
Hotel vacation rentals in Panama
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Top-rated hotel rentals in Panama
Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

Villa Alejandro - Tastefully Furnished Room
Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

Treetop views of the Pacific in a boutique cabaña
No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Wanakaset forest villa, pool & river, 7 rms 16 pax
Casa Rancho accommodates up to 16 people. This exceptional property, in the heart of a protected and luxuriant nature, is ideal for family or friends reunions, seminars, retreats, team buildings, bird watching, etc. The luxurious property is surrounded by El Rio Papayal to swim in its clear and refreshing water. Additionally, there is a large shared pool for guests to enjoy. The house has been recently renovated, is comfortably equipped and tastefully decorated.

The Firefly B&B oceanfront bungalow w/ pool
Our b&b is a little off the beaten path but we love it that way. Listing is for one of our two private, oceanfront bungalows. We can let you know which one is available at time of booking. We are an eco lodge & describe our vibe as "hip, rustic beach house". Our rooms are fan cooled & have in room safes. Pool is shared by all five rooms. Breakfast is included. If a "resort" or 4 star place is your vibe, we are probably not for you :) We accept guests 15 and up.

Boutique Inn_The Hill 2_Private Entry_Tripple_+16
The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 2 was designed as a boutique hotel room with separated private entry and communal kitchen.

Iwanna Green Ecolodge Room with Private Bathroom
Discover your eco-friendly oasis in the heart of a beautiful natural setting. Our room with a private bathroom offers: Full bed plus full sofa bed Spacious, private bathroom with eco-friendly amenities Windows overlooking the garden, ideal for relaxing Free high-speed Wi-Fi Healthy breakfast included (toast, eggs, seasonal fruits/coffee and more) Common areas: terraces, pool, rest areas and more

Desk & Dream Room in flat for work and rest
Disfruta de la comodidad de este alojamiento tranquilo y céntrico en el corazón de San Francisco, tiene escritorio dentro de la habitación para trabajar o estudiar en un ambiente relax, con las demás comodidades incluyendo televisor led HD de 32" Justo en la calle de al lado está el super mercado, farmacia al frente, restaurantes, tiendas de chinitos, panaderías, paradas del metro bus cercanas.

La Chunga
La Chunga is in a difficult access indigenous community without electricity or roads. Come see this gem of a community and the indigenous way of life. You’ll love this place because of the nature walks, the wildlife, the gastronomy, and the people. We have a number of guided tours and adventures. My place is good for adventurers trying to see something new and exciting.

Primavera Suit in Boquete
Enjoy the simplicity of this quiet and central accommodation in town, just a few steps from grocery stores, restaurants, bars, coffee shops, with easy access to public or private transportation. This room has a comfortable bed, private bathroom with hot water ample space, the kitchen is perfectly equipped to share with two other rooms, the garden is beautiful.

Corcho rooms #2 - king room with balconies
Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

Casa Manila Doble Room with terrace
Welcome to our calm place in front of the ocean. The place is perfect for relaxing on your private terrace and offers breathtaking views of the pacific ocean. In our freshly renovated rooms with A/C you can enjoy a cold breeze after a sunny day. At the end of the day you will be surprised by the best sunset in Santa Catalina.

Ocean Front House on exclusive Contadora Island
Whale season has begun! July-October 🐳 Welcome to your paradise on Contadora Island, a hidden gem in the heart of Panama's Pearl Islands. This stunning Ocean Front house offers unparalleled views of the turquoise waters providing the perfect escape for those seeking both tranquility and adventure.
Popular amenities for Panama hotel rentals
Family-friendly hotel rentals

Estrella Room - Quiet, budget friendly - queen bed

Private, open concept room with pool/beach access!

Casa Hernández 11

100m2 apartment in Megapolis Panama hotel

B) Beach, surf and Relax with King size bed

Villa Sharon Room 02

Comfortable Sea View Jungalow - breakfast incl

Pool side, Family suite, two bedroom one bath.
Hotel rentals with a pool

Colibrí Suite: Relaxation and Comfort

B&B Cabanas los colibris

Boutique Skate + Surf Hotel | King Bed & Views R1

Beach Apartament Villa Deluxe

Double room IXORA with partial ocean view balcony

Decameron Villas Private Room #3

Deluxe King Ocean View @ Villa Marina Playa Venao

Playa Blanca Town Centre Resort Luxury Beach NEW!
Hotel rentals with a patio

Boquete Firefly Inn Downstairs

Cozy private room with bathroom in Alto Boquete

Villa in Playa Blanca Resort Rio Hato

Conch – Oceanfront Ground-Floor Studios – Panama

Lovely Oceanfront Room in Adventure Lodge

Ivonne's House

Coronado, beach house, enjoy as a family

La Husseyenda - Birdwatcher Haven
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