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House vacation rentals in Panama

Find and book unique houses on Airbnb

Top-rated house rentals in Panama

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Home in Bajo Boquete

4.81 out of 5 average rating, 110 reviews

Secluded Riverfront Home - Boquete area with Pool

Rio Escondido is located in the Boquete District near the town of Caldera. This incredible home rests on a bluff overlooking the Chiriqui Nuevo River. The river is about 400 meters from the house. The property is about 30 minutes from the cities of Boquete and David and the town of Caldera is only 5 minutes away. The house has everything you can ask for in a true vacation getaway and the property is a nature lovers dream. Rio Escondido is also a model of Off-Grid living as we are 100% Solar.

Nov 7 – 14

G$16,508 GYD per night

Home in Bocas del Toro District

4.93 out of 5 average rating, 191 reviews

Orange House - Over The Water Rentals

Enjoy golden sunsets across the bay from the Orange House at Over The Water Rentals. Home away from home in a tropical paradise. Relax on your outdoor lounge or explore the bay. The house has snorkel gear, SUP's & kayaks for guests to use for free. Bikes can be rented. Located close to town & airport in a quiet local neighborhood. The house features a king size master bedroom & queen guest room, spacious hot water shower, handmade organic toiletries, fully equipped kitchen & high speed wifi

Jul 9 – 16

G$29,576 GYD per night

Home in Los Algarrobos

4.99 out of 5 average rating, 118 reviews

New house! 5 min from David on the Boquete highway

It’s a new house (Oct 2019) just outside David in Los Algarrobos. Close to the airport, Boquete, Volcan and only 3.5km from the huge new Federal Mall in David. Evening security guards in the subdivision all year. Mountain views, covered parking, seconds from the boquete highway. This immaculate house has all new appliances and furniture, 5G internet, cable tv and Netflix. Your bilingual hosts live next door, the co-host (Grethel) is Panamanian, a lawyer and knows everything about Panama.

Sep 2 – 9

G$15,129 GYD per night

Home in Pedasí

4.94 out of 5 average rating, 113 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Feb 8 – 15

G$35,873 GYD per night

Home in Costa Esmeralda

4.96 out of 5 average rating, 105 reviews

Beach House-Amazing Pool, Surf & Pet Friendly

Majestic Sand! Come relax with the whole family at this piece of paradise. Majestic Sand is located in a private beach community in Costa Esmeralda, San Carlos District, Panama. It is located a few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, Santa Clara and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool with multiple hammocks with views of amazing palm trees.

Oct 31 – Nov 7

G$41,601 GYD per night

Home in Taboga Island

4.96 out of 5 average rating, 140 reviews

Casa Rosie - Taboga dream home

Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Aug 28 – Sep 4

G$50,621 GYD per night

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 196 reviews

Tropical Haven with Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Nov 15 – 22

G$65,577 GYD per night

Home in Playa Venao

4.9 out of 5 average rating, 115 reviews

Beautiful Home Directly on Playa Venao Sleeps 8-10

This is our personal home and we take good care to make sure you thoroughly enjoy your stay! This home is located on the best surfing beach in the entire country. Walk out of your back door onto the sandy beach filled with wildlife and the best beach break for beginners to pros. This home offers luxury accommodations. This home is for families and respectful renters only. We do not accept groups who want to use the home to party.

Aug 1 – 8

G$93,092 GYD per night

Home in El Valle de Antón

4.93 out of 5 average rating, 117 reviews

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Aug 3 – 10

G$23,726 GYD per night

Home in Vista Mar Golf, Beach & Marina

4.88 out of 5 average rating, 224 reviews

Luxurious Beach House - Private Pool Golf & Marina

Vista Mar Golf, Beach & Marina is a gated community with private security, with direct access to a state of the art golf course designed by J. Michael Poellot. It also has marina, heliport, tennis courts, direct private beach access, bars and restaurants. The house comes with an outdoor private pool & hot tub, also a amazing private outdoor kitchen, and an amazing sea view with spectacular sunrises and sunsets.

Dec 1 – 8

G$156,049 GYD per night

Home in Altos del Maria

4.78 out of 5 average rating, 238 reviews

Modern House in Altos del Maria, Panama

Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. It´s a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains.

Aug 10 – 17

G$55,837 GYD per night

Home in Palmira

4.94 out of 5 average rating, 143 reviews

Hacienda Belina - private coffee farm experience

Hacienda Belina is our private family owned coffee farm located in the beautiful mountains of northwestern Panama just on the outskirts of the town of Boquete. My parents live on the property and together we operate this small Hacienda designed to attract avid travelers who are looking for a clean, comfortable, quiet, carefully decorated and authentic place to stay.

Jul 28 – Aug 4

G$21,090 GYD per night

Vacation rentals for every style

Get the amount of space that is right for you

Bungalows

Intimate homes. inviting architecture

Apartments

Convenient locations with everyday essentials

Cabins

Kick off your hiking boots at these rustic lodgings

Popular amenities for Panama house rentals

Free parking on premises

Air conditioning

House rentals with a pool

Home in Panama

4.96 out of 5 average rating, 138 reviews

Villa Isabella in Coronado Beach Panama

Feb 28 – Mar 7

G$74,983 GYD per night

Home in contadora

4.85 out of 5 average rating, 191 reviews

villa in counter, pearls

Sep 30 – Oct 7

G$27,656 GYD per night

Home in Panama City

4.88 out of 5 average rating, 25 reviews

Beautiful house with private pool

May 23 – 30

G$26,974 GYD per night

Home in Playa Mata Oscura

4.92 out of 5 average rating, 25 reviews

Casa De Ola, Jungle Beach Cabin

Mar 16 – 23

G$38,365 GYD per night

Home in Playa Venao

5.0 out of 5 average rating, 15 reviews

Casa Samambaia - sea view tropical paradise w pool

Jun 15 – 22

G$56,807 GYD per night

Home in Playa Bluff

5.0 out of 5 average rating, 15 reviews

Jungle House 100m from the beach

Jun 16 – 23

G$53,864 GYD per night

Home in San Carlos

4.93 out of 5 average rating, 87 reviews

Beach House-Ocean View Rooftop Jacuzzi & Pool

Mar 16 – 23

G$54,708 GYD per night

Home in Gamboa

4.86 out of 5 average rating, 88 reviews

BirdHouse@ Gamboa Panamá Canal

Aug 5 – 12

G$76,308 GYD per night

Weekly house rentals

Home in Paso Ancho

4.87 out of 5 average rating, 130 reviews

Vista El Baru - Volcan, Paso Ancho, Panama

Mar 25 – Apr 1

G$15,734 GYD per night

Home in Bocas del Toro

5.0 out of 5 average rating, 9 reviews

La Casita Barrbra BnB

Jun 21 – 28

G$44,718 GYD per night

Home in Boquete

5.0 out of 5 average rating, 63 reviews

Alba Verde Guest House, Private Vacation Rental

Feb 3 – 10

G$28,742 GYD per night

Home in Santa Catalina

5.0 out of 5 average rating, 24 reviews

Casa Colibrí - modern house in the green

Jun 29 – Jul 6

G$28,803 GYD per night

Home in Boquete

5.0 out of 5 average rating, 12 reviews

Caturra Casita @ Finca Panda

Mar 16 – 23

G$64,138 GYD per night

Home in Torio

5.0 out of 5 average rating, 13 reviews

Ideal Creative Retreat Immersed in Forest

Jan 3 – 10

G$23,592 GYD per night

Home in Corregimiento de Isla Grande

4.96 out of 5 average rating, 83 reviews

Puntita Manzanillo, fantastic sea and jungle

Feb 11 – 18

G$105,008 GYD per night

Home in Nueva California

5.0 out of 5 average rating, 10 reviews

Spacious 3 bedroom house in Volcan cloud forest

Aug 29 – Sep 5

G$20,729 GYD per night

Private house rentals

Home in Bastimento

4.84 out of 5 average rating, 44 reviews

Bay Of The Floating Palms - Beach Front Home

Jun 6 – 13

G$58,427 GYD per night

Home in Panamá

4.95 out of 5 average rating, 44 reviews

Cozy cabin in the mountains of Cerro Azul

May 13 – 20

G$40,005 GYD per night

Home in Cacique

5.0 out of 5 average rating, 18 reviews

El Paraiso

Nov 15 – 22

G$59,721 GYD per night

Home in Nueva Gorgona

5.0 out of 5 average rating, 26 reviews

Cozy beachfront cottage

May 20 – 27

G$25,369 GYD per night

Home in Anton Valley

5.0 out of 5 average rating, 16 reviews

Modern Duplex in El Valle de Anton

May 30 – Jun 6

G$13,640 GYD per night

Home in Veraguas Province

4.86 out of 5 average rating, 37 reviews

Casa Puerta al Mar with amaizing view, Morrillo

Jan 25 – Feb 1

G$29,140 GYD per night

Home in Alto Quiel

4.86 out of 5 average rating, 14 reviews

Casita Colibrí - with beautiful mountain views

Jun 20 – 27

G$14,459 GYD per night

Home in Río Hato

4.86 out of 5 average rating, 58 reviews

Poolside Paradise in Santa Clara

May 4 – 11

G$29,769 GYD per night

Destinations to explore