
Hotels in Panama City
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Top-rated hotels in Panama City
Guests agree: these hotels are highly rated for location, cleanliness, and more.

4. Heart of the Old Town: Boutique Apart-Hotel
La Isabela Suites is a Boutique apart-hotel built on the concept of space, elegance and comfort. Located in the heart of Casco Antiguo, only steps from culture, markets, dining, and bars, and with a unique quality of service. La Isabela Suites offers an alternative type of travel, away from the small, standardized and impersonal massive hotel rooms without the inconvenience of a self-catering apartment. Because we understand that the true luxury means not having to worry about anything.

La Husseyenda - Birdwatcher Haven
A Birdwatcher’s and Jungle Paradise nestled in Los Altos de Cerro Azul, this 3-level villa offers breathtaking Lake Alajuela views, stunning sunsets, and endless birdwatching opportunities! Spot hummingbirds, tanagers & toucans from the terrace while howler monkeys call in the distance. Family & pet-friendly with a fenced garden, spacious BBQ, & a fully equipped kitchen. Relax in nature’s paradise—your jungle escape awaits! Make some memories at this unique and family-friendly place.

Very Nice Downtown Panamá Hotel Free Parking
Welcome to the beautiful Aloft Panamá hotel This is a very nice and safe hotel located in the San Francisco area of Panamá with beautiful city views. King or 2 queen based on availability (Feel free to make request prior to booking if you have a preference) All rooms non smoking ($350 fine) No pets allowed Must be 21 with id to checkin Must have credit card for incidentals Checkin time starts at 3pm Checkout time before noon Free Parking Pool Bar/Lounge

Hotel room #3 one block from the Metro.
Disfruta de acceso ràpido a los destinos más populares de Ciudad de Panamà, centros comerciales, restaurantes, y áreas turísticas. Cuarto de hotel con baño privado, aire acondicionado, cable TV, recepciòn con 24 horas de servicio y estacionamientos sujetos a disponibilidad. Cerca de restaurantes y casinos. A una cuadra de la estaciòn del Metro que lo lleva en 10 minutos a Albrook Mall, el Centro Comercial más grande de Panamà.

Desk & Dream Room in flat for work and rest
Disfruta de la comodidad de este alojamiento tranquilo y céntrico en el corazón de San Francisco, tiene escritorio dentro de la habitación para trabajar o estudiar en un ambiente relax, con las demás comodidades incluyendo televisor led HD de 32" Justo en la calle de al lado está el super mercado, farmacia al frente, restaurantes, tiendas de chinitos, panaderías, paradas del metro bus cercanas.

Marinn Place | Deluxe King | Cozy Work & Rest
Located in Panama City’s upscale Financial District near Via España and Bella Vista, Marinn Place offers modern comfort, a rooftop pool, and free valet parking in a vibrant urban setting. The spacious Deluxe Double features two plush queen beds, a separate living/sleeping area with a sofa bed, a work desk, and a walk-in glass shower—perfect for families or professionals.

Private rooms Sofia's B&B Hostal Boutique
Boutique hostel-style accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. The rate shown by Airbnb for your reservation is for 2 guests per room, i.e., guests will need to share beds and/or rooms. If you require a special room layout for your group, please contact the host first, as the rate may vary.

Corcho rooms #2 - king room with balconies
Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant an serviced guest rooms upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the building around are restored and the neighborhood is safe.

Spacious and lovely room meters from the sea - Ztz
Lovely spacious private room with a new brand bed, with great lightning and a workspace inside it. Shared bathroom. Shared kitchen with your private kitchenware and utensils needed to cook. Shared laundry room, with a washing machine

Your second home in Panama.
Our rooms are located in a prime area in the heart of the financial and banking sector of the city. We are two blocks away, two stations from the Metro transportation system. 15 minutes from some shopping malls.

The Corner Suite #110 | La Résidence Panamá
Contemporary comfort for the modern traveler. This 35–37 m² suite features a king-size bed, full kitchen, washer/dryer, Coffe machine, and A/C — designed with thoughtful touches to make you feel at home.

Pool side, Family suite, two bedroom one bath.
This trendy spot offers lots of charming details. Centrally located with many amenities, come enjoy our pool and spa. Dirección Crotón 818, Ancon, Panamá Wifi Red: cascadas Pass: 7636cascadas
Popular amenities for Panama City hotels
Family-friendly hotels

Double Room / Room two beds

Room with private bathroom

Rainforest Suite with Breakfast! 15 min from city

Bedroom with a private bathroom in downtown Panama

Private room with 1 double bed and bathroom

Room with private bathroom in downtown Panama

Bedroom and private bathroom in Panama City Center

Room with 3 single beds and a private bathroom
Hotels with a pool

Accommodation located near Vía España

Jr. Suite Rm #3 - Cerro Azul

Double Suite-Apartment Hotel Príncipe

Hacienda el Eden, the Cerro Azul Valley

Grand International Hotel

Private room 2 twin beds

Double Studio - Traveler Hostels

Excellent private room
Hotels with a patio

Harpy Eagle Room in Treehouse

Suite Room in the ORHO Hotel

Kakún Room 12, Cable TV, Refrigerator, Air Conditioning.

Eshel Panama Suites, Atlantic suite 04

Charming Studio w Two Double Beds

Private Twin | Shared Bathroom

cinta costera

Comfort and privacy, Casa Orquídea
Quick stats about hotels in Panama City

Total vacation rentals
Explore 130 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,092 GYD per night before taxes and fees

Verified guest reviews
Over 3,620 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Vacation rentals with a pool
30 properties feature pools

Rentals with dedicated workspaces
90 properties have a dedicated workspace

Wi-Fi availability
120 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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- Things to do Panama
- Nature and outdoors Panama
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