soak. Unwind. S’mores. Repeat

Geodesic Sunset Dome at Three Ponds Community

Cozy Treehouse / Hot Tub / Farm Animals / Hiking

Casa Bella*15 mis to Bentonville*Hot tub*

Beautiful 1 bedroom treehouse with hot tub/ views

TreeHouse, Hot Tub, Views, Lake

Secluded Lakefront Estate | Couples Retreat

Romantic Treehouse-Hot Tub- Arcade/No Cleaning Fee
Family- and pet-friendly home rentals

The Treehouse is a quiet and peaceful retreat.

Nauvoo Halfling House

River Roots Cabin

Peaceful Treehouse at Nature Resort w/ Amenities

The Moonshack - An Off Grid Experience on 50 Acres

Cabin on the Creek, 120 Acres

Robber's Roost Tree House at Beautiful SundanceKC Lake Retreat

The Stargazer Cabin
Family-friendly home rentals with a pool

Secluded Luxury | Heated Pool, Hot Tub & Fishing

The Winsome Loft- Arcade & Home Theater

The Hideaway

Cozy Cabin Retreat

MILO FARM-Sacred Kansas City Retreat

Tiny Paradise on the Quarry

The Cottage: Luxurious Getaway!

Country Paradise •9 acres•Pool•Rec Center
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