House vacation rentals in Mississippi River

Find and book unique houses on Airbnb

Top-rated house rentals in Mississippi River

Guests agree: these houses are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Top guest favorite
The rustic exterior of the cabin showcases live-edge cedar siding and a spacious front deck with wooden railing. Surrounding trees indicate the natural setting, while the gravel driveway leads to an unobstructed view of the creek nearby.
Home in Houston
5.0 out of 5 average rating, 109 reviews

Brushy Creek Cabin

Back to basics. Enjoy the peaceful solitude of this creek side home on the edge of town. This rustic remodel has modern amenities, including wi-fi, to make your stay comfortable and cozy. There are also areas for relaxation, like the hot tub on the deck. While soaking, you can view the creek which often has wildlife such as otters, beaver, deer, squirrels, owls and herons. When the weather is warm, cool off by splashing around in the creek. It's your time to unwind at the Brushy Creek Cabin.

Guest favorite
Home in Gray Summit
4.88 out of 5 average rating, 222 reviews

Sunset Mountain Privacy

Along Route 66, just 4 minutes from Purina Farms, this shared property is dedicated to your privacy, where you’ll enjoy a jacuzzi tub, private deck, 3 bedrooms, 2 full baths, gas fireplace, fully stocked kitchen, fenced in area for dogs, relaxing garden areas, walking trails through the woods, fire pit, and an above ground pool in the summer months. Great for weekend getaways and anyone wanting to unplug. I stay in lower level with my husband and 11 year old son (who is usually gone weekends).

Top guest favorite
A hot tub sits on a wooden deck, overlooking a calm river. Gentle waves are created in the water, while greenery is visible along the shore. A wooden railing frames the view, enhancing the sense of tranquility and connection to nature.
Home in Pleasant Valley
5.0 out of 5 average rating, 180 reviews

Mississippi River House

Now is a great time to stay in this completely furnished two-bedroom house directly overlooking the Mississippi River. The hot tub is amazing during the day and under the stars this time of year. Eagle watching in the winter is always entertaining while relaxing in the hot tub. This 1+ acre property is tucked away on a private dead end street, yet close to many great restaurants and shopping. If you're looking for a romantic getaway this house has everything you need for a wonderful time!

Top guest favorite
A single-story house is situated on a green lawn, with mature trees providing shade. Light blue chairs are arranged on the porch, creating a welcoming outdoor space. An American flag is gently waving in the breeze, complementing the peaceful surroundings.
Home in Lesterville
4.95 out of 5 average rating, 113 reviews

The Black River Oasis on the Middle Fork

Freshly renovated house, with an added kids / game room that has a pac man arcade with 60 total games. Overall the house will sleep a total of 12. Perfect for 2 or 3 families to get away and enjoy the beautiful Black River. Private beach area to kick back and relax with no cares in the world. Only 7 miles from Johnson Shut Inns. Also near by is Elephant Rock and Mark Twain National Forest! We are pet friendly but do charge extra for pets. It’s is your responsibility when booking to list a pet.

Top guest favorite
The two-story home is surrounded by lush greenery and is complemented by seasonal trees. It features a spacious deck with railings, large arched windows, and an American flag. A gentle pathway leads to the entrance, enhancing the inviting appearance of the property.
Home in Hot Springs
4.97 out of 5 average rating, 297 reviews

Bayou Lake House on Lake Hamilton

Come play on the lake or just relax and enjoy the view with a beautiful sunset in this spacious Lake Hamilton home. The house is conveniently located to everything Hot Springs has to offer. Shopping, dining, Oaklawn Racing, and historic downtown are all less than 10 minutes away. This three-bedroom home is fully furnished and has all the amenities. We don’t charge if you bring your pet, but we ask that you only bring up to two pets. Please note that parties/large gatherings are not allowed.

Top guest favorite
The treehouse sits elevated among trees, showcasing a spacious deck with circular windows. Leaves and twigs cover the ground, while a gentle stream flows nearby. A hammock is visible, inviting relaxation within the serene natural landscape.
Home in Fayetteville
5.0 out of 5 average rating, 338 reviews

A Luxury Treehouse Experience | Wood-Fired Cedar Hot Tub

Welcome to Whitetail & Pine, a Luxury Treehouse Experience. Nestled in the branches of two centuries old red oak trees and suspended 25 feet above Goose Creek, this arboreal abode offers a unique twist on traditional lodging. If you are seeking a rejuvenating getaway accented with the sights and sounds of nature, yet desire to be close to Fayetteville’s best restaurants and attractions, look no further than the Treehouse @ Whitetail & Pine. If you are on the fence, check out our reviews!

Top guest favorite
A screened-in porch features two woven armchairs positioned around a small table. The view highlights a serene landscape with a lake and mountains in the distance, bathed in the warm colors of sunrise. A colorful rug adds a cozy touch underfoot.
Home in Mountainburg
4.95 out of 5 average rating, 151 reviews

Locust Mountain View

This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!

Top guest favorite
Home in Dittmer
4.96 out of 5 average rating, 642 reviews

Honeymoon Suite at Camp Skullbone In The Woods

Experience a romantic, quiet, and cozy chalet designed for two! This charming retreat features vintage décor and all the modern amenities you need for a comfortable stay. Unwind indoors by kicking back and watching a movie, surfing the web, curling up with a good book or a friendly board game, or sharing a drink with that special someone. In the evening, relax on the cozy deck under the stars, basking in the warm glow of the gas fire pit or unwinding in the inviting private hot tub!

Top guest favorite
The exterior of the house features a covered entrance with a light brown door and large windows, allowing natural light into the interior. A concrete walkway leads to the door, flanked by a grassy lawn and neatly manicured shrubs.
Home in Golden
4.98 out of 5 average rating, 259 reviews

The Nut House on Table Rock Emerald Beach Lakeview

The Nut House sits on a 200 foot bluff overlooking Table Rock Lake. We are part of the Emerald Beach community which is mostly retirees. The best part of this 3 BR 2 BA home is the 900+ SF deck. There is a charcoal BBQ grill, dining tables/chairs, and comfy lounge chairs on the deck for summer; for winter, an easy-to-light fire pit (wood included). Lake access/boat ramp is 1/4 mile down this street. Feel free to swim there. You may see deer, fox, and bald eagles in the area.

Top guest favorite
Two blue mugs are placed on a glass-topped table overlooking the serene lake. The calm water reflects the surrounding tree-covered hills, creating a peaceful setting. Soft morning light illuminates the scene, enhancing the tranquil atmosphere of this lakeside retreat.
Home in Edwards
4.96 out of 5 average rating, 303 reviews

Rippling Point Lakefront House

Secluded at the end of a private drive on the quiet end of the Lake of the Ozarks, our lake home offers recreation, relaxation, and fishing opportunities. The house is on the water at the 67MM of the lake and features 300 feet of private shoreline. A deck that overhangs the water is just a few steps from a patio equipped with a propane/charcoal grill and outdoor cooking area. Two kayaks are included to explore the shoreline and its wildlife. An inviting hot tub beckons.

Guest favorite
A private in-ground saltwater pool features a smooth deck surrounded by lounge chairs. Two outdoor gazebos provide shaded seating, while four round tables, each with four chairs and umbrellas, offer additional gathering spaces. Lush greenery from nature surrounds the area.
Home in Joplin
4.89 out of 5 average rating, 106 reviews

Pool/Hot tub/ game room

POOL IS OPEN!! Relax at this peaceful, charming 2-bedroom, 1-bath home. Which also includes an arcade/game room. It sits on a beautiful, wooded acre where deer roam freely and nature surrounds you. It’s the perfect place to relax, recharge, and enjoy a slower pace—without leaving the city behind. Grill while you unwind on the flagstone patio, then cool off in your private in-ground salt water pool. In the mornings, grab a coffee and watch deer wander through the yard.

Guest favorite
A fire pit is surrounded by several dark blue Adirondack chairs, set on a paved area next to the river. The moonlight reflects off the water, creating a serene ambiance, while a large tree provides shade in the background.
Home in Jefferson City
4.97 out of 5 average rating, 122 reviews

Rivers Edge Retreat

Welcome to Rivers Edge Retreat – Your Serene Escape on the Osage River Nestled on the tranquil banks of the Osage River in Jefferson City, Missouri, Rivers Edge Retreat offers an idyllic escape from the hustle and bustle of everyday life. Our cozy and charming retreat boasts breathtaking views, a peaceful atmosphere, and all the comforts of home, making it the perfect destination for relaxation and adventure.

Popular amenities for Mississippi River house rentals

Destinations to explore