
Guesthouse vacation rentals in Panama
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Top-rated guesthouse rentals in Panama
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Sunshine Cottage at Finca Katrina
Sunshine Cottage is a little cottage in the back garden of Finca Katrina. It is set on a hill with views of Palo Alto and Jaramillo with a coffee plantation in the foreground. There is a full (double) bed, room to hang your clothes and to store your belongings. You have a small fridge, toaster oven, sink, coffee maker, and cupboard space for food, but no stove top. If you are looking for more bedrooms, there are additional units on Finca Katrina that compliment Sunshine Cottage. Send us a note!

Spacious Casita with Bamboo View
Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

The Retreat in El Valle - Garden House
Welcome to your serene retreat in El Valle, Panama! Nestled amid lush nature, our two-bedroom casitas offer a peaceful escape with breathtaking views, exotic wildlife, and flora. Each casita features a queen bed, choice of king or twin beds in the second room, a small fridge, coffee station, Wi-Fi, and large terrace. Enjoy the shared pool, meditation and healing sessions by appointment, and explore world-class hiking nearby. Just a short walk to restaurants and El Valle’s famous artisan market!

Gamboa Toucan Apartment casa # 126
Welcome to Gamboa! Only 35 minutes from downtown Panama, Gamboa. Situated in Soberanía National Park and on the shores of the Panama Canal, is a Mecca for Birdwatchers and Nature enthusiasts! Watch the wildlife right from the backyard of your fully equipped apartment. Feel the magic songs of thousands of birds welcoming the twilight of sunrise and dusk in this century old community. Easily explore wildlife on trials through the surrounding old growth jungle and by boat on the Panama Canal.

Torio guesthouse with panoramic view; Kokomo
Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Beachfront Nature Rentals, Full floor Studio
At Beachfront Nature Rentals we have a 1km beautiful sandy beach. STARLINK, Solar power, Peace & Quiet. 4 wheel drive car is not required. Soft rhythmic sound of the waves. Every week; new birds, turtles nesting, dolphins, whales or monkeys. See the stars without light pollution. Ocean is perfect for swimming and body-boarding. Swim in our pool anytime you like. We have walking or driving access to a surfing beach. For DIGITAL NOMADS, a desk, good wifi, work on the terrace, Rancho or beach.

Casita Verde 411
Your private jungle hideaway by the ocean. Wake up to the sound of waves and tropical birds, just a 3-min walk from the surf. Step outside into lush greenery, slow down, and feel more present. A quiet place to surf, relax, and reconnect – far from crowds, surrounded by nature and ocean. Spend your mornings in the water, unwind in the hammock, and enjoy stargazing at night. Perfect for longer stays, remote work, or anyone looking for a slower, grounded way of living.

Mountain cabin with private pool
Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Possibility of having 1 double bed and 2 single beds or 4 single beds. - Discount for two nights or more.

Small House/Rural/AC, WiFi, pool, hot water
The Small House is part of 5 cabins called “A Piece of Paradise” plus the House where the hosts live; Registered in the Panamanian Tourism Authority Bureau. ✸ Ideal for a couple or a single person ✸ Outdoor dining area and hammock ✸ Very quiet neighborhood ✸ Private and public transportation available, just ask and we will help you ✸ 7-10 minutes, by car, from Playa La Ermita and 10 minutes from Playa El Palmar (great spot for surfing)

Private guest house in Ancón
Enjoy the simplicity of this cozy, quiet, and centrally-located accommodation. Close to places of interest such as the Panama Canal Administration building, Amador Causeway, Albrook Mall, and several restaurants. Personally decorated to provide comfort... large windows in the bedroom provide natural lighting and a view of the garden and green area through the windows; yet it maintains the desired privacy and tranquility.

Flor del Aire Cabin
Welcome to our Flor del Aire cabin. A private and cozy retreat, for up to 3 people. The cabin is surrounded by a large garden where you can enjoy the local biodiversity. We have a well-equipped kitchen and shower with hot water. *Private parking. *Wi-Fi-free space, an ideal opportunity to disconnect. For those who need Wi-Fi there is an excellent coffee shop just a few meters away. *We are pet friendly.

Boho Studio - Private Terrace 9 km from airport
Perfect for 1–2 guests, Wifi, quiet terrace, separate room, has A/C, and its small bathroom. Located near Tocumen International Airport, 10 to 13 minutes by car. The Studio is close to 2 Shopping Centers, Metromall and Los Pueblos OUTLET. The residential area is safe to walk, organized and clean streets. We have the Cerro Viento Metro station outside in Metromall.
Popular amenities for Panama guesthouse rentals
Family-friendly guest house rentals

Unique find: central+urban+ huge green yard+safe

Reef to Ridge Island Living - 2 Private Casitas

Rustic Private Studio Near Downtown

Bocas Bay Lodge - Luxurious!

A Remote Paradise in nature - Ocean View

Smart Stay by SS • Budget Studio 5+ Airport & Mall

Beautiful Casita, few steps from La India Dormida.

A small apartment-style annex
Guest house rentals with a patio

Private Garden Suites

Cozy cabin w/ Queen Bed & ensuite 10 mn from Beach

Studio with Pool Near Beaches in Bocas del Toro

Villa Alber Mari

(3) The Captain's House - San Fran Room

Tex-Mex Escape #2 | Garden & Walk to Torio beach

A charming spot in La Chorrera

Centrally located cabin in El Valle de Antón, Panama
Guest house rentals with a washer and dryer

Beautiful Casita-Paradise in Panama, New Gorgona

Q&B Inn Cozy One-Room Apartment #2

Casa Tropical Boquete, Duplex #1 2R /2BR

Pool House with Shared Pool Access

Peaceful Contadora Island Guest Home w/Garden View

Saboga Island Beachfront Garden Suite | 6 guests

Private cabin and CasaMomote river, Loma Limón.

08-Casita Colibri, new 2025. Near Beach, big pool!
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