
Villa vacation rentals in Panama
Find and book unique villas on Airbnb
Top-rated villa rentals in Panama
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama villa rentals
Private villa rentals

Enjoy a spectacular villa in Playa Escondida

Bocas Overwater Luxury Villa & Lodge

Beachfront Property is Your Own Piece of Paradise

Casa Almendra

Villa Oceana - Blue Venao 3BR

Pacific Escape

Bahia Breeze 3 bdrm nature sanctuary with pool

Villa Futura by AcoModo
Luxury villa rentals

Beach House Where Emy

Beautiful Villa in Playa Escondida

La Casa de las Uvas, an oasis with ocean views

Casa Caracola. Luxury villa. 200 mts from beach

Breathtaking Views Mansion w/King Beds

@Villa SharonBeach House in Playa Blanca, Farallon

Incredible Hacienda with ocean and river View

*New Tropical Lodge Oasis|Private Pool & Breakfast
Villa rentals with a pool

Villa 3 bedrooms, Pet-friendly (V4-PBA)

Charming & Quiet villa

Super Private Beachfront 3BR Villa & Infinity Pool

25% OFF The Family Mini Resort House @Punta Barco

Villa Ceviche, Home at the Heart of Venao

Villa with a swimming pool, soccer field, and stream

Villa La Vista-Panama's majestic mountain hideaway

Caribbean Beach House with Pool
Destinations to explore
- Smoking-friendly rentals Panama
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- Rentals with a sauna Panama
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- Bed and breakfasts Panama
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- Tiny house rentals Panama
- Rentals with a hot tub Panama
- Pet-friendly rentals Panama
- Rentals with an accessible height bed Panama
- Cottage rentals Panama
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- Rentals with outdoor seating Panama
- Townhouse rentals Panama
- House rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Farmstay rentals Panama
- Beach house rentals Panama
- Waterfront rentals Panama
- Rentals with beach access Panama
- Rentals with a fire pit Panama
- Apartment rentals Panama
- Rentals with pools Panama
- Rentals with lake access Panama
- Rentals with breakfast Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Treehouse rentals Panama
- Nature eco lodge rentals Panama
- Bungalow rentals Panama
- Island rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Rentals with a fireplace Panama
- Rentals with a patio Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
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