Guesthouse vacation rentals in Gainesville

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Top-rated guesthouse rentals in Gainesville

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Guesthouse in Gainesville

4.94 out of 5 average rating, 114 reviews

By I-75 Clean Private Safe! Laundry & Kitchenette!

Welcome to Falcon's Nest! Deluxe Peaceful Suite near 1-75. Whether you're just stopping for a night or here to explore our glorious crystal clear springs and enchanting hiking & biking trails, your sanctuary awaits! Lush 1-acre lot w/ Private Entrance & Patio & Secure Parking, the Suite features a Cozy Bedroom, a Sitting/Dining Room w/ French Doors to your Patio, a Clean Private Bathroom w/ Luxurious Shower, Full Kitchenette w/ Laundry, Widescreen TV, Fast Wi-Fi, and more Unique Amenities! :-D

Aug 11 – 18

G$13,617 GYD per night

Guest favorite

Guesthouse in Gainesville

4.86 out of 5 average rating, 179 reviews

Sunflower Acres Cottage

Cute, cozy, freshly remodeled, private guest house on a beautiful 5 acre farm. Enjoy your own backyard herb garden with privacy fence, picnic table and fire pit. New kitchen with gas stove, microwave, toaster oven, coffee-maker, and dining area perfect for enjoying meals. The bedroom is equipped with a smart TV, queen bed, & extra blankets. This country getaway is near the University of Florida (12 miles), Blue Springs (21 miles) Ginnie Springs (24 miles), and historic High Springs (15 miles).

Oct 13 – 20

G$18,314 GYD per night

Guest favorite

Guesthouse in Gainesville

4.98 out of 5 average rating, 640 reviews

Unique Container "Caja Verde" 1 Mile UF & Downtown

Our home is less than a mile to UFHealth at Shands and the Malcom Randall Veterans Medical Center. We are a mile to the University of Florida campus. Amazingly, also a short bike ride (1-2 miles) to Downtown Gainesville. Close to Depot Park, art studios, restaurants, music venues, and theater. Nature parks close too. The bonus is we live on 2 acres, tucked back in a quiet neighborhood. Our pool is deep & cool; we have bikes to borrow. The container is perfect for a solo traveler, or a couple.

Jul 3 – 10

G$18,406 GYD per night

Guest favorite

Guesthouse in Gainesville

4.98 out of 5 average rating, 158 reviews

Walk to UF! Historic King Bed Loft w/ Private Deck

If you are visiting Gainesville, look no further than Camellia Loft. This historic gem was built in 1924 and has been freshly renovated to bring it into the modern era. Enjoy the birdsong and majestic trees from your private deck overlooking the backyard—or relax inside as light streams through the loft's massive skylights. Only 0.5 miles to UF campus and exactly 1 mile to the stadium, you can easily walk to campus or games. Unwind by the shared fire pit or enjoy cooking on the grill

Dec 22 – 29

G$28,414 GYD per night

Guest favorite

Guesthouse in Gainesville

4.9 out of 5 average rating, 134 reviews

Private cottage convenient to downtown and UF.

Quiet, private studio cottage with screened in porch that look out to the spacious yard and gardens. Off street parking, walking distance to downtown, Santa Fe downtown campus, Dragon Rises, Five Elements, and 2.5+ miles to UF/Shands. Easy accèss to the airport, libraries, museums, local parks, swimming, and biking trails. Kayaking, cave diving, and other activities just a few miles away. Enjoy your stay with a comfortable queen size bed, internet, coffee, and a modest kitchen.

Aug 4 – 11

G$17,600 GYD per night

Guest favorite

Guesthouse in Gainesville

4.9 out of 5 average rating, 365 reviews

B&B's Downtown Steampunk

Grab a slice of Wow in this turn-of-the century Steampunk design carriage house in Gainesville’s picturesque Bed and Breakfast District. It’s a stone’s throw from downtown’s fine dining, coffeehouses, craft beer breweries, and the famous Bo Diddly Square’s music venue. Check out plays and movies the historic Hippodrome . . . all this is within a walking radius of a few short blocks. Enjoy your restful retreat’s unique style that combines historical elements with science fiction.

Jul 23 – 30

G$18,808 GYD per night

Superhost

Guesthouse in Lake City

4.88 out of 5 average rating, 995 reviews

Studio loft/ kitchenette/porch/bath

3 Miles from I75 exit 414 .studio apartment w/ porch over barn. Fire pit with wood available. Grill. Hammock swings under oaks. Stalls available. Close to riding/hiking trails in O'leno State Park. Close to springs for tubing/kayak/canoe. Ichetucknee Spring State Park, Ginny Springs, ++. Also 15 minutes from Santa Fe River and paddling/kayak/canoe rentals . Diving excursions available in High Springs. Quiet setting w/ pastures and grand daddy oaks.

Feb 1 – 8

G$16,691 GYD per night

Guest favorite

Guesthouse in Trenton

4.87 out of 5 average rating, 146 reviews

Springs capital of the world

Secluded, peaceful, country property in the heart of springs country. Come relax, enjoy the peace and quiet and the bright stars. This cabin offers everything you need. This is our farm where we have free roaming chickens, dogs and cats. Your well behaved small pets are more than welcome to join you during your visit. There are many springs nearby, all within 10-30 minutes away. Escape from the city and enjoy the tranquil country life.

Dec 25 – Jan 1

G$23,464 GYD per night

Guest favorite

Guesthouse in Archer

4.97 out of 5 average rating, 118 reviews

Your own private space of peace and quiet.

Keep it simple at this peaceful and centrally-located place. While being only 15 miles from the nightlife of downtown Gainesville, this is country living at it best. With no street lights the stars are bright and easily counted. The mornings are bright and full of the music of bird songs. The cute 2 bedroom apartment is on the SECOND FLOOR, it is easy to get lost in the whisper of the trees. This is a place to rest your soul and unwind.

Jan 16 – 23

G$20,365 GYD per night

Guest favorite

Guesthouse in Gainesville

4.95 out of 5 average rating, 105 reviews

Little Willa- an open plan guesthouse with kitchen

Kick back and relax in this calm, stylish space. Pet friendly and located in the quiet Duckpond neighborhood just a mile walk from the center of downtown Gainesville. Tom Petty Park at the end of our street includes playground, vollleyball net, tennis courts, dog park etc. Gainesville Bike Trail entrance just 1/2 mile from house. Private entrance to guesthouse with shared brick courtyard and parking.

Oct 15 – 22

G$30,113 GYD per night

Guest favorite

Guesthouse in Gainesville

4.94 out of 5 average rating, 112 reviews

Getaway Guesthouse

Cute, detached, studio-style guest house with private entrance. It is quiet and peaceful, but only minutes from the University of Florida, parks, and restaurants. Kitchen w/refrigerator, microwave, toaster oven, coffee-maker, and dining area perfect for enjoying breakfast before exploring. Comfortable Queen-sized bed for a goodnight's sleep.

May 13 – 20

G$15,116 GYD per night

Guest favorite

Guesthouse in Gainesville

4.99 out of 5 average rating, 193 reviews

Beautiful Cottage 10 Minute Walk from UF & Stadium

Beautifully renovated, spotless 1930's cottage is only a 10-minute walk from the University of Florida, Ben Hill Griffin Stadium, and the O'Connell Center. This gorgeous 1-bedroom cottage has it all: cathedral ceilings, new (2023) Sony Bravia LED TVs (55" & 50"), WiFi, new appliances and furnishings, and a full-sized washer & dryer.

Feb 10 – 17

G$20,300 GYD per night