Apartment vacation rentals in Panama City

New Flat with Ocean + City Views

Brand new apartment in a high rise in the middle of downtown Panama. Very centrally located. Two fully furnished rooms and fully equiped kitchen. Gorgeous views of the city and Pacific ocean. Guests will have access to all the building's amenities such as a pool, gym, coworking space and game room. 15 minutes walking distance to Casco Viejo. 5 minute walking distance to Mercado de Mariscos, Cinta Costera and to the 5 de Mayo Metro Station. Airport Pickup and Dropoff Services Also Available.

Family · Value · Wifi

Ocean View Apt in Panama, Yoo&Arts

Iconic luxury at Yoo&Arts Panama. This spectacular 130m² (1,400 sq ft) apartment offers sophisticated design and a breathtaking panoramic view of the Pacific Ocean. Enjoy breakfast on the balcony with an exceptional breeze, watch the sunrise from your bedroom, or work in an inspiring environment. Located on Avenida Balboa, the city's most exclusive area, you’ll have direct access to fine dining inside the building, premium supermarkets, and shopping malls nearby.

Location · Value · Sleep quality

5B • 5 Bedroom Apt • 4 Baths • Great for Groups

Apartment 5B is a modern 5-bedroom, 4-bath home designed for comfortable group stays, accommodating up to 10 guests with one king, three queens, and two single beds. It features a fully equipped kitchen, bright living area, fast WiFi, and spaces to relax or work. Centrally located in Panama City near restaurants, supermarkets, parks, and the waterfront. Guests enjoy full privacy, shared amenities including pool, gym, sauna, spa, and on-site support when needed.

Location · Family · Laundry

Luxury apt in Panama City 2 Rooms 3 Baths

The Wanders by yoo building is located in the heart of the city. It is an extraordinary project where every corner has a story to tell. 24/7 reception, many recreation areas, hydration station. Outside the lobby, there is the Cafetería cafe con teclas and a Popino Carnes restaurant. In the social area, bar service in the pools, children's park, games room with screens on the ceiling bathrooms, function room, kitchen for events, fully equipped gym and more

Value · Location · Sleep quality

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

Family · Value · Wifi

Apartment in the Causeway Amador

Forget your worries in this spacious and serene space. Where you can enjoy the views of the Panama Canal and see the boats that pass through it, a space full of amenities with a perfect location, you can walk through the streets of the Causeway, visit the Biodiversity Museum, restaurants of various specialties, amusement park, bike rides etc, everything comes together to make this vacation an unforgettable experience for your whole family

Family · Location · Checkout

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Value · Family · Condition

The best view of the Old Town

Welcome to this charming accommodation located in the heart of Casco Viejo, on the third floor facing one of the most iconic squares in Panama, Plaza Catedral! Thanks to its privileged location, you will enjoy a unique view of the square and the imposing Cathedral Church. Right in this lively square, you will have at your disposal a wide variety of restaurants and shops where you can buy souvenirs of this wonderful trip.

Family · Location · Indoor spaces

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Location · Family · Cleanliness

Luxury Apartment | Walk to Restaurants & Shops

✔️ Superhost | Yoo Panama 🇵🇦 🏙️ Enjoy an exclusive apartment designed by Philippe Starck, with spectacular views of the bay and a prime location on Av. Balboa. 🌊 ✨ It has Wi-Fi, Smart TV, equipped kitchen, A/C, queen-size bed and private bathroom. 🏊‍♀️ Access to resort-style pool, gym, spa, restaurant, parking, and 24/7 security. 🆔 Only pre-registered guests with ID may enter.

Location · View · Laundry

Ocean View, Panama City

Stunning views of the ocean and the Old Town, with direct access to the Poin Panamá resort, as well as a variety of dining options and bars, for an unparalleled vacation experience. ⚠️ Important notice: The building's pool and gym will be temporarily closed for maintenance from August 24 to September 15, 2026. Thank you for your understanding.

Location · Laundry · Indoor spaces

LUXURY APT/Ocean View & Rooftop

Modern luxury apartment on the Cinta Costera, ideal for executives, couples or families. Large bedroom with ocean view, private bathroom, kitchen and appliances. Elegant design with 24/7 security, gym, swimming pools, 4 restaurants, bar and Sky Lounge. Prime location near supermarkets and excellent cuisine in Panama City. PANAMA

Location · Family · Air conditioning