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Boutique hotels in Mississippi River

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Mississippi River

Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

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Top guest favorite
A handmade ceramic mug featuring the McFarland House logo is placed next to a small vase of lilacs. A muffin in a paper liner rests on a white plate, with the dark wood table providing a contrasting background.
Hotel room in McFarland
4.96 out of 5 average rating, 180 reviews

302 Edward's Attic Suite - Queen Bed

Edward's attic suite pays tribute to early local families who quietly shaped the town's development through business, farming, and civic leadership. Tucked into the upper level of the home, this suite embraces its architectural charm with angled ceilings, cozy corners, and warm textures that feel intimate yet elevated. Queen bed Full kitchen Comfy living room Original flooring Boutique finishes Perfect for quests who value privacy, charm, and the feeling of having discovered something special.

Guest favorite
A spacious room features large windows overlooking Beaver Lake, allowing natural light to fill the space. A cozy sitting area includes a beige sofa and a rustic coffee table, while a queen pillow-top bed is positioned nearby. Accent walls of natural stone add texture to the room.
Hotel room in Eureka Springs
4.95 out of 5 average rating, 277 reviews

Romantic Lake View Jacuzzi Suite

Jacuzzi Suites are the size of a hotel room with the privacy of a woodsy cabin. Our suites the perfect way to spend a romantic getaway. Each suite has a queen pillow-top bed, a sitting area, a Jacuzzi for two and a small deck with a stunning view of Beaver Lake. No kitchens; however, each one has a coffee bar w/ mini fridge, microwave and Keurig. Each suite has its own private boardwalk entrance to ensure privacy. We have 3 suites attached to the office building. No pets allowed in the suites.

Top guest favorite
A spacious room features antique stone walls and hardwood flooring. A large wooden bed is flanked by two lamps, with decorative pillows adding color. A seated area includes a soft chair, and a dresser complements the warm, inviting decor.
Hotel room in Eureka Springs
4.99 out of 5 average rating, 318 reviews

Downtown luxury suite, privacy and convenience!

Relax in a spacious, private suite that allows you to stretch. The Anderson Suite at Twilight Terrace offers 800 gorgeous square feet. Feel right at home with the great Arts and Crafts décor, a kitchenette with fridge and microwave, Wifi and a flat screen TV with cable. The bath boasts a jet tub for 2 and a tiled shower for 2. Antique accents with modern amenities give you a comfortable, luxurious base to enjoy Eureka Springs! Add in OFF-STREET PARKING and you’re set for a fabulous stay!

Guest favorite
The elegant Grand Manor is set against a vibrant sunset, surrounded by tall palm trees. The two-story structure showcases a classic southern architectural style with a grand entrance, adorned with decorative lighting along the pathway and lush greenery enhancing the inviting exterior.
Hotel room in Galveston
4.87 out of 5 average rating, 639 reviews

Garden Lace Suite- Grand Manor Boutique Hotel

The elegant Grand Manor (3.5 blks to cruise) Built 1905, a true southern tropical mansion. Luxury amenities seamlessly blended with Victorian grace (6 other rooms avail) Located in Galveston's East End Historic District , considered one of the top architectural structures on the Island Guest rooms are richly appointed, with king size beds. Private baths are soaker or claw-footed tubs. Best walking location to Island Funky bars & rooftop patios,harbor minutes to WORLD FAMOUS STRAND

Top guest favorite
The room features a queen size bed adorned with a decorative red and gold coverlet. Two windows are dressed with plush maroon curtains. A dresser with a mirror and a TV are positioned against one wall, while a faux fireplace adds warmth to the inviting space.
Hotel room in Osceola
4.93 out of 5 average rating, 117 reviews

Historic Commercial Hotel(1868),Sally Rand Suite

The Historic Commercial Hotel (Est.1868) on the Downtown square in beautiful Osceola,Missouri. Old world feel with modernized accommodations. The Historic Commercial Hotel has numerous themed rooms which are designed and named after past historical guests. This specific room is "The Sally Rand Suite". Named after past historical guest Sally Rand ( 1904 – 1979) who was an American burlesque dancer and Silver Screen star, most noted for her ostrich feather fan dance and balloon bubble dance.

Guest favorite
Hotel room in Pacific
4.84 out of 5 average rating, 110 reviews

Queen room for two near wedding venues

Pilot 1 Room • Located on the second floor, this room is a more affordable option compared to our other rooms. • Features a queen bed and a half bath en suite. • Guests share 2 shower rooms located just outside the room with the 3 other Pilot rooms. • Includes a TV and desk in the room. Additional Amenities • Large community space on the first floor with a kitchen and activities. • Seasonal pool access. Other Rooms • Two Captain rooms on the first floor each have a full private bathroom.

Top guest favorite
The room features exposed brick walls and a wooden ceiling, enhancing the rustic charm. A spacious bed sits beside a cozy seating area with an orange armchair and a guitar. Natural light floods in through multiple large windows, with decorative elements like a cowhide rug and artwork adding character.
Hotel room in Hannibal
4.97 out of 5 average rating, 158 reviews

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

Top guest favorite
A charming living area features a vibrant blue fireplace surrounded by decorative accents. A wooden coffee table rests on a cowhide rug, complemented by a brown leather couch. Colorful wall art and mirrors enhance the space, while a front door with stained glass adds character.
Hotel room in Eureka Springs
4.95 out of 5 average rating, 281 reviews

Clean, Eclectic, Private stay in Historic Loop

We offer a uniquely Eurekan experience on the upper loop of the Historic District. We are within walking distance to shopping, dining, and entertainment and right next to the trolly stop for those who prefer to ride! Enjoy two bath options with our oversized Jacuzzi tub or old-school claw-foot tub/shower! You will have a designated parking spot off the street and a private patio to people watch as you sip coffee, tea or a nightcap of your choice.

Top guest favorite
A modern kitchen area features sleek stainless steel appliances, including a refrigerator and an oven. A wooden dining bar with stools provides seating. A television mounted on the wall is complemented by a small console table with a decorative lamp. A large wall clock adds a stylish touch.
Hotel room in Evansville
4.96 out of 5 average rating, 119 reviews

Theodore Robinson Suite-Grove Guest House

The Grove Guest House provides an exceptional lodging experience while working in the area or spending vacation time in the newly opened historic downtown boutique hotel. The Theodore Robinson Suite is fully equipped with all amenities for a single night stay or an extended visit. Internet service and smart TVs in both sitting area and bedroom. The Suite has bedroom with a king bed, private bath and full kitchen and laundry.

Guest favorite
The spacious room features sloped ceilings and large windows that allow natural light to fill the space. A queen bed draped in a soft coverlet is positioned beside a modern in-room jacuzzi tub. Dark countertops contrast with the light walls, creating a serene atmosphere.
Hotel room in Branson
4.82 out of 5 average rating, 206 reviews

Lavender Paradise: Room #26 at The Bradford

Come enjoy a relaxing stay at The Bradford! Easy access to the Branson Strip and only 5 minutes from Silver Dollar City! Our rooms are newly remodeled, and each have their own uniqueness. The complimentary coffee bar and game room are everything you need before a fun-filled day in Branson! There’s no other view of the Branson strip quite like The Bradford’s! You won’t want to leave this charming, one-of-a-kind property.

Top guest favorite
Hotel room in Galveston
4.97 out of 5 average rating, 410 reviews

Clawfoot Tub Suite | Walk Downtown

A romantic private suite with a freestanding vintage clawfoot tub inside the room plus a separate en-suite bathroom with a toilet and sink. This Victorian era room features 12 foot ceilings, bay windows, blackout shades and an antique poster bed with a plush queen mattress from Silk & Snow. Thoughtfully designed with vintage details and modern comfort for a unique and relaxing stay.

Guest favorite
A row of charming dome accommodations is set against a backdrop of greenery, showcasing distinctive round structures with white exteriors. Each unit features a clearly marked entrance and large windows that allow natural light to fill the interior. A well-maintained pathway leads visitors to the suites.
Hotel room in Bellville
4.98 out of 5 average rating, 107 reviews

Country Dome Suites

Each spacious suite is a beautiful combination of country, modern, and industrial décor. Your fully furnished suite contains a sleeping area, kitchen, and bathroom with 26 sq. ft. walk-in shower. Every suite has a complimentary hot drinks bar with coffee and tea. Come and stay, and then come again as you ESCAPE busy and REVEL in simple at Country Dome Suites.

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