
Pet-friendly vacation rentals in Upstate South Carolina
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Upstate South Carolina
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Oakey Mountain Mirror Haus
Nestled in the heart of Clarkesville, GA, Oakey Mountain Mirror Haus offers a tranquil escape where nature meets modern luxury. This cozy, thoughtfully designed tiny home is a haven for those seeking serenity. With reflective exterior walls that blend seamlessly into the lush forest surroundings, you’ll feel at one with nature while enjoying upscale amenities. Perfect for couples or solo travelers, this unique retreat invites you to unwind, recharge, and connect with the beauty of the mountains.
4.93 out of 5 average rating, 121 reviews
River View /Aframe Cabin /Goats/ Hiking Trails
South Fork River Cabin just below Watson Mill Bridge State Park, this A-Frame is a unique and tranquil escape. Perfect for a couple’s getaway, it features a king-size loft bed and peaceful river views. Adults only cabin Bring your beach towels and enjoy the chairs provided for relaxing on the sandbars and rocks in the river. In the pasture behind the cabin, our friendly goats love attention and are always happy to greet guests. We have been in a drought, so the river is very low at the moment
4.99 out of 5 average rating, 157 reviews
Private Waterfall Apt | No Shared Spaces | pets+
Our charming apartment is nestled in the woods with a prime view of your own private 15 ft waterfall in the backyard. Enjoy peace & tranquility while reading a book on the hammock or warm up by the chiminea while watching the fireflies scatter about the woods. The creek is approximately 3 ft deep at the bottom of the waterfall. The property is surrounded by State Forest. If the apartment gets rented, the rest of the house is blocked from being rented. You will not be sharing ANY space.
4.98 out of 5 average rating, 409 reviews
Starlight Chalet private hot-tub
No matter what brings you to the mountains, this cozy chalet is the perfect stay! Kitchen is lightly stocked, complete with coffee bar, spices, ceramic cookware, pans, or grill on the private patio. Relax in the hot-tub or by the fire-pit, before nestling in for a good, peaceful rest. Brevard is a short 10 min drive; unique shops, art galleries, dining. DuPont, Caesars Head, Pretty Place, Pisgah National, Gorges Parks only 10-30min. Pet-friendly, gated patio and deck. Wide, level parking area.
5.0 out of 5 average rating, 109 reviews
Napaw Mountain Log Cabin~Magical Mt.Top Experience
Welcome to Napaw Mt. Log Cabin! A pet and kid friendly, custom built cabin tucked in 35 acres of hardwoods on a private mountain top.Wrap around decks lend a lovely view of Blue Ridge Mts. Relax in the hot tub(closed Jan&Feb)by the gas fire pit or build one in the backyard fire pit or deck. Lay in the lofts king sz log bed and take in a full window view of nature.The Cabin is only mins from the best hiking, biking, shopping,fine dining in Upstate SC~Table Rock,Pretty Place,Jones Gap,Greenville
4.97 out of 5 average rating, 143 reviews
Secluded Waterfall Cabin.
Romantic, rustic cabin at the base of a 35-foot waterfall, nestled in the middle of 16 secluded acres surrounded by national forest that extends to the Chattooga River. This magical get-away caters to those with an adventurous spirit. Hike from the cabin to additional waterfalls, bike down Turkey Ridge Road to Opossum Creek Trail and the Five Falls or drive two miles to the Chattooga Belle Farm. The Waterfall Cabin is a joy to us all, and we hope you love it as much as we do. No cleaning fee.
4.99 out of 5 average rating, 401 reviews
Luxury Retreat & Heated Pool Downtown Simpsonville
Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!
4.93 out of 5 average rating, 111 reviews
TreeTop Dome@CarolinaDomes w Hot Tub near LakeLure
🌿 Luxury Glamping in the Blue Ridge Mountains! Escape to our 30-foot geodesic dome, perched on a sprawling 2000 sq ft deck surrounded by nature. Soak in your private jacuzzi under the stars, unwind in a plush queen bed, and enjoy a cozy loft with two single beds—perfect for families or friends. The dome includes a fully equipped kitchenette, BBQ grill, and all the modern comforts of home with the charm of outdoor living. Book now for a one-of-a-kind experience where peace meets adventure!
4.97 out of 5 average rating, 299 reviews
Hide Inn Seek Hillside Treehouse 1.5mi to Main St
Escape to luxury at the Hillside Treehouse brought to you by the biophilic hospitality brand 'Hide Inn Seek'. Located in Highlands NC, just 1.5 miles from main street, this newly built home sits boldly among the trees allowing you to indulge in nature while enjoying luxury accommodations. The 58 step ascent leads you up to a treehouse experience like no other. Check out our newly listed sister property, Bird Nest Treehouse, designed just for couples—complete with a full spa experience!
4.97 out of 5 average rating, 174 reviews
New! Riverfront Tiny Home - Downtown Greenville SC
The River House is a boutique tiny home on the river front of the Saluda with breathtaking views - just 5 minutes from Downtown Greenville! This is a perfect place to relax, unwind, and rejuvenate. Great for a romantic couples getaway, family vacation, or friends getting together to have fun. So cozy and picturesque. You will never want to leave! Located on-site at Saluda Outdoor Center with river tubing tours, 13 Stripes Brewery/Restaurant, live music, fishing and more (within season).
4.91 out of 5 average rating, 267 reviews
Cliffside Cabin at Raven Rock Mountain
🚗 AWD/4WD required to drive to the venue 🥾 No AWD/4WD = steep uphill hike carrying all gear Our cliffside cabin is an immersion into a world where adventure meets serenity, where you'll feel the embrace of nature and the thrill of the extraordinary. Enjoy complete serenity while being just a short drive away from fantastic restaurants, shops, and attractions. ✔ Partially Suspended over a Cliff! ✔ Comfortable Queen Bed + Sofa ✔ Kitchenette ✔ Deck with Scenic Views
4.98 out of 5 average rating, 724 reviews
Cozy Off-Grid Luxury Cabin w/ River Access.
*PLEASE READ EVERYTHING BEFORE BOOKING* The PineStone @ StayCamp is an off-grid tiny cabin in the middle of nature. Situated on 44 acres of lush rolling forest with flowing creeks and a small waterfall. Just 10 minutes away from the blooming downtown of Spartanburg, SC. Close to everything, but feels as if you are a world away from anything. Hike along the trails, take a nap in the kingsized bed, or relax in a 70sqft hammock.
4.98 out of 5 average rating, 105 reviewsPopular amenities for Upstate South Carolina pet-friendly home rentals
Pet-friendly house rentals

Luxury 4BR in Historic District, Walk to Downtown
4.99 out of 5 average rating, 139 reviews
Clemson Lake Hartwell Waterfront, Pontoon Rental
4.95 out of 5 average rating, 148 reviews
Modern Wooded Retreat
5.0 out of 5 average rating, 185 reviews
Lake Escape
4.99 out of 5 average rating, 224 reviews
Pettigru House: Historic Boutique Stay, Greenville
5.0 out of 5 average rating, 110 reviews
Sunset Point-Best view on Broadway - HOT TUB!
4.97 out of 5 average rating, 171 reviews
Park Cottage at State Park -15min Dwtn GVL, Furman
4.97 out of 5 average rating, 219 reviews
Perfect 2 bed, remodeled home in quaint Pendleton
5.0 out of 5 average rating, 282 reviewsPet-friendly home rentals with a pool

Cabin in the woods
4.98 out of 5 average rating, 483 reviews
Pool Open Through Sept Perfect End-of-Summer Fun
4.96 out of 5 average rating, 270 reviews
Stylish Hotel Room in the Heart of Greenville
4.8 out of 5 average rating, 139 reviews
Beautiful Lake Keowee Condo with great Amenities
4.96 out of 5 average rating, 165 reviews
Wooded Cottage/Hot tub/Gameroom/Firepit/pets ok
4.83 out of 5 average rating, 112 reviews
Renfrow's Retreat
4.96 out of 5 average rating, 195 reviews
Pool, King, Fireplace, Lakefront, Kayaks, Firepit
4.99 out of 5 average rating, 103 reviews
College View Cottage & Saltwater Pool
4.99 out of 5 average rating, 294 reviewsPrivate, pet-friendly home rentals

The Cottage at Old Oaks Farm
4.99 out of 5 average rating, 468 reviews
Peaceful Lake Cabin - Close to Town - sleeps 6
4.92 out of 5 average rating, 198 reviews
West End Nest | Steps to Falls Park & Main
4.98 out of 5 average rating, 323 reviews
Private Luxury Glamping Dome | Hot Tub & Views
4.99 out of 5 average rating, 308 reviews
Modern Basecamp - Sauna, Pickleball, Solitude
5.0 out of 5 average rating, 167 reviews
The Cottage at Flourish Farm - 6 mins to Erskine
4.99 out of 5 average rating, 220 reviews
Log Haven at Travelers Rest
4.98 out of 5 average rating, 284 reviews
Sunset Mtn Views • Hot Tub • 7 Min to Bryson City
4.99 out of 5 average rating, 138 reviewsDestinations to explore
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- Clemson University
- Blue Ridge Parkway
- Tryon International Equestrian Center
- Table Rock State Park
- The North Carolina Arboretum
- Chimney Rock State Park
- Gorges State Park
- Devils Fork State Park
- Lake Lure Beach and Water Park
- DuPont State Forest
- Bon Secours Wellness Arena
- Saint Paul Mountain Vineyards
- Jump Off Rock
- Fred W Symmes Chapel
- Falls Park On The Reedy
- Jones Gap State Park
- Fluor Field at the West End
- Peace Center
- Whitewater Falls
- Carl Sandburg Home National Historic Site
- Overmountain Vineyards
- Oconee State Park
- Furman University
- Memorial Stadium, Clemson
- Things to do Upstate South Carolina
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- Cooking South Carolina
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