
Vacation rentals in Mississippi River
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Top-rated vacation rentals in Mississippi River
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The Wilderness Homestead Cave-HotTub-Hiking
Welcome to our Wilderness Retreat — an Oklahoma Ozark getaway with adventure built right in. At night, the property’s cave transforms into a magical haven , adorned w/soft lights and featuring a table for two. Indulge in the hot tub oasis with aromatherapy, floating candles and warm towels, relax by the fire pit, or walk the scenic trails. We’re 420-friendly, pet-friendly, and perfect for couples who want something unforgettable. We are within a couple miles of a clear local creek ! Ask for📍
LocationFamilyAccuracy
4.94 out of 5 average rating, 258 reviews
Yeary Farms Milt's Place with Private Beach!
An Ozark Oasis in the middle of a working cattle ranch, this custom designed home offers deluxe comfort. With multiple decks, porches and views out every window, this home is the perfect getaway for romantic retreats, family and friends to relax and make memories, artists and writers to host workshops or retreats, or even the single person to just get away from it all. Good dogs welcome, $35 per dog per week, fee collected separately at time of check in. Look for Yeary Farms site for more info.
FamilyValuePets
4.98 out of 5 average rating, 173 reviews
Private Lakefront Romantic Cottage w/Swimspa&sauna
This cozy cottage is for couples looking to escape from it all and regenerate on many levels. You'll have your very own steam shower ....check out the company description.... . "Featuring 10 acupuncture jets, sunken tub and a high efficiency steam engine, the 608P steam bath is designed to greatly increase your spa experience. Indulge yourself in a state of complete relaxation". You'll also enjoy the comfy bed, fully stocked kitchen, private deck and access to a Swimspa and sauna 100 ft away.
FamilyLocationCondition
4.96 out of 5 average rating, 495 reviews
The Blue Door Cabin
If you want a retreat where you can sleep in, slow down and savor nature's beauty, the Blue Door Cabin, tucked in surprisingly hilly oak and hickory woods, with a beautiful view of the pond, is your destination. Within two hours from Kansas City, Tulsa, Joplin or Wichita, and only 4 miles from Chanute Kansas, this preserved and revived cabin offers an easy getaway for city dwellers in need of a very affordable anniversary weekend, study or solitude retreat, or family hiking and fishing trip.
ValueLocationHospitality
4.98 out of 5 average rating, 622 reviews
A Luxury Treehouse Experience | Wood-Fired Cedar Hot Tub
Welcome to Whitetail & Pine, a Luxury Treehouse Experience. Nestled in the branches of two centuries old red oak trees and suspended 25 feet above Goose Creek, this arboreal abode offers a unique twist on traditional lodging. If you are seeking a rejuvenating getaway accented with the sights and sounds of nature, yet desire to be close to Fayetteville’s best restaurants and attractions, look no further than the Treehouse @ Whitetail & Pine. If you are on the fence, check out our reviews!
LocationValueParks
5.0 out of 5 average rating, 340 reviews
Private Treehouse Retreat | Hot tub
The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.
ValueFamilyPets
5.0 out of 5 average rating, 721 reviews
Locust Mountain View
This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!
ValueFamilyGrill
4.95 out of 5 average rating, 153 reviews
Sharing the view
Make some memories at this unique and serene place. Overlooking the beautiful Ozark mountains, enjoy the stunning sunrise, or take a ride on Buckhorn Trails with your side by side or four wheeler. A 25 minute drive to the University of Arkansas if calling the Hogs is more your style! We are a short drive to Lake Fort Smith state park here in Mountainburg for fishing or swimming in the pool. We have a beautiful deck, a comfortable bed, and grill for you to cook your favorite meals.
ValueLocationKitchen
5.0 out of 5 average rating, 246 reviews
Sassafrass Silo Treehouse on Table Rock Lake
The Sassafrass Silo began life as a grain silo that Mike found on a farm in Kansas. We felt she had more life left in her, so we took her from field to forest and gave her a new purpose! Her new journey is based on Debbie's family history from the beautiful Natchez, Mississippi. Her memories of serving in Pilgrimage in her own hoop skirt and classic charm of the antebellum homes paired with her love of bohemian style, nature and the lake helped create this unique space!
LocationValueNearby
4.98 out of 5 average rating, 375 reviews
River Cabin/UTV/Trails/Kayaks/HotTub/OutD Shower/
The James River Cabin is a luxurious secluded cabin nestled among the trees on 90 acres of river front property. It is just 10 short miles from Springfield, MO (Buc-ee’s and Bass Pro) less than an hour from Branson, MO. On-site activities are numerous and include bicycling, trail hiking, utv trail riding, kayaking, fishing, hot tubbing, and swimming in your own personal paradise. The river access is a short but fun two minute utv drive from the cabin.
FamilyValueBeach
4.98 out of 5 average rating, 320 reviews
Treehouse in the Ozarks w/Hot Tub, on 2 Acres
Escape the hustle and bustle and retreat to our cozy treehouse nestled in the Ozark wilderness. Our one-of-a-kind cabin features 4 decks, 2 electric fire places, 1 wood stove, spiral staircase, indoor rock waterfall and hidden reading/painting nook. Enjoy the outdoors while relaxing in the hot tub taking in the serene view. Within 30 minutes of dining, bars, entertainment, Table Rock Lake, amusement parks and more!
LocationValueWifi
4.98 out of 5 average rating, 273 reviews
Treehouse in Branson 10 min to SDC
Escape to Tree Hugger Hideaway, a custom-built treehouse with unmatched seclusion. Perfect for romantic getaways or family retreats, this treetop escape sits on 48 private acres of Ozark beauty, with private hiking trails and a pond. Proudly featured in Missouri Life Magazine, our treehouse has been recognized as one of Missouri’s most unique stays. Just 7 miles from Branson Landing & Silver Dollar City.
LocationValueLayout
5.0 out of 5 average rating, 187 reviewsPopular amenities for Mississippi River vacation rentals
Mississippi River house rentals

Bayou Lake House on Lake Hamilton
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4.97 out of 5 average rating, 299 reviews
Creek's End Riverside Retreat
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4.92 out of 5 average rating, 195 reviews
Lakefront Retreat w/ Hot Tub, Sauna & Cold Plunge
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4.98 out of 5 average rating, 155 reviews
Private Ozark Views| 20 Wooded Acres| Near Buffalo
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4.96 out of 5 average rating, 114 reviews
Reel-e Rustic Roost
FamilyLocationAccuracy
4.99 out of 5 average rating, 135 reviews
Lakefront | Dock • Sleeps 12 • Kayaks • Firepit
LocationValueBeach
4.99 out of 5 average rating, 137 reviews
The Clubhouse - Views, Hot Tub & Putting Green
LocationValueComfort
4.99 out of 5 average rating, 148 reviews
Views! Luxury A-Frame: Private Hot Tub & Fire Pit!
FamilyLocationCleanliness
4.97 out of 5 average rating, 184 reviewsOther great vacation rentals in Mississippi River

The Treehouse is a quiet and peaceful retreat.
FamilyValueAir conditioning
5.0 out of 5 average rating, 260 reviews
The Grainery with Hot Tub
ValueFamilyKitchen
4.99 out of 5 average rating, 160 reviews
Private Spring Fed Reservoir w/paddle boat
ValueLocationParking
4.99 out of 5 average rating, 169 reviews
Thunder Mountain Riverfront Cabin - Caddo Gap, AR
FamilyValueCheck-in
4.95 out of 5 average rating, 129 reviews
Luxury Lakeview Treehouse • Stunning Views • Lake
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5.0 out of 5 average rating, 107 reviews
The Hideaway
ValueFamilyCleanliness
4.99 out of 5 average rating, 501 reviews
The Winsome Loft- Arcade & Home Theater
ValueFamilyCheck-in
4.97 out of 5 average rating, 646 reviews
Paradise Point sleeps 2 Hot Tub
ValueFamilyNearby
4.96 out of 5 average rating, 161 reviewsFrequently Asked Questions
Where is Mississippi River located?
The Mississippi River winds through the central United States, passing through states like Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana before reaching the Gulf of Mexico. Its banks host diverse communities and landscapes shaped by the river.
When is the best time to visit Mississippi River?
Late spring and early fall are frequently suggested, as temperatures are milder and local events often take place. Summer provides lush scenery but can feel humid, while winter attracts those interested in quieter river landscapes.
What are some things to do near Mississippi River?
You can explore riverfront parks, nature trails, and historic sites, or join boat tours to learn about local wildlife and history. The area also has museums, cultural events, and opportunities for fishing or paddling.
How is the weather near Mississippi River?
Winters are generally cold, ranging from 22–44°F (-5–7°C), while summers reach 83–88°F (28–31°C) with humid conditions. Spring and fall are often recommended for milder temperatures and changing scenery along the river.
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