Family-friendly vacation rentals in Panama City

In the heart of Casco, remodeled and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Kitchen · Family · Parking

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Indoor spaces · Kitchen · Check-in

Round House River Dreams Cerro Azul

Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.

Indoor spaces · Kitchen · Access

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES

Espectacular ático Duplex en Panamá Casco antiguo, de 265 M2 con balcones, terrazas privadas exterior, cuenta con una salón jardín interior, un comedor, 3 hab. (+ sofá cama en studio), recientemente reformado con concepto Loft, diseño exclusivo único y confortable, en la mejor zona del Casco viejo, perfecto para relajarse y desconectar, cocina , lavavajilla, sala con lavadora. piscina compartida, asc, portero 24-7, no se permiten niños que no sepan nadar, gran variedad de ocio en la zona.

Kitchen · Family · Layout

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Kitchen · Family · Walkability

The View of Casco: Designer Loft with best Balcony

Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! ​Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. ​You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Family · Kitchen · Location

Late check-in • Solo or groups up to 6 •Shuttle

✈️ Spacious apartment just 10 minutes from Tocumen Airport. Perfect for layovers, early flights, late arrivals, families, and groups of up to 6 guests. 🛏️ Comfortable beds ❄️ Air conditioning 📶 Fast WiFi 🚿 Hot water 🍽️ Fully equipped kitchen 🚐 Airport transportation available 🔐 Easy check-in with step-by-step instructions 🚗 Safe gated community 📍 Great location for layovers, San Blas tours, and short stays. 💬 Fast communication before and during your stay.

Family · Indoor spaces · Wifi

Beautiful House in Panama w/ King Beds + Pool

Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Kitchen · Family · Decor

Loft 3b Old Town Best! It's 150 m2 (492 feet)

Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Indoor spaces · Family · Amenities

The best view of the Old Town

Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Indoor spaces · Kitchen · Getting around

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Kitchen · Family · Hospitality

Amazing Loft with the Best view of Casco viejo for

Beautiful loft located in the center of Casco Antiguo, the most touristic area of Panama. This spacious loft comfortably accommodates up to 6 guests, making it perfect for families or groups of friends. Come, enjoy and relax in this impressive loft, featuring an incredible view of the Panama Cathedral. You can easily visit museums, bars, restaurants, and historic churches located just a few meters away.

Kitchen · Indoor spaces · Nearby