Pet-friendly vacation rentals in Upstate South Carolina

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Upstate South Carolina

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite

The A-frame cabin is situated among tall trees, showcasing natural wood elements and a sloped roof. A welcoming deck is visible at the front, surrounded by well-maintained paths and rustic landscaping, inviting guests to explore the serene woodland setting.

Cabin in Carlton

PrivateRiverView/AframeCabin/Goats/Fishing/Trails

South Fork River Cabin just below Watson Mill Bridge State Park, this A-Frame is a unique and tranquil escape. Perfect for a couple’s getaway, it features a king-size loft bed and peaceful river views. Adults only cabin Bring your beach towels and enjoy the chairs provided for relaxing on the sandbars and rocks in the river. In the pasture behind the cabin, our friendly goats love attention and are always happy to greet guests. We have been in a drought, so the river is very low at the moment

4.99 out of 5 average rating, 156 reviews

Top guest favorite

A custom log cabin with a spacious deck is nestled among tall hardwood trees. Sunlight filters through the foliage, highlighting the natural wood exterior and stone chimney. Surrounding greenery provides a serene forest setting, emphasizing the cabin's private and tranquil location.

Cabin in Marietta

Napaw Mountain Log Cabin~Magical Mt.Top Experience

Welcome to Napaw Mt. Log Cabin! A pet and kid friendly, custom built cabin tucked in 35 acres of hardwoods on a private mountain top.Wrap around decks lend a lovely view of Blue Ridge Mts. Relax in the hot tub(not open Jan/Feb)by the gas fire pit or build a fire in the fireplace on the deck. Lay in the lofts king sz log bed and take in a full window view of nature.The Cabin is only mins from the best hiking, biking, shopping,fine dining in Upstate SC~Table Rock,Pretty Place,Jones Gap,Greenville

4.96 out of 5 average rating, 142 reviews

Top guest favorite

A vibrant scene showcases two golden retrievers playing in a shallow stream, surrounded by lush green foliage. Behind them, a cascading waterfall flows over rocky tiers, creating a soothing sound and enhancing the natural beauty of the forested landscape.

Cabin in Oconee County

Secluded Waterfall Cabin.

Romantic, rustic cabin at the base of a 35-foot waterfall, nestled in the middle of 16 secluded acres surrounded by national forest that extends to the Chattooga River. This magical get-away caters to those with an adventurous spirit. Hike from the cabin to additional waterfalls, bike down Turkey Ridge Road to Opossum Creek Trail and the Five Falls or drive two miles to the Chattooga Belle Farm. The Waterfall Cabin is a joy to us all, and we hope you love it as much as we do. No cleaning fee.

4.99 out of 5 average rating, 398 reviews

Guest favorite

The outdoor area showcases a tranquil pool surrounded by lush greenery, with comfortable lounge chairs positioned nearby. A pastel sunset provides a serene backdrop, while inflatable pool accessories add a playful touch to the inviting atmosphere.

Home in Simpsonville

Luxury Retreat & Heated Pool Downtown Simpsonville

Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!

4.93 out of 5 average rating, 107 reviews

Top guest favorite

An aerial view of a spacious two-level brick home is presented, showcasing a large parking area in front with two garage doors visible. Surrounding greenery enhances the setting, while the property is bordered by trees, providing a sense of privacy.

Home in Anderson

Clemson Lake Hartwell Waterfront, Pontoon Rental

Come and enjoy a relaxing family vacation on beautiful Lake Hartwell in this spacious 2 level home. Plenty of room for multiple families to share. This 7600 sq. ft lakefront home sleep up to 18 featuring 7 bedrooms with 1 additional rooms with sofa beds; 5 full-sized bathrooms; 1 laundry area with 2 washers & 2 dryers. Each level boasts a fully furnished kitchen along with a large entertainment area. Breakfast area off main kitchen in addition to a spacious dining room that seats up to 10.

4.94 out of 5 average rating, 145 reviews

Top guest favorite

The exterior of the treehouse is showcased in twilight, highlighting a spacious deck with multiple seating areas. Lanterns illuminate the wood accents of the house, and large windows reflect the surrounding greenery. A dining table is arranged on the deck, set for enjoyable outdoor meals.

Treehouse in Highlands

Hide Inn Seek Hillside Treehouse 1.5mi to Main St

Escape to luxury at the Hillside Treehouse brought to you by the biophilic hospitality brand 'Hide Inn Seek'. Located in Highlands NC, just 1.5 miles from main street, this newly built home sits boldly among the trees allowing you to indulge in nature while enjoying luxury accommodations. The 58 step ascent leads you up to a treehouse experience like no other. Check out our newly listed sister property, Bird Nest Treehouse, designed just for couples—complete with a full spa experience!

4.97 out of 5 average rating, 173 reviews

Guest favorite

A deck area overlooking the river features wooden railings with metal accents. Several outdoor chairs are positioned on the deck, while the river flows gently beside it. Lush trees line the riverbank, providing a natural backdrop.

Tiny home in Easley

New! Riverfront Tiny Home - Downtown Greenville SC

The River House is a boutique tiny home on the river front of the Saluda with breathtaking views - just 5 minutes from Downtown Greenville! This is a perfect place to relax, unwind, and rejuvenate. Great for a romantic couples getaway, family vacation, or friends getting together to have fun. So cozy and picturesque. You will never want to leave! Located on-site at Saluda Outdoor Center with river tubing tours, 13 Stripes Brewery/Restaurant, live music, fishing and more (within season).

4.91 out of 5 average rating, 267 reviews

Top guest favorite

A spacious modern cabin is nestled among lush greenery, showcasing a full court for pickleball and basketball beside it. Surrounding mountains gently rise in the background, while a soft pastel sunset illuminates the serene landscape.

Cabin in Landrum

Modern Basecamp - Sauna, Pickleball, Solitude

Welcome to Mountain Modern Base Camp where you can enjoy the solitude of nature while being a short drive to limitless activities. Private 7+ acre property provides an outdoor fireplace, full court pickleball & basketball court, creek to enjoy (w/a small waterfall), firepit w/ Mtn. View’s. 30' ceilings w/large windows in the main living areas & loft. Kitchen, living areas, loft, patios & woods are set up perfectly for everyone to have their own space or be together during your stay.

5.0 out of 5 average rating, 165 reviews

Top guest favorite

A charming log cabin features a welcoming porch with a distinct wooden railing, surrounded by lush greenery. Soft lighting enhances the rustic architecture, while two gabled windows add character to the roofline. The peaceful mountain setting blends harmoniously with the natural surroundings.

Cabin in Greenville

Wooded 3BR Luxury Cabin, Close to City & Nature

Nestled atop the majestic Paris Mountain, this pet-friendly 3 bedroom 2.5 bathroom luxurious retreat promises an unforgettable experience of serenity and natural splendor. Our home stands as an oasis for those seeking an escape from the ordinary. Strategically located, it offers close proximity to Downtown Greenville and the charming Travelers Rest, ensuring guests can effortlessly blend relaxation with exploration. Here, serenity isn’t just a promise; it’s an everyday experience.

4.98 out of 5 average rating, 114 reviews

Top guest favorite

A quaint cabin is nestled among lush greenery, showcasing a rustic wooden exterior and a peaked roof. Vibrant hydrangeas bloom prominently in the foreground, complemented by a large log that enhances the natural surroundings. The backdrop features rolling hills, adding to the serene atmosphere.

Tiny home in Fletcher

Cliffside Cabin at Raven Rock Mountain

🚗 AWD/4WD required to drive to the venue 🥾 No AWD/4WD = steep uphill hike carrying all gear Our cliffside cabin is an immersion into a world where adventure meets serenity, where you'll feel the embrace of nature and the thrill of the extraordinary. Enjoy complete serenity while being just a short drive away from fantastic restaurants, shops, and attractions. ✔ Partially Suspended over a Cliff! ✔ Comfortable Queen Bed + Sofa ✔ Kitchenette ✔ Deck with Scenic Views

4.98 out of 5 average rating, 720 reviews

Top guest favorite

A wooden deck is highlighted by a fire pit at its center, surrounded by comfortable seating. Warm lighting adorns the overhead beams, casting a gentle glow over the space. The tranquil lake is visible in the background, with trees framing the scene against a dusky sky.

Home in Anderson

Sunset Point-Best view on Broadway - HOT TUB!

This gorgeous property is situated on the picturesque Broadway Lake in Anderson, SC, offering 300 acres of pristine water ideal for pontoon rides, fishing, and making unforgettable memories. This tiered lot boasts an impressive 100 feet of water frontage and a private dock, complete with four kayaks (3 single and one tandem), two paddle boards, and various floats and water fun for guests to explore the lake at their leisure.

4.97 out of 5 average rating, 170 reviews

Top guest favorite

Treehouse in Hendersonville

Treehouse at Edenwood|HotTub+Fire Pit|Pet-Friendly

A romantic treehouse near Asheville with a wood-fired hot tub The Treehouse at Edenwood is a private, design-forward escape created for couples, honeymoons, and quiet getaways in the Blue Ridge Mountains—just 12 minutes from downtown Hendersonville and close to top destinations like the Ecusta Trail, DuPont State Forest, Pisgah National Forest, the PGA Tour at Walnut Cove, the Biltmore Estate and the Blue Ridge Parkway.

5.0 out of 5 average rating, 491 reviews