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Hotels in Panama City

Find and book unique hotels on Airbnb

Quick stats about hotels in Panama City

  • Total vacation rentals

    Explore 190 vacation rentals in Panama City

  • Nightly prices starting at

    Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

  • Verified guest reviews

    Over 5,050 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 30 rentals that welcome pets

  • Vacation rentals with a pool

    80 properties feature pools

  • Rentals with dedicated workspaces

    140 properties have a dedicated workspace

  • Wi-Fi availability

    190 of Panama City vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Panama City rentals

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Top-rated hotels in Panama City

Guests agree: these hotels are highly rated for location, cleanliness, and more.

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Superhost
Hotel room in San Felipe

Deluxe Room Hotel Bardot Boutique

Welcome to Hotel Bardot Boutique, where classic luxury and sophisticated design meet in perfect harmony in the heart of the Old Town. Our 30 m² Deluxe Room has been designed to offer an intimate and elegant experience for two people. It features an imposing canopy bed, golden details and a warm atmosphere that invites absolute rest. The room incorporates a beautiful integrated bathtub, creating a romantic atmosphere that elevates every moment of your stay.

5.0 out of 5 average rating, 3 reviews
A comfortable hotel room features a spacious bed with white linens and a maroon throw blanket. A small table is set with two cups, and a television is mounted on the wall. A lamp provides soft lighting in the corner.
Hotel room in El Cangrejo

Cuarto de hotel #1 a una cuadra del Metro

Disfruta de acceso ràpido a los destinos más populares de Ciudad de Panamà, centros comerciales, restaurantes, y áreas turísticas. Cuarto de hotel con baño privado, aire acondicionado, cable TV, recepciòn con 24 horas de servicio y estacionamientos sujetos a disponibilidad. Cerca de restaurantes y casinos. A una cuadra de la estaciòn del Metro que lo lleva en 10 minutos a Albrook Mall, el Centro Comercial más grande de Panamà.

4.71 out of 5 average rating, 21 reviews
Hotel room in Bella Vista

Elegant King room • Private bathroom • Obarrio

Elegant King room with private bathroom in the heart of Obarrio. Equipped with a king-size bed, air conditioning, fast Wi-Fi, a desk, and a wardrobe. In the room, you'll find a coffee corner with a coffee machine, a kettle, tea, and herbal teas, ideal for relaxing at any time of day. Within easy walking distance to restaurants, supermarkets, cafes, the subway, and main services. Perfect for both vacations and business trips.

5.0 out of 5 average rating, 3 reviews
Hotel room in Panama City

Orho Boutique Hotel free shuttle 15 min Airport

Ideal for stopovers between two connections. Thanks to the free shuttle service included in your booking, Hotel ORHO is the best choice among hotels in the Tocumen International Airport area. An oasis of peace for a real rest after a long journey and the opportunity to recharge. A cozy atmosphere where the courtesy of the staff and the tasteful decoration make this boutique hotel a jewel in the heart of Panama.

5.0 out of 5 average rating, 3 reviews
A spacious room features a double bed with light bedding, complemented by two bedside tables with lamps. A patterned accent wall adds visual interest, while natural light filters through the window, illuminating the polished concrete floor.
Hotel room in Panama City

Bedroom with a private bathroom in downtown Panama

We are an accommodation opened in October 2020 located in downtown Panama City. We have several types of rooms. In this case, it is a room with 1 double bed. We offer continuous reception service, high-speed WiFi, a shared work area, a room with a snack and coffee vending machine, and 24-hour security. Our rooms are fully equipped with a private bathroom with hot water, a desk, air conditioning, and cable TV.

4.67 out of 5 average rating, 164 reviews
Hotel room in San Felipe

Comfort Room

Welcome to your retreat in the heart of the old town! This spacious room in our charming hotel combines historic charm with modern amenities for an unforgettable stay in Panama City. Located in an incredibly central location, you will be within walking distance of the main points of interest such as Historic Centers, Panama Interoceanic Canal Museum, Mola Museum, Restaurants, Nightclubs and restaurants.

4.59 out of 5 average rating, 17 reviews
Hotel room in Bella Vista

Deluxe Adapted for People with Reduced Mobility

Welcome to our adapted room on the first floor of Hotel Mio Panama, designed for people with reduced mobility. With 30 m², it combines an adapted, modern and elegant design. Enjoy comfort and independence, along with a practical setting in the heart of the city. The hotel also offers a gym, restaurant and a rooftop pool. Enjoy an unforgettable experience in a cozy and fully equipped environment.

5.0 out of 5 average rating, 3 reviews
Guest favorite
Hotel room in Panama City

Executive Suite Financial District/Pool·Gym

Elegant suite located in the Megapolis Hotel, in the heart of Panama City. Modern and comfortable space, ideal for business trips or tourism. Strategic location near the Financial District, restaurants, shopping malls, nightlife and tourist attractions of the city. Enjoy access to high-level common areas, pool, gym and amenities that combine meals, rest and entertainment in one place.

4.83 out of 5 average rating, 12 reviews
Guest favorite
A cozy room features a double size bed with striped bedding and a piece of artwork above. A glass-enclosed shower is visible to the right, with a small stool nearby. Soft natural light filters through a sheer curtain, illuminating the space.
Hotel room in San Felipe

Beautiful small loft #3 - double size bed

Enjoy charming "Corcho rooms" in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. "Corcho" is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.

4.78 out of 5 average rating, 81 reviews
A spacious guestroom is featured, showcasing a large bed with crisp white linens and a striped accent throw. A mounted flat-screen TV is positioned on the wall opposite the bed, and a small table with a single chair is placed nearby.
Hotel room in Panama City

Single room for 2 with breakfast included

We are an Executive Hotel, located in the center of the beautiful city of Panama, near the Cinta Costera, Casco Antiguo, the Museum of Biodiversity, the Panama Canal, among other locations. Come and enjoy our services!

4.8 out of 5 average rating, 5 reviews
A comfortable sleeping area features a spacious bed dressed in neutral tones. Wooden headboards are complemented by bedside lamps. Natural light filters in through a large window, covered by light, flowing curtains. A small nightstand is positioned on each side of the bed.
Hotel room in Bella Vista

Your second home in Panama.

Our rooms are located in a prime area in the heart of the city's Financial and Banking sector. We are two blocks away, two stations from the Metro transportation system. 15 minutes from some Shopping Centers.

4.68 out of 5 average rating, 191 reviews
Hotel room in El Cangrejo

Hostal El Prado in El Cangrejo Superior Room

Bella Vista, El Cangrejo, Panama The hostel offers air-conditioned rooms, a wardrobe, a safe, a flat-screen TV, and a private bathroom with a shower. At Hostal EL Prado, rooms include bedding and towels.

5.0 out of 5 average rating, 3 reviews

Popular amenities for Panama City hotels

Destinations to explore