Apartment vacation rentals in Panama

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Top-rated apartment rentals in Panama

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Top guest favorite

A modern living space features an open kitchen with wooden cabinetry and a dining area. A curved gray sofa is complemented by yellow pillows, positioned next to a round coffee table. Natural light streams through blinds, illuminating the minimalist decor.

Apartment in Panamá

5 out of 5 average rating, 80 reviews

New apartment on 50th Street

Enjoy a stylish experience at this centrally-located place. Direct access to bus lines and the Metro. Close to tourist sites and steps away from a variety of restaurants, grocery store, nightlife, casinos and blocks from the coastal strip, Iglesia del Carmen, and Parque Urraca. The old town is just minutes away by Uber. Close to shopping area. Soho Mall, Multi Plaza Mall, and Albrook Mall. Relaxing swimming pool for adults and children. Bar and restaurant, co-working, gym. You'll have a great time.

Top guest favorite

Apartment in Panama City

5 out of 5 average rating, 33 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Guest favorite

The balcony features a round wooden table set with a glass candle holder, surrounded by wicker chairs. A panoramic view of the water and city skyline extends in the background, while colorful market lights add a subtle charm along the railing.

Apartment in Panama City

4.96 out of 5 average rating, 28 reviews

The Captain's Canal View Penthouse

Experience luxury & stunning views in the Captain's Canal View Penthouse, owned by a Panama Canal Pilot & designed for ship-watching. This one-of-a-kind apartment offers panoramic vistas of Panama Bay's cityscape on one side and the bustling canal on the other. Located on the Amador Causeway, you're steps from vibrant restaurants, bars, & the cruise ship terminal. Your stay includes exclusive access to StandUp Panama, where you can paddle at sunrise on the canal for an unforgettable experience.

Superhost

A cozy living area features a comfortable blue sofa against an original brick wall, complemented by a round mirror. A small kitchen area with white cabinetry and modern appliances is visible. A decorative coffee table and elegant chairs complete the inviting space.

Apartment in Panamá

4.81 out of 5 average rating, 150 reviews

The Penthouse Annex

Inspired by Panama's rich history with France and located in one of the oldest watch towers in Panama, this chic apartment combines original features of this historically important building with the elegance and style of Europe. Perfectly situated to indulge in the restaurants, cafes, museums and boutique stores of Casco Viejo, and equipped with everything you expect from a home-from-home base, the annex is the perfect combination of comfort and style for couples and small groups of friends.

Guest favorite

A hammock sways gently between posts, overlooking calm waters that reflect a clear blue sky. In the distance, a lush island is visible, providing a picturesque backdrop. The green grass leads up to the water's edge, creating a serene outdoor space.

Apartment in Juan Gallego

4.85 out of 5 average rating, 126 reviews

Pebos Reef, apt #2, Amazing views !!

This spectacular beachfront property is ideally situated with an incredible view of neighboring islands, fishing friendly waters, and mesmerizing snorkeling spots for children and adults to enjoy. Monkey greetings from the jungle adjacent, octopus and colorful native fish inhabited waters, and lazy bear sloth sightings are all part of your daily experiences here at Pebos Reef! If you are lucky you will even see dolphins from the terrace ! A terrace on the sea is all you need.

Superhost

An open living space features a large gray sectional sofa paired with a round wooden coffee table. A patterned rug lies beneath, complementing the light wooden flooring. The kitchen area is visible in the background, showcasing modern appliances and a breakfast bar with stools.

Apartment in Panamá

4.94 out of 5 average rating, 152 reviews

Cozy 2 Bedroom w/ Splash Pool

Our place is a 3-story apartment located on the quiet side of Casco Viejo. It has a very private feel to it, which allows for an incredible afternoon of sunbathing or bbqing on our private rooftop. The splash pool allows for a refresh and fits 2 people at a time. This place has so much character from with original exposed stone walls, to the sweeping view of the Arto Chato ruins. It also has a great work space, all the necessities to stay in and cook, watch a movie, etc.

Guest favorite

A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.

Apartment in Panamá

4.98 out of 5 average rating, 143 reviews

Escape to the Heart of Casco with a Private Balcony

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favorite

Apartment in Panamá

5 out of 5 average rating, 14 reviews

Stylish Casco Antiguo Apt • Pool & Parking

Stay in a stylish modern apartment just steps from Panama City’s historic Casco Viejo and the scenic Cinta Costera Recently decorated with a contemporary design, it’s perfect for relaxing or working remotely with fast WiFi. Guests enjoy access to a rooftop with panoramic views and pool, a coworking space, and private parking. Surrounded by top restaurants, bars, shops, and major attractions, it’s the ideal base to discover the magic of Panama.

Guest favorite

A welcoming living area features modern furnishings and vibrant artwork. A round wooden coffee table is accompanied by a cozy sofa and armchairs. Natural light pours in from large glass doors leading to a balcony, while a plant adds a touch of greenery.

Apartment in Panamá

4.95 out of 5 average rating, 118 reviews

Luxury apartment in Panama, ocean view

Located in San Francisco, one of Panama's exclusive areas par excellence, where gastronomy, history, modernity, and entertainment magically combine. Wonderful location near must-see destinations, gym, swimming pool, co-working, pet spa, and terrace. Parking is charged. Modern and functional, this apartment features a queen-size bed, fully-equipped kitchen, Wi-Fi, TV, a spectacular balcony with ocean views, laundry center, and sofa bed.

Top guest favorite

An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.

Apartment in Panamá

4.97 out of 5 average rating, 114 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favorite

A cozy living area features a light-colored sofa facing a wall-mounted television. A round table is set in front, and woven placemats add texture. Large windows showcase city views and provide natural light, while a bedroom is visible in the background, showcasing a spacious bed.

Apartment in Panamá

5 out of 5 average rating, 112 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Superhost

A tranquil pool area is framed by lush palm trees and vibrant bougainvillea flowers. Sun loungers are positioned nearby, offering views of the ocean. The clear water of the pool reflects the sunny sky, creating a relaxing outdoor environment for guests.

Apartment in Veracruz

4.9 out of 5 average rating, 142 reviews

Studio on a beachfront property near Panama city

The village name is Veracruz, this is a small fishing village located at the pacific ocean. It´s 20 minutes driving to Panama city. There are public buses or taxis available 24/7 The studio is located in a very quit área of Veracruz. And it´s an ideal place to retrait in the evening and enjoy the tranquility. On the beach of Veracruz are several nice restaurants and bars with live music located