
House vacation rentals in Upstate South Carolina
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Top-rated house rentals in Upstate South Carolina
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Atrium House - Spa Retreat
Come unwind and breathe at our couples mountain spa retreat. Atrium House has been designed to feel open to the lovely mountain surroundings yet let you relax in privacy. Our outdoor therapy hot tub, indoor/outdoor gas fireplace, and spacious two-person, walk-in shower make for a getaway so tranquil, you may never make it in to nearby Asheville! We're out in the country but just over a 15-minute drive from downtown Asheville, Biltmore, Hendersonville, Asheville Airport, and dozens of breweries.

Greenville GEM Luxurious Retreat in Prime Location
Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Luxurious 3BR on Lake Saluda w/ Kayaks, Fire Pit
Welcome to Lake Saluda Serenity, your tranquil lake house retreat just 15 minutes from Downtown Greenville! This stylish 3BR, 2BA haven combines modern aesthetics with breathtaking natural views. Revel in tranquility on the spacious patio or delve into adventures with provided kayaks and pedal boats. Explore lake life at your pace and soak in the serene surroundings. Nestled in an idyllic locale with top-notch amenities, it's your quintessential escape to lakefront luxury and modern comfort.

Grace Mountain Cottage-Mtn views /Peaceful+Private
Kick back and relax in this calm, stylish space. Escape to serenity at our mountain top cottage, 20 min to Asheville. Embrace panoramic mountain views from every corner of this charming retreat. Unwind by the outdoor firepit, roasting s'mores under the starlit sky. Enjoy al fresco dining with a backdrop of breathtaking sunsets. This cozy cottage sleeps 4, perfect for a family or friends seeking tranquility and nature's embrace. Experience the essence of mountain living in comfort and style!

Huge Views, Outdoor Tub, Fire Pit, Close to Town!
Perched at 4,200' high and under 10 minutes to downtown Highlands and Cashiers, this easily accessed, light filled, cabin offers massive, year-round, long range views of Whiteside &Rock Mountains from every room of the house as well as from our expansive decks! -10 Minutes to Downtown Highlands (shopping, dining, art culture) -8 Minutes to Cashiers Crossroads (Whiteside brewery, coffee, shopping) -5 Minutes to Whiteside Mountain trailhead -15 Minutes to Lake Glenville (Boat Rentals!)

Cabin I Private hiking trails | Hot Tub I Sauna
Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Orchard Hill Vintage Cottage
Come enjoy this magnificent view in Saluda! Relax in the swings or sit on the porch and enjoy the peacefulness. The fire pit under the stars is so Saludacrous! Our cozy cottage is just steps from Judds Peak and 2 miles from downtown, where there is always food and fun! The Gorge Zipline is located in our quaint little town and the Green River has hiking, tubing, kayaking, white water rafting, rock climbing! The towns of Hendersonville, Flat Rock and Asheville are just minutes away.

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Pumpkintown Mountain View Cottage
Welcome to Pumpkintown Mountain view Cottage, a 2 bedroom with 1 bath with a large porch and great views of Table Rock and Caesar's Head ridge line. Great location to stay for year-round outdoor activities from hiking (5 miles to Table Rock State Park) to swimming and festivals. We are located 20 minutes to Easley, City of Pickens and Travelers rest. This place has a mix of country, farm and Mountain life in one location so come and relax after a good day of outdoor activities.

The Dogwoods Upper at Vineyard Gap
Welcome to the Upper Dogwoods of Vineyard Gap, our Upper Unit offers panoramic views of mountains and forest, perfect for a serene escape. This handcrafted retreat features expansive windows that bring nature’s beauty inside, creating a secluded haven for couples or solo adventurers. If you’re traveling with friends or family, reach out about booking our two other unique units for a full experience. Enjoy the best view in The Dogwoods from this breathtaking vantage point!

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

GVL Historic Lux -Walk Dntwn/Swamp Rabbit/BonSecrs
Welcome to your bright and inviting stay in Greenville’s charming Pettigru Historic District. You’ll be in one of Greenville’s most walkable neighborhoods — just minutes walk from the Swamp Rabbit Trail, Downtown, Bon Secours Wellness Arena, and the city’s best restaurants, shops, and parks. High ceilings and large windows fill the space with natural light, creating a calm, welcoming atmosphere.
Popular amenities for Upstate South Carolina house rentals
House rentals with a pool

Shalom House with Pool near DT Greer SC

A quiet place in the country

Pool Gameroom Hot Tub Family Fun Getaway

10 minutes to downtown. Hot tub & billard room

Palmetto Escape -Family Friendly base 6.6 mi GVL

Amazing Views - Heated Pool - Hot Tub - Game Room

Lake house w/ a pool and Pickleball court

Keowee Key Luxury Condo - Stunning Views!
Weekly house rentals

Amazing Lakefront home with private NEW dock

Walk-to-Downtown Retreat | Creekside + Hot Tub

Nature Falls- Romantic Luxe, Waterfalls, Treehouse

Lake Front/firepit/kayaks/ game room & pool table

Sunset Point-Best view on Broadway - HOT TUB!

Airstream w/ Bathtub, River, & Hot Tub

Incredible waterfall mtn views| HotTub| FencedYARD

Creekside Cottage with Mountain Views
Private house rentals

Luxury Treehouse Retreat | Private Trails & Views!

Modern Mountain Stream Overlook

The Owl's Peak | Relaxing Smoky Mountain Escape

Lakefront w/Private Dock + Fenced Yard.

Tekoa at Table Rock

Modern Cottage in the Woods w/Hot Tub & Firepit

Welcome to River House

Beautiful, secluded, nestled in the woods+sauna!
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- Clemson University
- Blue Ridge Parkway
- Tryon International Equestrian Center
- Table Rock State Park
- The North Carolina Arboretum
- Chimney Rock State Park
- Gorges State Park
- Devils Fork State Park
- Lake Lure Beach and Water Park
- DuPont State Forest
- Bon Secours Wellness Arena
- Saint Paul Mountain Vineyards
- Jump Off Rock
- Fred W Symmes Chapel
- Fluor Field at the West End
- Jones Gap State Park
- Falls Park On The Reedy
- Peace Center
- Carl Sandburg Home National Historic Site
- Overmountain Vineyards
- Whitewater Falls
- Oconee State Park
- Furman University
- Memorial Stadium, Clemson
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