Guesthouse vacation rentals in Gainesville

An RV is parked on a concrete pad in a green area, featuring a retractable awning for shade. Nearby, simple steps lead to the entrance. The camper's exterior is a combination of silver and black, with a door and a small propane tank visible.

4.92 out of 5 average rating, 134 reviews

Cozy Camper Stay

Experience camper life in a quiet neighborhood 20 minutes from the heart of Gainesville! Staying in a camper is a unique adventure! Before reserving, please note: ***NO SMOKING*** Shower and bunk beds CANNOT accommodate folks taller than 5'8". No TV or Wifi. Toilet is connected to a holding tank rather than traditional plumbing. If the valve is held open longer than necessary when flushing, odors from the tank can escape into the RV. There are steps getting in and out of the camper. Take care.

The exterior of a charming guest house is illuminated by soft outdoor lights, highlighting its blue siding and white trim. A covered porch extends from the entrance, while potted plants line the pathway, set against a backdrop of trees and an open lawn.

4.88 out of 5 average rating, 228 reviews

Sunflower Acres Cottage

Cute, cozy, freshly remodeled, private guest house on a beautiful 5 acre farm. Enjoy your own backyard herb garden with privacy fence, picnic table and fire pit. New kitchen with gas stove, microwave, toaster oven, coffee-maker, and dining area perfect for enjoying meals. The bedroom is equipped with a smart TV, queen bed, & extra blankets. This country getaway is near the University of Florida (12 miles), Blue Springs (21 miles) Ginnie Springs (24 miles), and historic High Springs (15 miles).

An inviting living area is showcased with a dark leather sectional sofa and a light wooden coffee table placed centrally. A flat-screen television is positioned above an understated media unit. Natural light filters through the window, enhancing the neutral tones of the carpeted floor.

4.92 out of 5 average rating, 106 reviews

Studio in the “Swamp”

400 square foot space located minutes from University Florida Campus,and Downtown Gainesville. Easy access to/from I-75 on Southside of Town via Williston Rd. Minutes from Archer Road and Celebration Pointe. This Bonus Room above the garage is completely separate from the main house. Access is provided through the garage with ample parking available. Great location for attending Gator Sports: Football, Basketball, baseball, etc. Enjoy the wildlife at Sweetwater Wetlands across the street!

The exterior of the loft showcases a charming A-frame structure, accentuated by wooden beams and a warm glow from the illuminated windows. Soft string lights create an inviting atmosphere around the pathway, which is framed by lush greenery and leads to a shared firepit.

4.95 out of 5 average rating, 262 reviews

Walk to UF! Historic King Bed Loft w/ Private Deck

If you are visiting Gainesville, look no further than Camellia Loft. This historic gem was built in 1924 and has been freshly renovated to bring it into the modern era. Enjoy the birdsong and majestic trees from your private deck overlooking the backyard—or relax inside as light streams through the loft's massive skylights. Only 0.5 miles to UF campus and exactly 1 mile to the stadium, you can easily walk to campus or games. Unwind by the shared fire pit or enjoy cooking on the grill

A well-appointed sleeping area features a spacious bed dressed in light gray bedding, flanked by two bedside tables with stylish lamps. Colorful wall art complements the space, while natural light streams through several textured windows, enhancing the tranquil ambiance.

4.97 out of 5 average rating, 584 reviews

Renovated Private Studio - Walking Distance to UF

NEWLY RENOVATED - Enjoy your Gainesville stay in this mid-century modern studio 0.5 miles from UF and 2 miles from UF and HCA hospitals. No detail was overlooked in this beautifully designed detached guest house with an abundance of natural light, upscale finishes, and endless amenities - kitchenette, mini fridge/freezer, smart TV, and more! This conveniently located private and quiet space in the heart of Gainesville is perfect for anyone visiting for just one night or a few weeks.

4.98 out of 5 average rating, 131 reviews

A rustic cabin is nestled among trees, featuring a spacious front porch with a wooden railing. Two kayaks, one red and one orange, rest on the ground nearby. The structure has multiple windows allowing natural light inside, complemented by a sloped metal roof.

Guesthouse in Fort White

Adorable cozy cabin near North Florida Springs

Keep it simple at this peaceful cabin….Centrally-located to Itchetucknee Springs, Ginny Springs, Poe Springs, Blue Springs, Santa Fe River, Suwannee River. This area is popular for diving , snorkeling, boating, fishing, kayaking, tubing and hiking or just relaxing with nature. Full kitchen, living room and separate bedroom with a comfortable queen bed and walk-in closet. A large bathroom with walk-in shower. Wi-fi throughout. 42” smart tv in living room, 32” smart tv in bedroom.

5 out of 5 average rating, 118 reviews

The kitchen features modern appliances, including a stainless steel refrigerator and oven. White cabinets complement the dark countertops, and a small dining table with four chairs is positioned near a window that allows natural light to fill the space.

Guesthouse in Duckpond

Beautiful 1-Bedroom Guest House Historic District

Brand New One-Bedroom Guest House in the Historic District near Downtown Gainesville. This stylish, centrally-located rental is located in the backyard of our property and was designed by an architect on the historic board in the city of Gainesville, along with our son, who is also an architect. There is a fully-equipped kitchen, full bathroom and a bedroom with a queen-size bed. The ceilings are 9-feet high, giving a feeling of extra space in this 420-sq. foot guest house.

4.96 out of 5 average rating, 187 reviews

The spacious living area features a comfortable sectional sofa in shades of gray, with decorative pillows for added comfort. Large windows allow natural light to stream in, with views of the surrounding greenery. A coffee table sits in front of the sofa, complemented by a dining table visible in the background.

Guesthouse in Archer

Your own private space of peace and quiet.

Keep it simple at this peaceful and centrally-located place. While being only 15 miles from the nightlife of downtown Gainesville, this is country living at it best. With no street lights the stars are bright and easily counted. The mornings are bright and full of the music of bird songs. The cute 2 bedroom apartment (one double bed, two single beds) is on the SECOND FLOOR. It is easy to get lost in the whisper of the trees. This is a place to rest your soul and unwind.

5 out of 5 average rating, 114 reviews

A modern guest house is showcased, featuring a light green exterior and a wooden deck with Adirondack chairs. Lush greenery surrounds the space, with trees providing shade and a small garden area visible in front. Natural light is welcomed through large windows.

Guesthouse in Oakview

Azalea Guesthouse - Close to UF and downtown

Lots of character in this brand-new guest house located in the heart of town on a quiet canopied neighborhood and walking distance to UF, stores and coffee shops. Wake up in the morning to birds singing in the lush backyard, enjoy your coffee on the deck, or an evening stroll around the quiet neighborhood. Just a few blocks from UF and downtown, this retreat is perfect for your next Gator game weekend or to enjoy the nature, art and culture Gainesville has to offer!

Guesthouse in Porters Community

A well-lit studio bedroom features a spacious bed covered with a light blue blanket. Two windows provide natural light, while a mounted television and air conditioning unit are positioned on the wall opposite the bed. Neutral colors create a calming environment.

4.91 out of 5 average rating, 235 reviews

Downtown Studio - 1/2 Mile from UF Campus

This Downtown Studio has just been remodeled and is located on a very private and tranquil property situated in the heart of Gainesville. Half a mile from UF Campus and 1.5 miles to Shands Hospital / VA. Within a few blocks are many of Gainesville's favorite restaurants, coffee shops, museums and nightlife. Facilities available are: Amazon Fire TV with access to Netflix and Prime TV; high speed internet; induction cook-top, coffee press, microwave and a fridge.

4.88 out of 5 average rating, 1,102 reviews

A two-story black wooden structure is depicted, featuring a spacious balcony adorned with seasonal decorations. Stairs lead to the upper level, and a covered area with parking is visible below. Surrounding greenery includes tall trees, enhancing the natural setting.

Guesthouse in Lake City

Studio loft/ kitchenette/porch/bath

3 Miles from I75 exit 414 .studio apartment w/ porch over barn. Fire pit with wood available. Grill. Hammock swings under oaks. Stalls available. Close to riding/hiking trails in O'leno State Park. Close to springs for tubing/kayak/canoe. Ichetucknee Spring State Park, Ginny Springs, ++. Also 15 minutes from Santa Fe River and paddling/kayak/canoe rentals . Diving excursions available in High Springs. Quiet setting w/ pastures and grand daddy oaks.

4.93 out of 5 average rating, 184 reviews

A two-story, yellow house is set among lush greenery, showcasing a spacious driveway covered with pine straw. A car is parked under a shelter attached to the structure, and the surroundings exhibit mature trees and natural landscaping.

Guesthouse in Micanopy

Private bed and bath above detached garage.

Close to Paynes Prairie Preserve State Park, Micanopy's unique downtown and a short easy drive to UF campus. North of Micanopy on Highway 441 across from Lake Wauberg. A common private driveway from the highway leads up to our two story home and two story detached garage. Uber not a good option. Good for couples, solo adventurers, and business travelers; and great for Gator friends and fans. Smoke free and no pets please.

Popular amenities for Gainesville guesthouse rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guest house rentals

4.88 out of 5 average rating, 176 reviews

A shaded seating area is featured in front of a charming blue cabin. A small round table is accompanied by two lightweight chairs, topped with a decorative umbrella. Surrounding greenery enhances the peaceful outdoor setting.

Guesthouse in Trenton

Springs capital of the world

A comfortable living area is presented with a sectional sofa adorned with colorful cushions. A gently patterned area rug anchors the space, complemented by a sleek coffee table. Natural light streams through multiple windows, enhancing the inviting ambiance.

5 out of 5 average rating, 11 reviews

Cozy Casa in the Heart of Gainesville - 12 guests!

Private room in Gainesville

New place to stay

Guesthouse w bath&kitchenette. Walk to UF

Guesthouse in Melrose

Bass Lake Oasis

A charming two-story guest house is set against a backdrop of lush greenery. The exterior features bold blue siding and large windows, while a stone pathway leads to the entrance. Two blue chairs are placed on gravel, inviting relaxation in the surrounding nature.

Guesthouse in Alachua

The Gratitude Guest House

Quiet King Bed Cottage w/ Yard+Bike in Central GNV

4.92 out of 5 average rating, 37 reviews

The exterior features a charming yellow facade with textured shingles and large windows. A turquoise door creates a welcoming entrance, framed by greenery and potted plants. The walkway, lined with pavers, leads to the door, offering easy access and an inviting atmosphere.

Private room in Alachua

King room at Pareners Branch Creek Guesthouse

4.97 out of 5 average rating, 30 reviews

A spacious living area is displayed, featuring a light-colored sofa adorned with orange and patterned pillows. A wooden coffee table is centered in front of the sofa, with a small plant adding a touch of greenery. A large window offers views of the outside landscape, and a sleek ceiling fan hangs above.

Guesthouse in Alachua

Sweetwater Studio, on 5 beautiful acres

Guest house rentals with a patio

5 out of 5 average rating, 16 reviews

Guesthouse in Reddick

Papy's Place - Horse Farm Retreat

A spacious studio layout features a large bed with a dark headboard, accompanied by two bedside lamps. A cozy brown sofa sits in the foreground. A decorative curtain softly filters light, and a large plant adds a touch of greenery, enhancing the inviting ambiance.

4.98 out of 5 average rating, 94 reviews

Millhopper Modern near UF&Shands

4.98 out of 5 average rating, 48 reviews

The exterior of the guesthouse features a welcoming porch with wooden steps leading to a covered entrance. Inside, an open-concept kitchen and living area are highlighted by modern appliances and a cozy couch. In the bottom images, a goat with a kid and a horse are visible, set against a pasture backdrop.

Guesthouse in Williston

Hilltop Retreat

Guesthouse in High Springs

A private pool is surrounded by a stone patio, with a bright blue inflatable float resting on the water's surface. Lush greenery and a hammock can be seen in the background, providing a serene outdoor environment.

4.75 out of 5 average rating, 52 reviews

Private Detached Pool House With Kitchenette

A kitchenette is situated adjacent to a dining area, featuring modern appliances, including a mini fridge and microwave. A round dining table is surrounded by light-colored chairs. Natural light filters through a nearby window with bamboo shades, revealing a glimpse of lush greenery outside.

5 out of 5 average rating, 21 reviews

The Perch at Misty Hollow

The living area features a light-filled, open layout with a cozy seating arrangement that includes a gray sofa and accent cushions. A kitchenette is visible in the background, equipped with essential appliances. Light filters through the blinds, creating a warm ambiance across the space.

4.81 out of 5 average rating, 63 reviews

The house of smiles.

4.99 out of 5 average rating, 132 reviews

A serene sunset is captured over a sprawling green landscape, featuring distant trees and a winding driveway that leads into the horizon. Fencing outlines the fields, with soft clouds painted in hues of orange and pink across the evening sky.

Guesthouse in Reddick

Ocala - Reddick Equestrian Studio Apartment.

A two-story guest house is surrounded by vibrant greenery, featuring a staircase leading to a welcoming entrance. Natural light highlights the exterior, which includes large windows and a simple design, offering a sense of tranquility and connection to nature.

5 out of 5 average rating, 102 reviews

"Nest" in the Guest House up in the Trees near UF

Guest house rentals with a washer and dryer

A charming light blue exterior of the suite is framed by well-maintained greenery. A private entrance is visible, along with a small patio area that leads to a cozy seating option in the background.

Guesthouse in High Springs

4.72 out of 5 average rating, 29 reviews

Mother in Law suite/Apartment @ Staycation

4.98 out of 5 average rating, 93 reviews

A table is adorned with a vibrant arrangement of yellow flowers surrounding three white candles. In the background, a wooden Adirondack chair is positioned on a patio, shaded by a roof and framed by trees and open outdoor space.

Guesthouse in Fort White

Horning’s Guest House -room for 15

A spacious bedroom features a wooden bed with a plush white coverlet and decorative pillows. Soft lighting is provided by two bedside lamps and a standing lamp, illuminating the warm wood tones. A small side table and a chair with greenery accentuate the space.

4.87 out of 5 average rating, 62 reviews

Cedar Guesthouse | Near UF, Stadium, Bat House

5 out of 5 average rating, 91 reviews

An airy and open layout showcases a cozy sleeping area with a spacious bed adorned in soft linens. Nearby, a small dining table and chairs are visible. A comfortable seating area includes an armchair and a small couch, with natural light filtering through multiple windows.

Guesthouse in Duckpond

Garden Cottage Sanctuary

4.91 out of 5 average rating, 45 reviews

A cozy bedroom features a spacious bed with crisp white linens and a soft beige throw. An air conditioning unit is mounted above, while a bedside lamp provides gentle lighting. A door leads to a full bathroom, visible in the background.

Guesthouse in Sugarfoot

Palm N' Pillow • Guesthouse by UF, HCA-FL & Shands

5 out of 5 average rating, 3 reviews

Quiet+Safe Guesthouse w/Yard+Parking, Near UF

5 out of 5 average rating, 19 reviews

The cottage exterior features a well-maintained lawn with vibrant green grass and a palm tree nearby. A small deck is highlighted with red rocking chairs, set against a backdrop of a sunset sky. The property is bordered by a wooden fence, providing a country setting.

Guesthouse in Williston

New cottage on horse farm- 1 min from Devil's Den

The open-concept living room features a comfortable gray sofa and matching loveseat, positioned thoughtfully around a white coffee table. Subtle light filters through the window, illuminating a decorative wall piece. A soft area rug underfoot adds texture to the space.