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Mansion vacation rentals in Panama

Find and book unique mansions on Airbnb

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Popular amenities for Panama mansion rentals

Luxury mansion rentals

Guest favorite
Villa in Bocas del Toro
5 out of 5 average rating, 64 reviews

Casa del Mar - eco aqua villa

EsterRating, 5 stars1 month ago
Julia’s place is an absolute gem, nestled in the calm waters of the Caribbean Sea at the southern tip of Isla Cristóbal—about a 30-minute boat ride from the main island, Isla Colón. From the moment we arrived, we felt like we were stepping into a unique off-grid paradise. The house itself is self-sustaining, powered by solar energy and using filtered rainwater (which, by the way, tastes amazing!). While there’s no air conditioning, there are plenty of fans to keep the air moving. The views from the house are absolutely stunning. In the mornings, dolphins often patrol the area like local marine police, and right beneath the house, we saw massive snappers swimming in the clear waters. If you paddle out into deeper water by kayak or paddleboard, you’ll likely spot graceful rays gliding beneath you—an unforgettable experience. Victoriano, a local caretaker, was extremely helpful on the property and in surrounding areas and guided us on a hike to see the sloths and the monkeys.
Guest favorite
Cottage in Panama City
5 out of 5 average rating, 19 reviews

Hacienda La Perezosa in Cerro Azul

TeddyRating, 5 stars1 month ago
Very well maintained and clean. Perfect spot for a relaxing time with ample amenities and service staff. Will definitely repeat!
Superhost
An infinity pool is framed by lush greenery, providing a serene view of the beach and ocean. A seated sculpture adds a unique touch to the pool deck, while palm trees surround the area, enhancing the tranquil atmosphere.
Villa in Saboga
4.75 out of 5 average rating, 12 reviews

Casa Laguna - luxury beach front house with pool

AmyRating, 5 stars3 months ago
We had an amazing stay! The place was beautiful, remote, surrounded with wildlife, gorgeous beaches, gear to use, great pools. Hosts were always available to answer our questions, give us rides, connect us with boats, fix things that needed fixing. The house space was perfect for our group of 7, including 4 kids! We did bring a bunch of food from the mainland, which was a good idea. Local market is limited and the nice restaurant just down the beach was good but expensive for regular meals. Zully was available to cook for us and her cooking was outstanding! Matthias and his local manager were very helpful and friendly. We had a beautiful experience and the house and surroundings were wonderful. Highly recommended!
Top guest favorite
Condo in Maria Chiquita
5 out of 5 average rating, 39 reviews

Playa Escondida. Apartment with ocean views.

FelixRating, 5 stars4 weeks ago
Great location, clean, well furnished, amazing host. I will definitely stay here again.
Guest favorite
A sandy beach area features thatched umbrellas providing shade over rows of lounge chairs. A palapa-style structure is visible in the background, enhancing the tropical setting. The calm sea and blue sky create a serene atmosphere, inviting guests to relax by the water.
Villa in Rio Hato
4.91 out of 5 average rating, 58 reviews

Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

Elizio (Bo)Rating, 5 stars1 week ago
It is a beautiful villa home in beautiful Buenaventura, Rio Hato. Very nice ammenities in the home with a wonderful backyard and pool as well. Both Philip and his property manager, Olga, were very responsive and helpful when we had questions or concerns. It has a few restaurants and a shoppette inside the resort. There is also a very large Super99 grocery store and others stores a 10 min drive outside the resort. All in all, this was a wonderful property and stay for our 8-member family group. Thank you!
Top guest favorite
An outdoor gathering space features a fire pit with flames gently dancing above stone, surrounded by wooden seating. A private pool rests in the background, complemented by lounge chairs and vibrant green landscaping, creating a serene retreat for leisure and relaxation.
Home in Rio Hato
4.95 out of 5 average rating, 37 reviews

Villa Santorini | White Beach

VirginiaRating, 5 stars1 week ago
The cozy house, perfect for a group of friends with their families, each room has its own bathroom and therefore we all had enough privacy. The spacious common areas are ideal for children, with all the amenities, the beach is super close... We'd go back
Top guest favorite
A comfortable media room features plush leather seating equipped with built-in cup holders. A large screen is positioned on the opposite wall, surrounded by soft lighting. Natural light enters through expansive windows, offering views of greenery outside, enhancing the inviting atmosphere.
Villa in Panamá
4.98 out of 5 average rating, 53 reviews

Breathtaking Views Mansion w/King Beds

PavanRating, 5 stars3 weeks ago
Its a 5 star house. The house is way bigger than what photos suggest. It can easily fit in 10 people. It is in a very safe neighborhood and close to great restaurants and bakery. It also has good India mart close by if you need any Indian provisions. House all the amenities you need. Pool, garage, big grill, nice kitchen, theatre room with pool table and a yoga place. The only part of the house that we could not get to enjoy is the golf area. I wish we had more time at the house. Will definitely recommend the house. Also Bradley was very responsive.
Guest favorite
A spacious dining area is defined by a large wooden table surrounded by woven chairs. Expansive glass windows offer a view of the outdoor deck and the serene surroundings, with soft evening light filtering through, highlighting the natural tones of the furniture.
Home in Bocas del Toro
4.92 out of 5 average rating, 25 reviews

Architectural Waterfront Home - "Casa Comunal"

FrankRating, 5 stars4 months ago
Fantastic place, the sea is your backyard. Monkeys, tracking, squirrels, and surfers on the waves passing by. Great house, minimalist but very nice with various hangouts. Keep in mind that it can be warm in the house and that insects can easily enter....but there is something great about that.

Pet-friendly mansion rentals

Top guest favorite
The outdoor area features a large swimming pool surrounded by lounge chairs, with a separate jacuzzi nearby. Inside, a game room comprises a pool table and a ping pong table, with expansive glass doors allowing natural light and views of the greenery.
Villa in Costa Esmeralda
4.97 out of 5 average rating, 95 reviews

#1 Villa with a swimming pool, jacuzzi, pool table, and ping pong.

MarubyRating, 5 stars1 month ago
The house was really excellent, they were always attentive to making sure we were comfortable. Everything is clean, I recommend it. It was a wonderful weekend.
Guest favorite
A spacious house is surrounded by lush greenery, featuring a large private swimming pool that reflects the clear sky. Outdoor seating areas are visible, including a sunlit terrace adorned with a hammock, and a trampoline can be seen in the nearby yard.
Villa in San José
4.83 out of 5 average rating, 72 reviews

25% OFF The Family Mini Resort House @Punta Barco

ErikaRating, 5 stars3 weeks ago
The place was really good, but some details were missing, 1 air conditioner didn't work and several bathroom lights were burnt out, but otherwise everything was fine
Guest favorite
An inviting outdoor kitchen area equipped with a grill and dining set overlooks a lush garden. A cozy indoor living space features a plush sofa and a large TV. The private pool, framed by lounge chairs and greenery, offers a tranquil oasis for relaxation.
Condo in El Chirú
5 out of 5 average rating, 23 reviews

Laguna Fun and Sun: Your Escape Awaits

AlyseRating, 5 stars3 weeks ago
The stay was amazing, we enjoyed it from start to finish, surely our host has experience in hospitality because everything was five stars.
Superhost
A clear view of a tranquil swimming pool is framed by wooden beams, showcasing reflections of surrounding greenery. Lush tropical plants create a serene backdrop, enhancing the connection to nature.
Home in Gamboa
4.87 out of 5 average rating, 95 reviews

BirdHouse@ Gamboa Panamá Canal

FrancescaRating, 5 stars2 months ago
What an incredible stay we just had. This is our third time to Panama and our first in Gamboa and it was amazing. The home was gorgeous and spacious. The kid zone was a blast for both kids and adults. We went on a zip lining tour and the boat tour of the canal, monkey island and Embera tribe and they were worth every penny. Our 9-12 year olds felt safe and saw every animal on our wish list. Just an amazing adventure topped off by the privacy of our own home with a gorgeous pool. We just loved it. Thank you so much!!!
Top guest favorite
A calm swimming pool reflects the surrounding buildings, with lush palm trees providing greenery. A spacious gazebo is positioned at the pool's edge, accompanied by several shaded lounge chairs for relaxation.
Apartment in Buenaventura
4.99 out of 5 average rating, 102 reviews

Exclusive apartment steps from the sea in Puntarena

MarlaRating, 5 stars1 week ago
Great place to relax with family and friends. Pool and supermarket is within walking distance. Friendly and helpful staff of Buenaventura they will drive around the area.
Guest favorite
A wooden deck surrounds a tranquil pool, complemented by a large umbrella providing shade. Two lounge chairs are positioned nearby, while a round dining table with multiple chairs is visible, set in an inviting outdoor space surrounded by lush greenery.
Home in Playa Bluff
4.89 out of 5 average rating, 44 reviews

Jungle House 100m from the beach

RiaRating, 5 stars1 month ago
The Jungle House at Playa Bluff was a great getaway destination for our 2 families, with 4 adults and 6 children, ages 4-11. The pool was great and the sleeping arrangements worked well for us. There is a decent kitchen, but we mostly ate at nearby restaurants or on our daily adventures. The house is about a 25 min taxi ride from the main town and the road can get soupy, but any of the truck taxis can easily get to the house. The beach is stunning, although not great for swimming with rip tides and currents. The host was super responsive to all questions and I would highly recommend this house. We even saw sloths and monkeys right around the house.
Guest favorite
A scenic view of a beachfront complex features landscaped gardens, multiple swimming pools, and palm trees. The ocean extends to the horizon under a colorful sky. Paths lead towards shaded areas, and guests are visible walking along the manicured pathways.
Condo in San Carlos
4.95 out of 5 average rating, 38 reviews

Lovely Beachfront Condo at Ensenada Beach

OmarRating, 5 stars2 months ago
We had a great time during our short stay, quiet beautiful condo with big windows and a great view of the ocean, it was close to markets and fast food restaurants, great location overall, we are sure to return.
Guest favorite
A modern outdoor pool reflects the surrounding structures, with large glass windows visible in the background. Palm trees line the edges of the pool area, providing a touch of greenery. Lounge chairs are positioned nearby, enhancing the inviting space for relaxation.
Home in Playa Malibú
4.91 out of 5 average rating, 11 reviews

MoMa Malibu, Beach front

EstebanRating, 5 stars1 month ago
Our stay at this beach house was absolutely wonderful. From the moment we arrived, we felt right at home thanks to the warmth and attention to detail that can be seen in every corner. The location is unbeatable, with the relaxing sound of the waves as a constant soundtrack and the beach just a few steps away. We really enjoyed the sunsets from the pool. The house was spotless, very nicely appointed and tastefully decorated. Definitely an unforgettable vacation. Thank you so much for sharing this paradise with us!"

Mansion rentals with a pool

Guest favorite
Vacation home in San Carlos
4.92 out of 5 average rating, 48 reviews

Welcome to our house in Playa Corona

FranklinRating, 5 stars1 month ago
It's the perfect place to disconnect from everything and at the same time from everything just minutes away. The house is exactly as described and has an amazing view. There are fruit trees, palm trees and beautiful veraneras that make the place a paradise. I went with my wife and 5 adult children, and they were all comfortable. The terrace is huge and the pool is large. Fully recommended
Guest favorite
Villa in Rio Hato
4.97 out of 5 average rating, 30 reviews

Villa Agueda Decameron, golf club and swimming pool

JeremyRating, 5 stars5 months ago
What a place, one of the better Air B &B’s in Panama, have everything you require, nice pool, cold jacuzzi that works, very amazing stay Annelise, thanks for everything.
Superhost
A scenic view of a spacious outdoor area featuring a refreshing pool surrounded by palm trees. The house is visible with large windows, and seating areas are arranged on the lawn, inviting relaxation in a tropical environment.
Place to stay in Portobelo
4.86 out of 5 average rating, 22 reviews

Oceanfront Villa

AdrianaRating, 5 stars3 months ago
This place is perfect to enjoy a relaxing het away, having the beautiful ocean view and tropical breeze right outside of the house it is priceless! The pool and Jacuzzi are well maiy and make a great complement of the whole experience! The host thought about every detail to make the guests very welcome, by providing essentials for personal cleaning products, kitchen extra essentials and outdoors supplies. We really enjoyed the stay.!
Top guest favorite
A bright living area features large glass doors that provide a panoramic view of the beach and ocean. A spacious sectional sofa is positioned near natural light, complemented by a wooden dining table. Elegant decor elements include woven light fixtures and fresh greenery.
Condo in Maria Chiquita
4.98 out of 5 average rating, 55 reviews

Playa Escondida Lux Beachfront Haven:Oceanview Apt

FelipeRating, 5 stars1 month ago
Wonderful place. Very spacious and well decorated. Wonderful view, my guests from outside of panama commented on how they thought the apartment was “wonderful”. Samy a super host, very fast and easy to communicate with.
Guest favorite
A tranquil pool area is framed by lush palm trees, with a clear view of the beach in the background. The inviting water of the pool reflects the bright blue sky, creating a serene atmosphere for relaxation. A white lounge chair is positioned nearby.
Chalet in Las Lajas
4.79 out of 5 average rating, 66 reviews

Front beach exclusive Villa.

ArianaRating, 5 stars2 months ago
Just returned from an incredible stay at Rafael’s beautiful beachfront home in Las Lajas, where we gathered to celebrate my mom’s 70th birthday. The house was perfect for our family—spacious, welcoming, and thoughtfully designed. Four of the five bedrooms had their own private bathrooms, making it easy for everyone to have their own space. The master bath was a dream with its Jacuzzi tub and separate shower, another had a soaking tub and rain shower, and the others featured spa-like rain showers. We enjoyed slow mornings with ocean views, meals in the fully equipped kitchen, and evenings by the pool. Rafael was a wonderful host—responsive and kind. This home helped us create memories we’ll never forget.
Guest favorite
A serene outdoor area is showcased, featuring a swimming pool surrounded by well-maintained grass and a decorative fountain in the foreground. Lounge chairs are positioned near the pool, while lush greenery offers a sense of privacy.
Home in Panama City
4.95 out of 5 average rating, 40 reviews

Nice duplex house with a swimming pool.

MaricelRating, 5 starstoday
Don Gerardo was an amazing host. He picked my family and I up from the airport and welcomed us to his place with a cake which he did not need to do at all. He went above and beyond by offering us advice on local spots and attractions and completely changing the washing machine when the last one had issues. He was very attentive and welcoming to my elderly parents. He even drove my daughter back home from the airport after dropping her off there (one hour round trip) as she had forgotten something important at his place. The house was huge and exactly what my family and I needed. There were no issues at all from the house apart from the aforementioned washing machine which he rectified immediately when we were out of the house. Would definitely recommend to anyone with a big family to stay in Gerardo’s place. He is just an amazing guy and super super host . Highly recommended
Superhost
A large outdoor space features a kidney-shaped swimming pool with a connected hot tub, surrounded by lush greenery and palm trees. The pool area is bordered by vibrant stone pathways and a small building with a clay tile roof in the background.
Home in PA
4.8 out of 5 average rating, 95 reviews

Villa GiGi - Beach Home Panama Santa Clara

EmilyRating, 5 stars3 months ago
Lovely home very close to the beach. There was so much to do at the house we didn't spend much time at the beach! The pool was great, we thoroughly enjoyed our time here.
Guest favorite
A well-lit bedroom features a spacious bed with white linens and colorful accent pillows. Two nightstands with green lamps are positioned beside the bed. Natural light enters through a window with sheer curtains, and a ceiling fan is mounted above, enhancing ventilation.
Condo in El Chirú
4.96 out of 5 average rating, 28 reviews

Buenaventura | Luxury Beach Apartment | Panama

RenataRating, 5 stars1 month ago
Our stay in Rapha's apt was spectacular. The apartment is super comfortable to be with a family, it is very well equipped and very clean. They also have details that make you feel at home, like a baby chair, plates, glasses, etc. We loved the place, the apartment and the attention we received from Rapha! We will definitely come back and recommend it 100%.

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