Vacation rentals with lake access in Upstate South Carolina

Find and book unique lake access rentals on Airbnb

Top-rated lake access rentals in Upstate South Carolina

Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

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Guest favorite

Cottage in Lyman

4.99 out of 5 average rating, 233 reviews

Lakeside Retreat

With quiet views on Lyman Lake in South Carolina, this cottage is a great place to rest and relax. Close to Greenville and Spartanburg, SC. You’ll love my place because of the location, the ambiance, and the outdoor space. My place is good for couples, solo adventurers, and business travelers. GSP Airport-7 miles, Peace Center/Downtown Greenville-15 miles, Downtown Spartanburg-15 miles, Clemson Univ-42 miles, Furman Univ-14 miles, Tryon- 14 miles, Charlotte Airport-73 miles Asheville-46 mi

Oct 4 – 11

G$25,648 GYD per night

Guest favorite

Guesthouse in Abbeville

4.97 out of 5 average rating, 286 reviews

Quiet, Peaceful Loft in the Woods

Come relax for a getaway in our elegant guest loft! Located near the end of a quiet road with lots of wide open fields and beautiful tree lines! Our loft features a cute kitchenette, plenty of closet space, TV(YoutubeTV & Roku), an extremely comfortable bed! The loft is kept very clean and neat and will be stocked with all the essentials. Access to a beautiful 33' above ground pool! We are conveniently located about 5 miles from downtown Abbeville, and only a 10 minute drive to Erskine/Due West!

Aug 3 – 10

G$13,679 GYD per night

Guest favorite

Guesthouse in Anderson

5.0 out of 5 average rating, 218 reviews

Game Day Cottage in the Woods

Great location just off of I-85 at Exit 14; less than 8 miles to Clemson University, 7 miles to Green Pond Landing, and 1000 feet to Eighteen Mile Creek Boat Landing. Our cottage is located behind our home with a beautiful wooded setting. You will find a tranquil and secluded space, yet be close enough to our areas best restaurants and entertainment. We are also close enough to the Blue Ridge Mountain for a nice day trip. Please note our rate is $240 per night during Clemson home games.

Aug 8 – 15

G$24,642 GYD per night

Guest favorite

Tiny home in Greer

4.93 out of 5 average rating, 134 reviews

Shalom Tiny with Lake View - Greer, SC

Find Shalom, stay in our tiny home :) Reconnect with nature at this unforgettable escape on Lake Cunningham in Greer, SC. We are conveniently located by: - Historic Downtown Greer SC (drive: 10 min) - 23 minutes to Downtown Greenville - GSP airport (17 min) - Many parks & restaurants (5-15 min) You'll enjoy private access, comfy queen bed, ample living area, bathroom (w/ shower), WIFI & lake access. We have a kitchen ready for your cooking needs and a dedicated work space for remote workers.

Jan 19 – 26

G$24,029 GYD per night

Guest favorite

Home in Iva

4.98 out of 5 average rating, 156 reviews

Moonshine Bay

Your home away from home on South Carolina’s hidden gem, Lake Secession. Private wooded drive opens up to phenomenal lake view with shallow water entrance. Great for water sports, swimming, fishing and relaxation. If swimming isn’t for you, many beautiful reasonably priced golf courses are near by. Only 10 miles from Anderson & 36 miles to Clemson Stadium. Pull your boat to the dock or just enjoy some of our non-motorized lake toys. You’ll love it so much you want to come back year after year!

Mar 22 – 29

G$33,838 GYD per night

Guest favorite

Guesthouse in Greenwood

4.94 out of 5 average rating, 181 reviews

Private Lakefront Cabin on Lake Greenwood

Get ready to enjoy beautiful lake views from this home! Private lake house right on Lake Greenwood. This recently remodeled guest house has one bedroom with a queen bed, full bath, and a large main room with a huge sectional sofa. Strong WIFI. 50" tv: Roku/Netflix/Hulu equipped. Enjoy 128ft of lakeshore including a fire pit, concrete pier, pergola seating area, beach, swimming area in lake, and putting green. 2 Kayaks available, free to use. 20ft pontoon for rent based on availability.

Jun 23 – 28

G$35,773 GYD per night

Guest favorite

Guest suite in Greenville

5.0 out of 5 average rating, 167 reviews

Cozy, Cute & Clean Cottage on Saluda Lake

Stunning lake views from private covered deck with daily western sunsets. Large dock to sit, sun, read or fish. Two kayaks with life vests available to tour the water. Saluda Lake is said to be one of Greenville's best kept secrets. Though a small 331 acre lake, the nearly 2 mile river to the 1920's working dam is great water to boat and fish. 13 mins to main street Greenville; 5 mins to Furman University; 45 mins to Clemson University or Lake Hartwell area. 5 mins to grocery stores.

Sep 5 – 12

G$26,267 GYD per night

Guest favorite

Farm stay in Fountain Inn

4.94 out of 5 average rating, 139 reviews

The Fountain Moon Cabin on Hidden Pasture Farm

Such a unique property, do not miss this special place. We have so much to offer nature and animal lovers. Quiet and peaceful, The Fountain Moon Cabin at Hidden Pasture Unicorn Farm® is a breathtaking getaway to relax and enjoy nature or some good old fashioned gettin' back to center, your center. We are nestled on small pond with dock, canoe and paddle boat, plus fishing. We have trails and a wonderful agritourism visiting area and are the only visiting Unicorn Farm® in the world.

Oct 8 – 15

G$24,659 GYD per night

Guest favorite

Home in Easley

4.9 out of 5 average rating, 276 reviews

“Lake House Paradise” Waterfront Oasis

“Lake Paradise” is exquisitely furnished with 2 bedrooms and 1 and a half baths. Your Master Suite has its own screened in porch with private lake access. Wake up from your master suite to views from your bed of the water. Your en suite Master Bathroom has a large luxury marble shower. You will spend many hours of relaxation and peace in the most desirable location in the southeast. Visit Greenville SC's downtown just 15 minutes away. Clemson football Stadium is 20 miles away.

Jan 18 – 25

G$29,415 GYD per night

Guest favorite

Shipping container in Easley

4.99 out of 5 average rating, 189 reviews

Luxury lakefront container home + private dock

Start your next adventure at The Hive at Addison Farms! Upon arrival, you will be greeted with an incredible, picturesque view of Saluda Lake. This carefully designed romantic retreat is the ultimate getaway to unwind, reconnect, and relax. The Hive is conveniently located less than 20 mins. from Downtown Greenville, making it the perfect destination for a secluded weekend away, yet close enough to explore the wonderful places and activities in Upstate, SC.

Aug 20 – 27

G$75,094 GYD per night

Guest favorite

Farm stay in Easley

4.99 out of 5 average rating, 189 reviews

Dogwood Cottage- farm charm - Greenville & Clemson

A retreat in and of itself! This perfect, peaceful cottage is complete with full kitchen, bath and private porch. This converted llama barn elevates reclaimed woods and metals into a darling spot on our 24 acre farm. Serene and tranquil yet only minutes from downtown Greenville or Clemson activities. Nature galore with walking, fishing and even farm animals to meet. Our farm sits at the foot of the Blue Ridge with many quaint mountain towns to visit.

Jan 17 – 24

G$21,941 GYD per night

Guest favorite

Guest suite in Greenville

4.9 out of 5 average rating, 221 reviews

modern lux lakefront suite, 6mi dt GVL

PRIVATE DOCK + LAKEFRONT + JET SKI RENTAL + 6 MILES TO DOWNTOWN GREENVILLE! NY Times #1 AMERICAN CITY! Experience luxury in your serene private suite **located in modern scandinavian-style chalet on Saluda Lake** 6mi downtown Greenville, 5mi Traveler’s Rest, 4mi Furman, 4mi Paris Mtn - Private dock / jet ski paddleboard rental - Private entrance flower-friendly patio - 43” Roku TV - Charcoal grill, fire pit - Blackout blinds

Mar 16 – 23

G$20,979 GYD per night