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Guesthouse vacation rentals in Mississippi River

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Mississippi River

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite
An open-concept living space features a well-equipped kitchen with stainless steel appliances and wooden cabinetry. A large dining table is positioned nearby, complemented by a comfortable seating area with a sofa and armchair. Rustic beams enhance the airy atmosphere of the room.
Guesthouse in Hermann

The Downtown Hermann Hen House Food/Bar/Music/Fun

Free Buffet Breakfast/Free Drink Tickets/Live Music Nightly through Oct./Personalized $20 Per Person Shuttle (Trolley is $30)1837 Bar/Restaurant. Put All Your Eggs in the Hen House’s Basket. Right by Restaurants/Shopping/Bars. 2 Bedrooms, 2 Private Bathrooms, & 2 Queen Pullout Sleepers in Living Room. Room for 8 Guests. Full Kitchen & Large Farm Table for Dining or Games with Your Friends. Property Managed by the Hermann Crown Suites next door. Call Hermann Crown to Reserve Spot on Shuttle Now.

FamilyLocationCheckout

4.95 out of 5 average rating, 147 reviews
Top guest favorite
A spacious sleeping area features a queen-size bed dressed in a turquoise coverlet, complemented by decorative pillows. Natural light floods through a nearby window covered with light curtains. A wooden dresser and bedside table add warmth to the room, while framed artwork enhances the decor.
Guesthouse in Shawnee Mission

Westwood cottage in garden setting

This 400 sq. ft. guesthouse (studio) on a historic property in Westwood, KS has recently been fully renovated and furnished. It has a completely equipped kitchenette, comfortable living area, along with a queen-size bed. The guesthouse also includes a washer/dryer off the kitchenette. The guesthouse is a separate dwelling located on a half an acre property which includes the original farmhouse built in 1889 - the guesthouse added in 1920. Westwood, Kansas is 2 miles from the Country Club Plaza.

LocationFamilyQuiet

4.99 out of 5 average rating, 728 reviews
Top guest favorite
Guesthouse in Bella Vista

Women of the Woods • Where the Forest Finds You

Step inside and feel the outside disappear. This beautifully curated woodland retreat is tucked into the trees of Bella Vista with a woodsy backyard that opens directly onto the Back 40. Guests consistently remark on attentiveness of hosts, cleanliness, and thoughtful touches. Close enough to everything when you're ready for it, Downtown Bentonville is 20 minutes away. Crystal Bridges, world-class mountain biking, scenic hiking, lakes, shopping, restaurants, and golf are all within easy reach.

LocationValueComfort

5.0 out of 5 average rating, 121 reviews
Top guest favorite
A serene landscape features several horses grazing in a lush green pasture. The expansive grassy area is bordered by a wooden fence and trees in the background, creating a peaceful rural setting.
Guesthouse in Wright City

Red Mule Ranch - Breakfast included

Cozy, rustic, “bunkhouse." Charming cedar log double bed. Private bath. Located on 85 acre horse farm. Lrg pond, beautiful pastures. Near Innsbrook, Cedar Lakes Cellars Winery, Big Joel's Safari, Long Row Lavender Farm, and many local wineries & antique shops. Homemade breakfast (5 choices), at NO extra charge, & chocolate chip cookies are in your room upon arrival. Perfect anniversary getaway. Your favorite pie/ cake can be made for a small charge. NO cleaning fees #1 Airbnb Host in Missouri

FamilyValueDecor

5.0 out of 5 average rating, 290 reviews
Top guest favorite
The exterior of a brick guesthouse cottage is presented, featuring a pointed roof and tall, arched windows. Lush greenery surrounds the entrance, which has a wooden door framed by two lanterns. Stone steps lead up to the front door, enhancing the inviting appearance.
Guesthouse in Bentonville

Cozy Cottage on C

Welcome to our structural masonry guesthouse cottage in the heart of Downtown Bentonville. You'll feel like you're stepping back in time into a historic building made entirely out of brick, but our backyard cottage was completed in 2023 as a labor of love and hospitality. Enjoy direct access to Park Springs Park and trails at the end of the block, or a short walk/ride to the Downtown square. We live in the main house on the property, but designed the cottage to maximize guest privacy. Welcome!

ValueLocationCheck-in

4.98 out of 5 average rating, 392 reviews
Top guest favorite
A tranquil outdoor space is presented with two Adirondack chairs positioned next to a stone fire pit. A pathway leads to a modern wooden loft elevated above the ground, surrounded by trees and a neatly stacked pile of firewood.
Guesthouse in Hasty

The Loft - Mt. Views & Close River Access (0.7)

Created just for two, this cozy haven is the perfect base camp for your outdoor adventures. The Loft features gorgeous mountain views and quick access to the Buffalo River. This 352 square foot modern studio boasts an exceptional outdoor living space. Sit on the porch with your morning coffee before you head out for adventure and keep an eye out for the deer that feel right at home on our 40 acre property. PLEASE SEE the “Other details to note “ section regarding proximity to the main house.

LocationValueCondition

4.99 out of 5 average rating, 163 reviews
Top guest favorite
A modern bathroom features a fully tiled shower with a large rain shower head. A sleek granite countertop with a sink and a towel shelf complements the space. Decorative plants add a natural touch against the white tiled walls.
Guesthouse in Cave Springs

Rustic digs on acreage Near Mt Hebron Park, Rogers

Peaceful location, Located near the Pinnacle shopping area, Walmart AMP, Osage house and XNA airport. Space does not share any walls with other living spaces. It is located in our shop building. Fully tiled shower with a large rain shower head. Main room includes a sink, refrigerator, microwave and the essentials to prepare simple meals. Room dimensions are 15x12 plus small bathroom. Bicycles can be available, ask in advance. Only registered guests are allowed in the pool and hot tub.

ValueFamilyLong stay

4.96 out of 5 average rating, 310 reviews
Guest favorite
The octagonal cottage is surrounded by a well-manicured lawn and features a stepping stone pathway leading to a patio area. Large windows with shutters offer natural light, and a small air conditioning unit is visible on the side of the structure.
Guesthouse in Eudora

Cozy cottage getaway in garden paradise

Get away and relax in a whimsical octagonal cottage surrounded by a lush garden, overlooking a aqua pond and the Wakarusa river. You will have everything you need for a romantic date night or an inspiring place to slow down and reconnect with nature. •1 bedroom open living space with lots of natural light and beautiful views. • Coffee cart with microwave and electric burner and mini frig are provided. • Paddle boat at the lower pond & 2 disc golf nets available for fun. •NO PETS ALLOWED

ValueFamilyAccess

4.89 out of 5 average rating, 267 reviews
Top guest favorite
A screened porch features a round table surrounded by four chairs, all with green cushions. Natural light streams through the screens, showcasing views of a tranquil lake framed by colorful autumn foliage.
Guesthouse in Berwick

Private Guest Lake House On 37 Acres In Country

Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

ValueFamilyBackyard

4.99 out of 5 average rating, 268 reviews
Guest favorite
A small farmhouse with a metal roof is set in a grassy area, featuring a covered porch with several dark chairs. Large glass doors provide access to the interior, while a nearby shed stands in the background under a partially cloudy sky.
Guesthouse in Fordland

Panther Creek Guesthouse

Small farmhouse, private fenced and gated yard, on a tiny farm on a gravel road. Host next door has dwarf goats, chickens, ducks, guineas (1 pair regularly visits/patrols the guesthouse yard), turkeys, a goose, and a couple of LGDs. Horses live across the road and around the curve and up the hill. Eggs and some other basic food items included! Less than 5 miles off Hwy 60 north of Fordland Café, Dollar General, gas in Fordland Springfield 24 Branson 55 7.5 miles from I-44 @ Northview

LocationFamilyParking

4.92 out of 5 average rating, 216 reviews
Top guest favorite
A spacious living area features a comfortable sofa facing a fireplace and a wall-mounted television. Natural light floods the space through large windows, providing views of the deck and surrounding greenery. A dining table for six is positioned nearby, complemented by a woven light fixture.
Guesthouse in Blue Eye

Turtle Cove- Hot tub, Kayaks, Fire Wood Included

Come and enjoy a peaceful getaway in our quiet cove on Table Rock Lake. Relax in our guest house with a private deck, hot tub, outdoor shower, fire pit and beach at your back door! Enjoy swimming or fishing in the cove, sunning on a paddle board or kayaking at sunset. Paddle boards and kayaks included! Welcome family time relaxing on the hammock listening to the water lapping, barbecuing on the deck or chilling by the fire pit (firewood included). Come rejuvenate in nature's beauty!!

LocationValueBeach

4.97 out of 5 average rating, 305 reviews
Top guest favorite
A modern living space features a gray sectional sofa adorned with patterned throw pillows. A round coffee table sits in front, surrounded by decorative accessories. Tall windows allow natural light to fill the room, complemented by a textured area rug and a tall plant for added warmth.
Guesthouse in Rogers

The Penthouse in DTR

Enjoy a stay at the only Luxury apartment rental conveniently located just two blocks from downtown Rogers. The Penthouse in Downtown Rogers is a modern and stylish apartment with all the amenities you need for a short stay or a long retreat: sumptious Sleep Number bed and bedding, gourmet kitchen and outdoor barbecue area, luxe shower and outdoor hot tub with an outdoor fire pit to boot. Just 3 blocks from the Railyard mountain bike park, a short trail to lake Atalanta park.

LocationFamilyHospitality

4.98 out of 5 average rating, 370 reviews

Popular amenities for Mississippi River guesthouse rentals

KitchenWifiPoolFree parking on premisesAir conditioning

Family-friendly guest house rentals

Top guest favorite
A serene landscape is captured with tall trees casting long shadows over a lush green lawn. Sunlight filters through the branches, illuminating the space and creating a calming outdoor atmosphere.
Guesthouse in Tahlequah

Serene setting w/ private Illinois River access

FamilyLocationCleanliness

4.89 out of 5 average rating, 121 reviews
Top guest favorite
A welcoming entrance features a blue door framed by decorative pillars. A gravel path leads to the door, bordered by a vibrant flower garden with colorful blooms. Swing chairs provide seating on either side, creating an inviting atmosphere for guests.
Guesthouse in Roach

Quiet Cottage

FamilyLocationSleep quality

4.96 out of 5 average rating, 405 reviews
Guest favorite
A cozy cabin overlooks a tranquil lake, surrounded by lush greenery. A wooden deck leads to an inviting seating area with several white chairs arranged in a semi-circle around a campfire pit. Large windows with red trim add character to the structure.
Guesthouse in Elkhorn

Camp Wandawega: Lakeside 3 Bedroom Cabin

FamilyValueSleep quality

4.98 out of 5 average rating, 183 reviews
Top guest favorite
The entrance to a small shed is framed by a wooden fence, featuring a bright yellow door. Decorative tools and vintage items are mounted on the fence, enhancing the shed's unique character. The ground is covered with wood chips and surrounded by a small garden of flowers.
Guesthouse in Rogers

Rustic tool shed stay unique tiny home experience

FamilyValueParking

4.96 out of 5 average rating, 1091 reviews
Guest favorite
The historic lodging is situated amidst tall grass, with a solitary tree in the foreground. The building's exterior is softly illuminated by windows, highlighting its long, linear shape against the twilight sky.
Guesthouse in Matfield Green

Matfield Station - #3 North Unit

FamilyLocationComfort

4.97 out of 5 average rating, 138 reviews
Top guest favorite
A covered outdoor seating area features a glass table surrounded by four chairs. In the background, a calm water body reflects the greenery of trees lining the shore, providing a serene setting for relaxation.
Guesthouse in Cherokee

Bunkhouse on the Water

LocationFamilyIndoor spaces

5.0 out of 5 average rating, 162 reviews
Guest favorite
A spacious guest room is highlighted by a queen bed dressed in warm-toned linens. Natural light filters through large windows adorned with sheer curtains. A cozy seating area includes a sofa and a round coffee table. A decorative fireplace and small dining set add to the inviting decor.
Guesthouse in Owasso

French Woods Quarters

LocationValueBackyard

4.88 out of 5 average rating, 319 reviews
Top guest favorite
A serene view of the cottage is presented alongside a natural swimming pond-pool, surrounded by lush greenery and landscaping. A spacious deck is visible adjacent to the pond, with a pergola providing shaded seating nearby, framed by areas of well-maintained lawn.
Guesthouse in Jonesboro

Clearly Hidden Acres Cottage and Farm

LocationFamilyCheck-in

4.98 out of 5 average rating, 348 reviews

Guest house rentals with a patio

Top guest favorite
The treehouse structure features a balcony with wooden railings, surrounded by lush trees. A long wooden dining table is positioned on the patio underneath, adorned with vibrant flower planters. Flags flutter gently in the breeze, enhancing the outdoor space's welcoming ambiance.
Guesthouse in Caddo Valley

Ouachita River Treehouse

LocationFamilyHospitality

4.98 out of 5 average rating, 176 reviews
Top guest favorite
The living area features a charming combination of white cabinetry and soft furnishings, complemented by a stone fireplace and large windows allowing natural light. A dining table is set for six, and decorative floral arrangements add a touch of color throughout the space.
Guesthouse in Jenks

The Rose Cottage w/ Gardens & easy access to Tulsa

LocationFamilyQuiet

4.96 out of 5 average rating, 105 reviews
Top guest favorite
A modern kitchen and dining area features sleek appliances and ample countertop space. A wooden dining table with woven chairs accommodates six. Pendant lights hang above the kitchen island, and large windows allow natural light to fill the space, creating a bright and welcoming atmosphere.
Guesthouse in Mountain Home

My Sweet Mtn. Home - Guest House with Hot Tub!

ValueFamilyOutdoor spaces

4.95 out of 5 average rating, 122 reviews
Top guest favorite
A cozy bedroom features a large wooden bed dressed in soft linens, flanked by bedside lamps. A patterned area rug enhances the space, while elegant furniture adds character. Natural light filters in through a window, creating a soothing ambiance.
Guesthouse in Siloam Springs

Charming Stone Cottage - Quiet Central Location

FamilyLocationSleep quality

4.99 out of 5 average rating, 150 reviews
Top guest favorite
The cabin features a wooden exterior surrounded by greenery, positioned on a gently sloping hillside. A spacious deck with a railing overlooks the landscape, with stone steps leading up to it. Colorful flowers add natural beauty along the pathway to the entrance.
Guesthouse in Ozark

Unique Cabin in the Mulberry River Valley

LocationFamilyKitchen

5.0 out of 5 average rating, 108 reviews
Top guest favorite
A cozy cabin is nestled among tall trees, featuring a welcoming front porch and a green door. The surrounding lawn is well-kept, with open fields visible in the distance, creating a peaceful and serene setting.
Guesthouse in Jerseyville

Cozy cabin on farm near Jerseyville and Grafton IL

FamilyLocationRiver

4.96 out of 5 average rating, 202 reviews
Superhost
An open kitchen and living area features natural clay tile flooring. A dining table for two is positioned beside the kitchen island with seating for three. A cozy seating area with a vibrant green sofa is visible, complemented by decorative plants and artwork on the walls.
Guesthouse in Fayetteville

Earthen Oasis - Nature Retreat Minutes to Downtown

ValueLocationAir conditioning

4.93 out of 5 average rating, 142 reviews
Guest favorite
A cozy seating area is featured with a floral patterned loveseat and a blue checked armchair, complemented by a decorative pillow. Two windows framed with plaid curtains allow natural light to fill the space, while wooden flooring adds warmth to the room.
Guesthouse in Rolla

Charming Hummingbird Cottage

LocationValueAccuracy

4.96 out of 5 average rating, 114 reviews

Guest house rentals with a washer and dryer

Top guest favorite
An aerial view reveals a shared outdoor pool surrounded by a concrete patio, adorned with lounge chairs and shaded areas. A charming guesthouse is visible nearby, complemented by a flagpole featuring an American flag, all set within a spacious green landscape.
Guesthouse in Shawnee

1 of a Kind Guesthouse on 4 Acres. Dogs allowed

FamilyValuePets

5.0 out of 5 average rating, 259 reviews
Top guest favorite
A charming red cottage is nestled among tall trees, showcasing a welcoming front with two white Adirondack chairs placed on a natural surface. Decorative flower arrangements hang near the entrance, surrounded by lush greenery and plants.
Guesthouse in Ashland

Norrsken Scandinavian Cottage

ValueLocationWalkability

4.99 out of 5 average rating, 423 reviews
Top guest favorite
A modern shop home stands surrounded by lush greenery, featuring a covered porch with two chairs positioned at the entrance. The building has a sleek metal exterior, complemented by a spacious yard that invites relaxation.
Guesthouse in Bentonville

The Little Shop House

FamilyValueHiking

4.94 out of 5 average rating, 125 reviews
Top guest favorite
A serene outdoor area showcases a grassy landscape bordered by several trees. The setting is peaceful, with a gentle incline leading towards more trees in the distance, offering a natural and relaxing environment.
Guesthouse in Flippin

Lafon's Flippin Cottage

ValueFamilyQuiet

5.0 out of 5 average rating, 102 reviews
Top guest favorite
Guesthouse in Ottawa

The Hangar

LocationFamilyOutdoor spaces

4.96 out of 5 average rating, 117 reviews
Top guest favorite
The kitchen features a large island with seating for four, complemented by pendant lights. A modern stove is positioned beneath a wooden hood. Gray cabinetry lines the walls, with white tile backsplash adding brightness. Appliances, including a refrigerator and coffee maker, are also present.
Guesthouse in Nixa

Harvest Hill Hideaway

FamilyLocationBiking

4.97 out of 5 average rating, 344 reviews
Top guest favorite
A canoe is positioned on still waters, surrounded by dense fog that creates a serene atmosphere. The seat is adorned with a blanket featuring a red cross design, adding a touch of color amidst the muted landscape. Tree silhouettes emerge faintly in the background.
Guesthouse in Monroe

Bayou Long Beard - Bayou view! We greet everyone!

LocationValueShared spaces

5.0 out of 5 average rating, 353 reviews
Top guest favorite
The guesthouse interior features an open layout with a queen bed adorned in soft linens next to a sleek nightstand. A cozy sofa and a circular dining table with four chairs complement the space, with natural light filtering through the windowed doors.
Guesthouse in Webb City

Bright and Modern Private Guesthouse near Route 66

LocationValueQuiet

4.97 out of 5 average rating, 719 reviews

Destinations to explore