Vacation rentals with lake access in Upstate South Carolina

Find and book unique lake access rentals on Airbnb

Top-rated lake access rentals in Upstate South Carolina

Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

The entrance features large, rustic double doors opening to reveal a stylishly decorated bedroom. A crystal chandelier hangs above a beautifully crafted bed with an intricate headboard. Two decorative topiary plants frame the doorway, adding a touch of greenery to the warm wooden floor.

Treehouse in Waterloo

#1 most loved AirBnB in SC! *Old Soul Treehouse*

The Old Soul Treehouse is a fabulous destination for couples looking to have a unique getaway! A waterfront treehouse on Lake Greenwood w/ a private dock, heat/AC, hot tub, king size bed, & a fully equipped kitchen & bathroom. Take a dip in the lake during the day or at night enjoy a soak in the hot tub on the peaceful porch under the stars. Whether you're celebrating a special occasion or simply taking time to reconnect, we hope you book with us for an intimate experience with the one you love!

ViewOutdoor spacesKitchen

4.99 out of 5 average rating, 262 reviews

Top guest favorite

A serene lake view is captured at sunset, featuring a dock and pavilion extending into the water. Lush grasses and landscaped stones frame the scene, as warm sunlight bathes the area in golden tones, enhancing the tranquil atmosphere of the shoreline.

Cottage in Six Mile

Lake Keowee Waterfront Cottage - Private Retreat

Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

NearbyOutdoor spacesAccess

4.99 out of 5 average rating, 211 reviews

Top guest favorite

A spacious living area is defined by high ceilings and warm pine paneling. A large stone fireplace serves as a central feature, with comfortable seating arranged around a wooden table. Bright windows allow ample natural light, and a decorative chandelier hangs above.

Cabin in Highlands

Peaceful Lake Cabin - Close to Town - sleeps 6

Enjoy a peaceful cabin getaway on Apple Lake, 5 minutes from Highlands, NC. Highlands is a charming mountain town with great restaurants, spa, theater, music concerts, and shopping. Our cabin is very open with high ceilings, a huge wood burning fire place, two bedrooms downstairs, and two upstairs in an open loft. Minutes from scenic waterfalls, and hiking trails. Enjoy relaxing on the porch, cooking, fishing, and kayaking on the lake. Wonderful for family/friend vacations or a romantic getaway!

ViewNearbyIndoor spaces

4.92 out of 5 average rating, 198 reviews

Top guest favorite

A private pool is surrounded by a wooden deck, with stylish lounge chairs positioned nearby. The serene view overlooks Lake Greenwood, complemented by a colorful sunset reflecting on the water's surface. Lush greenery frames the scene, creating a peaceful atmosphere.

Cottage in Greenwood

Pool, King, Fireplace, Lakefront, Kayaks, Firepit

Welcome to our charming 3 bedroom, 2 bathroom house located on Lake Greenwood in South Carolina—perfect for families or couples looking for a fun-filled vacation or relaxing break. Lake access is right on our property, so you can easily swim, fish, boat, paddle using provided kayaks, or just enjoy the picturesque view. Additionally, our home features a private pool (May through Sep). End your evening relaxing around our fire pit roasting marshmallows, or sit on the deck overlooking the lake.

Outdoor spacesViewBathroom

4.99 out of 5 average rating, 103 reviews

Top guest favorite

A charming log cabin is reflected in the calm waters of a pond, surrounded by lush trees. Bright red chairs are positioned near the water's edge, with a small blue boat visible nearby. The setting provides a serene and natural atmosphere.

Cabin in Travelers Rest

Log Haven at Travelers Rest

Take to the Woods and discover a private, peaceful “Hallmark card” cabin overlooking a 2 acre stream fed pond (plenty of Large Mouth Bass & Sun fish) alongside 12 acres of Pine & hardwood forest with paths, kayaks and peddle boat for your enjoyment. Lounge on the wide wrap around porch, al fresco dining, hammock naps, grilling, campfires. A magical getaway yet close to the super cute town Travelers Rest, Swamp Rabbit Trail and Furman U. Cleaned professionally; Owner managed and live on site.

NearbyOutdoor spacesSleep quality

4.98 out of 5 average rating, 284 reviews

Top guest favorite

A spacious covered patio area features modern outdoor seating, with a view of the lake framed by large glass doors. Soft string lights hang overhead, enhancing the serene atmosphere. A cozy fire pit table offers an inviting focal point for gatherings.

Home in Easley

Luxurious 3BR on Lake Saluda w/ Kayaks, Fire Pit

Welcome to Lake Saluda Serenity, your tranquil lake house retreat just 15 minutes from Downtown Greenville! This stylish 3BR, 2BA haven combines modern aesthetics with breathtaking natural views. Revel in tranquility on the spacious patio or delve into adventures with provided kayaks and pedal boats. Explore lake life at your pace and soak in the serene surroundings. Nestled in an idyllic locale with top-notch amenities, it's your quintessential escape to lakefront luxury and modern comfort.

Outdoor spacesViewCheck-in

4.99 out of 5 average rating, 107 reviews

Guest favorite

Home in Six Mile

House on Lake Keowee swim beach in cove w/ Dock

This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.

Outdoor spacesNearbyIndoor spaces

4.84 out of 5 average rating, 283 reviews

Top guest favorite

An aerial view of a spacious two-level brick home is presented, showcasing a large parking area in front with two garage doors visible. Surrounding greenery enhances the setting, while the property is bordered by trees, providing a sense of privacy.

Home in Anderson

Clemson Lake Hartwell Waterfront, Pontoon Rental

Come and enjoy a relaxing family vacation on beautiful Lake Hartwell in this spacious 2 level home. Plenty of room for multiple families to share. This 7600 sq. ft lakefront home sleep up to 18 featuring 7 bedrooms with 1 additional rooms with sofa beds; 5 full-sized bathrooms; 1 laundry area with 2 washers & 2 dryers. Each level boasts a fully furnished kitchen along with a large entertainment area. Breakfast area off main kitchen in addition to a spacious dining room that seats up to 10.

ViewNearbyWalkability

4.95 out of 5 average rating, 148 reviews

Guest favorite

An outdoor game area features a pool table, with a set of colorful balls arranged on the surface. The scene includes a grassy lawn leading to the water, where a sunset illuminates the landscape. Two red chairs and a picnic-style setup are visible nearby.

Home in Prosperity

Sunset Cove-Beautiful Lake views

Your home away from home on Lake Murray! Spacious, modern clean, home with 3 levels of living -3 spacious decks, screen porch, and sunroom all with massive lake views! Plenty to do at Sunset Cove relaxing with family and friends and toys galore! "Wow just wow, best Airbnb ever..Sarah, June 2026. "..clean, beautiful view and so many fun games..Lisa, Oct 2025."Perfect setting for a quiet getaway. The house was amazing, clean, and had all the amenities we were looking for.."Jay, Sept 2025

Outdoor spacesViewGrill

4.91 out of 5 average rating, 107 reviews

Top guest favorite

Cabin in Tamassee

A Lakefront Tiny Cabin • Hot Tub • Kayaks • Canoe

Whitewater Cabin is where you wake up to peaceful lake views, sip coffee on the porch, and spend the day kayaking or swimming from your private dock. This lakefront cabin is tucked away on a private Lake in the South Carolina mountains, minutes from Lake Jocassee and Lake Keowee. It’s the perfect getaway for couples, families, or friends looking to escape into nature. After a day exploring waterfalls, hiking, or boating, come back and unwind in the hot tub overlooking the water.

NearbyViewHospitality

4.97 out of 5 average rating, 187 reviews

Top guest favorite

A modern cottage features a spacious covered porch with string lights, surrounded by a lush green lawn. Large glass doors invite natural light into the interior, while tall trees provide shade in the background against a colorful sunset sky.

Cottage in Anderson

Lakefront dock *hot tub* Anderson/Clemson king bed

Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

Outdoor spacesViewCheck-in

4.97 out of 5 average rating, 266 reviews

Top guest favorite

A wooden deck is highlighted by a fire pit at its center, surrounded by comfortable seating. Warm lighting adorns the overhead beams, casting a gentle glow over the space. The tranquil lake is visible in the background, with trees framing the scene against a dusky sky.

Home in Anderson

Sunset Point-Best view on Broadway - HOT TUB!

This gorgeous property is situated on the picturesque Broadway Lake in Anderson, SC, offering 300 acres of pristine water ideal for pontoon rides, fishing, and making unforgettable memories. This tiered lot boasts an impressive 100 feet of water frontage and a private dock, complete with four kayaks (3 single and one tandem), two paddle boards, and various floats and water fun for guests to explore the lake at their leisure.

Outdoor spacesNearbyCheck-in

4.97 out of 5 average rating, 171 reviews