Pet-friendly vacation rentals in Upstate South Carolina

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Upstate South Carolina

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Guest favorite
An aerial view of the modern cabin, surrounded by vibrant fall foliage. The expansive deck features a hot tub and various seating areas, with a stunning landscape of trees and mountains in the background, demonstrating a seamless connection to nature.
Shipping container in Clarkesville
4.94 out of 5 average rating, 117 reviews

Oakey Mountain Mirror Haus

Nestled in the heart of Clarkesville, GA, Oakey Mountain Mirror Haus offers a tranquil escape where nature meets modern luxury. This cozy, thoughtfully designed tiny home is a haven for those seeking serenity. With reflective exterior walls that blend seamlessly into the lush forest surroundings, you’ll feel at one with nature while enjoying upscale amenities. Perfect for couples or solo travelers, this unique retreat invites you to unwind, recharge, and connect with the beauty of the mountains.

Top guest favorite
The A-frame cabin is situated among tall trees, showcasing natural wood elements and a sloped roof. A welcoming deck is visible at the front, surrounded by well-maintained paths and rustic landscaping, inviting guests to explore the serene woodland setting.
Cabin in Carlton
4.99 out of 5 average rating, 155 reviews

PrivateRiverView/AframeCabin/Goats/Fishing/Trails

South Fork River Cabin just below Watson Mill Bridge State Park, this A-Frame is a unique and tranquil escape. Perfect for a couple’s getaway, it features a king-size loft bed and peaceful river views. Adults only cabin Bring your beach towels and enjoy the chairs provided for relaxing on the sandbars and rocks in the river. In the pasture behind the cabin, our friendly goats love attention and are always happy to greet guests. We have been in a drought, so the river is very low at the moment

Top guest favorite
A custom log cabin with a spacious deck is nestled among tall hardwood trees. Sunlight filters through the foliage, highlighting the natural wood exterior and stone chimney. Surrounding greenery provides a serene forest setting, emphasizing the cabin's private and tranquil location.
Cabin in Marietta
4.96 out of 5 average rating, 141 reviews

Napaw Mountain Log Cabin~Magical Mt.Top Experience

Welcome to Napaw Mt. Log Cabin! A pet and kid friendly, custom built cabin tucked in 35 acres of hardwoods on a private mountain top.Wrap around decks lend a lovely view of Blue Ridge Mts. Relax in the hot tub(not open Jan/Feb)by the gas fire pit or build a fire in the fireplace on the deck. Lay in the lofts king sz log bed and take in a full window view of nature.The Cabin is only mins from the best hiking, biking, shopping,fine dining in Upstate SC~Table Rock,Pretty Place,Jones Gap,Greenville

Superhost
A vibrant scene showcases two golden retrievers playing in a shallow stream, surrounded by lush green foliage. Behind them, a cascading waterfall flows over rocky tiers, creating a soothing sound and enhancing the natural beauty of the forested landscape.
Cabin in Oconee County
4.99 out of 5 average rating, 397 reviews

Secluded Waterfall Cabin.

Romantic, rustic cabin at the base of a 35-foot waterfall, nestled in the middle of 16 secluded acres surrounded by national forest that extends to the Chattooga River. This magical get-away caters to those with an adventurous spirit. Hike from the cabin to additional waterfalls, bike down Turkey Ridge Road to Opossum Creek Trail and the Five Falls or drive two miles to the Chattooga Belle Farm. The Waterfall Cabin is a joy to us all, and we hope you love it as much as we do. No cleaning fee.

Guest favorite
The outdoor area showcases a tranquil pool surrounded by lush greenery, with comfortable lounge chairs positioned nearby. A pastel sunset provides a serene backdrop, while inflatable pool accessories add a playful touch to the inviting atmosphere.
Home in Simpsonville
4.93 out of 5 average rating, 106 reviews

Luxury Retreat & Heated Pool Downtown Simpsonville

Luxury Pool House in the Heart of Simpsonville – Perfect for Gatherings! Designed for comfort, fun, and relaxation. 2 minutes from Downtown Simpsonville and 15 minutes from Downtown Greenville, this luxury retreat feels like a private resort with all the warmth of home. With nature views and countless amenities, you’ll have everything you need for an unforgettable stay. Up to 8 guests with 4 Spacious Beds and 2.5 Baths. Indoor & Outdoor Entertainment, Well-Equipped Kitchen, Cozy Living Room!

Top guest favorite
A fire pit surrounded by rustic wooden seating is illuminated by a warm glow from the flames. In the background, a geodesic dome is nestled among trees on a raised deck, creating a serene outdoor ambiance.
Dome in Union Mills
4.98 out of 5 average rating, 291 reviews

TreeTop Dome@CarolinaDomes w Hot Tub near LakeLure

🌿 Luxury Glamping in the Blue Ridge Mountains! Escape to our 30-foot geodesic dome, perched on a sprawling 2000 sq ft deck surrounded by nature. Soak in your private jacuzzi under the stars, unwind in a plush queen bed, and enjoy a cozy loft with two single beds—perfect for families or friends. The dome includes a fully equipped kitchenette, BBQ grill, and all the modern comforts of home with the charm of outdoor living. Book now for a one-of-a-kind experience where peace meets adventure!

Guest favorite
A modern living room features a spacious green couch and colorful accent chairs, with natural light illuminating the area. The exterior showcases a contemporary structure with large windows surrounded by trees. A game room offers a pool table, while the outdoor area includes a movie screen.
Home in Greenville
4.95 out of 5 average rating, 105 reviews

Riverfront-10 min Dwtn Gvl-HotTub-GameRm-Sleeps 13

Greenville's riverfront- Sleeps 13 on the Saluda River! This riverfront escape is 10 min to downtown Greenville, 30 min to Clemson, and packed with fun! Enjoy 2 master suites, a bunk room, game room (pool table, arcade, karaoke), hot tub, Sauna, cold plunge firepit, outdoor kitchen, movie screen, kayaks, and more. Close to Falls Park, PKL Pickleball, Paris Mountain & dining. Perfect for families, groups & game-day stays. Launch kayaks right from your home. Book now for the ultimate getaway!

Top guest favorite
An aerial view of a spacious two-level brick home is presented, showcasing a large parking area in front with two garage doors visible. Surrounding greenery enhances the setting, while the property is bordered by trees, providing a sense of privacy.
Home in Anderson
4.94 out of 5 average rating, 145 reviews

Clemson Lake Hartwell Waterfront, Pontoon Rental

Come and enjoy a relaxing family vacation on beautiful Lake Hartwell in this spacious 2 level home. Plenty of room for multiple families to share. This 7600 sq. ft lakefront home sleep up to 18 featuring 7 bedrooms with 1 additional rooms with sofa beds; 5 full-sized bathrooms; 1 laundry area with 2 washers & 2 dryers. Each level boasts a fully furnished kitchen along with a large entertainment area. Breakfast area off main kitchen in addition to a spacious dining room that seats up to 10.

Top guest favorite
The exterior of the treehouse is showcased in twilight, highlighting a spacious deck with multiple seating areas. Lanterns illuminate the wood accents of the house, and large windows reflect the surrounding greenery. A dining table is arranged on the deck, set for enjoyable outdoor meals.
Treehouse in Highlands
4.97 out of 5 average rating, 172 reviews

Hide Inn Seek Hillside Treehouse 1.5mi to Main St

Escape to luxury at the Hillside Treehouse brought to you by the biophilic hospitality brand 'Hide Inn Seek'. Located in Highlands NC, just 1.5 miles from main street, this newly built home sits boldly among the trees allowing you to indulge in nature while enjoying luxury accommodations. The 58 step ascent leads you up to a treehouse experience like no other. Check out our newly listed sister property, Bird Nest Treehouse, designed just for couples—complete with a full spa experience!

Guest favorite
A spacious outdoor living area features a comfy sectional sofa and a wooden coffee table, surrounded by lush greenery. Two hanging chairs provide a relaxing spot to enjoy the expansive mountain views, while a hammock stretches across the deck, inviting tranquil moments.
Home in Highlands
4.92 out of 5 average rating, 107 reviews

Huge Views, Outdoor Tub, Fire Pit, Close to Town!

Perched at 4,200' high and under 10 minutes to downtown Highlands and Cashiers, this easily accessed, light filled, cabin offers massive, year-round, long range views of Whiteside &Rock Mountains from every room of the house as well as from our expansive decks! -10 Minutes to Downtown Highlands (shopping, dining, art culture) -8 Minutes to Cashiers Crossroads (Whiteside brewery, coffee, shopping) -5 Minutes to Whiteside Mountain trailhead -15 Minutes to Lake Glenville (Boat Rentals!)

Guest favorite
A deck area overlooking the river features wooden railings with metal accents. Several outdoor chairs are positioned on the deck, while the river flows gently beside it. Lush trees line the riverbank, providing a natural backdrop.
Tiny home in Easley
4.91 out of 5 average rating, 267 reviews

New! Riverfront Tiny Home - Downtown Greenville SC

The River House is a boutique tiny home on the river front of the Saluda with breathtaking views - just 5 minutes from Downtown Greenville! This is a perfect place to relax, unwind, and rejuvenate. Great for a romantic couples getaway, family vacation, or friends getting together to have fun. So cozy and picturesque. You will never want to leave! Located on-site at Saluda Outdoor Center with river tubing tours, 13 Stripes Brewery/Restaurant, live music, fishing and more (within season).

Top guest favorite
A charming log cabin features a welcoming porch with a distinct wooden railing, surrounded by lush greenery. Soft lighting enhances the rustic architecture, while two gabled windows add character to the roofline. The peaceful mountain setting blends harmoniously with the natural surroundings.
Cabin in Greenville
4.98 out of 5 average rating, 113 reviews

Wooded 3BR Luxury Cabin, Close to City & Nature

Nestled atop the majestic Paris Mountain, this pet-friendly 3 bedroom 2.5 bathroom luxurious retreat promises an unforgettable experience of serenity and natural splendor. Our home stands as an oasis for those seeking an escape from the ordinary. Strategically located, it offers close proximity to Downtown Greenville and the charming Travelers Rest, ensuring guests can effortlessly blend relaxation with exploration. Here, serenity isn’t just a promise; it’s an everyday experience.

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