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Mansion vacation rentals in Panama

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Popular amenities for Panama mansion rentals

Luxury mansion rentals

Guest favorite
Villa in Bocas del Toro
5 out of 5 average rating, 64 reviews

Casa del Mar - eco aqua villa

EsterRating, 5 stars1 month ago
Julia’s place is an absolute gem, nestled in the calm waters of the Caribbean Sea at the southern tip of Isla Cristóbal—about a 30-minute boat ride from the main island, Isla Colón. From the moment we arrived, we felt like we were stepping into a unique off-grid paradise. The house itself is self-sustaining, powered by solar energy and using filtered rainwater (which, by the way, tastes amazing!). While there’s no air conditioning, there are plenty of fans to keep the air moving. The views from the house are absolutely stunning. In the mornings, dolphins often patrol the area like local marine police, and right beneath the house, we saw massive snappers swimming in the clear waters. If you paddle out into deeper water by kayak or paddleboard, you’ll likely spot graceful rays gliding beneath you—an unforgettable experience. Victoriano, a local caretaker, was extremely helpful on the property and in surrounding areas and guided us on a hike to see the sloths and the monkeys.
Guest favorite
A lakeside gazebo with a tiled roof is situated among lush greenery. Kayaks in vibrant colors await on a wooden dock extending over the water. Comfortable seating is arranged on the platform, providing a serene space for relaxation by the lake.
Cottage in Panama City
5 out of 5 average rating, 19 reviews

Hacienda La Perezosa en Cerro Azul

TeddyRating, 5 stars1 month ago
Very well maintained and clean. Perfect spot for a relaxing time with ample amenities and service staff. Will definitely repeat!
Superhost
Villa in Saboga
4.75 out of 5 average rating, 12 reviews

Casa Laguna - luxury beach front house with pool

PhilippRating, 5 stars5 months ago
Das Haus ist idyllisch direkt am Strand gelegen und sehr gut ausgestattet (gilt für alle Bereiche). Zwei Schlafzimmer sind riesig und haben das Niveau einer gehobenen Hochzeitsreise. Die zwei anderen Schlafzimmer sind auch sehr schön, aber kleiner. Es gibt u.a. einen grosses, schönes Wohnzimmer mit Blick auf Pool, Whirlpool und Strand mit Meer. Wir waren dort mit 5 Erwachsenen und 2 Kindern und haben uns rundum sehr wohl gefühlt. Der Eigentümer Matthias war sehr freundlich im Vorhinein (war selbst nicht vor Ort) und vor Ort hat sich Patrice, der seit langem auf der Insel lebt (und u.a. perfekt Englisch spricht) sich swhr freundlich und hervorragend um alles Logistische (Fahrt von der Fähre zum Haus und zurück und Erkundungsfahrten auf der Insel, Bootsfahrten auf Nachbarinseln) gekümmert. Suli und Jonathan (sprechen nur spanisch) waren vor Ort und haben sich sehr zuvorkommend um die alltäglichen Bedürfnisse gekümmert (Einkäufe, Fragen zur Unterkunft). Ein von einem Franzosen betrie
Top guest favorite
A balcony setting features a circular table surrounded by four chairs, overlooking a scenic view of the ocean. A grill is positioned nearby, and expansive glass doors provide indoor access, enhancing the outdoor dining experience.
Condo in Maria Chiquita
5 out of 5 average rating, 39 reviews

Playa Escondida. Apartamento con vista al mar.

RoderickRating, 5 stars2 weeks ago
Todo perfecto, el apartamento muy bonito, Vanessa muy atenta, no hay quejas, recomendamos full !
Guest favorite
Two spacious lounge chairs are positioned beside a serene pool, reflecting the surrounding palm trees and soft morning light. Umbrellas provide shade over seating areas, while distant ocean waves can be seen beyond the elegantly landscaped grounds.
Villa in Rio Hato
4.92 out of 5 average rating, 59 reviews

Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

MelissaRating, 5 stars2 days ago
Everything was perfect! This home exceeded our expectations. The kitchen was extremely well stocked and there were extra linens, pool toys, and everything we could have wanted. The home and area are stunning. Host was very helpful and responsive. We highly recommend staying here!
Top guest favorite
Home in Rio Hato
4.95 out of 5 average rating, 37 reviews

Villa Santorini | Playa Blanca

VirginiaRating, 5 stars1 week ago
La casa acogedora, perfecta para grupo de amigos con sus familias, cada habitación tiene su baño y por ende todos tuvimos bastante privacidad. Las áreas comunes espaciosas ideal para los niños, con todas las comodidades, la playa super cerca... Volveríamos a ir
Top guest favorite
A comfortable media room features plush leather seating equipped with built-in cup holders. A large screen is positioned on the opposite wall, surrounded by soft lighting. Natural light enters through expansive windows, offering views of greenery outside, enhancing the inviting atmosphere.
Villa in Panamá
4.98 out of 5 average rating, 53 reviews

Breathtaking Views Mansion w/King Beds

PavanRating, 5 stars4 weeks ago
Its a 5 star house. The house is way bigger than what photos suggest. It can easily fit in 10 people. It is in a very safe neighborhood and close to great restaurants and bakery. It also has good India mart close by if you need any Indian provisions. House all the amenities you need. Pool, garage, big grill, nice kitchen, theatre room with pool table and a yoga place. The only part of the house that we could not get to enjoy is the golf area. I wish we had more time at the house. Will definitely recommend the house. Also Bradley was very responsive.
Guest favorite
The modern architectural home is viewed from the water at night, illuminated by warm lights from within. Reflections shimmer across the calm surface of the water, while the surrounding trees are softly silhouetted against the night sky.
Home in Bocas del Toro
4.92 out of 5 average rating, 25 reviews

Architectural Waterfront Home- "Casa Comunal"

FrankRating, 5 stars4 months ago
Fantastische plek, de zee is je achtertuin. Apen, volgels, eekhoorns en op de golven voorbij komende surfers. Geweldig huis, minimalistisch maar heel leuk mit diverse hangplekken. Hou er wel rekening mee dat het warm kan zijn in het huis en dat er insecten makkelijk binnen kunnen komen....maar daar staat iets geweldigs tegenover.

Pet-friendly mansion rentals

Top guest favorite
The outdoor area features a large swimming pool surrounded by lounge chairs, with a separate jacuzzi nearby. Inside, a game room comprises a pool table and a ping pong table, with expansive glass doors allowing natural light and views of the greenery.
Villa in Costa Esmeralda
4.97 out of 5 average rating, 95 reviews

#1 Villa con piscina, jacuzzi, billar, pin pon.

MarubyRating, 5 stars1 month ago
La verdad excelente la casa, siempre estuvieron pendientes de que estuviéramos cómodo. Todo limpio, lo recomiendo. Fue un fin de semana maravilloso.
Guest favorite
A spacious house is surrounded by lush greenery, featuring a large private swimming pool that reflects the clear sky. Outdoor seating areas are visible, including a sunlit terrace adorned with a hammock, and a trampoline can be seen in the nearby yard.
Villa in San José
4.83 out of 5 average rating, 72 reviews

25% OFF The Family Mini Resort House @Punta Barco

ErikaRating, 5 stars3 weeks ago
Súper bueno el lugar , solo que faltaron algunos detalles, no funcionaba 1 aire y la luces de los baños varias estaban quemadas , pero por lo demás todo bien
Guest favorite
An inviting outdoor kitchen area equipped with a grill and dining set overlooks a lush garden. A cozy indoor living space features a plush sofa and a large TV. The private pool, framed by lounge chairs and greenery, offers a tranquil oasis for relaxation.
Condo in El Chirú
5 out of 5 average rating, 23 reviews

Laguna Fun and Sun: Your Escape Awaits

AlyseRating, 5 stars3 weeks ago
La estadía fue increíble, lo disfrutamos de principio a fin, seguramente nuestro anfitrión tiene experiencia en hostelería porque todo fue cinco estrellas.
Superhost
A clear view of a tranquil swimming pool is framed by wooden beams, showcasing reflections of surrounding greenery. Lush tropical plants create a serene backdrop, enhancing the connection to nature.
Home in Gamboa
4.87 out of 5 average rating, 95 reviews

BirdHouse@ Gamboa Panamá Canal

FrancescaRating, 5 stars3 months ago
What an incredible stay we just had. This is our third time to Panama and our first in Gamboa and it was amazing. The home was gorgeous and spacious. The kid zone was a blast for both kids and adults. We went on a zip lining tour and the boat tour of the canal, monkey island and Embera tribe and they were worth every penny. Our 9-12 year olds felt safe and saw every animal on our wish list. Just an amazing adventure topped off by the privacy of our own home with a gorgeous pool. We just loved it. Thank you so much!!!
Top guest favorite
A calm swimming pool reflects the surrounding buildings, with lush palm trees providing greenery. A spacious gazebo is positioned at the pool's edge, accompanied by several shaded lounge chairs for relaxation.
Apartment in Buenaventura
4.99 out of 5 average rating, 102 reviews

Exclusivo apartamento a pasos del mar en Puntarena

IsaacRating, 5 stars4 weeks ago
El apartamento , es tal cual se muestra en las fotos, Dimitrios, muy buen anfitrión , en todo momento , contesta cualquier duda y está pendiente . Amplio el apartamento , muy cómodo . Recomendado .
Guest favorite
A wooden deck surrounds a tranquil pool, complemented by a large umbrella providing shade. Two lounge chairs are positioned nearby, while a round dining table with multiple chairs is visible, set in an inviting outdoor space surrounded by lush greenery.
Home in Playa Bluff
4.89 out of 5 average rating, 44 reviews

Jungle House 100m from the beach

RiaRating, 5 stars1 month ago
The Jungle House at Playa Bluff was a great getaway destination for our 2 families, with 4 adults and 6 children, ages 4-11. The pool was great and the sleeping arrangements worked well for us. There is a decent kitchen, but we mostly ate at nearby restaurants or on our daily adventures. The house is about a 25 min taxi ride from the main town and the road can get soupy, but any of the truck taxis can easily get to the house. The beach is stunning, although not great for swimming with rip tides and currents. The host was super responsive to all questions and I would highly recommend this house. We even saw sloths and monkeys right around the house.
Guest favorite
A scenic view of a beachfront complex features landscaped gardens, multiple swimming pools, and palm trees. The ocean extends to the horizon under a colorful sky. Paths lead towards shaded areas, and guests are visible walking along the manicured pathways.
Condo in San Carlos
4.95 out of 5 average rating, 38 reviews

Lovely Beachfront Condo at Ensenada Beach

OmarRating, 5 stars2 months ago
We had a great time during our short stay, quiet beautiful condo with big windows and a great view of the ocean, it was close to markets and fast food restaurants, great location overall, we are sure to return.
Guest favorite
A modern outdoor pool reflects the surrounding structures, with large glass windows visible in the background. Palm trees line the edges of the pool area, providing a touch of greenery. Lounge chairs are positioned nearby, enhancing the inviting space for relaxation.
Home in Playa Malibú
4.91 out of 5 average rating, 11 reviews

MoMa Malibu, Beach front

EstebanRating, 5 stars1 month ago
Nuestra estancia en esta casa de playa fue absolutamente maravillosa. Desde el primer momento, nos sentimos como en casa gracias a la calidez y la atención a los detalles que se perciben en cada rincón. La ubicación es inmejorable, con el sonido relajante de las olas como banda sonora constante y la playa a solo unos pasos. Disfrutamos muchísimo de los atardeceres desde la piscina. La casa estaba impecable, muy bien equipada y decorada con gusto. Sin duda, unas vacaciones inolvidables. ¡Muchas gracias por compartir este paraíso con nosotros!"

Mansion rentals with a pool

Guest favorite
Vacation home in San Carlos
4.92 out of 5 average rating, 48 reviews

Bienvenidos a nuestra casa de Playa Corona

FranklinRating, 5 stars1 month ago
Es el lugar perfecto para desconectarte de todo y a la vez de todo a minutos. La casa es tal cual la descripción y tiene una vista increíble. Hay árboles frutales, palmas y veraneras hermosas que hacen del lugar un sitio paradisíaco. Fui con mi esposa y 5 hijos adultos, todos estuvieron cómodos. La terraza es enorme y la piscina grande. Full recomendado
Guest favorite
Villa in Rio Hato
4.97 out of 5 average rating, 30 reviews

Villa Agueda Decameron, club de golf y piscina

ManuelRating, 5 stars1 month ago
Todo excelente. La anfitriona fue muy atenta y estuvo siempre pendiente, con una comunicación excelente. El hospedaje es muy lindo, espacioso y cuenta con todas las amenidades que se mencionan en la publicación. Sin duda, recomendado.
Superhost
A scenic view of a spacious outdoor area featuring a refreshing pool surrounded by palm trees. The house is visible with large windows, and seating areas are arranged on the lawn, inviting relaxation in a tropical environment.
Place to stay in Portobelo
4.86 out of 5 average rating, 22 reviews

Villa Frente al Mar

AdrianaRating, 5 stars4 months ago
This place is perfect to enjoy a relaxing het away, having the beautiful ocean view and tropical breeze right outside of the house it is priceless! The pool and Jacuzzi are well maiy and make a great complement of the whole experience! The host thought about every detail to make the guests very welcome, by providing essentials for personal cleaning products, kitchen extra essentials and outdoors supplies. We really enjoyed the stay.!
Top guest favorite
A bright living area features large glass doors that provide a panoramic view of the beach and ocean. A spacious sectional sofa is positioned near natural light, complemented by a wooden dining table. Elegant decor elements include woven light fixtures and fresh greenery.
Condo in Maria Chiquita
4.98 out of 5 average rating, 55 reviews

Playa Escondida Lux Beachfront Haven:Oceanview Apt

GiselleRating, 5 stars1 month ago
Excelente. Nos encantó. Fuimos en familia y nos sentimos como en casa. El apto. tenía excelente vista a la playa, muy amplio, acogedor y cómodo. Samy es un excelente anfitrión, siempre pendiente de todo. Full recomendado.
Guest favorite
A tranquil pool area is framed by lush palm trees, with a clear view of the beach in the background. The inviting water of the pool reflects the bright blue sky, creating a serene atmosphere for relaxation. A white lounge chair is positioned nearby.
Chalet in Las Lajas
4.79 out of 5 average rating, 66 reviews

Front beach exclusive Villa.

ArianaRating, 5 stars2 months ago
Just returned from an incredible stay at Rafael’s beautiful beachfront home in Las Lajas, where we gathered to celebrate my mom’s 70th birthday. The house was perfect for our family—spacious, welcoming, and thoughtfully designed. Four of the five bedrooms had their own private bathrooms, making it easy for everyone to have their own space. The master bath was a dream with its Jacuzzi tub and separate shower, another had a soaking tub and rain shower, and the others featured spa-like rain showers. We enjoyed slow mornings with ocean views, meals in the fully equipped kitchen, and evenings by the pool. Rafael was a wonderful host—responsive and kind. This home helped us create memories we’ll never forget.
Guest favorite
A serene outdoor area is showcased, featuring a swimming pool surrounded by well-maintained grass and a decorative fountain in the foreground. Lounge chairs are positioned near the pool, while lush greenery offers a sense of privacy.
Home in Panama City
4.95 out of 5 average rating, 40 reviews

Agradable Casa Duplex con piscina.

MaricelRating, 5 stars1 day ago
Don Gerardo was an amazing host. He picked my family and I up from the airport and welcomed us to his place with a cake which he did not need to do at all. He went above and beyond by offering us advice on local spots and attractions and completely changing the washing machine when the last one had issues. He was very attentive and welcoming to my elderly parents. He even drove my daughter back home from the airport after dropping her off there (one hour round trip) as she had forgotten something important at his place. The house was huge and exactly what my family and I needed. There were no issues at all from the house apart from the aforementioned washing machine which he rectified immediately when we were out of the house. Would definitely recommend to anyone with a big family to stay in Gerardo’s place. He is just an amazing guy and super super host . Highly recommended
Superhost
A large outdoor space features a kidney-shaped swimming pool with a connected hot tub, surrounded by lush greenery and palm trees. The pool area is bordered by vibrant stone pathways and a small building with a clay tile roof in the background.
Home in PA
4.8 out of 5 average rating, 95 reviews

Villa GiGi - Beach Home Panama Santa Clara

JohannaRating, 5 stars3 months ago
La pasamos super bien en familia, nos sentiamos como en casa, ambiente tranquilo, todo era como en las fotos, nos divertimos mucho, muy cerca de la playa, Sr. Benito muy atento. Esperamos poder regresar pronto
Guest favorite
A well-lit bedroom features a spacious bed with white linens and colorful accent pillows. Two nightstands with green lamps are positioned beside the bed. Natural light enters through a window with sheer curtains, and a ceiling fan is mounted above, enhancing ventilation.
Condo in El Chirú
4.96 out of 5 average rating, 28 reviews

Buenaventura | Luxury Beach Apartment | Panama

RenataRating, 5 stars1 month ago
Nuestra estadía en el apto de Rapha fue espectacular. El apartamento es super cómodo para estar con familia, esta muy bien equipado y muy limpio. Tienen además detalles que te hacen sentir en casa, como silla para bebes, platos, vasos, etc. Nos encantó el sitio, el apartamento y la atención que recibimos por parte de Rapha! Sin duda volveremos y lo recomendamos al 100%.

Destinations to explore

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