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Panama vacation rentals

Book unique homes, vacation rentals, and more on Airbnb

Top-rated vacation rentals in Panama

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Guest favorite

Cottage in Bocas del Toro Province

4.96 out of 5 average rating, 166 reviews

Rustic cottage-Ocean views/walk to surfing/Jungle

Casa Palmera is located near the only beach to the north/west side of Isla Carenero, with a beautiful ocean view where the sun sets in a secluded and peaceful area. Only a 5 minute walk to the Carenero Surf Break . Restaurants are within walking distance, hike around the island, or use the kayaks and see the beauty. We are 5 minute boat taxi away from the main town of Bocas, but everything you need to make your vacation unforgettable is on this island! Drinking water included.A/C in bedrooms

Mar 1 – 8

G$32,303 GYD per night
Guest favorite

Home in Bocas del Toro District

4.93 out of 5 average rating, 191 reviews

Orange House - Over The Water Rentals

Enjoy golden sunsets across the bay from the Orange House at Over The Water Rentals. Home away from home in a tropical paradise. Relax on your outdoor lounge or explore the bay. The house has snorkel gear, SUP's & kayaks for guests to use for free. Bikes can be rented. Located close to town & airport in a quiet local neighborhood. The house features a king size master bedroom & queen guest room, spacious hot water shower, handmade organic toiletries, fully equipped kitchen & high speed wifi

Nov 19 – 26

G$29,645 GYD per night
Guest favorite

Guesthouse in Torio

4.91 out of 5 average rating, 106 reviews

Torio guesthouse with panoramic view

Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.

Feb 27 – Mar 6

G$16,188 GYD per night

Popular amenities for Panama vacation rentals

Panama house rentals

Superhost

Home in Altos del Maria

4.78 out of 5 average rating, 232 reviews

Modern House in Altos del Maria, Panama

Apr 17 – 24

G$54,875 GYD per night
Guest favorite

Home in Pedasí

4.94 out of 5 average rating, 109 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Oct 20 – 27

G$35,956 GYD per night
Superhost

Home in Bocas del Toro District

4.82 out of 5 average rating, 103 reviews

Amazing over the water house

Dec 31 – Jan 7

G$45,413 GYD per night
Guest favorite

Home in El Valle de Antón

4.93 out of 5 average rating, 113 reviews

Rustic family mountain home - 5 min walk to town!

Jun 18 – 25

G$23,781 GYD per night
Guest favorite

Home in Las Colinas de Caceres de Arraijan

4.98 out of 5 average rating, 195 reviews

Tropical Haven with Yoga Platform

Sep 9 – 16

G$65,729 GYD per night
Superhost

Home in El Valle de Antón

4.81 out of 5 average rating, 118 reviews

Casa Antares

Dec 16 – 23

G$8,772 GYD per night
Guest favorite

Home in Panamá

4.93 out of 5 average rating, 287 reviews

Estudio Privado a 10 Min del Aeropuerto !

May 13 – 20

G$8,626 GYD per night
Superhost

Home in Bajo Boquete

4.81 out of 5 average rating, 106 reviews

Secluded Riverfront Home - Boquete area with Pool

Jan 29 – Feb 5

G$16,546 GYD per night
Guest favorite

Home in Los Algarrobos

4.99 out of 5 average rating, 117 reviews

New house! 5 min from David on the Boquete highway

Sep 10 – 17

G$15,164 GYD per night
Guest favorite

Home in Paso Ancho

4.88 out of 5 average rating, 126 reviews

Vista El Baru - Volcan, Paso Ancho, Panama

Feb 24 – Mar 3

G$15,770 GYD per night
Guest favorite

Home in Las Lajas

4.9 out of 5 average rating, 178 reviews

Casa Inteligente Coronado Piscina/Jacuzzi Privados

May 3 – 10

G$27,673 GYD per night
Guest favorite

Home in Bocas del Toro

5.0 out of 5 average rating, 5 reviews

La Casita Barrbra BnB

Jun 11 – 18

G$32,255 GYD per night

Panama condominium rentals

Guest favorite

Condo in Panama

4.99 out of 5 average rating, 200 reviews

Patty’s Cozy & Quiet Studio with K-bed in Casco

Oct 9 – 16

G$20,605 GYD per night
Guest favorite

Condo in Chame

4.96 out of 5 average rating, 135 reviews

Exclusive Beachfront apartment 1Hour from Pma City

May 16 – 23

G$31,638 GYD per night
Guest favorite

Condo in San Carlos District

4.95 out of 5 average rating, 134 reviews

Punta Caelo beachfront apartment San Carlos

Oct 22 – 29

G$33,575 GYD per night
Guest favorite

Condo in Panamá

4.92 out of 5 average rating, 132 reviews

Spacious Executive Apartment

Sep 18 – 25

G$20,556 GYD per night
Guest favorite

Condo in Panamá

4.82 out of 5 average rating, 119 reviews

Cozy two bedroom apartment

Oct 21 – 28

G$18,385 GYD per night
Guest favorite

Condo in Panama City

4.89 out of 5 average rating, 195 reviews

Park View Luxury Apartment

Nov 9 – 16

G$31,241 GYD per night
Superhost

Condo in Maria Chiquita

4.85 out of 5 average rating, 425 reviews

Relaxation by the sea

Oct 17 – 24

G$15,617 GYD per night
Guest favorite

Condo in Panamá

4.97 out of 5 average rating, 145 reviews

Excellent complete apartment, Panamá, Panamá

Oct 2 – 9

G$45,874 GYD per night
Guest favorite

Condo in Panamá

4.95 out of 5 average rating, 154 reviews

Los Diamantes Maximo. Prepare to be stunned.

Sep 14 – 21

G$52,653 GYD per night
Guest favorite

Condo in Nueva Gorgona

4.94 out of 5 average rating, 146 reviews

Hermoso Apto de Playa-PH Royal Palm-Gorgona

Aug 20 – 27

G$19,354 GYD per night
Guest favorite

Condo in Panama

4.94 out of 5 average rating, 173 reviews

Apartamento de Playa con piscina y toboganes!

Jan 10 – 17

G$17,504 GYD per night
Superhost

Condo in Maria Chiquita

4.91 out of 5 average rating, 123 reviews

Playa Escondida , Paraíso en Colón/private beach

Oct 14 – 21

G$92,032 GYD per night

Other great vacation rentals in Panama

Guest favorite

Townhouse in Panama

4.94 out of 5 average rating, 126 reviews

Unique Historic House in Casco

Aug 26 – Sep 2

G$134,869 GYD per night
Guest favorite

Apartment in Jaramillo

4.99 out of 5 average rating, 253 reviews

Stunning views Boquete private mountain estate

Jan 1 – 8

G$14,844 GYD per night
Superhost

Farm stay in Santa Fe

4.91 out of 5 average rating, 245 reviews

Santa Fe villa with a espectacular view

Jun 2 – 9

G$16,731 GYD per night
Superhost

Bungalow in Bocas del Toro

4.89 out of 5 average rating, 126 reviews

Romantic Over the Water Bungalow with Floating Bed

Oct 13 – 20

G$35,958 GYD per night
Superhost

Cabin in Panamá Oeste

4.8 out of 5 average rating, 211 reviews

Cabaña Mirador by Casa Amaya

May 25 – Jun 1

G$13,012 GYD per night
Guest favorite

Earthen home in playa el arenal pedasi

4.96 out of 5 average rating, 114 reviews

Earth House Pedasi Experience

Jul 11 – 18

G$12,834 GYD per night
Guest favorite

Bungalow in Provincia de Chiriquí

4.98 out of 5 average rating, 121 reviews

Romantic getaway

Oct 24 – 31

G$10,001 GYD per night
Guest favorite

Cabin in Torio

4.98 out of 5 average rating, 92 reviews

Cozy open space, unique jungle views, river access

Nov 26 – Dec 3

G$24,450 GYD per night
Guest favorite

Apartment in Panamá

5.0 out of 5 average rating, 53 reviews

Cozy n Comfy con balcón in the heart of Casco

Sep 9 – 16

G$23,654 GYD per night
Superhost

Villa in Bocas del Toro

4.86 out of 5 average rating, 29 reviews

Bocas del toro - Villa over the water- Bahia Coral

Aug 27 – Sep 3

G$78,841 GYD per night
Guest favorite

Villa in Río Hato

5.0 out of 5 average rating, 38 reviews

Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

Apr 20 – 27

G$95,175 GYD per night
Guest favorite

Cabin in Panamá

4.97 out of 5 average rating, 37 reviews

The Crystal House: Luxury Modern Wood Cabin

Oct 2 – 9

G$88,555 GYD per night

Your guide to Panama

All About Panama

A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.

The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.


The best time to stay in a vacation rental in Panama

The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.

Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.


Top things to do in Panama

Casco Viejo

As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.

Panama Canal

When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.

Bocas Del Toro

Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.

Destinations to explore

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