
Family-friendly vacation rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Panama City

Total vacation rentals
Explore 1,780 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

Verified guest reviews
Over 54,870 verified reviews to help you choose

Pet-friendly vacation rentals
Find 760 rentals that welcome pets

Vacation rentals with a pool
1,050 properties feature pools

Rentals with dedicated workspaces
1,110 properties have a dedicated workspace

Wi-Fi availability
1,720 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Modern apt ocean view in heart of Panamá yoo tower
Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Ocean View Apt in Panama, Yoo&Arts
Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Impressive ocean and Panama City views
Enjoy a unique experience, a modern apartment with its own style, where every sunrise and sunset becomes a show. Enjoy breathtaking views of Panama City, the bay, and the Old Town from the comfort of your home. Unbeatable Location Located just 5 minutes from the charming Casco Viejo and the famous seafood market, and 10 minutes from the banking area. In addition, you will have a metro station and several bus stops just a few steps from the building

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

Cozy house in Casco Viejo with private pool
Historic accommodation in the heart of the Old Town Enjoy a unique experience in this accommodation located in the center of the Old Town. The property has been carefully restored several times by renowned Panamanian architects, including Sebastián Paniza. Among its most outstanding features is a historic well within the property, as well as original walls and floors that preserve the spirit and authenticity of the place.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Amazing Loft with the Best view of Casco viejo for
Beautiful loft located in the center of Casco Antiguo, the most touristic area of Panama. This spacious loft comfortably accommodates up to 6 guests, making it perfect for families or groups of friends. Come, enjoy and relax in this impressive loft, featuring an incredible view of the Panama Cathedral. You can easily visit museums, bars, restaurants, and historic churches located just a few meters away.

Patty’s Charming Serene Studio in Casco Viejo
Best location by the “El Rey" Supermarket...Casco's only grocery store! Prime location steps away from restaurants, bars, cafes, plazas and great little breakfast places with the lovely water front promenade around the corner making it the perfect “pied-à-terre!” The studio has a fully stocked kitchen aside from the main living space. It is spacious, comfortable and tastefully decorated!
Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Mountain Retreat

Luxury Apartment With Private Beach And Sea View

New Flat with Ocean + City Views

Unique Historic House in Casco

Tropical Paradise at Playa Bonita

Premium APT | Downtown | Design, Comfort, Parking

2BR King Suite Ocean View, Casco, Canal 500MB WIFI

Luxurious country house, pleasant climate, with fireplace, jacuzzi, pool table, barbecue area, fire pit and more...
Family- and pet-friendly home rentals

Elegant Apt in Costa del Este. Premium Amenities

Ocean view | Infinity pool + POIN Panama

Lovely & Cozy central apartment in Casco Viejo

Private parking & rooftop | Studio Casco Center

Tropical Delight

La Fontana Spacious ApartaSuite - Pool 102

Luxury apartment in downtown Panama, banking area

Where I'm happy in Panama City
Family-friendly home rentals with a pool

Ocean View Luxury | 4 Guests | 1 BR | 1 Bath

GreatCanal-Front Luxury 3BR | City & Golf View 401

Old Town & Ocean View

Spectacular views, pool, and ideal location

Walk to Everything | Luxury Stay in Casco Viej

Yoo Panama 36th floor waterfront apartment

Apartment in Panama City 3 bedrooms 4 bathrooms

The Sands | Modern 1BR w/ Partial Ocean View
Destinations to explore
- Cahuita Vacation rentals
- Bahía Ballena Vacation rentals
- Coveñas Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Bocas del Toro Province Vacation rentals
- San Andrés Vacation rentals
- Uvita Vacation rentals
- Rio Hato Vacation rentals
- Boquete Vacation rentals
- El Valle Vacation rentals
- Valle de Antón Vacation rentals
- Nueva Gorgona Vacation rentals
- Rentals with a fireplace Panama City
- Rentals with lake access Panama City
- Serviced apartment rentals Panama City
- Rentals with a patio Panama City
- Rentals with a sauna Panama City
- Fitness-friendly rentals Panama City
- Rentals with a fire pit Panama City
- Pet-friendly rentals Panama City
- Boutique hotels Panama City
- Apartment rentals Panama City
- Beachfront rentals Panama City
- Rentals with an EV charger Panama City
- Bed and breakfasts Panama City
- Rentals with a hot tub Panama City
- Hotel rooms Panama City
- Rentals with a home theater Panama City
- Guesthouse rentals Panama City
- Smoking-friendly rentals Panama City
- Cabin rentals Panama City
- Hostel rentals Panama City
- Townhouse rentals Panama City
- Condo rentals Panama City
- Private suite rentals Panama City
- Rentals with an accessible height bed Panama City
- Loft rentals Panama City
- Rentals with beach access Panama City
- Rentals with breakfast Panama City
- Rentals with pools Panama City
- Villa rentals Panama City
- Waterfront rentals Panama City
- House rentals Panama City
- Family-friendly rentals Panamá Province
- Family-friendly rentals Panama
- Things to do Panama City
- Art and culture Panama City
- Tours Panama City
- Sports activities Panama City
- Sightseeing Panama City
- Food and drink Panama City
- Nature and outdoors Panama City
- Things to do Panamá Province
- Sports activities Panamá Province
- Nature and outdoors Panamá Province
- Tours Panamá Province
- Sightseeing Panamá Province
- Food and drink Panamá Province
- Art and culture Panamá Province
- Things to do Panama
- Nature and outdoors Panama
- Sightseeing Panama
- Tours Panama
- Food and drink Panama
- Art and culture Panama





