
Villa vacation rentals in Panama City
Find and book unique villas on Airbnb
Top-rated villa rentals in Panama City
Guests agree: these villas are highly rated for location, cleanliness, and more.

Spacious Mountain Getaway in Paradise Cloud Forest
Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

Surf Relax Play Pacific Ocean View Villa
White sand, surf-able waves, or just a comfortable chill vibe to enjoy the tropical weather of Panama. Playa Caracol is about an hour and 10 minutes drive from the city. This spacious, 2 bedroom, 2 bath villa with it's Pacific Ocean front location is the perfect place for you to enjoy an unforgettable family vacation. Walk out to the beach just steps from the villa, swim in the pool next to this villa or enjoy the resort pools and amenities. Or hike the nearby mountains with a local guide. PET

Ocean Pergola Villa (C10-PBB) 2 bed, 2 bath
Unique place steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views. Playa Caracol is located on the beach of Chame and is a newly developed area with expansion for the property and amenities. 1km of beach to offer you the best beach experience around.

5BR House in Panama City w/ Pool & King Beds
Enjoy a family or friends' getaway in this modern, newly remodeled house. This property boasts 5 bedrooms, 4.5 bathrooms, 10 beds, and can comfortably accommodate up to 15 guests. The house also features a private outdoor pool, where you can soak up the sun and cool off on hot days, all while being in a central location, just meters away from malls, supermarkets and night life. It's fully furnished with everything you could possibly need to ensure your stay is as comfortable as possible.

Villa La Vista-Panama's majestic mountain hideaway
Welcome to our Villa in Panama's Chagres National Park! We have installed a brand new spa heater in our pool (20Nov24) to enjoy breathtaking views of the surrounding mountain range. Take a dip in our stunning infinity pool, offering picturesque landscapes. Ultimate relaxation during sunset evenings in our inviting hot tub. A gym station you can stay fit. Jefferys Tamarin monkeys at our feeding station. Unwind in a hammock or enjoy a romantic poolside swing. Relax on the outdoor bar stools.

Breathtaking Views Mansion w/King Beds
Book your next thrilling Panama City vacation at our dreamy 11,500 sq. foot multi-story family mansion, superbly located on a hilltop high above the metropolis in this affluent neighborhood. Ideal for longer stays. Discover the vibrant buzz of Cinta Costera or explore the UNESCO world heritage sites at Casco Viejo – all under 5 km away from your doorstep. Enjoy a refreshing dip into the swimming pool and admire the sublime views of the Panama City Skyline from our unique roof terrace.

Beachfront 5BR Villa in Punta Chame ~Pool ~Rooftop
Relax in this spacious beachfront villa with a private pool, rooftop terrace, and palm-lined path straight to the beach. Perfect for families, groups, or special events — whether you’re sharing BBQ nights, watching sunsets on the rooftop, or simply soaking up the tropical atmosphere. Just 2 hours from Panama City and 5 mins to Punta Chame Beach! • Beachfront Villa with Direct Access • Private Pool + Palm Garden • Rooftop with 360° Sunset Views • Fast Wi-Fi & Dedicated Workspace

Villa with a swimming pool, soccer field, and stream
Quiet and spacious villa in Portobelo, Buenaventura. Enjoy a villa with a giant garden, river, soccer court, pool with waterfall and slide , 2 boyos, barbecue areas, terrace. 1 Master Bed with King Bed and Private Bathroom 2 bedrooms with 2 full beds. 1 bathroom in the room. 1 bathroom in the pool area and external shower. Living Room, Dining Room. Cable TV. Equipped kitchen. Hammocks. * The house is equipped with beds for 10 people, bring air mattresses with sheets.

Entire Villa with pool in front of beach!
Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Beach House with Pool/Gazebo in Punta Chame!
"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Villa Playa Caracol, 3 Bedrooms, Pet Friendly
¡Welcome to your perfect beach getaway! This charming ground-floor villa awaits you just 100 meters from the golden sand and refreshing waves of the sea. This home offers an ideal retreat for families and groups of friends looking to relax and enjoy the sun and sea breeze. Enjoy the pool right in front of the villa, where you'll also find a playground for everyone to enjoy. ¡Book now and experience a dreamy seaside vacation!

Villa Helena Studio 1 Apt Cerro Azul
One bedroom cottage with private kitchen and bathroom in a peaceful compound with shared pool. Internet and free parking available. Laundry facilities available for longer stays. Cook your own meals, or have me cook some authentic Caribbean dishes like curries, or use the restaurant available next door. Surrounded by nature and access to trails, waterfalls, rivers, swimming holes.
Popular amenities for Panama City villa rentals
Private villa rentals

Spacious house with a second floor!

SPACIOUS VILLA IN TABOGA - OCEAN VIEW

Ocean front Villa (C5-1C) 2 bed, 2 bath

Villa Las Palmas

Modern 4 bedroom Coronado Beach Villa

Villa Helena 2 Bedrooms Cerro Azul

Ocean View Villa Apt (C2-PBA) 2 bed, 2 bath

Cottage in remote and quiet area.
Luxury villa rentals

Beach Front House Surrounded by 2 Private Beaches

Beautiful Villa in Playa Escondida

Beautiful House in Panama w/ King Beds + Pool

La Semilla | Jungle Mansion | Panama City

House with an oceanfront pool

Casa Laguna - luxury beach front house with pool

Beach house in Punta Chame, Villa frente al mar

Saboga Beachfront Villa - Island Getaway for 11
Villa rentals with a pool

Pleasant Villa de Playa Villas Decameron Rio Hato

Cheerful 2-bedroom villa with shared pool

Gorgeous Pool View Two BR Beach Villa

Villa Santamaria en les blanc villas

"First Things First" - Your Beach Paradise awaits

In the Last Place in the World (6 guests)

Caribbean Beach House with Pool

Bahia Breeze 3 bdrm nature sanctuary with pool
Quick stats about villa rentals in Panama City

Total vacation rentals
Explore 10 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$16,732 GYD per night before taxes and fees

Verified guest reviews
Over 340 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 10 rentals that welcome pets

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
10 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Destinations to explore
- Cartagena Vacation rentals
- San Andrés Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Uvita Vacation rentals
- Boquete Vacation rentals
- Coveñas Vacation rentals
- Playa Blanca Vacation rentals
- Bahía Ballena Vacation rentals
- Ancón Vacation rentals
- Limón Vacation rentals
- Valle de Antón Vacation rentals
- David Vacation rentals
- Rentals with lake access Panama City
- Rentals with a home theater Panama City
- Rentals with a fire pit Panama City
- Rentals with a sauna Panama City
- Fitness-friendly rentals Panama City
- Rentals with a hot tub Panama City
- Family-friendly rentals Panama City
- Rentals with a fireplace Panama City
- Rentals with pools Panama City
- Condo rentals Panama City
- Bed and breakfasts Panama City
- Ski-in/ski-out rentals Panama City
- Rentals with an accessible height bed Panama City
- Cabin rentals Panama City
- Rentals with a patio Panama City
- Smoking-friendly rentals Panama City
- Guesthouse rentals Panama City
- Apartment rentals Panama City
- Beachfront rentals Panama City
- Boutique hotels Panama City
- House rentals Panama City
- Rentals with beach access Panama City
- Hotel rooms Panama City
- Rentals with an EV charger Panama City
- Private suite rentals Panama City
- Loft rentals Panama City
- Rentals with a washer and dryer Panama City
- Hostel rentals Panama City
- Townhouse rentals Panama City
- Rentals with outdoor seating Panama City
- Waterfront rentals Panama City
- Serviced apartment rentals Panama City
- Rentals with breakfast Panama City
- Pet-friendly rentals Panama City
- Villa rentals Panama
- Things to do Panama City
- Tours Panama City
- Sports activities Panama City
- Sightseeing Panama City
- Art and culture Panama City
- Food and drink Panama City
- Nature and outdoors Panama City
- Things to do Panama
- Sports activities Panama
- Food and drink Panama
- Tours Panama
- Sightseeing Panama
- Nature and outdoors Panama
- Art and culture Panama
- Entertainment Panama




