
Family-friendly vacation rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Panama City

Total vacation rentals
Explore 1,780 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

Verified guest reviews
Over 54,870 verified reviews to help you choose

Pet-friendly vacation rentals
Find 760 rentals that welcome pets

Vacation rentals with a pool
1,050 properties feature pools

Rentals with dedicated workspaces
1,110 properties have a dedicated workspace

Wi-Fi availability
1,720 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Spectacular duplex penthouse in Panama's Old Town, 265 m² with balconies, private outdoor terraces, an indoor garden living room, a dining room, 3 bedrooms (+ sofa bed in the studio), recently renovated with a loft concept, an exclusive, unique and comfortable design, in the best area of the Old Town, perfect for relaxing and unwinding. It has a kitchen, dishwasher, laundry room with washing machine, shared pool, elevator, 24/7 doorman (the pool is not suitable for children), and a wide variety of entertainment options in the area.
4.88 out of 5 average rating, 150 reviews
In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
4.96 out of 5 average rating, 263 reviews
Family apartment 3 bedrooms pool wifi free parking
Within walking distance of Vía Argentina, and the Vía Argentina Metro stop in the heart of El Cangrejo. Restaurants, supermarkets, shops, coffee shops, pharmacies, Andrés Bello Park, and everything you might need are just a few steps away. Unbeatable location. On a quiet street but close to everything. In El Cangrejo, the neighborhood of choice for visiting foreigners. Family-owned building. Close to all the city's tourist attractions, it's an ideal base for exploring this beautiful city.
4.87 out of 5 average rating, 116 reviews
Spacious 6BR House w/ Pool, Gym & King Beds
Enjoy a spacious private home in the heart of Punta Paitilla, one of Panama City’s most central neighborhoods. Perfect for families and groups, the house features 6 bedrooms, 5.5 bathrooms, 9 beds, a private pool, and plenty of space to relax, comfortably accommodating up to 17 guests. Walk to supermarkets, restaurants, and nearby synagogues, or reach Multiplaza and other popular areas of the city within minutes. A comfortable and convenient home base for enjoying Panama City together.
4.98 out of 5 average rating, 120 reviews
Central Artsy Colonial 2BR Loft with Balcony
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!
4.99 out of 5 average rating, 179 reviews
Stunning Terrace Among Ruins in Casco Viejo
Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.
4.82 out of 5 average rating, 142 reviews
Loft in Casco Antiguo, Joya Colonial
Welcome to a space where history, design and comfort merge in one of Panama's most iconic neighborhoods. This apartment, located in the heart of the Old Town, immerses you in the rich colonial culture and architecture, while offering you all the modern amenities for an unforgettable stay. ✔ Spacious ✔ Classic-modern design ✔ Equipped kitchen ✔ Private balcony ✔ Dreamy master bedroom ✔ High-speed WiFi and Smart TV ✔ An unbeatable location
4.95 out of 5 average rating, 104 reviews
Apartment in the Causeway Amador
Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family
4.75 out of 5 average rating, 121 reviews
Modern apt ocean view in heart of Panamá yoo tower
This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.
4.91 out of 5 average rating, 332 reviews
Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
4.93 out of 5 average rating, 126 reviews
Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance
4.92 out of 5 average rating, 178 reviews
The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
4.92 out of 5 average rating, 131 reviewsPopular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Unique Historic House in Casco
4.95 out of 5 average rating, 179 reviews
New Flat with Ocean + City Views
4.78 out of 5 average rating, 125 reviews
Tropical Paradise at Playa Bonita
4.93 out of 5 average rating, 117 reviews
Ocean View Apt in Panama, Yoo&Arts
4.8 out of 5 average rating, 144 reviews
Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms
4.84 out of 5 average rating, 118 reviews
Mountain Retreat
4.97 out of 5 average rating, 93 reviews
Club House facing the lake with dock, jacuzzi and BBQ
5.0 out of 5 average rating, 6 reviews
YOO Panama | Ocean View Balcony & Resort Pool
4.97 out of 5 average rating, 36 reviewsFamily- and pet-friendly home rentals

Full apartment in Panama
4.97 out of 5 average rating, 166 reviews
Amazing experience 3BR 2BTH Casco Viejo w/Rooftop
4.8 out of 5 average rating, 110 reviews
The View of Casco: Designer Loft with best Balcony
4.98 out of 5 average rating, 134 reviews
k*| Breathtaking Oceanview 1BR in Ave Balboa
4.82 out of 5 average rating, 114 reviews
Aparthotel Sevilla Suites - 4
4.89 out of 5 average rating, 138 reviews
Majestic Cabin in the Mountains
4.88 out of 5 average rating, 78 reviews
Cerro Azul, Country House with Heated Pool.
4.9 out of 5 average rating, 42 reviews
Panoramic Casco Viejo Lookout in The Sands
4.95 out of 5 average rating, 76 reviewsFamily-friendly home rentals with a pool

Ocean View | Rooftop Pool | Luxury Stay
4.97 out of 5 average rating, 97 reviews
Casa Vidal - The Only House in Casco Viejo
4.89 out of 5 average rating, 73 reviews
Luxury apt in Panama City 2 Rooms 3 Baths
5.0 out of 5 average rating, 87 reviews
Ocean and Modern City / The Sands views
4.86 out of 5 average rating, 49 reviews
Ocean View, Panama City
4.94 out of 5 average rating, 17 reviews
Casa Blanca - Private pool, minutes from the city
4.94 out of 5 average rating, 17 reviews
Modern studio with ocean view / central / prime
4.96 out of 5 average rating, 28 reviews
“Modernity and Comfort in the City”
4.97 out of 5 average rating, 86 reviewsDestinations to explore
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