
Vacation rentals in Mississippi River
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Mississippi River
Guests agree: these stays are highly rated for location, cleanliness, and more.

Secluded Lakefront Estate | Couples Retreat
Welcome to Sunset Cove on Norfork Lake, a secluded 60-acre gated lakefront estate where modern luxury meets untouched Ozark wilderness. Wake up to sweeping lake views, spend the day at the luxury pool overlooking Norfork Lake, kayak from lakeside decks in a quiet cove, and unwind in the private hot tub beneath the stars. With only two other rentals spread across the property and 500+ acres of surrounding wilderness, this is a rare escape designed for connection and unforgettable moments together

Glass Front Cabin with Stunning Lake View
Located on Beaver Lake with a stunning view of the water and lots of amenities. Snuggle up to a cozy fireplace. Relax in a candlelit Jacuzzi for two (not a hot tub) overlooking the beautiful scenery of the Ozark Mountains. Doze off to sleep in a pillow-top, king size Sleep Number bed while gazing at the stars and tree tops through the glass gables. Enjoy the deck with gas grill and a complete kitchen fully-stocked with utensils & supplies. Pet Fee: $75 - 1st dog; $25 - 2nd dog. 2 max. No cats

Eagle View Lodge - 1850's Log Cabin w/ Hot Tub
In the heart of the Driftless, atop the Mississippi , enjoy the tranquility of a centuries-old Appalachian cabin. Relax on the deck & take in dramatic sunsets, soaring eagles & glistening stars. Soak in the hot tub & gaze at the majestic Mississippi. Host unforgettable dinners in the screened deck & share stories by the fireplace. Only 30 mins from Viroqua & Prairie du Chien, experience the natural beauty of the driftless region - hiking, fishing, hunting, biking - whatever inspires you.

A Luxury Treehouse Experience | Wood-Fired Cedar Hot Tub
Welcome to Whitetail & Pine, a Luxury Treehouse Experience. Nestled in the branches of two centuries old red oak trees and suspended 25 feet above Goose Creek, this arboreal abode offers a unique twist on traditional lodging. If you are seeking a rejuvenating getaway accented with the sights and sounds of nature, yet desire to be close to Fayetteville’s best restaurants and attractions, look no further than the Treehouse @ Whitetail & Pine. If you are on the fence, check out our reviews!

Ponderosa Cabin South of Fayetteville
Make some memories at this family-friendly mountaintop cabin south of Fayetteville. This unique cabin is located on 50 acres that offer a million-dollar view of the Boston Mountains. Enjoy fishing in the large pond with the fishing poles, tackle, and enjoy the challenge of a scavenger hunt along the 1/2 mile-long hiking trail! In the evening, enjoy the cliffside firepit nestled next to the peaceful waterfall! 11-minute drive to Razorback Stadium and 5 minutes from the interstate!

Private Treehouse Retreat | Hot tub
The TreeLoft is the first of two treehouses at BaseCamp—designed for cozy seclusion, romance, and rest. Nestled in a private forest just 1 hour from St. Louis, it blends upscale comfort with immersive nature, while still being 20–35 minutes from hiking, wineries, and dining. ✨Our NEW treehouse, The TreeRise, offers an even more elevated, spacious experience at BaseCamp. Perfect for romantic getaways, anniversaries, personal retreats, and intentional escapes to unplug and reconnect.

Locust Mountain View
This unique place has a style all its own. 5 minutes off the interstate and you can wake up to the most beautiful sunrises and views that Arkansas has to offer. This home has all the amenities you are looking for while still making you feel like you are away from the rest of the world. In the master bedroom we have a king size adjustable mattress that you can set to your exact preference. We are a quick drive to Fayetteville if calling the Hogs and great eateries is more your style!

Sunrise + Mountain Views • Firepit • Buffalo Hikes
Welcome to Canyon View Treehouse! Indulge in a unique and unforgettable stay at our Canyon View Treehouse. Located in the heart of Arkansas, you'll be surrounded by gorgeous mountains and spectacular views of the Arkansas Grand Canyon. Take a moment to relax and unwind on the spacious balcony, where you can sip on a cup of coffee while soaking in the natural beauty of the area. At Buffalo River Vacations our goal is to go above & beyond so our guests have an unforgettable getaway!

TreeHouse, Hot Tub, Views, Lake
Escape to a brand-new, 2-story treehouse near Beaver Lake! Enjoy nature views from the deck with a recessed stock tank hot tub, stay cozy with an electric fireplace, and cook in the fully stocked kitchen. This unique retreat offers 2 bedrooms (one is a loft accessed by ladder), 3 beds, and sleeps 5. With fast WiFi and a mini-split HVAC system for room-specific climate control, you'll feel secluded yet close to Rogers' attractions. Perfect for a peaceful, modern getaway!

Sassafrass Silo Treehouse on Table Rock Lake
The Sassafrass Silo began life as a grain silo that Mike found on a farm in Kansas. We felt she had more life left in her, so we took her from field to forest and gave her a new purpose! Her new journey is based on Debbie's family history from the beautiful Natchez, Mississippi. Her memories of serving in Pilgrimage in her own hoop skirt and classic charm of the antebellum homes paired with her love of bohemian style, nature and the lake helped create this unique space!

Paradise Point sleeps 2 Hot Tub
1 bedroom 1 bath with loft. Cozy home where you can see Paradise. This memorable place is anything but ordinary. Views for miles of the Mississippi River, bluff tops and you can soar with the Eagles. What a place to relax in the newly added hot tub while you enjoy the view in what is call "God's Country". This is promised to be a one of a kind view. The Deck with comfortable outdoor seating Located in the heart of WIsconsin's Driftless Region.

Treehouse in the Ozarks w/Hot Tub, on 2 Acres
Escape the hustle and bustle and retreat to our cozy treehouse nestled in the Ozark wilderness. Our one-of-a-kind cabin features 4 decks, 2 electric fire places, 1 wood stove, spiral staircase, indoor rock waterfall and hidden reading/painting nook. Enjoy the outdoors while relaxing in the hot tub taking in the serene view. Within 30 minutes of dining, bars, entertainment, Table Rock Lake, amusement parks and more!
Popular amenities for Mississippi River vacation rentals
Mississippi River house rentals

Rippling Point Lakefront House

Emerald A Lakefront w/ Hot Tub

Tree House Luxury Stay

Treehouse in Branson 10 min to SDC

Private Ozark Views| 20 Wooded Acres| Near Buffalo

Mississippi River House

Views! Luxury A-Frame: Private Hot Tub & Fire Pit!

Lakefront Retreat w/ Hot Tub, Sauna & Cold Plunge
Other great vacation rentals in Mississippi River

The Treehouse is a quiet and peaceful retreat.

Luxury Elevated Cabin | Sauna • Yoga • Romantic

Luxury Couples Cabin | Hot Tub, Sauna, Soaking Tub

The Blue Door Cabin

Luxury Lakeview Treehouse • Stunning Views • Lake

Secluded Lake View Stargazing

Modern High End Cabin #3 on Horsehead Lake

Yeary Farms Milt's Place with Private Beach!
Frequently Asked Questions
Where is Mississippi River located?
The Mississippi River winds through the central United States, passing through states like Minnesota, Wisconsin, Iowa, Illinois, Missouri, Kentucky, Tennessee, Arkansas, Mississippi, and Louisiana before reaching the Gulf of Mexico. Its banks host diverse communities and landscapes shaped by the river.
When is the best time to visit Mississippi River?
Late spring and early fall are frequently suggested, as temperatures are milder and local events often take place. Summer provides lush scenery but can feel humid, while winter attracts those interested in quieter river landscapes.
What are some things to do near Mississippi River?
You can explore riverfront parks, nature trails, and historic sites, or join boat tours to learn about local wildlife and history. The area also has museums, cultural events, and opportunities for fishing or paddling.
How is the weather near Mississippi River?
Winters are generally cold, ranging from 22–44°F (-5–7°C), while summers reach 83–88°F (28–31°C) with humid conditions. Spring and fall are often recommended for milder temperatures and changing scenery along the river.
Destinations to explore
- Bungalow rentals Mississippi River
- Train rentals Mississippi River
- Rentals with an accessible height bed Mississippi River
- Hostel rentals Mississippi River
- Boutique hotels Mississippi River
- Family-friendly rentals Mississippi River
- Ski-in/ski-out rentals Mississippi River
- Guesthouse rentals Mississippi River
- Rentals with a sauna Mississippi River
- Vacation home rentals Mississippi River
- Boat rentals Mississippi River
- Ranch rentals Mississippi River
- Private suite rentals Mississippi River
- Rentals with lake access Mississippi River
- Rentals with beach access Mississippi River
- Serviced apartment rentals Mississippi River
- Loft rentals Mississippi River
- RV rentals Mississippi River
- Treehouse rentals Mississippi River
- Tent rentals Mississippi River
- Beachfront rentals Mississippi River
- House rentals Mississippi River
- Apartment rentals Mississippi River
- Resort rentals Mississippi River
- Cabin rentals Mississippi River
- Rentals with a soaking tub Mississippi River
- Earth house rentals Mississippi River
- Rentals with an accessible height toilet Mississippi River
- Luxury rentals Mississippi River
- Rentals with breakfast Mississippi River
- Condo rentals Mississippi River
- Tiny house rentals Mississippi River
- Campsite rentals Mississippi River
- Yurt rentals Mississippi River
- Hotel rooms Mississippi River
- Shipping container rentals Mississippi River
- Dome rentals Mississippi River
- Pet-friendly rentals Mississippi River
- Farmstay rentals Mississippi River
- Aparthotel rentals Mississippi River
- Rentals with pools Mississippi River
- Cottage rentals Mississippi River
- Nature eco lodge rentals Mississippi River
- Bed and breakfasts Mississippi River
- Villa rentals Mississippi River
- Chalet rentals Mississippi River
- Houseboat rentals Mississippi River
- Rentals with a hot tub Mississippi River
- Waterfront rentals Mississippi River
- Barn rentals Mississippi River
- Rentals with a kayak Mississippi River
- Townhouse rentals Mississippi River
- Castle rentals Mississippi River
- Things to do Mississippi River
- Cooking Mississippi River
- Landmarks Mississippi River
- Food tours Mississippi River
- Wildlife Mississippi River
- Art workshops Mississippi River
- Cultural tours Mississippi River
- Outdoors Mississippi River
- Things to do United States
- Shopping and fashion United States
- Cultural tours United States
- Museums United States
- Dining United States
- Architecture United States
- Workouts United States
- Art workshops United States
- Flying United States
- Wellness United States
- Food tours United States
- Wildlife United States
- Landmarks United States
- Water sports United States
- Performances United States
- Tastings United States
- Galleries United States
- Cooking United States
- Beauty United States
- Outdoors United States





