Mansion vacation rentals in Panama

Spacious, Over the Water Home with Plunge Pool

Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.

Costa Blanca Beach & Golf Villa by Decameron

Spacious Villa with Pool, Golf Views & Beach Access Relax in this stylish 4-bedroom villa overlooking the 7th putting green of Mantarraya Golf Course. All on one level, it offers 250 sq m of comfort, with en-suite bathrooms and space for up to 12 guests. Wow ! - Private 15 m pool with shallow area - 15-minute walk to Pacific beach - Access to Owners Beach Club (restaurant + parking) - Peaceful golf course setting Perfect for families, groups, or golf lovers seeking sun and serenity.

Spacious House | Garden and Terrace | Pet Friendly

Discover the pleasure of staying in a private, elegant, and light-filled villa within the exclusive Playa Blanca Beach & Lagoon. Start your day with the tropical breeze on the terrace, relax by the pool, and enjoy a short 10-minute walk to the beach. Perfect for families and travelers seeking rest, security, and resort-style comfort. Ideally located 10 minutes from Scarlett Martínez Airport and 2 hours from Panama City, it's the perfect place for an unforgettable getaway by the sea.

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Beautiful House in Panama w/ King Beds + Pool

Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Mountain retreat

Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Tropical Haven with Pickleball/Yoga Platform

Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Rustic family mountain home - 5 min walk to town!

Rustic family home with exquisitely landscaped garden complete with bridge over natural stream. Outdoor chill out space with barbecue and terrace under roof with hammocks on one side of the house, and a pergola with lounge area and gas grill on opposite side of the house. Centrally located to main attractions, only a 7 minute walk to the main market. Peaceful, relaxing refuge surrounded by views of nature and the cloud forest.

Coronado. Bright pool and jacuzzi, entire house

Have fun with your whole family in this family and fun space within Coronado with security gate. The house has a beautiful bright swimming pool with a beach, a jacuzzi without a heater accompanied by its kiosk and barbecue. The house has 4 bedrooms and 4 remodeled bathrooms 2 bedrooms have pool access Modern kitchen and spacious dining room Close to the beach, restaurants, and supermarkets

#1 Villa with a swimming pool, jacuzzi, pool table, and ping pong.

Spectacular villa a few minutes from the beach by car, super spacious, ideal to share with family, friends or corporate meetings. The property is full of surprises and with many things to do including its swimming pool, jacuzzi, pool table, ping pong table, domino table, hammocks, large green areas, gas BBQ, variety of board games and a fully equipped kitchen.

Modern | Steps to Beach Club & Shops | Sleeps 10

• Beautiful design • Excellent location • Steps to the La Mansa Beach Club! • Spacious & luxurious • Luxury Bedding • 75 inches TV • Beautiful views! • Half a block from restaurants & convenience store! • Fully equipped • High speed internet • Buenaventura, best luxury beach resort in Panama