
Apartment vacation rentals in Panama City
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Top-rated apartment rentals in Panama City
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Modern apartment in the heart of Obarrio
This apartment stands out for its privileged location in Obarrio, with a modern and cozy design. Located on the 14th floor, it offers a spectacular view, its decoration in neutral tones conveys serenity. The convenience of having two bathrooms makes it unique. Ideal for travelers looking for tranquility and functionality. Located within walking distance of 50th Street and the iconic El Tornillo building. You're surrounded by casinos, hotels, and restaurants. Safe area for walking and enjoying the city.

Casco Viejo 360° View Old Tower Penthouse
Located in one of the oldest buildings in Panama and set over 3 stories with unrivaled panoramic views over the historical Casco Viejo, the skyline of Panama City and views of the causeway, our gorgeous penthouse is the ideal space to take in the local sights, sounds, art, culture, socialize with your friends and family, or simply relax in a cozy love nest! Top speed wifi, excellent location, and fully equipped with all the home comforts, the penthouse is the perfect spot to explore Panama.

Cozy 2 Bedroom w/ Splash Pool
Our place is a 3-story apartment located on the quiet side of Casco Viejo. It has a very private feel to it, which allows for an incredible afternoon of sunbathing or bbqing on our private rooftop. The splash pool allows for a refresh and fits 2 people at a time. This place has so much character from with original exposed stone walls, to the sweeping view of the Arto Chato ruins. It also has a great work space, all the necessities to stay in and cook, watch a movie, etc.

Cozy Apartment with Free Parking Coworking
Welcome to our charming apartment in the heart of Panama City! Perfect for digital nomads who take their office with them. At LIVING 73 you will enjoy a wide range of amenities, such as swimming pool, a coworking space and gym. Located in the San Francisco area, it's the perfect starting point for exploring the city. You will find within a 5 minute walk a wide range of restaurants, supermarkets and the Multiplaza Mall, the largest and most varied in the city.

Escape to the Heart of Casco with a Private Balcony
Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Jacuzzi & Private Rooftop recently refurbished D11
Welcome to Casa Diez, the most romantic spot in the Old Town! Enjoy a unique experience in this room for two, featuring an exclusive outdoor Jacuzzi overlooking the starry sky. Relax in a comfortable queen-size bed, with a private bathroom, air conditioning, Smart TV, and Wi-Fi. You'll also have access to a beautiful shared pool and laundry center, exclusively for our guests. Enjoy an unforgettable stay in a cozy, intimate, and fully equipped setting.

Modern and Central · Nice Condo in the Heart of Pty
¡Modern 50 m2 apartment located on Calle 50, in the heart of Panama City!. With access to the best in art, culture, business, finance, sports, shopping, food, and nightlife. * The space has a room with a queen size bed, full bathroom, smart TV and desk with monitor (HDMI cable) for those traveling without disconnecting from work. * The living room has a comfortable sofa bed, full bathroom, dining room and kitchen equipped for kitchen lovers!.

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Elegant apartment with a view & the warmth of home
This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.

Ocre Studio | By Paradox
PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.
Popular amenities for Panama City apartment rentals
Weekly apartment rentals

Beautiful apartment in Casco Viejo ST. George D

Suite Luxury 30th View , Cinta Costera Panama

Lovely & Cozy central apartment in Casco Viejo

PH Yoo 44i – Apartment with Ocean View

Unit 62A at the YOO Balboa ave. Sea View

Large Apartment in La Cuadra - Casco | By Alura

La Maison de Dave - Lovely 2- Bedroom rental apt.

Desing House Obarrio by God Housing
Private apartment rentals

w* | Whimsical 1BR in Plaza Catedral

A cozy Casco Viejo apartment

Centrico condo frente Hotel Sortis, Downtown

Elegant Apt in Costa del Este. Premium Amenities

In the Heart of Panama Pacifico

Historic Albrook Duplex near Albrook Mall

YOO Panama · Luxury signature ocean view. 57th fl

Modern skyscraper, free breakfast, pool, gym
Apartment rentals with a hot tub

Apartamento entre oceano y selva

Luxury Apartment in Panama | 2BR + Views + Pool

Luxury Beachfront Apartment Near Panama City

Modern Furnished Studio with Ocean Views in Panama

Spacious Oceanfront Apartment

Luxurious Apartment Oceanfront View

Tropical Paradise at Playa Bonita

Grand Panoramic View Casa Bonita 2 BR 2.5 Bath
Quick stats about apartment rentals in Panama City

Total vacation rentals
Explore 2,770 vacation rentals in Panama City

Nightly prices starting at
Panama City vacation rentals start at G$2,093 GYD per night before taxes and fees

Verified guest reviews
Over 71,040 verified reviews to help you choose

Family-friendly vacation rentals
850 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 990 rentals that welcome pets

Vacation rentals with a pool
1,730 properties feature pools

Rentals with dedicated workspaces
1,720 properties have a dedicated workspace

Wi-Fi availability
2,640 of Panama City vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)
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- Things to do Panama
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