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Apartment vacation rentals in Panama City

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Top-rated apartment rentals in Panama City

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Top guest favorite

A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.

Apartment in Panama City

5 out of 5 average rating, 33 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Apartment in Panamá

5 out of 5 average rating, 3 reviews

Incredible Renovated Apartment in Casco Viejo

Disfruta de un loft único en el corazón de Casco Viejo, ubicado en la emblemática Calle 4ta. Este apartamento ha sido totalmente remodelado, combinando a la perfección el encanto histórico de sus muros originales con un diseño moderno y elegante. La doble altura, la pared de piedra restaurada y los detalles artesanales en los pisos crean un ambiente acogedor y sofisticado. Su distribución abierta con sala, comedor y cocina integrada lo convierten en un espacio ideal para relajarse y compartir.

A welcoming living area features modern furnishings and vibrant artwork. A round wooden coffee table is accompanied by a cozy sofa and armchairs. Natural light pours in from large glass doors leading to a balcony, while a plant adds a touch of greenery.

Apartment in Panamá

4.95 out of 5 average rating, 117 reviews

Apartamento de lujo en Panamá, vista al mar

Ubicado en San Francisco, una de las zonas exclusivas por excelencia en Panamá, donde la gastronomía, historia, modernidad y entretenimiento se combinan mágicamente. Maravillosa ubicación cerca de destinos imperdibles, gimnasio, piscina, coworking, pet spa y terraza. El estacionamiento tiene cobro. Moderno y funcional, este apartamento cuenta con una habitación cama queen, cocina completamente equipada, Wifi, televisión, un balcón espectacular con vista al mar, centro de lavado y sofá cama.

A cozy living area features a comfortable blue sofa against an original brick wall, complemented by a round mirror. A small kitchen area with white cabinetry and modern appliances is visible. A decorative coffee table and elegant chairs complete the inviting space.

Apartment in Panamá

4.81 out of 5 average rating, 148 reviews

The Penthouse Annex

Inspired by Panama's rich history with France and located in one of the oldest watch towers in Panama, this chic apartment combines original features of this historically important building with the elegance and style of Europe. Perfectly situated to indulge in the restaurants, cafes, museums and boutique stores of Casco Viejo, and equipped with everything you expect from a home-from-home base, the annex is the perfect combination of comfort and style for couples and small groups of friends.

An open living space features a large gray sectional sofa paired with a round wooden coffee table. A patterned rug lies beneath, complementing the light wooden flooring. The kitchen area is visible in the background, showcasing modern appliances and a breakfast bar with stools.

Apartment in Panamá

4.94 out of 5 average rating, 151 reviews

Cozy 2 Bedroom w/ Splash Pool

Our place is a 3-story apartment located on the quiet side of Casco Viejo. It has a very private feel to it, which allows for an incredible afternoon of sunbathing or bbqing on our private rooftop. The splash pool allows for a refresh and fits 2 people at a time. This place has so much character from with original exposed stone walls, to the sweeping view of the Arto Chato ruins. It also has a great work space, all the necessities to stay in and cook, watch a movie, etc.

A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.

Apartment in Panamá

4.98 out of 5 average rating, 143 reviews

Escápate al Corazón de Casco con Balcón Privado

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

An inviting pool area features a serene swimming pool surrounded by lounge chairs. The contemporary building's façade is illuminated, showcasing expansive glass windows and greenery, creating a welcoming ambiance for relaxation and leisure.

Apartment in Panamá

5 out of 5 average rating, 12 reviews

Stylish Casco Antiguo Apt • Pool & Parking

Stay in a stylish modern apartment just steps from Panama City’s historic Casco Viejo and the scenic Cinta Costera Recently decorated with a contemporary design, it’s perfect for relaxing or working remotely with fast WiFi. Guests enjoy access to a rooftop with panoramic views and pool, a coworking space, and private parking. Surrounded by top restaurants, bars, shops, and major attractions, it’s the ideal base to discover the magic of Panama.

Top guest favorite

An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.

Apartment in Panamá

4.97 out of 5 average rating, 113 reviews

Apartamento de lujo Panamá centro, área bancaria

Contamos con una ubicación estratégica justo sobre la vía principal de Panamá (Calle 50) Bella Vista, te encontraras ubicado en el corazón del área bancaria. Si vienes por trabajo o vacaciones, este es el lugar ideal, encontrarás todo tipo de restaurantes a los alrededores, comercios, centro comerciales, tendrás la Cinta Costera a tan solo 10 minutos a pie donde podrás pasear o ejercitarte. Diversión y disfrute a pocos pasos

A cozy living area features a light-colored sofa facing a wall-mounted television. A round table is set in front, and woven placemats add texture. Large windows showcase city views and provide natural light, while a bedroom is visible in the background, showcasing a spacious bed.

Apartment in Panamá

5 out of 5 average rating, 108 reviews

Apartamento completo en Panama

Este encantador apartamento está ubicado en uno de los mejores barrios de Panamá, San Francisco, un lugar céntrico donde encontrarás amplía gastronomía, lugares de diversión, cerca a estaciones de buses, y al centro comercial más importante de la ciudad, Multiplaza. Este apartamento céntrico y tranquilo es una oportunidad que no querrás dejar pasar. Ofrece la combinación perfecta de comodidad, belleza y ubicación conveniente.

A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.

Apartment in Panamá

4.93 out of 5 average rating, 92 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

A private terrace features a jacuzzi surrounded by lush greenery against an exposed stone wall. Wooden decking creates a warm ambiance, complemented by two lounge chairs designed for relaxation, offering an inviting outdoor space for guests.

Apartment in Panama City

4.9 out of 5 average rating, 148 reviews

Jacuzzi in colonial ruins in beautiful apartment

Welcome to Casa Marquez Portazgo! This cozy apartment in the heart of Panama City offers comfort and convenience, ideal for your stay. With one bedroom and capacity for two people, you'll enjoy a relaxing atmosphere in 70 m². Located in the San Felipe neighborhood, just steps from the entrance to the Casco Antiguo, it offers a unique experience. You can also unwind in the jacuzzi.

Top guest favorite

A spacious terrace features modern lounge chairs facing an infinity pool that blends with the ocean horizon. Clear blue skies and serene water create a tranquil setting. The surrounding palm trees add a touch of greenery to the area, enhancing the overall views.

Apartment in Panamá

4.99 out of 5 average rating, 103 reviews

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

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Popular amenities for Panama City apartment rentals

Free parking on premises

Air conditioning

Weekly apartment rentals

Top guest favorite

A modern living area features a light-colored sectional sofa paired with two minimalist coffee tables. Large glass windows offer a panoramic view of the city skyline, allowing natural light to fill the space. Neutral tones are complemented by a warm overhead light fixture.

Apartment in Panamá

5 out of 5 average rating, 34 reviews

Acogedor apartamento en Panamá

A modern living area is presented, featuring a comfortable sofa with decorative cushions. A large television is mounted above a sleek media console. Floor-to-ceiling glass doors open to a balcony, showcasing an expansive view of the ocean. Bright natural light illuminates the space.

Apartment in Panamá

5 out of 5 average rating, 6 reviews

Yoo Panama -Lujoso y confortable

A rooftop pool area features a clear, inviting pool accompanied by several lounge chairs. The expansive deck offers stunning views of the city skyline, with tall buildings reflecting the sky's colors. Lush palm trees enhance the serene environment.

Apartment in Marbella

4.94 out of 5 average rating, 62 reviews

Ocean front apartment | King bed + Parking

Top guest favorite

An open living and kitchen area is displayed, featuring a modern design with a light color palette. Two high-backed bar stools are positioned at the kitchen counter, with a stainless steel refrigerator and sleek appliances visible. A comfortable sofa and low coffee table are arranged in the living space.

Apartment in Panamá

4.99 out of 5 average rating, 69 reviews

Céntrico, elegante y minimalista

A spacious rooftop pool area is adorned with lounge chairs and tables, illuminated by soft lights. The pool's vibrant blue water contrasts with the city skyline, featuring tall buildings under a dusky sky, creating a tranquil space for relaxation.

Apartment in Panamá

4.8 out of 5 average rating, 30 reviews

Amplio Apartamento Frente al Mar

An expansive infinity pool is featured, reflecting the clear blue sky above. Surrounding skyscrapers create a modern cityscape, while palm trees add a touch of greenery. The pool area is lined with lounge chairs, inviting relaxation amid the bustling urban environment.

Apartment in Panamá

5 out of 5 average rating, 4 reviews

Ocean view 1 BR • 2 Beds • Megapolis Hotel

The balcony features a round wooden table set with a glass candle holder, surrounded by wicker chairs. A panoramic view of the water and city skyline extends in the background, while colorful market lights add a subtle charm along the railing.

Apartment in Panama City

4.96 out of 5 average rating, 26 reviews

The Captain's Canal View Penthouse

The living area is defined by large, light blue windows that allow ample natural light. A comfortable seating arrangement includes two armchairs and a light-colored sofa, complemented by a coffee table. The warm wooden flooring contrasts with the stone wall, creating a cozy atmosphere.

Apartment in Panama City

4.96 out of 5 average rating, 74 reviews

Amazing loft with an iconic view of Casco Viejo

Private apartment rentals

An illuminated pool reflects intricate designs on its surface, surrounded by modern architecture. Tall buildings rise in the background under a twilight sky, highlighting the vibrant atmosphere of the area. Lounge chairs are arranged nearby, inviting relaxation.

Apartment in Panamá

4.89 out of 5 average rating, 37 reviews

Apartment 2bed,2bath and large terrace in the city

A spacious bedroom features a low platform bed with a textured green duvet, complemented by subtle ambient lighting. Large windows provide an ocean view, while a hanging chair adds a relaxed touch. Green plants enhance the airy atmosphere of the room.

Apartment in Panamá

4.79 out of 5 average rating, 14 reviews

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

A private balcony features a woven chair and a round glass table, set against stunning ocean views. The vibrant blue water stretches to the horizon, with islands faintly visible in the distance, complemented by a sky with soft, fluffy clouds.

Apartment in Panamá

5 out of 5 average rating, 8 reviews

Chic & Modern 1BD Yoo Panama City

Top guest favorite

A cozy sleeping area is presented with a spacious bed dressed in light-colored linens. Two pillows are arranged neatly at the head of the bed, alongside a white rolled towel. An air conditioning unit is mounted above, ensuring a comfortable environment.

Apartment in Panamá

4.96 out of 5 average rating, 57 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

A modern living area is featured with a neutral-toned sofa adorned with accent pillows. Natural light floods the space through large windows, showcasing views of the city. A circular coffee table sits in front of the sofa, complemented by a decorative plant and wall art.

Apartment in Panamá

4.85 out of 5 average rating, 93 reviews

Cozy Apartment with Free Parking Coworking

Top guest favorite

A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.

Apartment in Panamá

5 out of 5 average rating, 49 reviews

Tropicool Loft w/rooftop steps from Casco

A spacious outdoor area features a modern infinity pool, with lounge chairs arranged beside it. A clear view of the city skyline is visible in the distance, while the water reflects the bright sky.

Apartment in Panamá

4.82 out of 5 average rating, 114 reviews

Ocean View private Studio Apartment

Top guest favorite

A cozy bedroom features a gray tufted headboard with decorative pillows, including a blue and white striped pillow. Floor-to-ceiling windows provide natural light and showcase a view of the ocean and marina. Light curtains frame the window, and a nightstand is placed beside the bed.

Apartment in Panama City

5 out of 5 average rating, 6 reviews

Oceanview Paradise in Panama City!

Apartment rentals with a hot tub

A panoramic view captures the skyline of Panama City with numerous high-rise buildings against a backdrop of clear blue skies. Various boats are visible in the foreground on the water, highlighting the bustling maritime activity.

Apartment in Perico island

4.88 out of 5 average rating, 40 reviews

3 bedroom penthouse with spectacular views!

A spacious area is shown with several white outdoor tables and chairs, illuminated by the warm colors of a sunset. Large windows frame the view, allowing glimpses of palm trees and distant coastline, creating a serene environment for relaxation.

Apartment in Panamá

5 out of 5 average rating, 5 reviews

Apartamento entre oceano y selva

A spacious bedroom features a large bed with neutral bedding and contrasting pillows. The stone accent wall is complemented by soft lighting from pendant lamps. A bright yellow chair adds a splash of color, while sheer curtains frame a window, enhancing the overall ambiance.

Apartment in Panamá

4.84 out of 5 average rating, 74 reviews

Hermoso condo colonial con jacuzzi y balcón

A bright living area features a blue sofa adorned with assorted cushions and a decorative throw. A small desk and chair are positioned beside a window, while wall art adds an artistic touch. A coffee table displays a pineapple decoration and a magazine.

Apartment in Panamá

4.79 out of 5 average rating, 87 reviews

New Flat with Ocean + City Views

A spacious outdoor pool area is defined by well-maintained green lawns and tropical palm trees. The pool features multiple sections with a clear blue water surface, surrounded by lounge chairs and shaded cabanas. A backdrop of lush, green hills adds to the tranquil setting.

Apartment in Panama

4.94 out of 5 average rating, 114 reviews

Tropical Paradise at Playa Bonita

A contemporary studio layout is displayed, featuring a spacious bed with a light-colored duvet. Large windows adorned with sheer curtains allow natural light to fill the room. A plush sofa and strategically placed art pieces add to the modern aesthetic.

Apartment in Costa del Este

5 out of 5 average rating, 3 reviews

Coastal Chic Executive Studio in Panama City

A rooftop terrace features a jacuzzi surrounded by a sun deck and lounge chairs. The city skyline is prominently displayed in the background, with a blend of modern buildings and greenery visible. Clear skies and ample sunlight enhance the inviting atmosphere of the space.

Apartment in Panama

4.95 out of 5 average rating, 104 reviews

5A - Boutique Apartment ! High end furnished! 4BR

A combined living and dining area is visible, featuring a wooden table surrounded by four chairs. Two sofas are positioned against the windows, adorned with colorful cushions. Natural light filters through large, partially-blinded windows, with a wall-mounted TV providing entertainment options.

Apartment in Panamá

4.85 out of 5 average rating, 103 reviews

BusinessTripFlat/Comfy/well located/AAs/Queen beds

Quick stats about apartment rentals in Panama City

Total rentals
2.7K properties
Nightly prices starting at
G$2,092 GYD before taxes and fees
Total number of reviews
67K reviews
Family-friendly rentals
870 properties are a good fit for families
Pet-friendly rentals
970 properties allow pets
Rentals with a pool
1.7K properties have a pool

Destinations to explore