
Boutique hotels in Gainesville
Find and book unique boutique hotels on Airbnb
Top-rated boutique hotels in Gainesville
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

La Chua - Sweetwater Branch Inn
This is a new Florida Cottage located on the south side of the Sweetwater property. This modern, pet-friendly cottage with a king-size bed, shower and bathtub combo, also features a full kitchen. The La Chua kitchen includes a microwave, full refrigerator with freezer and ice maker, oven with a stove top, coffee maker and dishwasher! The La Chau kitchen also has a table and chairs that overlooks the front yard. An extra room is located at the back of this cottage complete with a reading chair and a wall of windows so you can relax and unwind in this beautiful sun room! The La Chua Cottage has central A/C and heating with a private thermostat, free Wi-Fi, and one reserved parking space right next to the cottage.

Azalea Room at Magnolia Plantation
All rooms inside the main house have TV's, private baths, coffee makers. No children, pets or smoking allowed inside main house. Walking distance to many fine restaurants downtown and Depot Park in a quiet, safe neighborhood. This historic house was restored in 1991 and the owners live onsite. Breakfast is not a part of your stay. We are license and inspected. The owners live onsite to assure your stay is enjoyable.

Magnolia Room at Magnolia Plantation
The Baird Mansion was built in 1885 and has been decorated with period pieces while being updated with modern comforts. The Magnolia Room is the home's master bedroom and is still the home's largest. It has an entrance foyer and a private bath. It is surrounded by windows and has a fireplace. Breakfast is not a part of your stay. We are licensed, inspected and in complete compliance with all life safety codes.

Gardenia Room at Magnolia Plantation
The Gardenia Room invites you to sit & read a book in the bay windows, overlooking the tranquil gardens below. Step outside the 1885 mansion to roam the gardens or to the easily accessible downtown area & Depot Park. Breakfast is not a part of your stay. This property is inspected and licensed, in full compliance with all life safety codes. The owners live on property to be of your assistance.

Lake View King Guestroom near UF Campus | Sleeps 2
Relax in style with panoramic lake views from this King Guestroom at Hotel Eleo. Featuring a plush king bed, TVs, Nespresso coffee maker, mini fridge, and modern furnishings, this elegant space offers the perfect balance of comfort and sophistication. Located on the University of Florida campus near UF Health hospitals, guests enjoy a tranquil retreat close to everything Gainesville has to offer.

Comfortable King ADA Room near UF Campus
Enjoy accessible luxury in this modern King Guestroom at Hotel Eleo, designed with comfort and functionality in mind. This ADA-friendly room features a plush king bed, roll-in shower, and thoughtful accessibility details throughout. Located on the University of Florida campus near UF Health hospitals, this room offers the perfect blend of style, convenience, and inclusivity for every traveler.

Aurora's Room - Sweetwater Branch Inn
Aurora Room is located on the second floor of the historic McKenzie House. With its Asian-inspired decor and king-size bed, it is an unbeatable room. Note: this room is street side. May not be a good fit for light sleepers. This room is also able to connect to Giovanna Room if your friends or family want to tag along! Note: this room is street side and may not be suitable for light sleepers.

Hearing Accessible | 2 Queen Beds | Near UF Campus
Perfect for families or friends traveling together, this City View Two Queen Guestroom at Hotel Eleo combines modern style with thoughtful comfort. Enjoy city views, two plush queen beds, a smart TV, mini fridge, and Nespresso coffee maker. Located on the University of Florida campus near UF Health hospitals, this guestroom is ideal for relaxation and convenience in Gainesville.

City View Guestroom near UF Campus | Sleeps 4
Experience comfort and modern design in this City View Two Queen Guestroom at Hotel Eleo. With two plush queen beds, TV, mini fridge, and an in-room Nespresso coffee maker, this room is ideal for families, friends, or campus visitors. Enjoy city views and thoughtful amenities while staying just steps from UF Health hospitals and the University of Florida campus.

Tiffany Suite - Sweetwater Branch Inn
Our Tiffany Suite located on the second floor of the Cushman-Colson house really has it all. Located near the balcony and reading nook, it has recently been updated to include a brand-new pull out couch. This room is classy and we have the clawfoot tub and chandelier to prove it. Note: this room is street side and may not be suitable for light sleepers.

Jasmine Room at Magnolia Plantation
Jasmine is the 1st floor room in our inn. This room was the original library & still shows that 1885 charm. There is an antique queen bed with love seat and TV/DVD player. The room has a private bath with an antique clawfoot tub. Breakfast is not a part of your stay. We are licensed & inspected. The owner lives on property for your assistance.

Lake View Two Queen Guestroom near UF Campus
Perfect for families or friends, the Lake View Two Queen Guestroom at Hotel Eleo offers modern comfort with scenic lake views. This room features two plush queen beds, a mini fridge, a Nespresso coffee maker, and TVs. Located on the University of Florida campus, it’s ideal for campus visits, medical stays, or weekend getaways in Gainesville.
Popular amenities for Gainesville boutique hotels
Family-friendly boutique hotels

Magnolia Room at Magnolia Plantation

Luisa's Room - Sweetwater Branch Inn

Jasmine Room at Magnolia Plantation

Cross Creek - Sweetwater Branch Inn

Comfortable King ADA Room near UF Campus

City View Guestroom near UF Campus | Sleeps 4

Tea Rose Room - Sweetwater Branch Inn

Aurora's Room - Sweetwater Branch Inn
Other boutique hotel vacation rentals

Magnolia Room at Magnolia Plantation

Luisa's Room - Sweetwater Branch Inn

Jasmine Room at Magnolia Plantation

City View Guestroom near UF Campus | Sleeps 4

Tea Rose Room - Sweetwater Branch Inn

Aurora's Room - Sweetwater Branch Inn

Lake View King Guestroom near UF Campus | Sleeps 2

La Chua - Sweetwater Branch Inn
Quick stats about boutique hotels in Gainesville

Total vacation rentals
Explore 20 vacation rentals in Gainesville

Nightly prices starting at
Gainesville vacation rentals start at G$22,977Â GYD per night before taxes and fees

Verified guest reviews
Over 590 verified reviews to help you choose

Vacation rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Gainesville vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Gainesville rentals

4.8 Average rating
Gainesville stays are highly rated by guests—averaging 4.8 out of 5!

Nearby attractions
Gainesville's top spots, include Depot Park, Florida Museum of Natural History, and Royal Park Stadium 16
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- Boutique hotels Alachua County
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- Ginnie Springs
- Ocala National Forest
- Rainbow Springs State Park
- Manatee Springs State Park
- Ichetucknee Springs State Park
- Gilchrist Blue Springs State Park
- Paynes Prairie Preserve State Park
- World Equestrian Center
- Depot Park
- Fanning Springs State Park
- Ravine Gardens State Park
- Florida Museum of Natural History
- Lochloosa Lake
- The Canyons Zip Line and Adventure Park
- K P Hole Park
- Cedar Lakes Woods & Gardens
- Florida Horse Park
- Sholom Park
- Devil's Millhopper Geological State Park
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- Samuel P Harn Museum of Art
- Osceola National Forest
- Don Garlits Museum of Drag Racing
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