Vacation home rentals in Upstate South Carolina

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in Upstate South Carolina

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious living area features a comfortable sofa with a light-colored fabric, paired with a wooden coffee table adorned with greenery. A sloped ceiling adds dimension, while a warm neutral palette and natural light enhance the inviting feel of the space.
Vacation home in Pisgah Forest

Wake surrounded by views of the beautiful Blue Ridge Mountains in this lovely 1 bedroom vacation home.

Forget your worries in this spacious and serene space with indoor fireplace,full kitchen,laundry room,air, covered parking,large deck and outdoor fire pit/dining area. Minutes from hiking,biking,fishing,golf, 200+ waterfalls, dining, downtown Brevard, shopping,local breweries. Located between Pisgah National and DuPont State Forests. 30 minutes from Asheville airport and 20 minutes from historic Hendersonville. Brevard Music Center, Cradle of Forestry,Flat Rock Playhouse, Biltmore House nearby

FamilyValueHiking

4.99 out of 5 average rating, 116 reviews
Guest favorite
A view of the outdoor space features a circular arrangement of red chairs surrounding a central fire pit, positioned near a grassy area and a swing set. The backdrop includes a serene lake and lush trees, enhancing the natural setting.
Vacation home in Anderson

Clemson/Anderson Lake Hartwell

Beautiful lake house for family fun in wonderful neighborhood, 15 minutes from Clemson. 2 kings, 2 queens , 2 doubles, crib, pack&play, Roll out toddler cots. Well equipped kitchen. Gas logs in living room. Wonderful deck with outdoor table and plenty of chairs for relaxing and enjoying views. Huge dining table seats 8 to 10. Antique bar in den. Large den has sectional sofa and 4 LazyBoy recliners Fire pit , grill , hot tub. Deck has nice view of lake. Dock has 2 double kayaks Enjoy!

FamilyLocationOutdoor spaces

4.96 out of 5 average rating, 23 reviews
Guest favorite
The modern cabin is elevated on stilts, surrounded by trees. A spacious covered deck features two outdoor chairs. The large glass doors open to reveal the inviting interior, showcasing the well-equipped kitchen and dining area behind. Natural light illuminates the space.
Vacation home in Pisgah Forest

PILOT COVE Studio - Modern Luxury w/ Nature!

Directly bordering Pisgah National Forest at the Highway 276 gateway, Pilot Cove offers unrivaled access to Pisgah's renowned trails, roadways, rock walls, and trophy waters. Our luxury forest lodging cabins feature these amenities: - Modern Design - Upscale Finishes - Full Kitchen - Full Bathroom - Washer / Dryer - Perfect Sleeper Mattresses - Luxury Microfiber Linens - 48″ Flatscreen TV - Cable w/ 200+ Channels - Free Wi-Fi - Parking at each unit - Spacious Covered Deck - Bike Wash Station

LocationValueAccuracy

4.86 out of 5 average rating, 109 reviews
Guest favorite
An efficiency kitchen is visible, featuring a convection microwave, refrigerator, and coffee maker on a smooth countertop. A small dining area with a table and four chairs is nearby. A cozy armchair occupies a corner, while a doorway leads to a bathroom space with a shower.
Vacation home in Seneca

Cozy cottage 15 mins Clemson, 7 mins lake Keowee

Has Stairs This efficiency apt has it all. Kitchen with convection micro, fridge, coffee maker & hot plate. Not a full size home, it’s an apartment. Space surrounded by Oconee County Country Club golf course. 1 mile to Walmart and shopping. 30 mins to the Blue Ridge Mountains. We are 7 mins to beautiful Lake Keowee. Please note 5 people should be family as it is tight. The person booking the property must be staying on the property. No construction equipment or trucks allowed on the property.

LocationValueIndoor spaces

4.93 out of 5 average rating, 61 reviews
Superhost
Vacation home in Greenville

Studio in the heart of Greenville

We look forward to hosting you at this centrally located studio apartment only 2 miles from Furman University and 6 miles from downtown Greenville and TR, in a quiet established neighborhood beautifully landscaped. Spacious studio with sitting area & built in office, HS Wi-Fi, *NO TV*! Full size wroght iron bed with pillow top mattress, comfy couch, and lots of natural light. In unit laundry. Kitchenette amenities - toaster oven, 2 burner hot plate and hot water kettle, French Pressed Coffee.

LocationValueCheck-in

4.8 out of 5 average rating, 30 reviews
Top guest favorite
Vacation home in Hendersonville

Bike from House! Rocky Ridge Base Camp at DuPont

Quiet 6.5-acre retreat at DuPont State Forest! Perfect for bikers & hikers, & people seeking solitude. This updated home comfortably sleeps 5. Enjoy a fully equipped kitchen, wood stove in the living room, and a large covered deck with a grill. Hidden away near Sky Valley Road, this is a super quiet spot with easy access to world-class trails. Being able to bike right from the house into DuPont, with a garage makes this the ultimate biking basecamp. Close to Brevard/Pisgah & Kanuga, too.

LocationFamilyTV

5.0 out of 5 average rating, 85 reviews
Guest favorite
A cottage with a metal roof is set against a backdrop of trees and rolling hills. A gravel pathway leads to the front porch, flanked by landscaped flower beds and a tall evergreen. A clear creek can be seen in the distance, enhancing the serene environment.
Vacation home in Bryson City

Bear Kottage

This cottage is so cozy, most people call it the "Honeymoon Kottage." Bear Kottage sits right on the beautiful Alarka Creek; you can walk out your door and fish right in your back yard. This is a great little cottage for those wishing to do a little fishing, wading in the creek, or simply relax beside the beauty of the water from the comfort of their porch rockers or hot tub. Bear Kottage is located about seven miles from downtown Bryson City, which is about a 20-minute drive. WIFI available

FamilyLocationPets

4.8 out of 5 average rating, 90 reviews
Guest favorite
A welcoming blue front door is set against light beige siding. Flanking the door are two decorative planters containing lush greenery. A vertical sign reading 'WELCOME' stands beside the door, enhancing the inviting entrance.
Vacation home in Roebuck

Patriot Point B, an inviting studio apartment

This patriot themed studio apartment sleeps 5. The apartment includes a queen, pull out queen sofa bed, optional roll out full bed, a full kitchen, 1 bathroom, full laundry area, with areas for relaxing, bonfire and a gas grill. The apartment offers cozy patriotic decor including several historic homes in the area. It's charming and includes a large room with designated areas for the bed and living area, a kitchen and separate bath. We are minutes from downtown Spartanburg. Kerri & Brian

FamilyLocationLayout

4.9 out of 5 average rating, 105 reviews
Top guest favorite
Vacation home in Abbeville

The Parlor #1

Come relax and enjoy life in the country! Our Airbnb is a renovated milking parlor! While the dairy is no longer in operation, we have beef cattle, donkeys, and horses that you may see as you sit and enjoy your coffee on the porch! Price reflects for 2 ppl, added fee for more than 2 due to added laundry etc. One queen bed, 2 single floor mattresses. 6 minutes to Abbeville, 12 minutes to Due West For traveling, nurses or those wanting to stay a month or more, we offer discounted rates!

ValueLocationIndoor spaces

5.0 out of 5 average rating, 31 reviews
Top guest favorite
An open-concept living area presents a spacious kitchen with modern white cabinetry and an island with seating. A comfortable brown couch is situated nearby, with natural light filtering through large glass doors leading to the deck. Decorative elements enhance the minimalist design.
Vacation home in Fair Play

Summers are best spent at the lake

*No cleaning fee. Peaceful lakefront home with gentle slope toward the water with a large dock for your boat, sunbathing or morning coffee. The completely renovated 2 bedroom/1 bath home has an outdoor covered kitchen perfect for family meals. The 20x40 ft deck off the kitchen provides plenty of space for entertaining, playing or an outdoor movie! We have several kayaks, paddleboard, water tubes, carpet islands and games to build memories to last a lifetime. 4 night minimum May-August.

ValueFamilyComfort

5.0 out of 5 average rating, 40 reviews
Top guest favorite
A gravel driveway leads to a charming detached building surrounded by trees, with a rustic exterior and a welcoming pathway. Natural light filters through the leaves, creating a serene atmosphere that invites exploration.
Vacation home in Tryon

Sandy Plains Fountain Home | King Bed | 3 MI TIEC

2 Bedrooms - 1 king bed & 1 queen, 1 bath Efficiency kitchen ( we are testing an additional space that we have recently added as another bedroom as an extra bonus room ) there will be an extra 100$ added separately by the host for use of 3rd bedroom- 2 night minimum Detached Laundry facility on property where nature surrounds you with additional outside seating & dining . Peaceful and centrally-located 3 miles from Tryon International Equestrian Center TIEC & local wineries .

ValueLocationKitchen

4.99 out of 5 average rating, 143 reviews
Top guest favorite
A serene landscape is visible through a natural clearing, showcasing trees in soft morning light. The sun rises in the background, hinting at a peaceful day. A grassy area frames the image, while a pathway can be seen winding through the forest.
Vacation home in Hendersonville

Quiet Mountain Retreat

Kick back and relax in this calm, country atmosphere close to Dupont and Pisgah forests. We're on a beautiful road for biking and walks. There are hiking trails and a creek on the property for hikes with the family and pets. For all the bikers out there, we’re on the Belgian Waffle Ride Trail for North Carolina. There are a number of great restaurants and breweries in Hendersonville and Brevard.

FamilyLocationAmenities

4.96 out of 5 average rating, 79 reviews

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