
Family-friendly vacation rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Panama City

Total vacation rentals
Explore 1,780 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

Verified guest reviews
Over 54,870 verified reviews to help you choose

Pet-friendly vacation rentals
Find 760 rentals that welcome pets

Vacation rentals with a pool
1,050 properties feature pools

Rentals with dedicated workspaces
1,110 properties have a dedicated workspace

Wi-Fi availability
1,720 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Round House River Dreams Cerro Azul
Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Late check-in • Solo or groups up to 6 •Shuttle
✈️ Spacious apartment just 10 minutes from Tocumen Airport. Perfect for layovers, early flights, late arrivals, families, and groups of up to 6 guests. 🛏️ Comfortable beds ❄️ Air conditioning 📶 Fast WiFi 🚿 Hot water 🍽️ Fully equipped kitchen 🚐 Airport transportation available 🔐 Easy check-in with step-by-step instructions 🚗 Safe gated community 📍 Great location for layovers, San Blas tours, and short stays. 💬 Fast communication before and during your stay.

Ocean View Apt in Panama, Yoo&Arts
Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

Colonial style with calicanto and private balcony
Welcome to a cozy apartment where the charm of the calicanto walls blends with warm details and a perfect balcony to enjoy the atmosphere and the view of the Old Town. We have a prime location on one of the main avenues of the Casco. From here you can easily access historic sites, restaurants, cafes, bars and charming spots. The idea is for you to arrive, feel comfortable, and enjoy the city at your own pace, whether alone, as a couple, or as a family.

Modern apt ocean view in heart of Panamá yoo tower
This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.

Moderno, céntrico y cómodo (104)
Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama queen, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad! 🧳 Estancias largas bienvenidas (descuentos aplicables)

The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Most Beautiful Loft in the Heart of Casco Viejo
Discover Casco Viejo from this beautiful loft, perfectly located. Casco Viejo, UNESCO World Heritage Site, known for its colonial buildings, and iconic streets. This vibrant neighborhood offers many restaurants, coffee places, museums, and an exciting night life. Just steps from Fonda Lo Que Hay, ranked among Latin America's Top 50 culinary destinations. Close to MYKA Greek Yogurt and the iconic La Compañía Hotel.

CASA SAEMA "D" -Design Apt, Casco Viejo Panama
Beautiful Apt "D" in Panama Casco Antiguo, renovated with top quality materials, exclusive and comfortable design, in the best area of Casco Viejo, perfect for relaxing and unwinding, kitchen with dishwasher and washing machine. The building has a shared pool in the central courtyard, 24-7 doorman, a wide variety of leisure activities in the area, children who cannot swim are not allowed.
Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Luxurious country house, pleasant climate, with fireplace, jacuzzi, pool table, barbecue area, fire pit and more...

New Flat with Ocean + City Views

Unique Historic House in Casco

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms

Tropical Paradise at Playa Bonita

Mountain Retreat

Cerro Azul Mountain Retreat un hogar mágico.

Vive la Experiencia Wanders And Yoo en Panamá
Family- and pet-friendly home rentals

Studio apartment in the heart of Casco

Full apartment in Panama

Beautiful Apartment on High Floor, Beautiful Views

Luxury apartment in downtown Panama, banking area

Aparthotel Sevilla Suites - 4

Beautiful House in Panama w/ King Beds + Pool

Tropical Delight

Self-Contained Apartment at Albrook Field
Family-friendly home rentals with a pool

Walk to Everything | Luxury Stay in Casco Viej

Bright Designer Residence w/ Skylight + Rooftop

Luxury apt in Panama City 2 Rooms 3 Baths

"Arrive as guests. Leave feeling at home".

Panoramic Ocean View | The Sands

Refugio Moderno | Vista lateral al Mar | 4 huesp.

GreatCanal-Front Luxury 3BR | City & Golf View 401

Villas La Fontana Spacious ApartaSuite - Pool 104
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- Things to do Panama
- Landmarks Panama
- Water sports Panama
- Nature and outdoors Panama
- Food tours Panama
- Sports activities Panama
- Tastings Panama
- Sightseeing Panama
- Wildlife Panama
- Outdoors Panama
- Cultural tours Panama
- Tours Panama
- Food and drink Panama
- Art and culture Panama
- Cooking Panama







