Vacation rentals in Mississippi River

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Top-rated vacation rentals in Mississippi River

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Cabin in Elizabeth
4.99 out of 5 average rating, 117 reviews

Secluded Lakefront Estate | Couples Retreat

Welcome to Sunset Cove on Norfork Lake, a secluded 60-acre gated lakefront estate where modern luxury meets untouched Ozark wilderness. Wake up to sweeping lake views, spend the day at the luxury pool overlooking Norfork Lake, kayak from lakeside decks in a quiet cove, and unwind in the private hot tub beneath the stars. With only two other rentals spread across the property and 500+ acres of surrounding wilderness, this is a rare escape designed for connection and unforgettable moments together

Top guest favorite
A rustic home built of natural wood is framed by blooming pink trees and lush green grass. The structure features a spacious porch with seating, while large windows allow views into the inviting interior.
Farm stay in Steelville
4.98 out of 5 average rating, 173 reviews

Yeary Farms Milt's Place with Private Beach!

An Ozark Oasis in the middle of a working cattle ranch, this custom designed home offers deluxe comfort. With multiple decks, porches and views out every window, this home is the perfect getaway for romantic retreats, family and friends to relax and make memories, artists and writers to host workshops or retreats, or even the single person to just get away from it all. Good dogs welcome, $35 per dog per week, fee collected separately at time of check in. Look for Yeary Farms site for more info.

Top guest favorite
A charming cottage sits beside a tranquil spring-fed pond, featuring a large deck accessible from the rear. A fire pit resides in the grassy area, with lush green trees surrounding the property, enhancing the peaceful outdoor setting.
Cottage in New Eucha
4.99 out of 5 average rating, 168 reviews

Private Spring Fed Reservoir w/paddle boat

Off the beaten path, approximately 1 mile down a bumpy dirty road you will find a hidden gem. At the edge of the Ozarks in the heart of green country is a small cottage located on a beautiful one acre spring feed pond. You can see the spring gushing out of the hillside. Our cottage is small, cozy, and very relaxing. Whether you are kicking back watching the tube or paddling around the pond you will feel right at home and may not want to leave. Paddle boat, 4 paddle boards and 2 kayaks included

Top guest favorite
A rustic cabin exterior is framed by lush green grass and trees. The wooden structure features a stone chimney and a distinctive blue door, with two large windows on the left. A simple stone path leads to the entrance, inviting relaxation in a natural setting.
Cabin in Chanute
4.98 out of 5 average rating, 620 reviews

The Blue Door Cabin

If you want a retreat where you can sleep in, slow down and savor nature's beauty, the Blue Door Cabin, tucked in surprisingly hilly oak and hickory woods, with a beautiful view of the pond, is your destination. Within two hours from Kansas City, Tulsa, Joplin or Wichita, and only 4 miles from Chanute Kansas, this preserved and revived cabin offers an easy getaway for city dwellers in need of a very affordable anniversary weekend, study or solitude retreat, or family hiking and fishing trip.

LocationComfort

Top guest favorite
The treehouse, elevated 35 feet in the air, features a natural wooden structure with a thatched roof. Surrounding greenery includes tall trees and lush plants. A wooden sign reading 'Tropical Treehouse' is positioned in the foreground, complemented by a small, nearby covered seating area.
Treehouse in Arkadelphia
5.0 out of 5 average rating, 259 reviews

The Treehouse is a quiet and peaceful retreat.

Tropical Treehouse set in a ten acre Jungle Garden with a canal lagoon. Private mature forest park of 250 acres and five miles of nature trails. There are four lakes and the Treehouse overlooks Lake Winnamocka. The house is 35 feet in the air accessible by stairs but with a cargo lift for luggage and groceries. The bath is tile with heated floor and tile shower. There is a bidet, washer/dryer in the full bath. The kitchen is modern. There are 3 porches. Master bed and two loft bunks.

Top guest favorite
A mountaintop cabin is showcased with a red metal roof and deck extending from the front. The cabin is surrounded by greenery, with large rocks and landscaped areas visible at the base. Two stories are highlighted against a backdrop of trees.
Cabin in Fayetteville
4.99 out of 5 average rating, 159 reviews

Ponderosa Cabin South of Fayetteville

Make some memories at this family-friendly mountaintop cabin south of Fayetteville. This unique cabin is located on 50 acres that offer a million-dollar view of the Boston Mountains. Enjoy fishing in the large pond with the fishing poles, tackle, and enjoy the challenge of a scavenger hunt along the 1/2 mile-long hiking trail! In the evening, enjoy the cliffside firepit nestled next to the peaceful waterfall! 11-minute drive to Razorback Stadium and 5 minutes from the interstate!

Top guest favorite
A spacious living area features a comfortable sofa facing a fireplace and a wall-mounted television. Natural light floods the space through large windows, providing views of the deck and surrounding greenery. A dining table for six is positioned nearby, complemented by a woven light fixture.
Guesthouse in Blue Eye
4.97 out of 5 average rating, 299 reviews

Turtle Cove- Hot tub, Kayaks, Fire Wood Included

Come and enjoy a peaceful getaway in our quiet cove on Table Rock Lake. Relax in our guest house with a private deck, hot tub, outdoor shower, fire pit and beach at your back door! Enjoy swimming or fishing in the cove, sunning on a paddle board or kayaking at sunset. Paddle boards and kayaks included! Welcome family time relaxing on the hammock listening to the water lapping, barbecuing on the deck or chilling by the fire pit (firewood included). Come rejuvenate in nature's beauty!!

Top guest favorite
The treehouse structure is elevated, supported by stilts, with large windows that reflect the surrounding greenery. The exterior features a combination of wood finishes, and warm lighting casts a welcoming glow in the evening. The pathway leads through the natural landscape to the entrance.
Treehouse in Perryville
5.0 out of 5 average rating, 716 reviews

Private Treehouse Retreat | Hot tub

The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.

Top guest favorite
A welcoming view of the Sassafrass Silo reveals a wooden deck leading to the entrance. A decorative flower planter labeled 'HEY Y'ALL' sits in the foreground, surrounded by lush greenery and colorful flowers. The fire pit area with red chairs is located beside the silo, inviting outdoor relaxation.
Treehouse in Eagle Rock
4.98 out of 5 average rating, 371 reviews

Sassafrass Silo Treehouse on Table Rock Lake

The Sassafrass Silo began life as a grain silo that Mike found on a farm in Kansas. We felt she had more life left in her, so we took her from field to forest and gave her a new purpose! Her new journey is based on Debbie's family history from the beautiful Natchez, Mississippi. Her memories of serving in Pilgrimage in her own hoop skirt and classic charm of the antebellum homes paired with her love of bohemian style, nature and the lake helped create this unique space!

Top guest favorite
The cottage is nestled among dense trees, featuring a welcoming front porch with white railings. Large windows allow natural light to enter, while a set of stairs leads up to the entrance. The surrounding greenery creates a serene, secluded atmosphere.
Cottage in Wheatland
4.98 out of 5 average rating, 443 reviews

Cozy Woodland Cottage

This cozy cottage in the woods (completed in June 2017) is perfect for a couple seeking a romantic getaway, enjoying a honeymoon, or celebrating an anniversary. (The sofa is a full convertible bed, if others plan to share the 400+ sq. ft. space.) Located in the Lake Hill (formerly Shadow Lake) Golf Course neighborhood (course is currently closed) about a mile from the NW shores of beautiful Pomme de Terre Lake, and about 6 miles south of Lucas Oil Speedway.

Top guest favorite
The cozy bedroom features a large bed with a checkered blanket and natural wood walls. A fan provides airflow, while a window allows soft light to enter. A dark wooden dresser stands nearby, contributing to the rustic charm of the space.
Cabin in St. James
4.99 out of 5 average rating, 237 reviews

Cedar Cabin-Angler’s Catch

Cedar Cabin w/King Bed, Fully Stocked Kitchen, Washer/Dryer, Walk-In Shower, Ramp Access, 2 Decks, Fire Pit, Grill, Free Parking, and 1.3 miles from Beautiful Maramec Spring Park. A trout fisherman’s catch or a couple’s cozy getaway. Close to several Ozark attractions including Maramec Springs Park, Montauk State Park, Current River, Huzzah River, and more. The cabin also has a love seat twin sofa sleeper and is 5 miles from town. Hope to see you soon 😉

Top guest favorite
A spacious living area showcases wooden beams and walls, creating a warm atmosphere. Large, angled windows provide views of surrounding trees. Comfortable seating arrangements include a white sofa and two armchairs on a textured rug, complemented by a natural stone fireplace offering a rustic touch.
Treehouse in Ozark
4.98 out of 5 average rating, 271 reviews

Treehouse in the Ozarks w/Hot Tub, on 2 Acres

Escape the hustle and bustle and retreat to our cozy treehouse nestled in the Ozark wilderness. Our one-of-a-kind cabin features 4 decks, 2 electric fire places, 1 wood stove, spiral staircase, indoor rock waterfall and hidden reading/painting nook. Enjoy the outdoors while relaxing in the hot tub taking in the serene view. Within 30 minutes of dining, bars, entertainment, Table Rock Lake, amusement parks and more!

Popular amenities for Mississippi River vacation rentals

Frequently Asked Questions

  • Where is Mississippi River located?

    The Mississippi River winds through the central United States, passing through states like Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana before reaching the Gulf of Mexico. Its banks host diverse communities and landscapes shaped by the river.

  • When is the best time to visit Mississippi River?

    Late spring and early fall are frequently suggested, as temperatures are milder and local events often take place. Summer provides lush scenery but can feel humid, while winter attracts those interested in quieter river landscapes.

  • What are some things to do near Mississippi River?

    You can explore riverfront parks, nature trails, and historic sites, or join boat tours to learn about local wildlife and history. The area also has museums, cultural events, and opportunities for fishing or paddling.

  • How is the weather near Mississippi River?

    Winters are generally cold, ranging from 22–44°F (-5–7°C), while summers reach 83–88°F (28–31°C) with humid conditions. Spring and fall are often recommended for milder temperatures and changing scenery along the river.

Destinations to explore