
Apartment vacation rentals in Panama City
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Top-rated apartment rentals in Panama City
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Impresionante con vista al mar y a Panamá city
Vive una experiencia única, apartamento moderno y con estilo propio, donde cada amanecer y atardecer se convierte en un espectáculo. Disfruta de impresionantes vistas a la ciudad de Panamá, la bahía y el Casco Antiguo desde la comodidad de tu alojamiento. Ubicación Inmejorable Situado a solo 5 minutos del encantador Casco Viejo y del famoso mercado de mariscos, y a 10 minutos de zona bancaria. Además, contarás con una estación de metro y varias paradas de autobús a solo unos pasos del edificio

The Penthouse Annex
Inspired by Panama's rich history with France and located in one of the oldest watch towers in Panama, this chic apartment combines original features of this historically important building with the elegance and style of Europe. Perfectly situated to indulge in the restaurants, cafes, museums and boutique stores of Casco Viejo, and equipped with everything you expect from a home-from-home base, the annex is the perfect combination of comfort and style for couples and small groups of friends.

Apartamento moderno en el corazón de Obarrio
Este apartamento destaca por su ubicación privilegiada en Obarrio, con diseño moderno y acogedor. Situado en el piso 14,ofrece una vista espectacular, su decoración en tonos neutros transmite serenidad. La comodidad de tener dos baños lo hacen único. Ideal para viajeros que buscan tranquilidad y funcionalidad. Ubicado a pocos pasos de la calle 50 y del icónico edificio el Tornillo. Estas rodeado de casinos, hoteles y restaurantes. Zona segura para caminar y disfrutar de la ciudad.

Tropicool Loft w/rooftop steps from Casco
This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

2BR King Suite Ocean View, Casco, Canal 500MB WIFI
Experience Yoo Panama by world renown architect Philippe Starck. Massive unit 155 m2 / 1,700 ft2 ocean view apartment with an unobstructed view of Panama City/Pacific Ocean overlooking the Panama Canal, Casco Viejo & Cinta Costera. Views & location don’t get better than this. Each bedroom is a King Bed suite. The apartment is located on the prestigious Avenida Balboa. There is a grocery store and 3 of PA's most renown restaurants in the building. Blazing fast wifi at 500mgbs.

Unique Luxury 3-story Loft at the Yoo
Experience the luxury of a world renowned Philippe Starck designed building. Our 3-bedroom sanctuary is a unique 3-story loft that boasts breathtaking city views, an open-plan kitchen, sleek marble floors, and premium amenities. Steps away from Panama City’s premier attractions, shopping, and dining. Dive into top-tier amenities: a pristine pool, state-of-the-art gym, relaxing spa, and three of the best restaurants in the city! Embrace Panama in unmatched style.

Escápate al Corazón de Casco con Balcón Privado
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Amazing loft with an iconic view of Casco Viejo
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Jeronimo,” this restored- colonial building was built in the year 1850, and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Apartamento de lujo Panamá centro, área bancaria
Contamos con una ubicación estratégica justo sobre la vía principal de Panamá (Calle 50) Bella Vista, te encontraras ubicado en el corazón del área bancaria. Si vienes por trabajo o vacaciones, este es el lugar ideal, encontrarás todo tipo de restaurantes a los alrededores, comercios, centro comerciales, tendrás la Cinta Costera a tan solo 10 minutos a pie donde podrás pasear o ejercitarte. Diversión y disfrute a pocos pasos

Apartamento completo en Panama
Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Jacuzzi in colonial ruins in beautiful apartment
Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Best location & Rooftop Pool Apto with elevator

Luxury 2BR w/Ocean Views – 27th Fl, Wanders YOO

Suite Luxury 30th View , Cinta Costera Panama

PH Yoo 44i – Apartamento con Vista al Mar

Sea View Balcony • Remote Working • San Francisco

Ocean View private Studio Apartment

Departamento con vista al mar estilo Resort

The Captain's Canal View Penthouse
Private apartment rentals

Beautiful apartment in Casco Viejo ST. George D

Vista al mar con diseño industrial

Apto 2BR Panamá Costa del Este

Apartamento Av. Balboa, Yoo&Arts

Luxurious Apartment Oceanfront View

Panama Dream View Escape

YOO Panama · Luxury signature ocean view. 57th fl

Exclusivo Apto/Av Balboa/Pool/Gym/AC/View/Parking
Apartment rentals with a hot tub

3 bedroom penthouse with spectacular views!

Apartamento entre oceano y selva

Luxury Apartment in Panama | 2BR + Views + Pool

Luxury Beachfront Apartment Near Panama City

New Flat with Ocean + City Views

Amplio Apartamento Frente al Mar

Tropical Paradise at Playa Bonita

Coastal Chic Executive Studio in Panama City
Quick stats about apartment rentals in Panama City

Total vacation rentals
Explore 2,770 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

Verified guest reviews
Over 71,040 verified reviews to help you choose

Family-friendly vacation rentals
850 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 990 rentals that welcome pets

Vacation rentals with a pool
1,730 properties feature pools

Rentals with dedicated workspaces
1,720 properties have a dedicated workspace

Wi-Fi availability
2,640 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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- Things to do Panama
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