
Family-friendly vacation rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Panama City

Total vacation rentals
Explore 1,780 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

Verified guest reviews
Over 54,870 verified reviews to help you choose

Pet-friendly vacation rentals
Find 760 rentals that welcome pets

Vacation rentals with a pool
1,050 properties feature pools

Rentals with dedicated workspaces
1,110 properties have a dedicated workspace

Wi-Fi availability
1,720 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Yoo Panama 36th floor waterfront apartment
Elegant, comfortable, modern and luxurious apartment located in the best building in Panama, with ocean views from the 36th floor. It has the best social areas designed by renowned designer Philippe Starck. Fully furnished to make your stay a unique experience. The building has a gym, swimming pool, play areas for adults and children, squash court, 3 excellent restaurants, and a supermarket. Located in a privileged location in the heart of Panama's financial center.

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Modern apt ocean view in heart of Panamá yoo tower
This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Cozy house in Casco Viejo with private pool
Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the center of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Among its most outstanding features is a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

Private guest house in Ancón
Enjoy the simplicity of this cozy, quiet, and centrally-located accommodation. Close to places of interest such as the Panama Canal Administration building, Amador Causeway, Albrook Mall, and several restaurants. Personally decorated to provide comfort... large windows in the bedroom provide natural lighting and a view of the garden and green area through the windows; yet it maintains the desired privacy and tranquility.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Amazing Loft with the Best view of Casco viejo for
Beautiful loft located in the center of Casco Antiguo, the most touristic area of Panama. This spacious loft comfortably accommodates up to 6 guests, making it perfect for families or groups of friends. Come, enjoy and relax in this impressive loft, featuring an incredible view of the Panama Cathedral. You can easily visit museums, bars, restaurants, and historic churches located just a few meters away.

CASA SAEMA "C" -Design Apt, Casco Viejo Panama
Beautiful apartment in Panama's historic district, renovated with premium materials, exclusive and comfortable design, in the best area of the historic district, perfect for relaxing and unwinding, kitchen with dishwasher and washing machine. The building has a shared pool in the central courtyard, 24-7 doorman, a wide variety of leisure activities in the area, children who cannot swim are not allowed.

Patty’s Charming Serene Studio in Casco Viejo
Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen aside from the main living space. It is spacious, comfortable and tastefully decorated!
Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts

New Flat with Ocean + City Views

Luxurious country house, pleasant climate, with fireplace, jacuzzi, pool table, barbecue area, fire pit and more...

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms

Tropical Paradise at Playa Bonita

Mountain Retreat

Luxury Apartment With Private Beach And Sea View

2BR King Suite Ocean View, Casco, Canal 500MB WIFI
Family- and pet-friendly home rentals

Impressive ocean and Panama City views

Round House River Dreams Cerro Azul

Beautiful Apartment on High Floor, Beautiful Views

Private parking & rooftop | Studio Casco Center

Panoramic Casco Viejo Lookout in The Sands

Villas La Fontana Spacious ApartaSuite - Pool 102

Sea view | Modern Design | 2BR | Spacious Apt

Amazing loft with Casco charm in the best location
Family-friendly home rentals with a pool

Apto 4 min from Tocumen Airport | 24-hr check-in

Spectacular views, pool, and ideal location

Walk to Everything | Luxury Stay in Casco Viej

Apartment in Panama City 3 bedrooms 4 bathrooms

The Sands | Modern 1BR w/ Partial Ocean View

Your Space in the City

Old Town & Ocean View

Spectacular Bay View • 1BR • Pool/Gym and +
Destinations to explore
- Cahuita Vacation rentals
- Bahía Ballena Vacation rentals
- Coveñas Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Bocas del Toro Province Vacation rentals
- San Andrés Vacation rentals
- Uvita Vacation rentals
- Rio Hato Vacation rentals
- Boquete Vacation rentals
- El Valle Vacation rentals
- Valle de Antón Vacation rentals
- Nueva Gorgona Vacation rentals
- Waterfront rentals Panama City
- House rentals Panama City
- Rentals with outdoor seating Panama City
- Rentals with a fireplace Panama City
- Rentals with lake access Panama City
- Serviced apartment rentals Panama City
- Rentals with a patio Panama City
- Rentals with a sauna Panama City
- Fitness-friendly rentals Panama City
- Rentals with a fire pit Panama City
- Pet-friendly rentals Panama City
- Apartment rentals Panama City
- Beachfront rentals Panama City
- Boutique hotels Panama City
- Rentals with an EV charger Panama City
- Bed and breakfasts Panama City
- Rentals with a hot tub Panama City
- Hotel rooms Panama City
- Rentals with a home theater Panama City
- Guesthouse rentals Panama City
- Smoking-friendly rentals Panama City
- Cabin rentals Panama City
- Hostel rentals Panama City
- Condo rentals Panama City
- Townhouse rentals Panama City
- Private suite rentals Panama City
- Rentals with an accessible height bed Panama City
- Loft rentals Panama City
- Rentals with beach access Panama City
- Rentals with a washer and dryer Panama City
- Rentals with breakfast Panama City
- Rentals with pools Panama City
- Villa rentals Panama City
- Family-friendly rentals Panamá Province
- Family-friendly rentals Panama
- Things to do Panama City
- Nature and outdoors Panama City
- Art and culture Panama City
- Tours Panama City
- Sports activities Panama City
- Sightseeing Panama City
- Food and drink Panama City
- Things to do Panamá Province
- Sports activities Panamá Province
- Nature and outdoors Panamá Province
- Tours Panamá Province
- Sightseeing Panamá Province
- Food and drink Panamá Province
- Art and culture Panamá Province
- Things to do Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Tours Panama
- Food and drink Panama
- Art and culture Panama





