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Panama vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Panama

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

  1. Entire rental unit
  2. Panamá
Arias Hab No. 6 Double

Unique architecture in Casco Viejo, entirely renovated very recently. - You have a pool, a rooftop, and your completely private and brand new room. - Two bedrooms with double bed, designer furniture, tv with Netflix, air conditioning, sheets and towels, shampoo, soap, etc. - One amazing bathroom full equiped. - The building with more history of Casco Viejo, given its name after the first president of the republic in 1903, Tomas Arias, who lived here

G$11,446 per night
  1. Entire rental unit
  2. Panamá
Spectacular loft in the center with pool DI7

TOTALLY NEW AND REDECORATED Magazine apartment and completely designed and equipped with swimming pool. You have a pool at the door of the apartment to spend an incredible stay. Master bedroom with king bed and double sofa bed, kitchen, bathroom, very bright, smart tv, etc. ► Silent air conditioning in all rooms. ► Smart TV with 2000 channels in all rooms

G$14,467 per night
SUPERHOST
  1. Private room
  2. Panamá
Habitacion en Ciudad de Panama cerca del metro

Habitación a 2 mins caminando de estación del metro del ingenio, fácil acceso, el apartamento cuenta con garita de seguridad 24/7

G$4,513 per night

Vacation rentals for every style

Get the amount of space that is right for you

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Panama beach vacation rentals

  1. Entire condo
  2. Panamá
Spectacular apartment with roof and Jacuzzi P9
G$17,335 per night
  1. Entire rental unit
  2. Panamá
POOL 3 bedrooms and views to National Theater D3
G$26,845 per night
SUPERHOST
  1. Entire rental unit
  2. Panamá
Excellent Apartment Ocean Front in Panama city
G$17,992 per night
SUPERHOST
  1. Private room
  2. Panamá
Spacious, comfortable with a beautiful view for executives.
G$6,247 per night
  1. Entire rental unit
  2. Panamá
COZY APARTMENT IN PUNTA PACIFICA
G$12,343 per night
SUPERHOST
  1. Hotel room
  2. Bocas del Toro Province
Double Loft Style Bedroom: Great Value
G$11,044 per night
  1. Entire rental unit
  2. Panamá
Apartment in Avenida Balboa city view
G$26,360 per night
SUPERHOST
  1. Entire rental unit
  2. Panamá
105m2 Luxury apartm in Bayfront Tower
G$12,971 per night
SUPERHOST
  1. Entire rental unit
  2. Nueva Gorgona
Oceanfront Tropical Condo With Direct Beach Access
G$11,297 per night
SUPERHOST
  1. Entire rental unit
  2. Rio Hato
Modern loft with ocean and beach views.
G$31,979 per night
  1. Entire condo
  2. Panamá
Beautiful and Central Apartment. Ocean view
G$16,885 per night
SUPERHOST
  1. Entire guest suite
  2. Bastimento
1BD/1BA Suite, Caribbean View, SEA Rm
G$12,552 per night

Panama houses

SUPERHOST
  1. Private room
  2. Panamá
"Allá Mamá" by Tocumen Int'l. Airport
G$2,092 per night
  1. Entire home
  2. Panama City
#1 ALBROOK VILLA SURROUNDED BY NATURAL LANDSCAPING
G$5,021 per night
SUPERHOST
  1. Private room
  2. Bocas del Toro Province
The "Plain Jane" Surfer's Hut; Private Room 1 of 3
G$5,529 per night
SUPERHOST
  1. Private room
  2. Panamá
Pleasant private room in residential house
G$3,138 per night
  1. Private room
  2. Panamá
Kike House
G$3,347 per night
SUPERHOST
  1. Entire home
  2. Pedasí
Casa Pelicano Venao
G$38,494 per night
SUPERHOST
  1. Private room
  2. Panama City
Private Room , 10 minutes from airport
G$3,975 per night
SUPERHOST
  1. Private room
  2. Panamá
Special Tropical Home - Upstairs Bedroom w/Balcony
G$6,067 per night
  1. Private room
  2. Panamá
Cuarto individual lleno de Arte
G$2,092 per night
  1. Entire home
  2. Panamá City
7 small studio apartment with all in albrrok
G$3,347 per night
SUPERHOST
  1. Private room
  2. Santa Catalina
COIBAHOUSE BEACHFRONT GUESTHOUSE-ROOM 1
G$12,552 per night
SUPERHOST
  1. Entire home
  2. Torio
Comfortable, modern house - breathtaking sea view
G$17,783 per night

Panama beach houses

  1. Entire home
  2. Las Tablas
Exclusive Miranda Suites Beach House #2
G$8,513 per night
SUPERHOST
  1. Entire home
  2. Bocas del Toro Province
Purple House 2 - Over The Water Rentals
G$18,619 per night
SUPERHOST
  1. Entire home
  2. Bocas del Toro Province
Abracadabra Bluff Beach- Beautiful Custom Casita
G$24,059 per night
SUPERHOST
  1. Entire home
  2. Vista Mar Golf, Beach & Marina
Luxurious Beach House - Private Pool Golf & Marina
G$106,695 per night
SUPERHOST
  1. Entire home
  2. Bocas del Toro District
Amazing over the water house
G$29,737 per night
SUPERHOST
  1. Private room
  2. Bocas Town
The "Nomad" Surf Shack Private Bath & AC
G$9,862 per night
SUPERHOST
  1. Private room
  2. Bocas del Toro Province
GardenRoomBreeze w/Bocas Beach House side beach
G$5,230 per night
SUPERHOST
  1. Private room
  2. Bocas del Toro Province
oceanfront guesthouse bd
G$11,716 per night
SUPERHOST
  1. Entire home
  2. Costa Esmeralda
Beach House-Ocean View & Rooftop Pool
G$52,301 per night
SUPERHOST
  1. Entire home
  2. Bastimento
Casa del Mar Bastimentos - Oceanfront holiday home
G$27,214 per night
  1. Entire home
  2. Las Tablas
Beach Front House /Pocri/LosSantos/AGUA CALIENTE
G$10,908 per night
  1. Entire home
  2. Las Escobas del Venado
Exclusive villa with infinity pool and direct access to the beach!
G$43,515 per night

Your guide to Panama

All About Panama

A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.

The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.


How do I get around Panama?

Tocumen International Airport (PTY) is the main gateway into Panama, connecting to many destinations in the Americas and Europe. It only takes 20 to 30 minutes to drive to central Panama City, and it’s easy to catch a city bus or hail a taxi. Alternatively, you could rent a car at the airport. Many of Panama’s best-known destinations are easy to reach via public buses and ferries, though if you’re headed into the mountains a short plane ride might be easiest. Buses to destinations across the country depart from the Gran Terminal de Transportes in Panama City. If you’re staying in Panama City, it’s possible to walk to many places within the historic center, and taxis and buses are plentiful throughout the metro area.


When is the best time to stay in a vacation rental in Panama?

The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.

Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.


What are the top things to do in Panama?

Casco Viejo

As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.

Panama Canal

When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.

Bocas Del Toro

Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.