
House vacation rentals in Upstate South Carolina
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Top-rated house rentals in Upstate South Carolina
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A Tranquil Place (near downtown Greenville)
A Tranquil Space is conveniently located close to Downtown Greenville. The large suite includes the bedroom, living area, kitchenette (fridge/freezer/convection oven), bathroom, and study/eating area. It is newly renovated area on the end of my home with a private entrance. The space is welcoming and inviting...a perfect space to get away from the hustle. Although minutes from Downtown, the suite feels like you're in the mountains with a private back yard and many trees. Enjoy your stay!

Modern Wooded Retreat
Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

Greenville GEM Luxurious Retreat in Prime Location
Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Spectacular home 1 mile from Main St Greenville!
Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

Cabin I Private hiking trails | Hot Tub I Sauna
Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Greenville Modern Retreat - 8 minutes to Downtown
Decorated in a mid century modern theme, this home is perfect for couples and business travelers looking for a peaceful, modern aesthetic filled with natural light. This home is located in San Souci just 2.5 mi (8min drive) to downtown Greenville. It is also conveniently located 1/2 mi to the Swamp rabbit trail and the Swamp Rabbit Grocery. Please see “Where you’ll be” section for further description of location and the neighborhood. We're excited to have you join us!

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Villa Rose-On 2 Acres. FP, King Bed, 1mi Biltmore
Chic Modern, Luxurious, Cozy-styled & Large private KING Bed & Barn view one-bedroom in-law apt. (1,050 sqft) w/ Fireplace. On 2 Beautiful Acres under towering trees, while only being 3 min.(1 mi) to the Biltmore Estate. 5-min. (4 mi) to the Heart of Downtown Asheville, NC; Blue Ridge Parkway, & South Slope DT breweries, coffee houses, and restaurants. Romantic, Quiet, Retreat Cottage, Nestled in Nature. A unique gem, close to it all

Sunset Point-Best view on Broadway - HOT TUB!
This gorgeous property is situated on the picturesque Broadway Lake in Anderson, SC, offering 300 acres of pristine water ideal for pontoon rides, fishing, and making unforgettable memories. This tiered lot boasts an impressive 100 feet of water frontage and a private dock, complete with four kayaks (3 single and one tandem), two paddle boards, and various floats and water fun for guests to explore the lake at their leisure.

GVL Historic Luxury-Walk to Downtown/Swamp Rabbit
Welcome to Natural Light Delight, your bright and inviting stay in Greenville’s charming Pettigru Historic District. High ceilings and large windows fill the space with natural light, creating a calm, welcoming atmosphere. You’ll be in one of Greenville’s most walkable neighborhoods — just minutes walk from the Swamp Rabbit Trail, Downtown, and the city’s best restaurants, shops, and parks.

Deluxe Downtown Bungalow, fenced yard!
A true Brevard downtown locals luxury experience. This beautiful home sits in the vibrant heart of the lumber yard arts district and sleeps seven-plus in two bedrooms. Enjoy two full luxury baths, a fully equipped gourmet kitchen, a large dining room, a cozy living room with a gas fireplace, a fenced-in yard for pets, and ample parking. It is a short walk or ride to EVERYTHING BREVARD!

Slate Roof Cottage~Farm Animals!
Take it easy at this unique and tranquil getaway in the country. Relax on the porch swing or take a walk and say hello to our farm animals. We are in the country and are certain that you will enjoy a peaceful visit. 10 miles to Historic Abbeville 5 miles to Erskine College 18 miles - Heyward Manor wedding venue 10 minutes to Diamond Hill Mine 30 minutes to Greenwood or Anderson
Popular amenities for Upstate South Carolina house rentals
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!

A-frame retreat w/ hot tub & views

Estate-Like Retreat/ Walk to Town /Hot Tub & Pool

HOT TUB Sleeps 11 Gameroom Cozy Getaway

Wonderful mountain cottage with amazing view!

Shalom House with Pool near DT Greer SC

A quiet place in the country

Spacious 3 BR house with private backyard.
Weekly house rentals

Modern Cabin | Hot Tub | Fire Pit | Dog friendly

Treehouse / A-Frame with Fire Pit

Fire Pit & Creek in the backyard!

Villa Nirvana, Serene, Secluded, Beautiful Views!

Lake Hartwell House - Cozy and Close to Clemson!

Modern Farmhouse in Downtown Simpsonville, SC

Family & Pet Friendly Home - Sleeps 8

Happy Place on Rich Mountain
Private house rentals

The Green Cottage

Modern Cottage in the Woods w/ Hot Tub & Firepit

Spacious Lakefront *Gem* Pet & Family Friendly

Bohemian Bungalow

Modern Pet Friendly Stay near Bridgeway Fire pit

Modern Mountain Asheville Getaway/ Hot Tub

Heart of Fountain Inn: 2BR Gem

West End Cottage
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- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Chimney Rock State Park
- Ski Sapphire Valley
- Table Rock State Park
- Lake Lure Beach and Water Park
- Clemson University
- Jump Off Rock
- Tryon International Equestrian Center
- Carl Sandburg Home National Historic Site
- Saint Paul Mountain Vineyards
- Bon Secours Wellness Arena
- Burntshirt Vineyards
- Overmountain Vineyards
- DuPont State Forest
- Falls Park On The Reedy
- Devils Fork State Park
- Jones Gap State Park
- Peace Center
- Fred W Symmes Chapel
- Paris Mountain State Park
- Looking Glass Falls
- Oconee State Park
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