
Mansion vacation rentals in Panama
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Panama
Guests agree: these mansions are highly rated for location, cleanliness, and more.

Spacious, Over the Water Home with Plunge Pool
Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Stylish & Quiet ~ Breathtaking Laguna Views ~Pool
➡️ The highest rated w more than 60 reviews! ⬅️ Welcome to "The Gliding Damselfly," the MOST stylish 4BR 4Bath flat nestled in the majestic Buenaventura, perfect for escaping city crowds and enjoying mesmerizing views, stunning beaches (5 mins), and lavish pools (2 mins). Explore the area and its exciting attractions, and then retreat to the breathtaking sanctuary that will leave you in awe. ✔ 4 Comfy BRs ✔ Open Design Living ✔ Full Kitchen ✔ Terrace ✔ Smart TVs ✔ Fast Wi-Fi See more below!

Spacious 4Br Beachside Getaway at Playa Escondida
Escape to Playa Escondida Resort & Marina for the ultimate luxury getaway. Our 4Br beachfront apartment is ideal for families and friends seeking relaxation in the Caribbean Sea. Indulge in plush rooms, white sand beaches, and unforgettable sunsets. Our fully equipped apartment provides everything you need for an exceptional stay, and our unparalleled service ensures you'll never want to leave. Best of all, it's just an hour away from Panama City. Book now for a truly unforgettable experience.

Costa Blanca Beach & Golf Villa by Decameron
Spacious Villa with Pool, Golf Views & Beach Access Relax in this stylish 4-bedroom villa overlooking the 7th putting green of Mantarraya Golf Course. All on one level, it offers 250 sq m of comfort, with en-suite bathrooms and space for up to 12 guests. Wow ! - Private 15 m pool with shallow area - 15-minute walk to Pacific beach - Access to Owners Beach Club (restaurant + parking) - Peaceful golf course setting Perfect for families, groups, or golf lovers seeking sun and serenity.

OceanView-Rooftop Jacuzzi&Pool | Concierge Service
Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

Beach House with Pool/Gazebo in Punta Chame!
"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Tropical Haven with Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Private House | Beach | Quiet Stays | Wi-Fi | A/C
Cozy & comfy villa with great illumination and natural ventilation located in the Playa Blanca Beach & Lagoon complex in Rio Hato, Cocle just 10 minutes away from Scarlett Martinez International Airport and 90 minutes from Panama City. Playa Blanca is an exclusive tourist residential beach complex with villas, apartments, big lush green areas, the largest pool in Central America, beach club, Playa Blanca Hotel Resort and much more.

Penthouse Deluxe, 360º views and glass pool
Welcome to a luxurious penthouse in the heart of Panama City's Old Town, where comfort and conviviality merge to offer you an unparalleled stay! With four private bedrooms, capacity for eight guests, and 300 square meters of elegance, enjoy a terrace with a glass-enclosed pool and 360° views of the sea and skyline. Bright spaces, impeccable design, and a comfortable, fully-equipped environment.

#1 Villa with a swimming pool, jacuzzi, pool table, and ping pong.
Spectacular villa a few minutes from the beach by car, super spacious, ideal to share with family, friends or corporate meetings. The property is full of surprises and with many things to do including its swimming pool, jacuzzi, pool table, ping pong table, domino table, hammocks, large green areas, gas BBQ, variety of board games and a fully equipped kitchen.

Modern | Steps to Beach Club & Shops | Sleeps 10
• Beautiful design • Excellent location • Steps to the La Mansa Beach Club! • Spacious & luxurious • Luxury Bedding • 75 inches TV • Beautiful views! • Half a block from restaurants & convenience store! • Fully equipped • High speed internet • Buenaventura, best luxury beach resort in Panama
Popular amenities for Panama mansion rentals
Luxury mansion rentals

Villa Solara 5 - Luxury 5 Bedroom Pool Villa

Playa Escondida ocean and mountain view

Beach House Where Emy

Playa Escondida with the Best Direct Ocean View

Hacienda La Perezosa in Cerro Azul

Villa Papagayo, Morrillo Beach, Veraguas

Casa Vida, Breathtaking Ocean View Villa

Modern Luxury Beach Front House in Coronado
Pet-friendly mansion rentals

Welcome to our house in Playa Corona

Lovely 4 Bedroom Condo with Pool - Punta Pacifica

Laguna Fun and Sun: Your Escape Awaits

Charming house with beach access

Wonderful House with Terrace and Ocean View

Ocean, BBQ & marina - Playa Escondida Resort

Exclusive apartment steps from the sea in Puntarena

Cerro Azul, Country House with Heated Pool.
Mansion rentals with a pool

Private Beachfront Getaway

Nice duplex house with a swimming pool.

Villa GiGi - Beach Home Panama Santa Clara

Buenaventura | Luxury Beach Apartment | Panama

Beach apartment in BUENAVENTURA

Playa Escondida, luxury ocean view apartment

Lovely Beachfront Condo at Ensenada Beach

4-bed cabin - heated pool - billiards
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