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Apartment vacation rentals in Panamá Province

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Panamá Province

Guests agree: these apartments are highly rated for location, cleanliness, and more.

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Superhost
Apartment in Panamá
4.92 out of 5 average rating, 168 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Top guest favorite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Apartment in Panama City
5 out of 5 average rating, 83 reviews

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

Guest favorite
A spacious living room features a comfortable brown sofa and an armchair beside a decorative coffee table. Natural light enters through large glass doors draped with sheer curtains, illuminating the warm wood floors and elegant decor.
Apartment in Panama City
4.97 out of 5 average rating, 117 reviews

Luxury Mid-Century Apartment In Casco Viejo

Luxury mid-century one bedroom Boutiqe 72 m2 apartment. Step into the elegant, functional and comfortable place that we offer with love. The apartment located within a beautiful two-floors antique building in the heart of Casco Viejo. The apartment includes a well equipped brand new kitchen, a dining area and a spacious living room, also a balcony with a view of the lively streets below. The tranquil bedroom has an ensuite bathroom and a walking closet that fitting perfectly to your needs.

Top guest favorite
Apartment in Panama City
4.98 out of 5 average rating, 128 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Guest favorite
A modern living area is presented with a light-colored sofa and stylish accent cushions. A glass coffee table is paired with a white armchair and a vibrant blue side table. Floor-to-ceiling windows provide a clear view of the ocean and allow natural light to brighten the space.
Apartment in Panamá
4.79 out of 5 average rating, 141 reviews

Ocean View Apt in Panama, Yoo&Arts

Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

Top guest favorite
Apartment in Panamá
4.97 out of 5 average rating, 37 reviews

Walk to Everything | Luxury Stay in Casco Viej

Wake up overlooking one of the last historic bastions of Casco Viejo, sip your morning cofee on a private balcony, and step directly into Panama City most vibrant and wakable neighboorhood. Surrounded by colonial architecture, charming plazas, and a vibrant culinary scene, this space invites you to experience Panama with style and tranquility. Ideal for those seeking an exclusive, walkable, and characterful environment in one of the city's most iconic areas.

Guest favorite
A spacious living area is highlighted by a large sectional sofa and a low wooden shelf displaying modern decor. Glass doors open to a balcony showcasing outdoor seating, with natural light illuminating the room. The tile floor adds a warm touch to the ambiance.
Apartment in Panamá
4.82 out of 5 average rating, 137 reviews

Stunning Terrace Among Ruins in Casco Viejo

Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.

Top guest favorite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Apartment in Panamá
4.99 out of 5 average rating, 200 reviews

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Guest favorite
Apartment in Panamá
4.93 out of 5 average rating, 59 reviews

Colonial style with calicanto and private balcony

Welcome to a cozy apartment where the charm of the calicanto walls blends with warm details and a perfect balcony to enjoy the atmosphere and the view of the Old Town. We have a prime location on one of the main avenues of the Casco. From here you can easily access historic sites, restaurants, cafes, bars and charming spots. The idea is for you to arrive, feel comfortable, and enjoy the city at your own pace, whether alone, as a couple, or as a family.

Top guest favorite
An expansive infinity pool reflects the skyline of Panama City and the nearby bay. Lounge chairs are arranged neatly along the poolside, allowing for relaxation while enjoying the panoramic views of the surrounding area.
Apartment in Panama City
4.93 out of 5 average rating, 134 reviews

Impressive ocean and Panama City views

Enjoy a unique experience, a modern apartment with its own style, where every sunrise and sunset becomes a show. Enjoy breathtaking views of Panama City, the bay, and the Old Town from the comfort of your home. Unbeatable Location Located just 5 minutes from the charming Casco Viejo and the famous seafood market, and 10 minutes from the banking area. In addition, you will have a metro station and several bus stops just a few steps from the building

Guest favorite
Apartment in Panamá
4.89 out of 5 average rating, 102 reviews

Modern, central and comfortable (104)

Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama queen, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad! 🧳 Estancias largas bienvenidas (descuentos aplicables)

Guest favorite
A cozy sitting area is highlighted by a large window offering views of the vibrant plaza and cathedral. Two comfortable armchairs are positioned beside a small coffee table on a textured rug. Natural light fills the space, enhancing the warm tones of the wooden floor.
Apartment in Panama City
4.91 out of 5 average rating, 125 reviews

The best view of the Old Town

Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Popular amenities for Panamá Province apartment rentals

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