
Vacation home rentals in Upstate South Carolina
Find and book unique vacation home rentals on Airbnb
Top-rated vacation home rentals in Upstate South Carolina
Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

Wake surrounded by views of the beautiful Blue Ridge Mountains in this lovely 1 bedroom vacation home.
Forget your worries in this spacious and serene space with indoor fireplace,full kitchen,laundry room,air, covered parking,large deck and outdoor fire pit/dining area. Minutes from hiking,biking,fishing,golf, 200+ waterfalls, dining, downtown Brevard, shopping,local breweries. Located between Pisgah National and DuPont State Forests. 30 minutes from Asheville airport and 20 minutes from historic Hendersonville. Brevard Music Center, Cradle of Forestry,Flat Rock Playhouse, Biltmore House nearby
FamilyLocationCondition
4.99 out of 5 average rating, 116 reviews
Clemson/Anderson Lake Hartwell
Beautiful lake house for family fun in wonderful neighborhood, 15 minutes from Clemson. 2 kings, 2 queens , 2 doubles, crib, pack&play, Roll out toddler cots. Well equipped kitchen. Gas logs in living room. Wonderful deck with outdoor table and plenty of chairs for relaxing and enjoying views. Huge dining table seats 8 to 10. Antique bar in den. Large den has sectional sofa and 4 LazyBoy recliners Fire pit , grill , hot tub. Deck has nice view of lake. Dock has 2 double kayaks Enjoy!
FamilyLocationIndoor spaces
4.96 out of 5 average rating, 23 reviews
PILOT COVE Studio - Modern Luxury w/ Nature!
Directly bordering Pisgah National Forest at the Highway 276 gateway, Pilot Cove offers unrivaled access to Pisgah's renowned trails, roadways, rock walls, and trophy waters. Our luxury forest lodging cabins feature these amenities: - Modern Design - Upscale Finishes - Full Kitchen - Full Bathroom - Washer / Dryer - Perfect Sleeper Mattresses - Luxury Microfiber Linens - 48″ Flatscreen TV - Cable w/ 200+ Channels - Free Wi-Fi - Parking at each unit - Spacious Covered Deck - Bike Wash Station
ValueLocationAccess
4.86 out of 5 average rating, 109 reviews
Cozy cottage 15 mins Clemson, 7 mins lake Keowee
Has Stairs This efficiency apt has it all. Kitchen with convection micro, fridge, coffee maker & hot plate. Not a full size home, it’s an apartment. Space surrounded by Oconee County Country Club golf course. 1 mile to Walmart and shopping. 30 mins to the Blue Ridge Mountains. We are 7 mins to beautiful Lake Keowee. Please note 5 people should be family as it is tight. The person booking the property must be staying on the property. No construction equipment or trucks allowed on the property.
LocationFamilySleep quality
4.93 out of 5 average rating, 61 reviews
Studio in the heart of Greenville
We look forward to hosting you at this centrally located studio apartment only 2 miles from Furman University and 6 miles from downtown Greenville and TR, in a quiet established neighborhood beautifully landscaped. Spacious studio with sitting area & built in office, HS Wi-Fi, *NO TV*! Full size wroght iron bed with pillow top mattress, comfy couch, and lots of natural light. In unit laundry. Kitchenette amenities - toaster oven, 2 burner hot plate and hot water kettle, French Pressed Coffee.
ValueFamilyQuiet
4.8 out of 5 average rating, 30 reviews
Bike from House! Rocky Ridge Base Camp at DuPont
Quiet 6.5-acre retreat at DuPont State Forest! Perfect for bikers & hikers, & people seeking solitude. This updated home comfortably sleeps 5. Enjoy a fully equipped kitchen, wood stove in the living room, and a large covered deck with a grill. Hidden away near Sky Valley Road, this is a super quiet spot with easy access to world-class trails. Being able to bike right from the house into DuPont, with a garage makes this the ultimate biking basecamp. Close to Brevard/Pisgah & Kanuga, too.
FamilyLocationLong stay
5.0 out of 5 average rating, 85 reviews
Bear Kottage
This cottage is so cozy, most people call it the "Honeymoon Kottage." Bear Kottage sits right on the beautiful Alarka Creek; you can walk out your door and fish right in your back yard. This is a great little cottage for those wishing to do a little fishing, wading in the creek, or simply relax beside the beauty of the water from the comfort of their porch rockers or hot tub. Bear Kottage is located about seven miles from downtown Bryson City, which is about a 20-minute drive. WIFI available
LocationFamilyHeating
4.8 out of 5 average rating, 90 reviews
Patriot Point B, an inviting studio apartment
This patriot themed studio apartment sleeps 5. The apartment includes a queen, pull out queen sofa bed, optional roll out full bed, a full kitchen, 1 bathroom, full laundry area, with areas for relaxing, bonfire and a gas grill. The apartment offers cozy patriotic decor including several historic homes in the area. It's charming and includes a large room with designated areas for the bed and living area, a kitchen and separate bath. We are minutes from downtown Spartanburg. Kerri & Brian
LocationFamilyAmenities
4.9 out of 5 average rating, 105 reviews
The Parlor #1
Come relax and enjoy life in the country! Our Airbnb is a renovated milking parlor! While the dairy is no longer in operation, we have beef cattle, donkeys, and horses that you may see as you sit and enjoy your coffee on the porch! Price reflects for 2 ppl, added fee for more than 2 due to added laundry etc. One queen bed, 2 single floor mattresses. 6 minutes to Abbeville, 12 minutes to Due West For traveling, nurses or those wanting to stay a month or more, we offer discounted rates!
LocationValueCheck-in
5.0 out of 5 average rating, 31 reviews
Summers are best spent at the lake
*No cleaning fee. Peaceful lakefront home with gentle slope toward the water with a large dock for your boat, sunbathing or morning coffee. The completely renovated 2 bedroom/1 bath home has an outdoor covered kitchen perfect for family meals. The 20x40 ft deck off the kitchen provides plenty of space for entertaining, playing or an outdoor movie! We have several kayaks, paddleboard, water tubes, carpet islands and games to build memories to last a lifetime. 4 night minimum May-August.
LocationFamilyOutdoor spaces
5.0 out of 5 average rating, 40 reviews
Sandy Plains Fountain Home | King Bed | 3 MI TIEC
2 Bedrooms - 1 king bed & 1 queen, 1 bath Efficiency kitchen ( we are testing an additional space that we have recently added as another bedroom as an extra bonus room ) there will be an extra 100$ added separately by the host for use of 3rd bedroom- 2 night minimum Detached Laundry facility on property where nature surrounds you with additional outside seating & dining . Peaceful and centrally-located 3 miles from Tryon International Equestrian Center TIEC & local wineries .
LocationValueParking
4.99 out of 5 average rating, 143 reviews
Quiet Mountain Retreat
Kick back and relax in this calm, country atmosphere close to Dupont and Pisgah forests. We're on a beautiful road for biking and walks. There are hiking trails and a creek on the property for hikes with the family and pets. For all the bikers out there, we’re on the Belgian Waffle Ride Trail for North Carolina. There are a number of great restaurants and breweries in Hendersonville and Brevard.
LocationValueTV
4.96 out of 5 average rating, 79 reviewsPopular amenities for Upstate South Carolina vacation home rentals
Family-friendly vacation home rentals

Wolf's Den
LocationValueQuiet
4.76 out of 5 average rating, 76 reviews
PILOT COVE 1 BR - Modern Luxury w/ Nature!
LocationValueCleanliness
4.8 out of 5 average rating, 81 reviews
PILOT COVE Studio - Modern Luxury w/ Nature!
LocationValueNearby
4.94 out of 5 average rating, 87 reviews
Wake surrounded by views of the beautiful Blue Ridge Mountains in this lovely 1 bedroom vacation home.
ValueLocationDecor
4.99 out of 5 average rating, 116 reviews
Sandy Plains Fountain Home | King Bed | 3 MI TIEC
ValueLocationTV
4.99 out of 5 average rating, 143 reviews
Patriot Point B, an inviting studio apartment
ValueFamilyCheck-in
4.9 out of 5 average rating, 105 reviews
PILOT COVE 2 BR - Modern Luxury w/ Nature!
LocationValuePets
4.89 out of 5 average rating, 111 reviews
PILOT COVE Studio - Modern Luxury w/ Nature!
FamilyLocationCondition
4.86 out of 5 average rating, 109 reviewsVacation home rentals with a patio

Private mountain oasis with stunning views
FamilyValueCleanliness
5.0 out of 5 average rating, 37 reviews
Cozy Lake Hartwell Home 25 Minutes from Clemson
LocationFamilyIndoor spaces
5.0 out of 5 average rating, 16 reviews
Cozy Cottage on the Creek w Jetted Tub
ValueLocationHospitality
4.65 out of 5 average rating, 23 reviews
'Lakefront Haven' and mountain views in Sapphire!
LocationValueCondition
4.6 out of 5 average rating, 15 reviews
Fully furnished newly renovated 1b/1b Mtn Townhome
LocationDecorNearby
5.0 out of 5 average rating, 3 reviews
PILOT COVE Studio: Modern Luxury with Nature
LocationParkingIndoor spaces
4.93 out of 5 average rating, 14 reviews
PILOT COVE 1 BR - Modern Luxury w/ Nature!
ValueLocationNearby
4.67 out of 5 average rating, 9 reviews
PILOT COVE Studio: Modern Luxury with Nature
ValueLocationOutdoor spaces
4.57 out of 5 average rating, 7 reviewsVacation home rentals with a washer and dryer

Lirio Woods
ValueFamilyView
4.88 out of 5 average rating, 72 reviews
Wright House Retreat
ValueLocationGrill
4.94 out of 5 average rating, 82 reviews
Stunning Mtn Views in Western NC W/new hot tub
LocationFamilyCondition
4.95 out of 5 average rating, 21 reviews
Lakefront 4BR with dock, kayaks, lake toys
FamilyLocationAmenities
4.95 out of 5 average rating, 22 reviews
Brookside at Beech Haven Suite 1 & 2 combined
LocationFamilyNearby
4.81 out of 5 average rating, 88 reviews
Chipmunk Holler
LocationFamilyAccess
4.84 out of 5 average rating, 37 reviews
River City Oasis

PILOT COVE 2 BR - Modern Luxury w/ Nature!
ValueFamilyRiver
4.89 out of 5 average rating, 111 reviewsDestinations to explore
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- Clemson University
- Blue Ridge Parkway
- Tryon International Equestrian Center
- Table Rock State Park
- The North Carolina Arboretum
- Chimney Rock State Park
- Gorges State Park
- Devils Fork State Park
- Lake Lure Beach and Water Park
- DuPont State Forest
- Bon Secours Wellness Arena
- Saint Paul Mountain Vineyards
- Jump Off Rock
- Fred W Symmes Chapel
- Fluor Field at the West End
- Jones Gap State Park
- Falls Park On The Reedy
- Peace Center
- Carl Sandburg Home National Historic Site
- Whitewater Falls
- Overmountain Vineyards
- Oconee State Park
- Furman University
- Memorial Stadium, Clemson
- Things to do Upstate South Carolina
- Art workshops Upstate South Carolina
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- Cooking South Carolina
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