Vacation rentals in Mississippi River

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Mississippi River

Guests agree: these stays are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Top guest favorite
Cabin in Elizabeth
4.99 out of 5 average rating, 101 reviews

Secluded Lakefront Estate | Couples Retreat

Welcome to Sunset Cove on Norfork Lake, a secluded 60-acre gated lakefront estate where modern luxury meets untouched Ozark wilderness. Designed for couples seeking a rare escape where time slows, distractions fade, and world feels far. Mornings unfold slowly and evenings are peaceful, with sweeping lake views throughout the day. Spend your time exploring together between the water, hot tub, and quiet lakeside spaces in nature — a setting designed for stillness, connection, uninterrupted moments

Top guest favorite
A rustic cabin exterior is framed by lush green grass and trees. The wooden structure features a stone chimney and a distinctive blue door, with two large windows on the left. A simple stone path leads to the entrance, inviting relaxation in a natural setting.
Cabin in Chanute
4.98 out of 5 average rating, 601 reviews

The Blue Door Cabin

If you want a retreat where you can sleep in, slow down and savor nature's beauty, the Blue Door Cabin, tucked in surprisingly hilly oak and hickory woods, with a beautiful view of the pond, is your destination. Within two hours from Kansas City, Tulsa, Joplin or Wichita, and only 4 miles from Chanute Kansas, this preserved and revived cabin offers an easy getaway for city dwellers in need of a very affordable anniversary weekend, study or solitude retreat, or family hiking and fishing trip.

Top guest favorite
A fire pit surrounded by several light-colored chairs sits on a grassy area. In the background, a single-story house is visible along with a covered porch and outdoor seating. Lush trees and greenery frame the serene outdoor setting.
Farm stay in Jasper
4.98 out of 5 average rating, 146 reviews

The Highland Hideaway (with Highland cows!)

The Highland Hideaway is a perfect place for the whole family to relax and enjoy. A small herd of Highland cows live here. A wet-weather creek is just behind the house, with a rock bluff and fire pit. There is a foos ball table and massage chair for your enjoyment after a day of hiking. The Hideaway is located 3 miles from Carver Landing. You'll be within easy access to SO MANY gorgeous places, including the national park. There is a second home on the property that can also be booked.

Top guest favorite
The treehouse sits elevated among trees, showcasing a spacious deck with circular windows. Leaves and twigs cover the ground, while a gentle stream flows nearby. A hammock is visible, inviting relaxation within the serene natural landscape.
Home in Fayetteville
5 out of 5 average rating, 319 reviews

A Luxury Treehouse Experience | Wood-Fired Cedar Hot Tub

Welcome to Whitetail & Pine, a Luxury Treehouse Experience. Nestled in the branches of two centuries old red oak trees and suspended 25 feet above Goose Creek, this arboreal abode offers a unique twist on traditional lodging. If you are seeking a rejuvenating getaway accented with the sights and sounds of nature, yet desire to be close to Fayetteville’s best restaurants and attractions, look no further than the Treehouse @ Whitetail & Pine. If you are on the fence, check out our reviews!

Top guest favorite
A mountaintop cabin is showcased with a red metal roof and deck extending from the front. The cabin is surrounded by greenery, with large rocks and landscaped areas visible at the base. Two stories are highlighted against a backdrop of trees.
Cabin in Fayetteville
4.99 out of 5 average rating, 148 reviews

Ponderosa Cabin South of Fayetteville

Make some memories at this family-friendly mountaintop cabin south of Fayetteville. This unique cabin is located on 50 acres that offer a million-dollar view of the Boston Mountains. Enjoy fishing in the large pond with the fishing poles, tackle, and enjoy the challenge of a scavenger hunt along the 1/2 mile-long hiking trail! In the evening, enjoy the cliffside firepit nestled next to the peaceful waterfall! 11-minute drive to Razorback Stadium and 5 minutes from the interstate!

Top guest favorite
The treehouse structure is elevated, supported by stilts, with large windows that reflect the surrounding greenery. The exterior features a combination of wood finishes, and warm lighting casts a welcoming glow in the evening. The pathway leads through the natural landscape to the entrance.
Treehouse in Perryville
5 out of 5 average rating, 695 reviews

Private Treehouse Retreat | Hot tub

The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.

Top guest favorite
A screened-in porch features two woven armchairs positioned around a small table. The view highlights a serene landscape with a lake and mountains in the distance, bathed in the warm colors of sunrise. A colorful rug adds a cozy touch underfoot.
Home in Mountainburg
4.95 out of 5 average rating, 118 reviews

Locust Mountain View

This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!

Top guest favorite
A treehouse perched among lush greenery is presented, featuring a large balcony that offers views of the surrounding landscape. The structure is elevated above the ground, supported by wooden beams, set against a backdrop of blue skies and scattered clouds.
Treehouse in Jasper
4.98 out of 5 average rating, 235 reviews

Sunrise + Mountain Views • Firepit • Buffalo Hikes

Welcome to Canyon View Treehouse! Indulge in a unique and unforgettable stay at our Canyon View Treehouse. Located in the heart of Arkansas, you'll be surrounded by gorgeous mountains and spectacular views of the Arkansas Grand Canyon. Take a moment to relax and unwind on the spacious balcony, where you can sip on a cup of coffee while soaking in the natural beauty of the area. At Buffalo River Vacations our goal is to go above & beyond so our guests have an unforgettable getaway!

Top guest favorite
The exterior of the Grain Bin Cabin is showcased beside a tranquil pond, reflecting the cabin's metallic structure. Adirondack chairs surround a firepit on the grass, with picnic tables positioned nearby, creating an inviting outdoor space.
Cabin in Versailles
4.99 out of 5 average rating, 173 reviews

The Highland GrainBin, Highland Cows, Firepit

Welcome to our charming boho-inspired Grain Bin Cabin, the Highland is ideal for 2-3 adults or 2 adults and 2 smaller children. Upstairs, you'll find a comfortable king bed in the loft, while downstairs features a cozy futon in the main living space. The full kitchen is equipped with everything you need. Full Bath with a walk-in shower downstairs. Experience a serene countryside getaway with breathtaking sunsets and peaceful surroundings, just moments away from Versailles.

Top guest favorite
A cozy living area features log walls, a stone fireplace, and a large flat-screen TV. Comfortable seating is provided by soft armchairs and a leather couch. Natural light enters through a window, illuminating the plush area rug and inviting atmosphere.
Cabin in Rudy
4.97 out of 5 average rating, 174 reviews

Log Cabin/100 acres/One of a kind/Wifi-Cuddly Cow

The Cuddly Cow features a full kitchen with laundry, eating bar and dining area. There is one large bedroom with a king size bed. The room has a slider out to the front with table and chairs to have a peaceful enjoyment of nature. Full size bathroom with shower over tub and dual sinks. There is a pool next to this cabin that is not useable for guests due to insurance limitations. We have 3 addt'l cabins on the property, Velvet Rooster, Happy Hound & Pampered Peacock.

Top guest favorite
The cottage is nestled among dense trees, featuring a welcoming front porch with white railings. Large windows allow natural light to enter, while a set of stairs leads up to the entrance. The surrounding greenery creates a serene, secluded atmosphere.
Cottage in Wheatland
4.97 out of 5 average rating, 434 reviews

Cozy Woodland Cottage

This cozy cottage in the woods (completed in June 2017) is perfect for a couple seeking a romantic getaway, enjoying a honeymoon, or celebrating an anniversary. (The sofa is a full convertible bed, if others plan to share the 400+ sq. ft. space.) Located in the Lake Hill (formerly Shadow Lake) Golf Course neighborhood (course is currently closed) about a mile from the NW shores of beautiful Pomme de Terre Lake, and about 6 miles south of Lucas Oil Speedway.

Top guest favorite
A park model home is positioned on a stone terrace, surrounded by lush greenery. Large windows offer expansive views of the surrounding landscape. A wooden deck with seating is visible, extending the living space outdoors, with a tranquil atmosphere conveyed by the scenic backdrop.
Cabin in De Soto
4.96 out of 5 average rating, 138 reviews

Paradise Point sleeps 2 Hot Tub

1 bedroom 1 bath with loft. Cozy home where you can see Paradise. This memorable place is anything but ordinary. Views for miles of the Mississippi River, bluff tops and you can soar with the Eagles. What a place to relax in the newly added hot tub while you enjoy the view in what is call "God's Country". This is promised to be a one of a kind view. The Deck with comfortable outdoor seating Located in the heart of WIsconsin's Driftless Region.

Popular amenities for Mississippi River vacation rentals

Destinations to explore