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Family-friendly vacation rentals in Panama City

Find and book unique family-friendly homes on Airbnb

Quick stats about vacation rentals that are family-friendly in Panama City

  • Total vacation rentals

    Explore 1,780 vacation rentals in Panama City

  • Nightly prices starting at

    Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

  • Verified guest reviews

    Over 54,870 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 760 rentals that welcome pets

  • Vacation rentals with a pool

    1,050 properties feature pools

  • Rentals with dedicated workspaces

    1,110 properties have a dedicated workspace

  • Wi-Fi availability

    1,720 of Panama City vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Top-rated family-friendly rentals in Panama City

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Superhost
An indoor garden is showcased, featuring lush greenery and soft lighting. A glass roof allows natural light to illuminate the space, which is accented by warm-toned stone walls. Two stylish chairs are positioned nearby, creating a comfortable seating area.
Condo in San Felipe
4.88 out of 5 average rating, 150 reviews

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES

Spectacular Duplex penthouse in Panama's historic district, 265 M2 with balconies, private outdoor terraces, an interior garden living room, a dining room, 3 bedrooms (+ sofa bed in studio), recently renovated with a Loft concept, exclusive unique and comfortable design, in the best area of the historic district, perfect for relaxing and unwinding, kitchen, dishwasher, living room with washing machine, shared pool, elevator, 24-7 doorman, children who cannot swim are not allowed, a wide variety of leisure activities in the area.

Guest favorite
Apartment in San Felipe
4.96 out of 5 average rating, 260 reviews

In the heart of Casco, remodeled and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Guest favorite
A serene river flows beside the property, surrounded by lush greenery and rocky formations. Trees and tropical plants frame the scene, while small cascades create a gentle noise, enhancing the tranquil atmosphere of the natural landscape.
Cottage in Panama City
4.92 out of 5 average rating, 122 reviews

Round House River Dreams Cerro Azul

Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.

Top guest favorite
Apartment in San Felipe
4.98 out of 5 average rating, 130 reviews

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Guest favorite
A spacious living area is highlighted by a large sectional sofa and a low wooden shelf displaying modern decor. Glass doors open to a balcony showcasing outdoor seating, with natural light illuminating the room. The tile floor adds a warm touch to the ambiance.
Apartment in San Felipe
4.82 out of 5 average rating, 137 reviews

Stunning Terrace Among Ruins in Casco Viejo

Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.

Top guest favorite
The private outdoor pool is set against a backdrop of lush greenery and the home's elegant architecture. Comfortable seating arrangements are positioned nearby on the pool deck, inviting relaxation. Large windows reflect natural light, enhancing the spaciousness of the surrounding area.
Villa in San Francisco
4.97 out of 5 average rating, 119 reviews

Beautiful House in Panama w/ King Beds + Pool

Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Top guest favorite
A cozy living area features a bright yellow armchair beside a sleek media console. A modern television is mounted above the console, which displays green foliage. The floor is adorned with a patterned rug, while the textured stone wall adds a rustic charm to the space.
Place to stay in San Felipe
4.95 out of 5 average rating, 101 reviews

Loft in Casco Antiguo, Joya Colonial

Welcome to a space where history, design and comfort merge in one of Panama's most iconic neighborhoods. This apartment, located in the heart of the Old Town, immerses you in the rich colonial culture and architecture, while offering you all the modern amenities for an unforgettable stay. ✔ Spacious ✔ Classic-modern design ✔ Equipped kitchen ✔ Private balcony ✔ Dreamy master bedroom ✔ High-speed WiFi and Smart TV ✔ An unbeatable location

Superhost
Apartment in Panama City
4.75 out of 5 average rating, 120 reviews

Apartment in the Causeway Amador

Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family

Superhost
A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.
Apartment in Bella Vista
4.91 out of 5 average rating, 329 reviews

Modern apt ocean view in heart of Panamá yoo tower

This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.

Guest favorite
A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.
Loft in San Felipe
4.93 out of 5 average rating, 124 reviews

Loft 3b Old Town Best! It's 150 m2 (492 feet)

Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Superhost
Guest suite in Panama City
4.97 out of 5 average rating, 111 reviews

Late check-in • up to 6 guests •10 m to Airpt

Only 10 min from Tocumen Airport (PTY) Ideal for: •Layovers and early flights •Late-night arrivals •Families and groups up to 6 •Business trips Entire apartment: •2 double beds + additional bedroom (for larger groups) •Living room, dining area & workspace •A/C • Fast WiFi • Hot water •Fully equipped kitchen •Airport transportation (pre booking) •Gated community •Easy check-in with instructions •Quick assistance upon arrival

Guest favorite
A serene courtyard features a small pool surrounded by terracotta tiles and smooth wooden planks. Lush green plants are displayed throughout the space, enhancing the tranquil environment. The walls are adorned with original stonework, blending history with nature.
Home in San Felipe
4.79 out of 5 average rating, 129 reviews

Cozy house in Casco Viejo with private pool

Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the center of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Among its most outstanding features is a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

Popular amenities for Panama City family-friendly rentals

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