
Family-friendly vacation rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Quick stats about vacation rentals that are family-friendly in Panama City

Total vacation rentals
Explore 1,780 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,090 GYD per night before taxes and fees

Verified guest reviews
Over 54,870 verified reviews to help you choose

Pet-friendly vacation rentals
Find 760 rentals that welcome pets

Vacation rentals with a pool
1,050 properties feature pools

Rentals with dedicated workspaces
1,110 properties have a dedicated workspace

Wi-Fi availability
1,720 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

CASA SAEMA -PRESTIGIOUS DUPLEX PENTHOUSE WITH TERRACES
Spectacular Duplex penthouse in Panama's historic district, 265 M2 with balconies, private outdoor terraces, an interior garden living room, a dining room, 3 bedrooms (+ sofa bed in studio), recently renovated with a Loft concept, exclusive unique and comfortable design, in the best area of the historic district, perfect for relaxing and unwinding, kitchen, dishwasher, living room with washing machine, shared pool, elevator, 24-7 doorman, children who cannot swim are not allowed, a wide variety of leisure activities in the area.
KitchenFamilyParking

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
KitchenFamilyAccuracy

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!
KitchenIndoor spacesAir conditioning

Round House River Dreams Cerro Azul
Get away from it all and relax in an idyllic tropical rustic retreat set beside a beautiful river with small cascades in the mountains of Cerro Azul. This spacious 2-story, one bedroom home is ideal for couples, small families or groups, with ample space to sleep 6 to 7 people. The property lies within Charges National Park with all its tropical flora and fauna, blue butterflies, hummingbirds, waterfalls and walking trails at your doorstep. Come experience this unique vacation home destination.
FamilyIndoor spacesBackyard

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
KitchenIndoor spacesView

Late check-in • Solo or groups up to 6 •Shuttle
✈️ Spacious apartment just 10 minutes from Tocumen Airport. Perfect for layovers, early flights, late arrivals, families, and groups of up to 6 guests. 🛏️ Comfortable beds ❄️ Air conditioning 📶 Fast WiFi 🚿 Hot water 🍽️ Fully equipped kitchen 🚐 Airport transportation available 🔐 Easy check-in with step-by-step instructions 🚗 Safe gated community 📍 Great location for layovers, San Blas tours, and short stays. 💬 Fast communication before and during your stay.
Indoor spacesFamilyValue

Ocean View Apt in Panama, Yoo&Arts
Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.
KitchenIndoor spacesComfort

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.
Indoor spacesKitchenCheckout

Modern apt ocean view in heart of Panamá yoo tower
This special place is close to everything, making it easy to plan your visit. Ph Yoo and Arts, located on Av. Balboa, very central This beautiful and modern property has a unique style and an incredible ocean view, high floor, 2 bedrooms, 2.5 full bathrooms, laundry, large terrace, dimmable lights throughout the space, dining room, movie room, workspace, 3 smart TVs, 3 central air conditioners, fully equipped kitchen, modern glassware.
Indoor spacesKitchenHospitality

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
FamilyIndoor spacesCondition

Moderno, céntrico y cómodo (104)
Moderno y acogedor estudio en el corazón de Panamá. Perfecto para explorar el Casco Antiguo, la Cinta Costera y más. Cocina completa, cama queen, sofá cama doble, aire acondicionado, WiFi rápido y baño privado. Ideal para 1–4 personas. Acceso privado, ascensor y check-in autónomo. Rodeado de restaurantes, transporte y sitios turísticos. ¡Tu base ideal para conocer la ciudad! 🧳 Estancias largas bienvenidas (descuentos aplicables)
FamilyIndoor spacesWifi

The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.
Indoor spacesKitchenAccess
Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Luxurious country house, pleasant climate, with fireplace, jacuzzi, pool table, barbecue area, fire pit and more...
FamilyKitchenAir conditioning

Altos de Cerro Azul | AC, Full Kitchen, 2 Rooms
KitchenIndoor spacesTV

New Flat with Ocean + City Views
Indoor spacesFamilyNearby

Unique Historic House in Casco
Indoor spacesKitchenWifi

Tropical Paradise at Playa Bonita
FamilyKitchenPool

Mountain Retreat
Indoor spacesKitchenCheck-in

Cerro Azul Mountain Retreat un hogar mágico.
Indoor spacesKitchenLocation

Vive la Experiencia Wanders And Yoo en Panamá
Indoor spacesTVCheck-in
Family- and pet-friendly home rentals

Luxury apartment in downtown Panama, banking area
Indoor spacesKitchenAccuracy

Beautiful Apartment on High Floor, Beautiful Views
Indoor spacesFamilyWifi

Studio apartment in the heart of Casco
Indoor spacesKitchenNearby

Self-Contained Apartment at Albrook Field
Indoor spacesKitchenAccuracy

Private parking & rooftop | Studio Casco Center
KitchenIndoor spacesAmenities

Panoramic Casco Viejo Lookout in The Sands
KitchenIndoor spacesCondition

Luxury Centric 2BR Apartment in Casco Viejo
KitchenFamilyQuiet

Apartment Casco Antiguo Panama I Walk everywhere
Indoor spacesKitchenBeach
Family-friendly home rentals with a pool

Impressive ocean and Panama City views
Indoor spacesKitchenParks

Walk to Everything | Luxury Stay in Casco Viej
Indoor spacesKitchenCheck-in

Bright Designer Residence w/ Skylight + Rooftop
Indoor spacesWalkabilityAir conditioning

Luxury apt in Panama City 2 Rooms 3 Baths
Indoor spacesKitchenGetting around

Panoramic Ocean View | The Sands
Air conditioningHospitalityGetting around

"Arrive as guests. Leave feeling at home".
FamilyIndoor spacesView

Ocean View, Panama City
Indoor spacesConditionNearby

GreatCanal-Front Luxury 3BR | City & Golf View 401
KitchenIndoor spacesLocation
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- Things to do Panama
- Landmarks Panama
- Water sports Panama
- Nature and outdoors Panama
- Food tours Panama
- Sports activities Panama
- Tastings Panama
- Sightseeing Panama
- Wildlife Panama
- Outdoors Panama
- Cultural tours Panama
- Tours Panama
- Food and drink Panama
- Art and culture Panama
- Cooking Panama







