Vacation rentals in Mississippi River

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Top-rated vacation rentals in Mississippi River

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Cabin in Elizabeth
4.99 out of 5 average rating, 102 reviews

Secluded Lakefront Estate | Couples Retreat

Welcome to Sunset Cove on Norfork Lake, a secluded 60-acre gated lakefront estate where modern luxury meets untouched Ozark wilderness. Designed for couples seeking a rare escape where time slows, distractions fade, and world feels far. Mornings unfold slowly and evenings are peaceful, with sweeping lake views throughout the day. Spend your time exploring together between the water, hot tub, and quiet lakeside spaces in nature — a setting designed for stillness, connection, uninterrupted moments

Top guest favorite
A modern cabin exterior is framed by natural stone and gravel. Rock formations surround a central fire pit with burning flames. The structure features large windows and a covered porch with two rocking chairs, set against a backdrop of lush greenery and rising hills.
Cabin in Clayton
5 out of 5 average rating, 157 reviews

Romantic Private Luxury Getaway With Amazing Views

Welcome to Suite Serenity, a luxury cabin tucked away in the foothills of the Ouachita Mountains. The cabin has large picture windows to enjoy the stunning views of Sardis lake and surrounding mountains. Every room in the cabin has a great view. Sitting by the fire while watching the sun set is so relaxing. There are camp grounds and a boat dock across the street providing a great place for recreation. Sand volleyball, swim beach, pavilion & hiking trails are a few of the amenities. Come enjoy!

Top guest favorite
A rustic cabin exterior is framed by lush green grass and trees. The wooden structure features a stone chimney and a distinctive blue door, with two large windows on the left. A simple stone path leads to the entrance, inviting relaxation in a natural setting.
Cabin in Chanute
4.98 out of 5 average rating, 606 reviews

The Blue Door Cabin

If you want a retreat where you can sleep in, slow down and savor nature's beauty, the Blue Door Cabin, tucked in surprisingly hilly oak and hickory woods, with a beautiful view of the pond, is your destination. Within two hours from Kansas City, Tulsa, Joplin or Wichita, and only 4 miles from Chanute Kansas, this preserved and revived cabin offers an easy getaway for city dwellers in need of a very affordable anniversary weekend, study or solitude retreat, or family hiking and fishing trip.

Top guest favorite
A fire pit surrounded by several light-colored chairs sits on a grassy area. In the background, a single-story house is visible along with a covered porch and outdoor seating. Lush trees and greenery frame the serene outdoor setting.
Farm stay in Jasper
4.98 out of 5 average rating, 149 reviews

The Highland Hideaway (with Highland cows!)

The Highland Hideaway is a perfect place for the whole family to relax and enjoy. A small herd of Highland cows live here. A wet-weather creek is just behind the house, with a rock bluff and fire pit. There is a foos ball table and massage chair for your enjoyment after a day of hiking. The Hideaway is located 3 miles from Carver Landing. You'll be within easy access to SO MANY gorgeous places, including the national park. There is a second home on the property that can also be booked.

Top guest favorite
A screened porch features a round table surrounded by four chairs, all with green cushions. Natural light streams through the screens, showcasing views of a tranquil lake framed by colorful autumn foliage.
Guesthouse in Berwick
4.98 out of 5 average rating, 255 reviews

Private Guest Lake House On 37 Acres In Country

Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Top guest favorite
The treehouse sits elevated among trees, showcasing a spacious deck with circular windows. Leaves and twigs cover the ground, while a gentle stream flows nearby. A hammock is visible, inviting relaxation within the serene natural landscape.
Home in Fayetteville
5 out of 5 average rating, 320 reviews

A Luxury Treehouse Experience | Wood-Fired Cedar Hot Tub

Welcome to Whitetail & Pine, a Luxury Treehouse Experience. Nestled in the branches of two centuries old red oak trees and suspended 25 feet above Goose Creek, this arboreal abode offers a unique twist on traditional lodging. If you are seeking a rejuvenating getaway accented with the sights and sounds of nature, yet desire to be close to Fayetteville’s best restaurants and attractions, look no further than the Treehouse @ Whitetail & Pine. If you are on the fence, check out our reviews!

Top guest favorite
The treehouse, elevated 35 feet in the air, features a natural wooden structure with a thatched roof. Surrounding greenery includes tall trees and lush plants. A wooden sign reading 'Tropical Treehouse' is positioned in the foreground, complemented by a small, nearby covered seating area.
Treehouse in Arkadelphia
5 out of 5 average rating, 244 reviews

The Treehouse is a quiet and peaceful retreat.

Tropical Treehouse set in a ten acre Jungle Garden with a canal lagoon. Private mature forest park of 250 acres and five miles of nature trails. There are four lakes and the Treehouse overlooks Lake Winnamocka. The house is 35 feet in the air accessible by stairs but with a cargo lift for luggage and groceries. The bath is tile with heated floor and tile shower. There is a bidet, washer/dryer in the full bath. The kitchen is modern. There are 3 porches. Master bed and two loft bunks.

Top guest favorite
A screened-in porch features two woven armchairs positioned around a small table. The view highlights a serene landscape with a lake and mountains in the distance, bathed in the warm colors of sunrise. A colorful rug adds a cozy touch underfoot.
Home in Mountainburg
4.95 out of 5 average rating, 119 reviews

Locust Mountain View

This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!

Top guest favorite
A rustic cabin exterior features wooden logs and stone accents, seamlessly integrating with the natural surroundings. A set of steps leads to a welcoming porch equipped with two wooden chairs for outdoor relaxation. Lush greenery and trees frame the cabin, enhancing the secluded atmosphere.
Cabin in Broken Bow
4.96 out of 5 average rating, 232 reviews

Couples Cabin/Hot Tub/Fire Pit/Peaceful/Private

Make Memories at "LEATHERWOOD" for couples or a small family! ☆ Private hot tub ☆ BBQ grill ☆ Private outdoor kitchen ☆ Barbecue utensils ☆ Outdoor furniture ☆ Fire pit ☆ Patio or balcony ☆ Private backyard ☆ Single level home ☆ Coffee maker: Keurig coffee machine ☆ 50 inch HDTV with Amazon Prime Video, Disney+, Netflix, Hulu, Roku ☆ Books and reading material ☆Private entrance ☆ Board games ☆ Free parking on premises ☆ Fast, free Wi-Fi ☆ AC & Heating- split type ductless system

Top guest favorite
The treehouse is illuminated at night, highlighting its modern architecture nestled among trees. Warm lights glow from the windows, contrasting with the dark sky. Surrounding foliage displays vibrant orange hues, adding a serene ambiance to the outdoor setting.
Treehouse in Hermann
4.99 out of 5 average rating, 147 reviews

Out On A Limb Treehouse

A unique Treehouse, 6 miles from Hermann, MO, offers a luxury escape with stunning views and sunsets. Perched on stilts by Daniel Boone Conservation Area, enjoy tranquility, hiking, and wildlife. Relax in a king-size bed beneath skylights, soak in a tub, or unwind in the hot tub and firepit. Just a mile from the Katy Trail, perfect for cycling or relaxing. Explore Hermann’s wineries, shops, and events. Transportation available from Hermann Trolley, Uber & Lyft. Sleeps 2 adults.

Top guest favorite
Cottage in Wheatland
4.97 out of 5 average rating, 435 reviews

Cozy Woodland Cottage

This cozy cottage in the woods (completed in June 2017) is perfect for a couple seeking a romantic getaway, enjoying a honeymoon, or celebrating an anniversary. (The sofa is a full convertible bed, if others plan to share the 400+ sq. ft. space.) Located in the Lake Hill (formerly Shadow Lake) Golf Course neighborhood (course is currently closed) about a mile from the NW shores of beautiful Pomme de Terre Lake, and about 6 miles south of Lucas Oil Speedway.

Top guest favorite
A spacious living area showcases wooden beams and walls, creating a warm atmosphere. Large, angled windows provide views of surrounding trees. Comfortable seating arrangements include a white sofa and two armchairs on a textured rug, complemented by a natural stone fireplace offering a rustic touch.
Treehouse in Ozark
4.98 out of 5 average rating, 250 reviews

Treehouse in the Ozarks w/Hot Tub, on 2 Acres

Escape the hustle and bustle and retreat to our cozy treehouse nestled in the Ozark wilderness. Our one-of-a-kind cabin features 4 decks, 2 electric fire places, 1 wood stove, spiral staircase, indoor rock waterfall and hidden reading/painting nook. Enjoy the outdoors while relaxing in the hot tub taking in the serene view. Within 30 minutes of dining, bars, entertainment, Table Rock Lake, amusement parks and more!

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