Vacation rentals in Mississippi River

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Top-rated vacation rentals in Mississippi River

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Cabin in Elizabeth
4.99 out of 5 average rating, 106 reviews

Secluded Lakefront Estate | Couples Retreat

Welcome to Sunset Cove on Norfork Lake, a secluded 60-acre gated lakefront estate where modern luxury meets untouched Ozark wilderness. Wake up to sweeping lake views, spend the day at the luxury pool overlooking Norfork Lake, kayak from lakeside decks in a quiet cove, and unwind in the private hot tub beneath the stars. With only two other rentals spread across the property and 500+ acres of surrounding wilderness, this is a rare escape designed for connection and unforgettable moments together

Top guest favorite
A rustic cabin exterior is framed by lush green grass and trees. The wooden structure features a stone chimney and a distinctive blue door, with two large windows on the left. A simple stone path leads to the entrance, inviting relaxation in a natural setting.
Cabin in Chanute
4.98 out of 5 average rating, 608 reviews

The Blue Door Cabin

If you want a retreat where you can sleep in, slow down and savor nature's beauty, the Blue Door Cabin, tucked in surprisingly hilly oak and hickory woods, with a beautiful view of the pond, is your destination. Within two hours from Kansas City, Tulsa, Joplin or Wichita, and only 4 miles from Chanute Kansas, this preserved and revived cabin offers an easy getaway for city dwellers in need of a very affordable anniversary weekend, study or solitude retreat, or family hiking and fishing trip.

Top guest favorite
A screened porch features a round table surrounded by four chairs, all with green cushions. Natural light streams through the screens, showcasing views of a tranquil lake framed by colorful autumn foliage.
Guesthouse in Berwick
4.98 out of 5 average rating, 257 reviews

Private Guest Lake House On 37 Acres In Country

Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Top guest favorite
The treehouse structure is elevated, supported by stilts, with large windows that reflect the surrounding greenery. The exterior features a combination of wood finishes, and warm lighting casts a welcoming glow in the evening. The pathway leads through the natural landscape to the entrance.
Treehouse in Perryville
5 out of 5 average rating, 700 reviews

Private Treehouse Retreat | Hot tub

The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.

Top guest favorite
A screened-in porch features two woven armchairs positioned around a small table. The view highlights a serene landscape with a lake and mountains in the distance, bathed in the warm colors of sunrise. A colorful rug adds a cozy touch underfoot.
Home in Mountainburg
4.95 out of 5 average rating, 126 reviews

Locust Mountain View

This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!

Top guest favorite
The exterior of the Grain Bin Cabin is showcased beside a tranquil pond, reflecting the cabin's metallic structure. Adirondack chairs surround a firepit on the grass, with picnic tables positioned nearby, creating an inviting outdoor space.
Cabin in Versailles
4.99 out of 5 average rating, 185 reviews

The Highland GrainBin, Highland Cows, Firepit

Welcome to our charming boho-inspired Grain Bin Cabin, the Highland is ideal for 2-3 adults or 2 adults and 2 smaller children. Upstairs, you'll find a comfortable king bed in the loft, while downstairs features a cozy futon in the main living space. The full kitchen is equipped with everything you need. Full Bath with a walk-in shower downstairs. Experience a serene countryside getaway with breathtaking sunsets and peaceful surroundings, just moments away from Versailles.

Top guest favorite
A two-story treehouse is set amongst lush trees, featuring a warm brown exterior with contrasting black accents. A wooden ramp leads to the entrance, providing accessibility. The surrounding nature is visible, enhancing the sense of seclusion in this tranquil retreat.
Treehouse in Rogers
4.97 out of 5 average rating, 193 reviews

TreeHouse, Hot Tub, Views, Lake

Escape to a brand-new, 2-story treehouse near Beaver Lake! Enjoy nature views from the deck with a recessed stock tank hot tub, stay cozy with an electric fireplace, and cook in the fully stocked kitchen. This unique retreat offers 2 bedrooms (one is a loft accessed by ladder), 3 beds, and sleeps 5. With fast WiFi and a mini-split HVAC system for room-specific climate control, you'll feel secluded yet close to Rogers' attractions. Perfect for a peaceful, modern getaway!

Top guest favorite
A wooden barrel sauna interior features two benches on opposite sides, creating a cozy space. The large arched window reveals a serene forest view. A wood bucket and a heater are positioned at the center, contributing to the rustic charm.
Cabin in Broken Bow
4.97 out of 5 average rating, 146 reviews

Romantic Getaway - Hot Tub, Sauna & Coffee Bar

Welcome to Sweet Serendipity - A Romantic Woodland Escape Luxury Amenities: 🧖Barrel Sauna w/Accessories 🔥Firepit w/Large Daybed Swing & Chairs ♨️Private Back Deck w/Sectional, Jacuzzi, & Outdoor Fireplace ☕Fully Stocked Coffee Bar 🥇Cornhole Set with Complimentary Koozies 💪Exercise Equipment: Lululemon Yoga Mats & Blocks, 2 Adjustable 25lb Dumbbells, Resistance Bands, Weighted Jump Rope & Foam Roller 🏞️Outdoor Equipment: Hiking Rods, Fishing Rods & Accessories

Top guest favorite
The cabin features a welcoming exterior with wooden steps leading to a covered deck. Red doors complement the neutral siding, surrounded by a gravel area and framed by colorful autumn trees. A hammock and chair are positioned nearby, inviting relaxation.
Cabin in Compton
4.99 out of 5 average rating, 180 reviews

Private Trail to Overlook Cell service Wifi

Wake up in the Ozarks and step out the door and onto a private trail leading to a bluff-top overlook—no driving, no crowds, just you and the view. This secluded cabin sits on private land bordering the Buffalo National River, just a short drive to Ponca. Guests love the direct hiking, scenic overlooks, and seasonal waterfalls. Enjoy reliable cell service and high-speed internet—rare for this area. A true hiker’s basecamp to experience the outdoors.

Top guest favorite
Tent in Hot Springs
5 out of 5 average rating, 346 reviews

Fern Dell Woodland Glamp - Air Conditioned Tent!

Relax in a secluded and cozy glam-camp for two on 16 wooded acres just 3 miles from downtown Hot Springs National Park! Prepare full meals in a well-equipped woodland kitchen. Hike or bike private onsite trails. Enjoy a crackling fire against the mountain sunset. Star gaze from the 2-person hammock and sleep soundly in a real queen bed in an air conditioned canvas tent. CONTINUE READING for important details

Top guest favorite
A tranquil outdoor space is presented with two Adirondack chairs positioned next to a stone fire pit. A pathway leads to a modern wooden loft elevated above the ground, surrounded by trees and a neatly stacked pile of firewood.
Guesthouse in Hasty
4.99 out of 5 average rating, 142 reviews

The Loft - Mt. Views & Close River Access (0.7)

Created just for two, this cozy haven is the perfect base camp for your outdoor adventures. The Loft features gorgeous mountain views and quick access to the Buffalo River. This 352 square foot modern studio boasts an exceptional outdoor living space. Sit on the porch with your morning coffee before you head out for adventure and keep an eye out for the deer that feel right at home on our 40 acre property.

Top guest favorite
A cozy outdoor seating area is highlighted by a gas fire pit, with flames dancing over a bed of stones. The distant horizon showcases a sunset with vibrant colors, while the private hot tub is visible nearby, surrounded by the open landscape.
Home in Carthage
5 out of 5 average rating, 188 reviews

The Perfect Retreat: Modern Tiny Home- Hot Tub

A cozy and romantic luxury tiny home with a private hot tub under the stars. Wake up with coffee on the porch swing, watch the sunset from the spa, and unwind by the firelight in the evenings. Designed for slow mornings, peaceful nights, and reconnecting — just outside Carthage and next to I-44, enjoy the countryside and easy access to town. Perfect for couples, solo retreats, or a small, restful escape.

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