
Apartment vacation rentals in Panama City
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Top-rated apartment rentals in Panama City
Guests agree: these apartments are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama City apartment rentals
Apartment rentals with air conditioning

Apartamento Av. Balboa, Yoo&Arts
Place is in a great location . Too has lots of amenities .

Spacious Oceanfront Apartment
Accommodation matches the photo. Very easy access. And pleasant setting. Very responsive and attentive host.

Unit 62A at the YOO Balboa ave. Sea View
Very comfortable and well maintained. Great communication with hosts and corrected minor issue immediately. Thanks!

19L Breathtaking Oceanview Playa Bonita Resort
Nice place and views and there was a local store for any food needs. The place was 30-40 minutes from the downtown of Panama and traffic was terrible getting to Panama. But the condo made up for the headache of the traffic we looked forward to coming back to our temporary home. Thanks for allowing my family and I to stay at your villa.

OceanView Balcony •Remote Working• Near Multiplaza
It's a new apartment. Have a good view. 100% recommend

The Spot Panama - Comfy, great view & much more
jerrick was a wonderful host. very responsive very helpful and friendly. the apartment was exactly as described and had all the amenities listed. Linens and toiletries were provided. The apartment has a beautiful view of the city. There is a supermarket and a few restaurants within walking distance. We had a wonderful stay at this apartment

Luxury apartment in downtown Panama, banking area
Friendly, responsive host. Great location - close to food & entertainment. Building security was super helpful & accommodating.

Quiet apartment in the heart of Casco with patio
Beautiful place to stay, near the historic places, restaurants and bars of the Old City.
Apartment rentals with a hot tub

3 bedroom penthouse with spectacular views!
Martin’s penthouse is our home away from home in Panama! We love the views, the cleanliness of the penthouse and the safety provided to the guests. We will continue to book this penthouse anytime that we visit Panama! We can’t wait to go back!

Panama Luxury | Condo Suite 2BR
This apartment in Costa del Este is absolutely amazing! The view is stunning — you can see the skyline and ocean, and it truly feels like you’re in Miami. The apartment was super clean, modern, and cozy, with everything I needed to feel at home. I especially appreciated how Erick was always available and helpful during my stay. His support made everything even smoother. The location is perfect — safe, central, and close to shops, restaurants, and more. I recommend this place 100% and would definitely book again! Este apartamento en Costa del Este es simplemente increíble. ¡La vista es espectacular! Se ve el skyline y el mar, y de verdad se siente como estar en Miami. El apartamento estaba impecable, moderno y muy cómodo, con todo lo necesario para sentirse como en casa. Además, Erick estuvo siempre disponible para ayudarme en lo que necesitara, lo cual hizo la experiencia aún mejor. La ubicación es perfecta: segura, céntrica y cerca de todo. Recomiendo este lugar al 100% y sin duda v

Beautiful colonial condo with a hot tub and balcony
It was a pleasure to be a guest at Oddy. Communication was always very fast and hassle-free. The apartment is as shown in the photos and in the description. I was very satisfied with everything and recovered well. The location is in Casco Viejo and therefore ideally located for various restaurants and bars. Would come back in a heartbeat!

Suite Luxury 30th View , Cinta Costera Panama
The place was great and exactly as described. Very comfortable as well. Exceptional host. Communication could not have been better. Victor went above and beyond what was required. Thank you!

Luxurious Apartment Oceanfront View
My husband and I stayed at José's place for a quick birthday trip and we loved it! Firstly, José is very responsive and is a great communicator. We felt right at home and most importantly we felt very safe. The apartment itself is gorgeous! Looks exactly like the pictures and that view is everything. The bed was comfortable and the shower was HOT. The building itself is very nice with amazing amenities inside like restaurants, a place for kids, spa, gym, and rooftop pool area. The building is also within walking distance to a lot of great restaurants and things to do. I would stay at José's place again in a heartbeat!

Tropical Paradise at Playa Bonita
Lovely views, excellent amenities and very hospital people. Would definitely stay again.

Apartment, Panama City.
Everything as described, super easy check in and the building has 3 beautiful restaurants and a food market attached, great 1 night stay.

Great view of the bay.
We had a fabulous week at Leidy's apartment. She was very flexible on our needs and responded very quickly. Apartment had great ocean views, easy access to stores and restaurants and we got around Panama City easily using Uber. The security in the lobby were also very friendly. Thank you Leidy for a great stay.
Weekly apartment rentals

Apartment 2bed,2bath and large terrace in the city
Great place will recommend

Charming Oceanfront Apartment
We really enjoyed the property. It was very roomy and more spacious than the pictures show. While the property is located in the tourist area, we were never bothered with any outside disturbances or noise. This was our first visit to Panama and first time in an AirBnb; we are so glad we chose this property and were really pleased with everything. We have absolutely nothing but great things to say about the property and our experience.

Ocean view apartment! On the coastal belt
Easy to find. Great view

Centrally located, elegant and minimalist
The flat was exactly as described. It was very cosy with hot water and in a great area. Jesús was extremely responsive and helpful. It was a great place to stay for a city break.

Penthouse Panoramic View with Luxury Amenities
Would recommend for a vacation, clean and the host was very helpful with our check in. Comfortable and safe feeling location, there is also a food hub right across the street so that’s a plus.

Apto 4 min from Tocumen Airport | 24-hr check-in
This condo was very close to the airport. About a 5 min drive. New condo bldg so everything was very clean. The condo had everything I needed and then some. The host was very helpful. I would stay again for sure!

Classy, New and Sea View Condo • Best Location!
Excellent stay. Conveniently located, good food options nearby, warm staff, nice gym, amazing pool. Highly communicative host. Probably the next place I stayed in Panama City!!

Charming flat with roof top pool in Casco Viejo
I am a world traveler. I have been to so many places and different countries, I must have been in about 15 plus different places in Panama alone. I am so spoiled now and the reasons for this is my stay at La Cuadra it was just Pefect!!! Very comfortable, lovely, classy and the furnishungs... Beautiful! Everyone working in the building was so sweet and helpful. The host Stefanie Wowa, Amazing... above and beyond!!! You cannot not find a better place to stay. I don't care how much money you spend. I've done it all. This is the very best place. Thank you all for my perfect stay.
Quick stats about apartment rentals in Panama City
Total rentals
2.6K properties
Nightly prices starting at
G$2,092 GYD before taxes and fees
Total number of reviews
62K reviews
Family-friendly rentals
860 properties are a good fit for families
Pet-friendly rentals
870 properties allow pets
Rentals with a pool
1.6K properties have a pool
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