
Guesthouse vacation rentals in Mississippi River
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Top-rated guesthouse rentals in Mississippi River
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Westwood cottage in garden setting
This 400 sq. ft. guesthouse (studio) on a historic property in Westwood, KS has recently been fully renovated and furnished. It has a completely equipped kitchenette, comfortable living area, along with a queen-size bed. The guesthouse also includes a washer/dryer off the kitchenette. The guesthouse is a separate dwelling located on a half an acre property which includes the original farmhouse built in 1889 - the guesthouse added in 1920. Westwood, Kansas is 2 miles from the Country Club Plaza.
4.99 out of 5 average rating, 726 reviews
The Downtown Hermann Hen House Food/Bar/Music/Fun
Free Buffet Breakfast/Free Drink Tickets/Live Music Nightly through Oct./Personalized $20 Per Person Shuttle (Trolley is $30)1837 Bar/Restaurant. Put All Your Eggs in the Hen House’s Basket. Right by Restaurants/Shopping/Bars. 2 Bedrooms, 2 Private Bathrooms, & 2 Queen Pullout Sleepers in Living Room. Room for 8 Guests. Full Kitchen & Large Farm Table for Dining or Games with Your Friends. Property Managed by the Hermann Crown Suites next door. Call Hermann Crown to Reserve Spot on Shuttle Now.
4.94 out of 5 average rating, 145 reviews
Women of the Woods • Where the Forest Finds You
Step inside and feel the outside disappear. This beautifully curated woodland retreat is tucked into the trees of Bella Vista with a woodsy backyard that opens directly onto the Back 40. Guests consistently remark on attentiveness of hosts, cleanliness, and thoughtful touches. Close enough to everything when you're ready for it, Downtown Bentonville is 20 minutes away. Crystal Bridges, world-class mountain biking, scenic hiking, lakes, shopping, restaurants, and golf are all within easy reach.
5.0 out of 5 average rating, 120 reviews
Cozy Cottage on C
Welcome to our structural masonry guesthouse cottage in the heart of Downtown Bentonville. You'll feel like you're stepping back in time into a historic building made entirely out of brick, but our backyard cottage was completed in 2023 as a labor of love and hospitality. Enjoy direct access to Park Springs Park and trails at the end of the block, or a short walk/ride to the Downtown square. We live in the main house on the property, but designed the cottage to maximize guest privacy. Welcome!
4.98 out of 5 average rating, 390 reviews
The Loft - Mt. Views & Close River Access (0.7)
Created just for two, this cozy haven is the perfect base camp for your outdoor adventures. The Loft features gorgeous mountain views and quick access to the Buffalo River. This 352 square foot modern studio boasts an exceptional outdoor living space. Sit on the porch with your morning coffee before you head out for adventure and keep an eye out for the deer that feel right at home on our 40 acre property. PLEASE SEE the “Other details to note “ section regarding proximity to the main house.
4.99 out of 5 average rating, 162 reviews
Private Guest Lake House On 37 Acres In Country
Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.
4.99 out of 5 average rating, 267 reviews
Serene setting w/ private Illinois River access
Come relax with the family! This one bedroom guest house is just a stones throw from private access to the Illinois river. Located 15 minutes from Tahlequah and 10 minutes from local float venues. Come and enjoy a peaceful and quiet stay at the foothills of the Ozarks. Bring Your Own Float Devices and enjoy floating down to Todd Landing public access point, which is about an hour long adventure. Relax on the deck while enjoying the local wildlife! Bald eagles and deer frequent the area.
4.89 out of 5 average rating, 121 reviews
Turtle Cove- Hot tub, Kayaks, Fire Wood Included
Come and enjoy a peaceful getaway in our quiet cove on Table Rock Lake. Relax in our guest house with a private deck, hot tub, outdoor shower, fire pit and beach at your back door! Enjoy swimming or fishing in the cove, sunning on a paddle board or kayaking at sunset. Paddle boards and kayaks included! Welcome family time relaxing on the hammock listening to the water lapping, barbecuing on the deck or chilling by the fire pit (firewood included). Come rejuvenate in nature's beauty!!
4.97 out of 5 average rating, 303 reviews
The Penthouse in DTR
Enjoy a stay at the only Luxury apartment rental conveniently located just two blocks from downtown Rogers. The Penthouse in Downtown Rogers is a modern and stylish apartment with all the amenities you need for a short stay or a long retreat: sumptious Sleep Number bed and bedding, gourmet kitchen and outdoor barbecue area, luxe shower and outdoor hot tub with an outdoor fire pit to boot. Just 3 blocks from the Railyard mountain bike park, a short trail to lake Atalanta park.
4.98 out of 5 average rating, 370 reviews
Relax in Architecture! Secluded, Safe, and Serene.
Welcome to the Falk House! Listed on the National Register of Historic Places by the US Department of the Interior, the Falk House is a treasure of mid-century modern design. We've transformed the original art studio into a stylish, private oasis, with expansive views of nature and Eastover’s Upper Twin Lake. You will be central to all metro destinations, including amazing restaurants, bars, and shopping, as well as area hospitals, courts, and businesses. Long stays ideal.
4.98 out of 5 average rating, 167 reviews
Tanyard Creek | Waterfall · Bike In/Out
Walk to the waterfall. Ride to the trails. Relax in the trees. Set directly above Tanyard Creek, this private guesthouse offers immediate access to scenic hiking paths and nearby MTB trails—making it the perfect basecamp for both riders and nature-focused stays. Designed for those who want to be outside during the day and fully recharge at night, the space is dialed for comfort with Tempur-Pedic beds and a specialty coffee setup to start your mornings right.
4.94 out of 5 average rating, 156 reviews
Bunkhouse on the Water
The Bunkhouse sits adjacent to a large body of water. Just 10 miles to Pittsburg and 30 miles to Joplin, MO. Guests can enjoy time outside on the covered porch next to the water, sit around the fire pit on those cool evenings, or enjoy some catch and release fishing from the bank. Experience country living and sights and sounds of nature. Free range chickens also roam the property. 3 GUESTS MAX NO OUTSIDE GUESTS
5.0 out of 5 average rating, 162 reviewsPopular amenities for Mississippi River guesthouse rentals
Family-friendly guest house rentals

Camp Wandawega: Lakeside 3 Bedroom Cabin
4.98 out of 5 average rating, 183 reviews
Quiet Cottage
4.96 out of 5 average rating, 405 reviews
Red Mule Ranch - Breakfast included
5.0 out of 5 average rating, 290 reviews
Hickman cabin
4.96 out of 5 average rating, 407 reviews
tiny guest house pool 2 bed / Fire-pit
4.9 out of 5 average rating, 216 reviews
French Woods Quarters
4.88 out of 5 average rating, 318 reviews
Clearly Hidden Acres Cottage and Farm
4.98 out of 5 average rating, 348 reviews
Rustic tool shed stay unique tiny home experience
4.96 out of 5 average rating, 1089 reviewsGuest house rentals with a patio

Cozy cottage getaway in garden paradise
4.89 out of 5 average rating, 267 reviews
Ouachita River Treehouse
4.98 out of 5 average rating, 175 reviews
Unique Cabin in the Mulberry River Valley
5.0 out of 5 average rating, 108 reviews
My Sweet Mtn. Home - Guest House with Hot Tub!
4.95 out of 5 average rating, 122 reviews
The Rose Cottage w/ Gardens & easy access to Tulsa
4.96 out of 5 average rating, 105 reviews
Earthen Oasis - Nature Retreat Minutes to Downtown
4.93 out of 5 average rating, 141 reviews
Adorable 1 bedroom guest house
4.95 out of 5 average rating, 214 reviews
Charming Stone Cottage - Quiet Central Location
4.99 out of 5 average rating, 150 reviewsGuest house rentals with a washer and dryer

Panther Creek Guesthouse
4.92 out of 5 average rating, 216 reviews
1 of a Kind Guesthouse on 4 Acres. Dogs allowed
5.0 out of 5 average rating, 259 reviews
The Little Shop House
4.94 out of 5 average rating, 124 reviews
Coffee Cabin
4.99 out of 5 average rating, 113 reviews
Lafon's Flippin Cottage
5.0 out of 5 average rating, 102 reviews
Bayou Long Beard - Bayou view! We greet everyone!
5.0 out of 5 average rating, 353 reviews
SoMa Cottage with fenced yard & off st Parking
4.99 out of 5 average rating, 547 reviews
Norrsken Scandinavian Cottage
4.99 out of 5 average rating, 423 reviewsDestinations to explore
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