
Family-friendly vacation rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Panama City

Total vacation rentals
Explore 1,780 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,088 GYD per night before taxes and fees

Verified guest reviews
Over 54,870 verified reviews to help you choose

Pet-friendly vacation rentals
Find 760 rentals that welcome pets

Vacation rentals with a pool
1,050 properties feature pools

Rentals with dedicated workspaces
1,110 properties have a dedicated workspace

Wi-Fi availability
1,720 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Modern apt ocean view in heart of Panamá yoo tower
This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Flexible check-in • 10 minutes from Tocumen Airport
Perfect for stopovers, nocturnal or early flights and short stays. Stay just 10 minutes from Tocumen Airport • Easy and flexible self check-in (subject to availability) Private 🛏️ studio for up to 2 guests ❄️ A/C 📶 Fast Wi-Fi 🚿 Shower with hot water 🍳 Equiped kitchen Safe residential 🔒 community Airport 🚗 transportation available (subject to reservation) Ideal for travelers in transit, couples or short stays without hassle.

Moderno, céntrico y cómodo (104)
Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama queen, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad! 🧳 Estancias largas bienvenidas (descuentos aplicables)

Cozy house in Casco Viejo with private pool
Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the center of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Among its most outstanding features is a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

CASA SAEMA "C" -Design Apt, Casco Viejo Panama
Beautiful apartment in Panama's historic district, renovated with premium materials, exclusive and comfortable design, in the best area of the historic district, perfect for relaxing and unwinding, kitchen with dishwasher and washing machine. The building has a shared pool in the central courtyard, 24-7 doorman, a wide variety of leisure activities in the area, children who cannot swim are not allowed.

Patty’s Bay View Home @ the Causeway with bikes
Beautiful and well-appointed spacious 1-bedroom condo featuring a large bathroom & fully stocked kitchen. Gorgeous Ocean views onto Casco Viejo, downtown Skyline & lush hills of Ancon as a background. Enjoy the Canal views, with ships, from the common roof top terraces. Its close location by the Causeway, Casco Viejo & down town makes it the perfect "pied à terre".

Exclusivo Ocean View 2BR/2BATH/Sky High & Rooftop.
Luxury modern apartment on the Costera Cinta. Ideal for executives, couples, or families. Spacious bedroom with ocean views, spacious bathroom, elegant design and modern appliances. Amenities: 24/7 security, gym, swimming pools, 4 restaurants, bar and Sky Lounge. Close to supermarkets and a great gastronomic offer. Panama City, Panama.
Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts

New Flat with Ocean + City Views

Unique Historic House in Casco

Tropical Paradise at Playa Bonita

Luxurious country house, pleasant climate, with fireplace, jacuzzi, pool table, barbecue area, fire pit and more...

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms

Mountain Retreat

Cerro Azul Mountain Retreat un hogar mágico.
Family- and pet-friendly home rentals

Cozy 2 Bedroom w/ Splash Pool

Full apartment in Panama

k*| Delightful 1 BR w/King Bed in Calle 50

Luxury apartment in downtown Panama, banking area

Apartment in the Causeway Amador

Round House River Dreams Cerro Azul

Private parking & rooftop | Studio Casco Center

Luxury Apartment | Walk to Restaurants & Shops
Family-friendly home rentals with a pool

YOO Eclectic & luxury seafront / 2BR / 45th floor

Beautiful Apartment -3 guests with Balcony

Bright Designer Residence w/ Skylight + Rooftop

Luxury apt in Panama City 2 Rooms 3 Baths

Walk to Everything | Luxury Stay in Casco Viej

Panoramic Ocean View | The Sands

Ocean View, Panama City

Old Town & Ocean View
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