
House vacation rentals in Panama City
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Top-rated house rentals in Panama City
Guests agree: these houses are highly rated for location, cleanliness, and more.

Central|Confort|surrounded by nature|Wifi|parking
Conectar con la ciudad y la maravillosa naturaleza al mismo tiempo. Descansar en una hamaca en el balcón lo hace único. Te quedará genial si deseas visitarnos de placer, trabajo (WiFi de alta velocidad); en familia o en grupos de amigos. Casa de la Antigua Zona del Canal, Primer Alto; desde aquí para explorar lugares turísticos y restaurantes. (Cerca Terminal de Buses, Metro Tren, Albrook Mall, parque Metropolitano, Aeropuerto Marcos Gelabert, Casco Antiguo, Coast Way de Amador, Canal de 🇵🇦)

Cantabria House - 10 minutes from the Airport
Spacious and comfortable home just 10 minutes from Tocumen Airport and only 200 meters from the Metro. Perfect for families, groups, or business trips. Fast 500 Mbps Wi-Fi, 3 bedrooms, 2 full bathrooms, fully equipped kitchen, air conditioning throughout the house, cable TV, patio with outdoor furniture, private parking, and self check-in. Long layover, family trip, or work in the city? This home has it all: comfort, location, and privacy. Book now and feel at home from the very first moment!

Mountain Retreat
Relax and unwind at this peaceful property nestled on two hectares of lush tropical vegetation surrounded by the sights & sounds of nature. Located at Panama's Blue Mountain(Cerro Azul), 30 kilometres from Panama City. This cozy & comfortable home is equipped with modern amenities & chic decorative touches. It consists of a main house with 2 bedrooms & a 2 bedroom cottage. It has a spacious terrace, pool & jacuzzi overlooking Panama City. The property also boasts its own spring water well

Apartamento Lilia Airport 1
"Experimenta una estancia cómoda y conveniente en nuestro acogedor apartamento, ubicado a solo 10 minutos del aeropuerto Tocumen. Equipado con todas las comodidades necesarias para tu descanso, desde conexión WiFi hasta una cocina equipada, este espacio te ofrece la oportunidad de relajarte y recargar energías. Disfruta del confort del aire acondicionado, agua caliente/fria en el baño, una cama y sofá cama para tu comodidad, televisión con cable , y toallas y sobrecama para tu conveniencia.

apartment-studio-kitchen-wifi6-tv-comfort-quiet
welcome to my home, designed especially for you! I tell you that our studio apartment cost with its private bathroom,very comfortable, a super comfortable double bed,with its air conditioning, a kitchen, a refrigerator. It has a digital lock for added security. 🙂 if you come for work we have the ideal table so you can work comfortable,the place is centrally located,very quiet and is just steps from the Este coast.. (business and tourist center). If you are interested, you can rent a car!

Large Private Residence in an Excellent Area
House in the best areas of the country. Very quiet street, downtown, near restaurants, pharmacies, malls among others. Large comfortable residence for groups or families. Private parking for up to 2 cars 4 Spacious bedrooms, 2 comfortable studios, living room, breakfast room, large terrace. *Opcion Kosher Disponible* House in one of the best area of the country. Very quiet street, central, close to restaurants, pharmacies, mall and more. Large comfortable residence for groups.

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Entire house, pool table, jacuzzi, private rooftop
¡Bienvenido a Casa Compadre, tu hogar ideal en el histórico Casco Viejo de Panamá! Esta espaciosa y elegante casa cuenta con 4 cómodas habitaciones y capacidad para hasta 10 personas. Perfecta para grupos o familias, ofrece una sala de billar para el entretenimiento, espacios bien decorados y todas las comodidades para una estancia inolvidable. Disfruta de una estadía inolvidable en un ambiente acogedor y completamente equipado.

Casa Urbana by SS • 3BR cozy Stay Near Airpt & PTY
Relax and recharge in this bright, modern 3-bedroom home in Don Bosco—one of Panama City’s safest and most convenient neighborhoods. Just 10 min from Tocumen Airport and 5 min to the Metro. 300 Mbps Wi-Fi, A/C in every room, full kitchen, washer/dryer, Smart TV, and gated parking. A mini market is right in front, malls nearby, and the city just 20 min away. Perfect for families, groups, or business stays.

Exceptional three-story building with sea view
This stunning three-story property, located in Casco Viejo, boasts a terrace with a sea view. Designed with a focus on elegance and relaxation, the house features spacious and well-lit interiors adorned with modern and high-quality decor. The strategic location of the house allows for breathtaking views from the terrace, offering a unique blend of luxury and relaxation in a historic and picturesque setting.

Private Studio 10 Min from the Airport!
Entire apartment 10 minutes from the airport! The apartment is fully furnished including appliances and kitchen items, toiletries, dining room, work table and more. Just a few minutes walk from the SAN ANTONIO METRO Station, restaurants, shopping malls, laundries, supermarkets and pharmacies. We offer tours to San Blas to make the most of your trip. Our house is your house in Panama 🇵🇦

Golden Space | By Paradox
PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.
Popular amenities for Panama City house rentals
House rentals with a pool

Luxury Home with Pool in the Best Neighborhood

house 2 bedrooms, 2, kitchen, dining room, in ancon

A beautiful apartment with a swimming pool, BBQ area, and gym

Beautiful house in Brisas del Golf

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

House of the waterfalls

Airbnb - Vacation

Your country house, Menus de la Montaña, awaits you.
Weekly house rentals

HOUSE Panama City Albrook 3 story house 3 bedroom

Modern and minimalist Altos de Cerro Azul

A complete and cozy house near Tocumen Airport

LovelyviewPty House 15 minutes away from the airport

Cabin in Cerro Azul with Forest View

My Blue Escape

Hello Panama! Brisas del Golf

Spacious & cozy 4 bedroom home.
Private house rentals

2 bedroom apartment in the heart of Panama

Country house in Altos de Cerro Azul

A nice house equipped for rest or home office

Specious house that can accommodate up to seven

Family House | 4 floors | BBQ | 20 Pax | Views

Live in nature 2

Residence in Panama

Oceanfront views/access w/ Pool, Privacy & Space
Quick stats about house rentals in Panama City

Total vacation rentals
Explore 470 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,089 GYD per night before taxes and fees

Verified guest reviews
Over 7,270 verified reviews to help you choose

Family-friendly vacation rentals
180 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 160 rentals that welcome pets

Vacation rentals with a pool
90 properties feature pools

Rentals with dedicated workspaces
220 properties have a dedicated workspace

Wi-Fi availability
430 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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