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Vacation home rentals in Upstate South Carolina

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in Upstate South Carolina

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
Vacation home in Pisgah Forest
4.99 out of 5 average rating, 101 reviews

Wake surrounded by views of the beautiful Blue Ridge Mountains in this lovely 1 bedroom vacation home.

Forget your worries in this spacious and serene space with indoor fireplace,full kitchen,laundry room,air, covered parking,large deck and outdoor fire pit/dining area. Minutes from hiking,biking,fishing,golf, 200+ waterfalls, dining, downtown Brevard, shopping,local breweries. Located between Pisgah National and DuPont State Forests. 30 minutes from Asheville airport and 20 minutes from historic Hendersonville. Brevard Music Center, Cradle of Forestry,Flat Rock Playhouse, Biltmore House nearby

Guest favorite
The modern cabin is nestled among trees, elevated on stilts, and features a spacious covered deck that invites outdoor enjoyment. Large windows reflect the greenery, allowing for natural light to enhance the welcoming design. A serene forest backdrop complements the structure.
Vacation home in Pisgah Forest
4.86 out of 5 average rating, 109 reviews

PILOT COVE Studio - Modern Luxury w/ Nature!

Directly bordering Pisgah National Forest at the Highway 276 gateway, Pilot Cove offers unrivaled access to Pisgah's renowned trails, roadways, rock walls, and trophy waters. Our luxury forest lodging cabins feature these amenities: - Modern Design - Upscale Finishes - Full Kitchen - Full Bathroom - Washer / Dryer - Perfect Sleeper Mattresses - Luxury Microfiber Linens - 48″ Flatscreen TV - Cable w/ 200+ Channels - Free Wi-Fi - Parking at each unit - Spacious Covered Deck - Bike Wash Station

Superhost
Vacation home in Greenville
4.77 out of 5 average rating, 26 reviews

Studio in the heart of Greenville

We look forward to hosting you at this centrally located studio apartment only 2 miles from Furman University and 6 miles from downtown Greenville and TR, in a quiet established neighborhood beautifully landscaped. Spacious studio with sitting area & built in office, HS Wi-Fi, *NO TV*! Full size wroght iron bed with pillow top mattress, comfy couch, and lots of natural light. In unit laundry. Kitchenette amenities - toaster oven, 2 burner hot plate and hot water kettle, French Pressed Coffee.

Top guest favorite
Vacation home in Bryson City
4.97 out of 5 average rating, 91 reviews

Nantahala River 2BR - Bear Cave Boat Parade

Closest rental to the Nantahala Outdoor Center! 1.5 miles upriver. Trains daily. Read this: NO SMOKING, NO PETS, no exceptions, please don't ask. Service animal excepted. Read CANCELLATION POLICY before booking and house rules before booking. NO TRASH SERVICE in area, guest must remove when checking out. NO TRAILERS. Parking too small Two vehicles MAX. NOT SAFE for small children due to powerful water. WI-FI provided. CELL Coverage: Verizon = Excellent. T Mobile = None. ATT = Outdoors only.

Superhost
Vacation home in Bryson City
4.77 out of 5 average rating, 73 reviews

Bear Kottage

This cottage is so cozy, most people call it the "Honeymoon Kottage." Bear Kottage sits right on the beautiful Alarka Creek; you can walk out your door and fish right in your back yard. This is a great little cottage for those wishing to do a little fishing, wading in the creek, or simply relax beside the beauty of the water from the comfort of their porch rockers or hot tub. Bear Kottage is located about seven miles from downtown Bryson City, which is about a 20-minute drive. WIFI available

Guest favorite
A welcoming blue front door is set against light beige siding. Flanking the door are two decorative planters containing lush greenery. A vertical sign reading 'WELCOME' stands beside the door, enhancing the inviting entrance.
Vacation home in Roebuck
4.9 out of 5 average rating, 105 reviews

Patriot Point B, an inviting studio apartment

This patriot themed studio apartment sleeps 5. The apartment includes a queen, pull out queen sofa bed, optional roll out full bed, a full kitchen, 1 bathroom, full laundry area, with areas for relaxing, bonfire and a gas grill. The apartment offers cozy patriotic decor including several historic homes in the area. It's charming and includes a large room with designated areas for the bed and living area, a kitchen and separate bath. We are minutes from downtown Spartanburg. Kerri & Brian

Top guest favorite
A gravel driveway leads to a charming detached building surrounded by trees, with a rustic exterior and a welcoming pathway. Natural light filters through the leaves, creating a serene atmosphere that invites exploration.
Vacation home in Tryon
4.99 out of 5 average rating, 124 reviews

Sandy Plains Fountain Home | King Bed | 3 MI TIEC

2 Bedrooms - 1 king bed & 1 queen, 1 bath Efficiency kitchen ( we are testing an additional space that we have recently added as another bedroom as an extra bonus room ) there will be an extra 100$ added separately by the host for use of 3rd bedroom- 2 night minimum Detached Laundry facility on property where nature surrounds you with additional outside seating & dining . Peaceful and centrally-located 3 miles from Tryon International Equestrian Center TIEC & local wineries .

Top guest favorite
Vacation home in Anderson
4.99 out of 5 average rating, 112 reviews

Lake House and Dock Upscale and Immaculate

Our immaculate 2020 built water-themed home is a luxury furnished lakefront 1.1 acre property on Lake Hartwell with a large boat dock. Our house enjoys amazing lake views and is perfect for the tournament fisherman, the boating enthusiast, golfers, families and those just needing to relax. We are down the street from Stonecreek Cove Golf Course in a countryside atmosphere and are comfortably close to the renowned Green Pond Landing, host to many national fishing tournaments.

Guest favorite
A firepit area is surrounded by a gravel base, featuring four wooden adirondack chairs. Lush trees frame the scene, while distant mountains and a cloudy sky create a serene backdrop. The warm glow of the fire contrasts with the cooler tones of the environment.
Vacation home in Morganton
4.83 out of 5 average rating, 89 reviews

Mountain Views w/ Hot Tub + Fire Pit – World’s Inn

Come escape to this newly-renovated 2/2, close to Morganton, Lake James, several breweries and wineries, a wedding venue and all the hiking and other outdoor activities in the state park the property backs up against. The house boasts every modern comfort you would need to work or play if you don’t want to unplug, but this house was meant to be enjoyed outdoors. The hot tub, screened porch, and fire-pit offer the perfect setting to enjoy the tranquility this house provides.

Guest favorite
The living area features a cozy sofa and recliner, with a wooden coffee table positioned on a patterned rug. A stone fireplace is complemented by a flat-screen TV. Natural light floods in through the glass doors leading to the balcony, and an open-area Jacuzzi tub is visible in the corner.
Vacation home in Gatlinburg
4.77 out of 5 average rating, 137 reviews

Stream side condo*Peaceful views+sounds*

154 Village Stream in Chalet Village - A romantic getaway, perfect for couples who want a peaceful, natural setting with easy access to Gatlinburg and the Smokies. It’s one of my favorite places to be on the private back deck listening to the sounds of water & nature. Our space is clean & cozy. Nothing fancy. Perfectly meant for simple people:) We did do upgrades, new decor, and furnishings since photos! Brand new larger water heater installed Dec 2023.

Top guest favorite
A covered dock with two boat slips is positioned over calm waters. Surrounding trees reflect in the lake, enhancing the natural scenery. A clear sky with scattered clouds provides a serene backdrop for an enjoyable waterfront experience.
Vacation home in Fair Play
4.97 out of 5 average rating, 67 reviews

Lakefront Hartwell Home w/NEW Dock + NEW Fire Pit

This 5 bedroom/3.5 bath house sleeps 14 and is perfect if you enjoy all of the amenities of a resort + the perks of a quiet, private home. Resort-style amenities include: a new covered dock with two boat slips, kayak, paddleboards, stone fire pit, NEW Hot Tub, stacked porches with ample seating and dining spaces, two indoor fireplaces, a full kitchen and a kichenette, comfortable beds, a serene gazebo - all nestled in the natural beauty of Lake Hartwell.

Top guest favorite
Vacation home in Seneca
4.98 out of 5 average rating, 63 reviews

Lakefront Clemson Retreat - 4 bedroom & 4 bathroom

Enjoy a light and modern lakefront retreat - 4 bedrooms and 4 bathrooms near Clemson's Memorial Stadium (Death Valley) and downtown Clemson. Harts Cove is 1 mile from Hartwell Village with restaurants and shopping on Clemson Blvd! There is a pool, work-out room, pool table and two docks on Lake Hartwell! There is a basketball and volleyball court and an outdoor fireplace for your enjoyment!

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