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Vacation rentals in Panama City

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Panama City

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Condo in Panamá
The Stylish Condo by AcoModo
La Cuadra is one of the most luxurious buildings in casco, with an amazing rooftop pool featuring a privileged stunning 360 view of the city skyline and pacific bay on one side, and the Panama Canal entry and Cerro Ancon on the other. The building has all the amenities for every client to experience a great stay in Casco Viejo. La Cuadra offers the best combination of amenities and central location, which is ideal to discover and enjoy the best of what Casco has to offer.
G$17,646 GYD per night
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Rental unit in Panamá
Modern apartment with gorgeous sea view
Modern and spacious apartment located on the coastal strip, with unique views of the sea and the Casco Antiguo of Panama. Large living-dining room with an integrated and fully equipped kitchen. Wake up with a view! The room also has spectacular views, it is spacious with a full bathroom, walk-in closet, and space to work. High-speed Internet, air conditioning, 65 inch TV, guest bathroom and laundry room. The building has a swimming pool and a gym on the top floor.
G$17,978 GYD per night
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Rental unit in El Cangrejo
The Comic Pop Studio by AcoModo
Enjoy a fabulous stay in this uniquely-styled studio at the best location in El Cangrejo. Located right across Parque Andres Bello in the heart of Via Argentina, this recently converted hotel is now the hottest accommodation in all of El Cangrejo. The location is second to none. Via Argentina has recently been redone and now has wide sidewalks, trees, lots of cafés, and the beautiful park in the center, right across from us.
G$10,061 GYD per night
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Stay near Panama City's top sights

Photo of Albrook Mall
Albrook Mall132 locals recommend
Photo of Multiplaza Panama
Multiplaza Panama147 locals recommend
Photo of Causeway Amador
Causeway Amador67 locals recommend
Photo of Miraflores Locks
Miraflores Locks216 locals recommend
Photo of AltaPlaza Mall
AltaPlaza Mall38 locals recommend
Photo of Trump International Hotel & Tower Panama
Trump International Hotel & Tower Panama10 locals recommend

Other great vacation rentals in Panama City

Rental unit in Panamá
Design and reformated duplex with pool A12
G$16,920 GYD per night
Condo in Marbella
★★★★★Luxury 1 bedroom apt with free parking
G$12,176 GYD per night
Condo in Panamá
The H2O Condo by AcoModo
G$19,520 GYD per night
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Condo in Panamá
The Abstract Art Condo By AcoModo
G$20,545 GYD per night
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Rental unit in Panamá
Completely renovated apartment with jacuzzi P8
G$14,955 GYD per night
Rental unit in Marbella
★★★★★Luxury 1 bedroom apt with free parking
G$12,176 GYD per night
Rental unit in Panamá
Apartment in Banking Area
G$13,597 GYD per night
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Rental unit in Marbella
Ocean Front Apartment Panama
G$18,189 GYD per night
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Rental unit in Panamá
w*| Modern 1BR With Rooftop Pool In Casco Antiguo
G$13,084 GYD per night
Rental unit in Panamá
w* | Artistic 1BR in Casco Viejo
G$14,232 GYD per night
Condo in Marbella
Av. Balboa, very high floor, luxury
G$15,924 GYD per night
Serviced apartment in Panamá
Stunning Sea View apt at city center
G$18,612 GYD per night
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Stays in Costa del Este

Rental unit in Costa del Este
Amazing Luxury Junior Penthouse Panoramic Views
G$33,931 GYD per night
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Private room in Panama City
Accommodation with Views in Costa del Este 1
G$5,922 GYD per night
Rental unit in Costa del Este
Beautiful apartment on the east coast
G$16,920 GYD per night
Rental unit in Panamá
Luxury Apartment a 8 minutos del aeropuerto
G$32,783 GYD per night

Stays in El Cangrejo

Rental unit in El Cangrejo
Full Loft - On Via Argentina El Cangrejo 250 Mbps
G$8,007 GYD per night
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Condo in El Cangrejo
R.1102 Nice executive studio in tourist area.
G$10,998 GYD per night
Rental unit in El Cangrejo
Beautiful loft in Via Argentina
G$8,249 GYD per night
Rental unit in El Cangrejo
Amazing private apartment on Via Argentina
G$10,455 GYD per night

Stays in Punta Paitilla

Condo in Marbella
★★★★★Luxury 1 bedroom apt free parking & balcony
G$12,479 GYD per night
Rental unit in Punta Pacifica
COZY APARTMENT IN PUNTA PACIFICA
G$12,479 GYD per night
Serviced apartment in Punta Pacifica
Hermoso apart en Ciudad de Panamá piso 2-C
G$13,735 GYD per night
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Rental unit in Punta Pacifica
Best Location in Panama
G$13,113 GYD per night
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