
Apartment vacation rentals in Panama City
Find and book unique apartments on Airbnb
Quick stats about apartment rentals in Panama City

Total vacation rentals
Explore 3,150 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,091 GYD per night before taxes and fees

Verified guest reviews
Over 97,220 verified reviews to help you choose

Family-friendly vacation rentals
1,010 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 1,180 rentals that welcome pets

Vacation rentals with a pool
2,170 properties feature pools

Rentals with dedicated workspaces
2,060 properties have a dedicated workspace

Wi-Fi availability
3,090 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
Top-rated apartment rentals in Panama City
Guests agree: these apartments are highly rated for location, cleanliness, and more.

k*| Breathtaking Oceanview 1BR in Ave Balboa
** POOL IS ON MAINTENANCE UNTIL SEP 15** Experience luxury in this oceanfront 1-bedroom apartment on Balboa Avenue with stunning views of the Pacific Ocean, Casco Viejo, and modern Panama City. Fully equipped for long stays with A/C, Water, TV, cable, and WiFi. Located in a unique building with amenities like Poin, a zipline between buildings, plus restaurants like Cielo, Osaka, and Patria. Walk to Cinta Costera and a subway station. Everything you need is right here—your perfect Panama getaway!

280 Degree Ocean View | 2 King Beds | 45 Day Min
Beautiful corner unit - 220 m2 / 2,400 ft2 apartment with a 280 degree unobstructed view of Panama City/Pacific Ocean overlooking the Panama Canal, Casco Viejo & Cinta Costera. Views & location don’t get better than this. V shape corner unit with 2 King Bed suites. The apartment is on the wonderful Avenida Balboa. There is a mini-mart on the corner and a brand new grocery store 3 blocks away. Blazing fast wifi at 500mgbs. This space is my personal home that I rent while traveling.

The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife

Ocean View Apt in Panama, Yoo&Arts
Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

5B • 5 Bedroom Apt • 4 Baths • Great for Groups
Apartment 5B is a modern 5-bedroom, 4-bath home designed for comfortable group stays, accommodating up to 10 guests with one king, three queens, and two single beds. It features a fully equipped kitchen, bright living area, fast WiFi, and spaces to relax or work. Centrally located in Panama City near restaurants, supermarkets, parks, and the waterfront. Guests enjoy full privacy, shared amenities including pool, gym, sauna, spa, and on-site support when needed.

Luxury apt in Panama City 2 Rooms 3 Baths
The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more

Apartment in the Causeway Amador
Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

The best view of the Old Town
Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

LUXURY APT/Ocean View & Rooftop
Modern luxury apartment on the Cinta Costera, ideal for executives, couples or families. Large bedroom with ocean view, private bathroom, kitchen and appliances. Elegant design with 24/7 security, gym, swimming pools, 4 restaurants, bar and Sky Lounge. Prime location near supermarkets and excellent cuisine in Panama City. PANAMA

Luxury Apartment | Walk to Restaurants & Shops
✔️ Superhost Verified Your stay will be in the best hands! 📍 Apartment in Yoo, Panama City, Panama. 🇵🇦 🏡 Clean, comfortable and safe space, great location 🧼 Equipped with supplies and cleaning supplies During your booking, your Airbnb has: 🌐 Wi-Fi. 📺 TV 🍳 Kitchen 🏊♀️Swimming pool ❄️ A/C
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Vive la Experiencia Wanders And Yoo en Panamá

Luxury Centric 2BR Apartment in Casco Viejo

Ocean View | Rooftop Pool | Luxury Stay

Unique Luxury 3-story Loft at the Yoo

Ocean View, Panama City

Luxury Oceanfront Resort 22nd Floor View, 200°

Old Town & Ocean View

Hotel-Style Room at The Hub, San Francisco
Private apartment rentals

Casa del Horno | A Piece of Panamanian History

Rooftop Pool • Centric • Metro 5 min • Parking

Elegant Renovated Yoo Penthouse 1 Bedroom

Luxury Designer Apt Casco Balcony + Rooftop Pool

Your Home Facing the Sea

Modern and Central · Nice Condo in the Heart of Pty

Beautiful Ocean View Studio on Ave Balboa

PH Yoo 44i – Ocean View Apartment
Apartment rentals with a hot tub

New Flat with Ocean + City Views

Tropical Paradise at Playa Bonita

PH The Gray | Balcony Views · Pool · Gym

Luxury 2BR Suite with Pool & Views

Luxurious apartment in Marbella

View and Comfort Apartment with Home Warmth

Ocean View | Infinity pool | Balbia Ave Apt

The Perfect Oceanview Getaway
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- Things to do Panama
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