Boutique hotels in Panama

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Panama

Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

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Superhost

A furnished bedroom features a spacious bed with white linens, flanked by bedside tables with lamps. Soft artwork adorns the wall above, while a bench rests at the foot of the bed. A cozy throw drapes over the bench, completing the inviting arrangement.

Hotel room in Boquete

Villa Alejandro - Tastefully Furnished Room

Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

4.89 out of 5 average rating, 117 reviews

Guest favorite

An outdoor pool is illuminated in a calming blue hue, surrounded by lounge chairs. Umbrellas provide shade, while plants add a touch of greenery. The night sky and distant hills create a serene backdrop, enhancing the tranquil atmosphere of the space.

Hotel room in Taboga Island

Taboga Palace Hotel. Beach front English Bouquet

Shush,, Its a Secret Paradise, a beach front location, and surrounded with different restaurants and fondas, Friendly staff, English and Spanish spoken . , Why not spoil yourself once in your life, come stay in our Palace , you come to us and you wont want to leave. The Island is safe, the people friendly and welcoming. Hiking, Kayaking, Snorkeling, fishing, Swimming, Come explore the Island of Flowers, Or just chill out. Specialty of the house are Daves , Strong Margaritas .

5.0 out of 5 average rating, 13 reviews

Superhost

A spacious bed is positioned centrally in the room, adorned with neutral-toned bedding. Two ottoman-like stools are placed at the foot of the bed. A laptop is being used on the bed, with soft lighting emanating from lamps on either side, creating a cozy ambiance.

Hotel room in San Carlos District

Surf, Beach & Relax Boutique Stay I Manglar Lodge

Manglar Lodge is a relaxed boutique beach stay in the surf town of El Palmar, San Carlos, on Panama’s Pacific coast. Surrounded by tropical gardens, it’s the perfect place to unwind and enjoy the laid-back beach vibe. This king room includes Wi-Fi, A/C, cable TV, private bathroom, mini fridge, microwave, coffee maker, and a cozy atmosphere for a comfortable stay. Just a short walk to the beach, surf spots, restaurants, and local cafés. **Upper floor room, stairs required. **No pets allowed.

4.78 out of 5 average rating, 141 reviews

Top guest favorite

The bungalow features a screened-in porch, framed by lush greenery and colorful plants. Warm sunlight casts shadows across the wooden structure, creating a serene and inviting atmosphere amidst the surrounding foliage.

Hotel room in Bastimentos

Casa Florecer- bungalow at the edge of the sea

Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A stand alone studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. We have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

4.96 out of 5 average rating, 71 reviews

Superhost

A spacious living area is furnished with woven seating and a glass coffee table. Large windows offer views of the sea, while a desk and flat-screen TV are visible. A kitchenette with modern appliances complements the inviting space, enhanced by natural light.

Hotel room in Isla Colón

Hotel Palma Royale - 1 bedroom suite w/ kitchen

Luxury suite with separate bedroom with queen size bed, kitchen, and living area, balcony with spectacular sea views, bathroom with rain water shower, office desk, air conditioning, coffee pot with grinder and panamanian coffee beans, flat screen tv with cable, upper floors, free wifi, large quality windows and doors, pillow top mattresses, marble or coral tile, bamboo flooring, non-smoking rooms, beach towels, umbrellas, blow dryers, laundry service, board games.

4.86 out of 5 average rating, 28 reviews

Guest favorite

A rustic wooden bungalow stands elevated among lush tropical foliage, featuring a private plunge pool surrounded by sun loungers. Large windows with turquoise drapes provide a view of the evening sky, while steps lead to the entrance of the cozy retreat.

Hotel room in Bastimentos

The Firefly oceanfront casita w/ pool Adults only

Our b&b is a little off the beaten path but we love it that way. Listing is for one of our two private, oceanfront bungalows. We can let you know which one is available at time of booking. We are an eco lodge & describe our vibe as "hip, rustic beach house". Our rooms are fan cooled & have in room safes. Pool is shared by all five rooms. Breakfast is included. If a "resort" or 4 star place is your vibe, we are probably not for you :) We accept guests 15 and up.

4.95 out of 5 average rating, 56 reviews

Guest favorite

The room features two spacious beds with modern wooden frames. A wooden bench runs along the foot of one bed. A large area rug adds a pop of color to the floor. Soft lighting complements the earthy tones of the walls.

Hotel room in Playa Venao

Brisa - Ocean Views, Calm Vibes, King/Twin beds

Brisa is the perfect family room on the ground floor, made for relaxing after a fun day in the sun. Equipped with a mini fridge, AC, TV (ready for you to sign into all your online viewing accounts), hot/cold water and beautiful breezy covered seating area outside with ocean views. Steps from our pool! *Additional guest, available to kids up to 12 year old* *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host. *

5.0 out of 5 average rating, 18 reviews

Guest favorite

A charming stone structure is surrounded by lush greenery in this tranquil setting. Soft lighting enhances the architectural details, while the inviting garden area features neatly trimmed hedges and flower beds. A patio area can be seen beside the main building, perfect for outdoor relaxation.

Hotel room in El Valle de Antón

Medieval Suite Nature & Art

La Corte del Re is a tourist structure composed of a set of suites with a medieval theme (macabre art) immersed in the woods where art and nature merge in the heart of Anton's Valley. A few steps from the center are equipped with all comforts and have a park, pool, lake with Koi carpe and parking. They don't have a kitchen. Guests can enjoy a Muay Thai, jiu-jitsu and MMA academy.

4.84 out of 5 average rating, 51 reviews

Top guest favorite

Large green doors open to a charming balcony, revealing a view of a red-tiled roof and a small table with two chairs. A soft sofa is positioned nearby, complementing the inviting atmosphere of the space.

Hotel room in San Felipe

Corcho rooms #2 - king room with balconies

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

4.86 out of 5 average rating, 161 reviews

Guest favorite

A room featuring a wooden bunk bed and a spacious bed against a wall, with light blue walls enhancing the interior. A bathroom entrance is visible, and a small window allows natural light to enter. Soft furnishings include a blanket and towels placed on the beds.

Hotel room in Bocas del Toro Province

Surfari Bocas Quadruple Room #24

Surfari Bocas is close to restaurants and dining, nightlife, family-friendly activities, the airport, water-taxis, and great views. You’ll love Surfari because of its proximity to everything, the ambiance, . My place is good for couples, solo adventurers, business travelers, and families. The rates are room only.

4.72 out of 5 average rating, 69 reviews

Guest favorite

A bright blue room features a queen bed with a patterned bedspread and two pillows. A small wooden table and chair are visible, while colorful fish art adorns the walls. A door leads to the bathroom, and a window allows natural light into the space.

Hotel room in Las Tablas Abajo

Blue Room for 2 at Casa Lassini - Oceanfront!

Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.

4.81 out of 5 average rating, 91 reviews

Guest favorite

The exterior features a warm yellow facade with a large arched window and distinct wooden door, complemented by a neatly landscaped flower bed. Paved pathways lead to the entrance, providing a welcoming approach to the boutique hostel.

Hotel room in Bethania

Entire place Sofia's B&B Hostal Boutique

Boutique hostel accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. You can make use of the well-equipped kitchen, comfortable living room and dining room. We have a washer and dryer at your disposal for an additional cost.

4.89 out of 5 average rating, 27 reviews