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Guesthouse vacation rentals in Panama

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Top-rated guesthouse rentals in Panama

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite
A charming cottage with a red metal roof is surrounded by lush greenery and colorful flowers. A few small trees and plants frame the image, highlighting the tranquil garden setting and the natural beauty of the hillside location.
Guesthouse in Los Naranjos
4.93 out of 5 average rating, 233 reviews

Sunshine Cottage at Finca Katrina

Sunshine Cottage is a little cottage in the back garden of Finca Katrina. It is set on a hill with views of Palo Alto and Jaramillo with a coffee plantation in the foreground. There is a full (double) bed, room to hang your clothes and to store your belongings. You have a small fridge, toaster oven, sink, coffee maker, and cupboard space for food, but no stove top. If you are looking for more bedrooms, there are additional units on Finca Katrina that compliment Sunshine Cottage. Send us a note!

Top guest favorite
The living area features large glass doors that invite natural light and views of the garden. Indoor plants enhance the space, and a cozy seating arrangement includes a sofa and eclectic chairs. A workspace with a desk and lamp is positioned to the side.
Guesthouse in El Valle de Antón
4.99 out of 5 average rating, 103 reviews

Spacious Casita with Bamboo View

Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Top guest favorite
A traditional bohio with a thatched roof is set amidst lush greenery. A pathway leads to a serene pool, flanked by vibrant tropical plants and flowers. The surrounding landscape features distant mountains, softly illuminated by the warm light of dusk.
Guesthouse in El Valle de Antón
4.98 out of 5 average rating, 53 reviews

The Retreat in El Valle - Garden House

Welcome to your serene retreat in El Valle, Panama! Nestled amid lush nature, our two-bedroom casitas offer a peaceful escape with breathtaking views, exotic wildlife, and flora. Each casita features a queen bed, choice of king or twin beds in the second room, a small fridge, coffee station, Wi-Fi, and large terrace. Enjoy the shared pool, meditation and healing sessions by appointment, and explore world-class hiking nearby. Just a short walk to restaurants and El Valle’s famous artisan market!

Top guest favorite
A two-story guest house is situated next to a curved pool, surrounded by lush greenery and tall palm trees. Large windows reflect natural light, and a tiled roof complements the tropical setting. The pool features varying depths and a smooth edge that blends into the landscape.
Guesthouse in San José
4.97 out of 5 average rating, 31 reviews

Guesthouse in Punta Barco Resort

Guest house in Punta Barco Resort with access to 2 pools and private beach (nearby Coronado). The separate entrance accessible two-story guest house has both a sleeping area (downstairs) and a living area (upstairs). The 1st pool is right in front of your guest house. The 2nd communal resort pool with stunning sea views is located next to the resort's private beach within the resort complex and can be reached in a short drive by car. The use of the beach depends on the weather and the tides.

Top guest favorite
A serene view from the guesthouse showcases a private balcony with two chairs and a small table, positioned before lush greenery and distant mountains. The inviting landscape is framed by the sliding glass doors, enhancing the connection to nature.
Guesthouse in Torio
4.91 out of 5 average rating, 140 reviews

Torio guesthouse with panoramic view

Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Guest favorite
A private swimming pool with a waterfall is surrounded by lush greenery, providing a tranquil setting. A thatched-roof structure is visible nearby, creating an inviting space for relaxation. Colorful flowers and plants enhance the outdoor area, making it suitable for leisurely outdoor dining.
Guesthouse in Rio Hato
4.89 out of 5 average rating, 106 reviews

Sustainable Guest house with Pool in Rio Hato

Discover Rancho Ahome, a serene 2BR 1Bath guesthouse in Rio Hato. Escape to tranquility, 5 mins from stunning beaches, and enjoy our private pool with a waterfall. Immerse in nature on our sustainable farm, home to fruits, rabbits and chickens. Perfect for those seeking peace and an eco-friendly retreat, Rancho Ahome offers a blend of comfort and adventure amidst breathtaking landscapes. Experience a peaceful sanctuary that’s close to nature yet filled with comfort. We are pet friendly.

Guest favorite
The Sky Cabin is surrounded by vibrant tropical foliage and flowering plants, showcasing a colorful exterior. A stone pathway leads to the cabin, with a covered outdoor area visible, ideal for enjoyment in the garden's serene environment.
Guesthouse in La Ermita de San Carlos
4.97 out of 5 average rating, 124 reviews

Rural+comfy: AC, WiFi, hot water, pool, private

The Sky Cabin is part of 5 cabins “A Piece of Paradise” With registration in the Panamanian Tourism Authority Bureau. ✸ Ideal for a couple or a single person ✸ Outdoor dining area and kitchen ✸ Spacious terrace with a hammock ✸ Very quiet neighborhood ✸ Private and public transportation available, just ask and we will help you ✸ 7-10 minutes, by car, from Playa La Ermita and 10 minutes from Playa El Palmar (great spot for surfing) ✸ Breakfast for an additional $7.00, for each guest.

Top guest favorite
Guesthouse in Panamá
4.76 out of 5 average rating, 245 reviews

Garden Cottage in Panama City

Welcome to our charming cottage, an oasis in the heart of the city, ideal for nature lovers and comfort seekers. Located in a central area, this retreat offers the perfect combination of tranquility, comfort, and proximity to Panama's main attractions. Enjoy the balance between urban life and the serenity of the natural surroundings. It features a private entrance, a spacious garden, a barbecue area, and a terrace where you can relax and connect with nature.

Superhost
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guesthouse in Panamá Oeste
4.8 out of 5 average rating, 102 reviews

Mountain House in Panama

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and with spectacular views, here you can breathe pure air and gaze at the stars. ✔️ Great for couples, families or adventurers. Nearby ✔️ trails, rivers and viewpoints. ✔️ Comfortable and equipped spaces for your comfort. - Capacity of 4 people - Possibility of having 1 double bed and 2 singles or 4 single beds - Discount from two nights

Guest favorite
A small balcony is visible, featuring a round wooden table set with two white chairs. The view shows calm, clear waters with a vibrant yellow bungalow in the background. Light glistens off the water, creating a serene atmosphere.
Guesthouse in Bocas del Toro
4.92 out of 5 average rating, 63 reviews

The Boat House in Big Bight

Come relax in this peaceful over the water ECO bungalow on Isla Colon, on a coral reef 15 minutes away from town BY BOAT ONLY.. See lots of stars in the sky, tons of sea life & stunning sunsets from your balcony! Enjoy Starfish Beach, just a 5 minute boat ride away. Red Frog Beach, Playa Bluff, Zapatillas, & much more while you're here in Bocas Del Toro! (Kitchen is provided with basic cooking essentials & bathroom with basic personal items).

Guest favorite
The property is illuminated at night, showcasing a spacious terrace with comfortable furniture. Soft lighting highlights the structure's features, while stairs lead to the lower level. A serene atmosphere is created by the surrounding trees and dark sky.
Guesthouse in Mariato
4.96 out of 5 average rating, 82 reviews

Beachfront Nature Rentals, Full floor Studio

At Beachfront Nature Rentals, we have a 1km beautiful sandy beach. STARLINK internet. Peace & Quiet. 4 wheel drive car is not required. Soft rhythmic sound of the waves. Every week; new birds, turtles nesting, dolphins, whales or monkeys. See the stars without light pollution. Ocean is perfect for swimming and sometimes body-boarding. Swim in our pool anytime you like. If you surf, we have walking or driving access to a surfing beach.

Guest favorite
A cozy sleeping area features a wooden bed dressed in a floral-patterned quilt and decorative pillows. Soft lighting is provided by bedside lamps, while light filters through a window adorned with sheer curtains, enhancing the calming atmosphere of the room.
Guesthouse in Panamá
4.87 out of 5 average rating, 67 reviews

Private guest house in Ancón

Enjoy the simplicity of this cozy, quiet and central accommodation. Close to sights such as the Panama Canal Administration building, Amador Causeway, Albrook Mall, and several restaurants. Personally decorated to provide comfort... large windows in the bedroom provide natural lighting and a view of the garden and green area through the windows; yet it maintains the desired privacy and tranquility.

Popular amenities for Panama guesthouse rentals

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