
Family-friendly vacation rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Panama City

Total vacation rentals
Explore 1,780 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

Verified guest reviews
Over 54,870 verified reviews to help you choose

Pet-friendly vacation rentals
Find 760 rentals that welcome pets

Vacation rentals with a pool
1,050 properties feature pools

Rentals with dedicated workspaces
1,110 properties have a dedicated workspace

Wi-Fi availability
1,720 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Spectacular Duplex penthouse in Panama's historic district, 265 M2 with balconies, private outdoor terraces, an interior garden living room, a dining room, 3 bedrooms (+ sofa bed in studio), recently renovated with a Loft concept, exclusive unique and comfortable design, in the best area of the historic district, perfect for relaxing and unwinding, kitchen, dishwasher, living room with washing machine, shared pool, elevator, 24-7 doorman, children who cannot swim are not allowed, a wide variety of leisure activities in the area.
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In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
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Round House River Dreams Cerro Azul
Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.
KitchenIndoor spacesBackyard

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
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Stunning Terrace Among Ruins in Casco Viejo
Welcome to your Casco Viejo retreat! This spacious apartment, perfect for up to 8 guests, offers a unique blend of modern comfort and historic charm in Panama City’s most iconic neighborhood. Located in the heart of Casco Viejo. The highlight of this beautiful space is the stunning terrace nestled among historic ruins, where you can relax, enjoy a meal, or simply take in the timeless atmosphere. This is more than a stay – it’s an unforgettable experience.
FamilyIndoor spacesOutdoor spaces

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.
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Loft in Casco Antiguo, Joya Colonial
Welcome to a space where history, design and comfort merge in one of Panama's most iconic neighborhoods. This apartment, located in the heart of the Old Town, immerses you in the rich colonial culture and architecture, while offering you all the modern amenities for an unforgettable stay. ✔ Spacious ✔ Classic-modern design ✔ Equipped kitchen ✔ Private balcony ✔ Dreamy master bedroom ✔ High-speed WiFi and Smart TV ✔ An unbeatable location
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Apartment in the Causeway Amador
Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family
Indoor spacesKitchenHospitality

Modern apt ocean view in heart of Panamá yoo tower
This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.
Indoor spacesKitchenHot tub

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
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Late check-in • up to 6 guests •10 m to Airpt
Only 10 min from Tocumen Airport (PTY) Ideal for: •Layovers and early flights •Late-night arrivals •Families and groups up to 6 •Business trips Entire apartment: •2 double beds + additional bedroom (for larger groups) •Living room, dining area & workspace •A/C • Fast WiFi • Hot water •Fully equipped kitchen •Airport transportation (pre booking) •Gated community •Easy check-in with instructions •Quick assistance upon arrival
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Cozy house in Casco Viejo with private pool
Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the center of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Among its most outstanding features is a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.
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Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts
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Unique Historic House in Casco
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Tropical Paradise at Playa Bonita
FamilyIndoor spacesLocation

New Flat with Ocean + City Views
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Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms
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Mountain Retreat
FamilyKitchenHot tub

Relaxing sea view | Pool | AC | Ideal location
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Cerro Azul Mountain Retreat un hogar mágico.
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Family- and pet-friendly home rentals

Aparthotel Sevilla Suites - 4
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k*| Breathtaking Oceanview 1BR in Ave Balboa
KitchenIndoor spacesAccess

Full apartment in Panama
Indoor spacesKitchenSolo travel

Majestic Cabin in the Mountains
Indoor spacesKitchenQuiet

Cerro Azul, Country House with Heated Pool.
FamilyKitchenView

Executive apartment on Avenida Balboa
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Private parking & rooftop | Studio Casco Center
Indoor spacesFamilyWifi

Luxury Centric 2BR Apartment in Casco Viejo
KitchenIndoor spacesHospitality
Family-friendly home rentals with a pool

The Sands, Beautiful Apartment
FamilyIndoor spacesDecor

Spectacular views, pool, and ideal location
KitchenIndoor spacesLocation

LUXURY APT/Ocean View & Rooftop
Indoor spacesKitchenParking

The Gray Calle 50 is very central, 5 minutes from the station.
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Apartment in Panama City 3 bedrooms 4 bathrooms
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The Sands Modern Oceanfront Apartment Panama City!
Indoor spacesAccuracyLocation

Ocean View | Rooftop Pool | Luxury Stay
FamilyIndoor spacesAmenities

Panoramic Ocean View | The Sands
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