House vacation rentals in Downtown Durham

4.89 out of 5 average rating, 130 reviews

A charming single-story home is set on a lush green lawn, featuring a classic front porch with white railings and blue shutters. A brick chimney adds character, while the pathway leads to the entrance, surrounded by neatly trimmed hedges.

Home in Colonial Village

Entire Cottage with Yard and Fire Pit

Sitting on a sunny, corner lot, our home is the perfect spot to be your home away from home! Enjoy the sunrise w/your favorite beverage on the sweet front porch, and out back, you'll love the firepit + deck with a gas grill. Inside, you'll find natural light throughout, a well-stocked kitchen w/updated, modern appliances, reliable wifi + a smart tv ready for your own streaming logins. Close to everything too! We can't wait to host you! Early check in + late check out avail. for an additional fee

A modern duplex with a welcoming front porch is showcased. The porch features wooden railings and potted plants on either side. A clear pathway leads to the entrance. The structure is set against a backdrop of trees and an expansive yard.

4.93 out of 5 average rating, 125 reviews

Luxe Modern Retreat *Entire Duplex/ Both Units!*

This stylish modern retreat is sure to become your new favorite getaway. You’ll enjoy access to the ENTIRE DUPLEX (both units!), perfect for traveling with friends, family, or colleagues. Each of the 2 units boasts its own beautiful living room and kitchen, plus 2 bedrooms & 1 bathroom per side. Gather together on the inviting front porch, or enjoy dinner alfresco on the sunny back patio. Ideally situated just 1 mile from the heart of Durham, you’ll enjoy all the best the Bull City has to offer!

The exterior of the bungalow is presented, showcasing a well-maintained side with fresh white siding and a new roof. A welcoming red front door is highlighted, flanked by small shrubs and decorative landscaping. Tall trees are visible in the background, adding natural greenery.

4.95 out of 5 average rating, 163 reviews

Mirabelle- 3bd Downtown/Duke/RTP/No Cleaning Fees

Step into the comfort of this stylish, newly renovated 3- bedroom, 1- bath bungalow! CENTRALLY LOCATED & NEAR ALL MAJOR HIGHWAYS, Mirabelle is just minutes from downtown Durham, Duke University & RTP. No matter what brings you to Durham, Mirabelle has the perfect location & convenient amenities you’re looking for! * 5 min from downtown Durham * 10 min from Duke University & Duke Hospital * 10 min from RTP * 15 min from RDU airport * 10 min from Durham bulls and DPAC * 15 min from UNC hospital

A spacious living area features a sleek gas fireplace on one side, with modern artwork displayed on the walls. Comfortable seating includes a large gray sofa and green accent chairs, accompanied by a round coffee table. Natural light floods in through large windows.

4.95 out of 5 average rating, 101 reviews

Modernist Masterpiece: 'Simply the Best'

Welcome to Hazel Modernist 6 - designed and built by Alicia Hylton-Daniel, with her "sister," Modernist 5, next door. Centrally located downtown, this gorgeous escape is truly livable. Fully equipped chefs kitchen opens into the large living & dining space, with Frame TV and fireplace. 3BR & private back deck offer plenty of space together or alone. Each home by Alicia is infused with creative and new design concepts. This glamorous home celebrates the essence of Tina Turner, Simply the Best.

4.98 out of 5 average rating, 253 reviews

A spacious living area is highlighted by a vibrant orange couch adorned with decorative pillows. Large windows fill the space with natural light, complemented by green plants that bring a touch of nature indoors. The open layout leads to a modern kitchen in the background.

Home in Hope Valley

Artist-Designed Cabin Near Duke & Downtown

Relax and recharge in a modern, artist-designed passive solar home tucked into the woods just minutes from downtown Durham and Duke University. This cabin-style retreat blends nature, comfort, and convenience — ideal for weekend getaways, visiting Duke, or extended stays. Inside you’ll find original artwork, abundant natural light, and a professionally equipped kitchen. Outside, enjoy birdsong and mature trees while staying close to Durham’s restaurants, coffee shops, breweries, and shopping.

4.9 out of 5 average rating, 468 reviews

A well-groomed dog stands on a wooden deck with a backdrop of lush greenery. Sunlight filters through the trees, creating a serene outdoor space. The deck features a blend of natural wood surfaces, complementing the relaxed atmosphere and inviting nature views.

Home in Forest Hills

The Bird's Nest

This newly renovated lower level apartment is nestled in the peaceful Forest Hills neighborhood. Our space is in an ideal location to enjoy all that Durham has to offer and comes complete with everything you'll need to feel at home. Minutes from excellent restaurants, outdoor fun, and cultural entertainment. Enjoy an evening at DPAC, a Durham Bulls baseball game, an energizing game of tennis at Forest Hills park, or a relaxing stroll through Duke Gardens. All just minutes from our doorstep.

4.97 out of 5 average rating, 168 reviews

A spacious rooftop deck presents a conversation area with a grey sectional sofa and a circular coffee table. A dining set for six with a light-colored table is positioned nearby, complemented by an 11-foot retractable umbrella. Surrounding greenery enhances the serene atmosphere.

Home in Forest Hills

*Rooftop Patio Oasis*House Near DT, Duke, RTP

Enjoy this wonderful Rooftop Oasis less than a mile to downtown, 2 miles from Duke University -conveniently close to all Durham has to offer. The Historic Tobacco Trail is literally in the back yard! Take a short walk to a Durham Bulls game or one of the many great picks for good eats in the city. You are truly on "Cloud Durham" when relaxing in good company on the rooftop deck. Take a meal to the outdoor dining table or converse on the sofa under the sky in the daylight or the deck light!

The kitchen area features white cabinetry and a wooden countertop. A modern fridge is positioned next to the entrance door, leading to a cozy living area with a brown sofa and a bright red chair. A colorful wall art piece adds a touch of decoration.

4.91 out of 5 average rating, 221 reviews

Clean Quiet Medical&Work Stay, Fenced Yard, Pets

Welcome to a spotlessly clean, quiet, and comfortable home in downtown Durham, thoughtfully set up for medical stays, longer work visits, and guests traveling with pets. Many guests choose this home while visiting Duke University Hospital, the VA Hospital, or Duke University, and appreciate having a calm place that feels easy to live in during what can be stressful or busy times. This is not a party house —it’s a peaceful, practical space designed to help you rest, reset, and settle in.

4.94 out of 5 average rating, 157 reviews

This historic home features a charming exterior with light green siding and a welcoming front porch. Surrounded by lush greenery and flower beds, the inviting walkway leads to the entrance, showcasing typical architectural details of the era.

Home in Downtown Durham

Rustic Historic Home~Short Walk to Downtown Durham

This historic home is only minutes from downtown Durham. It sits in one of the most beautiful neighborhoods in old Durham. It’s tree lined sidewalks can take you to parks, running paths and to one of the most vibrant downtowns in North Carolina . We are happy to offer you this 4 bedroom with 2 full bathrooms home with a well stocked kitchen with most everything you made need for making those epic dinners. Our large porch is a perfect place to hang out true to the southern style of leisure.

A single-story bungalow is displayed with a light blue front door. Symmetrical windows flank the door, and manicured shrubs are positioned on either side of the entrance. A concrete path leads up to the porch, enhancing the welcoming appearance.

4.99 out of 5 average rating, 192 reviews

Downtown Luxury/King Beds/ Walk Everywhere

Enjoy this luxury bungalow perfectly located in Downtown Durham. Walk to the best that Durham offers! Immaculately furnished throughout. King beds with two en suite full bathrooms. Wake up and walk to CocoCinnamon to enjoy a delicious morning cup of coffee. Later in the day, Motorco, Full Steam Brewery, The Farmers Market, Central Park, Saltbox Seafood Shack, and downtown restaurants galore await you to enjoy. DPAC and the Durham Bulls will be unforgettable nights out. Perfect location!

A cozy living area features a gray sofa paired with a wooden coffee table and a woven area rug. A comfortable chair is situated nearby, while a sleek floor lamp illuminates the space. A decorative fireplace with a chalkboard backdrop adds character to the room.

4.95 out of 5 average rating, 344 reviews

Reclaimed Beauty in Downtown's Cleveland-Holloway

Stay in a renovated, simplified Queen Anne-style home from 1915, located on the edge of Durham's Cleveland Holloway neighborhood with easy access to downtown's farmers market, restaurants, and bars. A portion of your stay goes to Airbnb.org to support hosting refugees. Relax in a spacious kitchen with Little Waves coffee, high ceilings, a beautiful live edge slab table, and a luxurious clawfoot tub shower. Please note, there is only one bathroom located in the master bedroom.

4.82 out of 5 average rating, 188 reviews

The exterior of a historic Craftsman duplex is highlighted, featuring a welcoming front porch with exposed brick steps. A landscaped yard with low shrubs and fallen leaves is visible, framed by trees and nearby homes, creating a serene neighborhood setting.

Home in Downtown Durham

Historic Duplex with Patio

Discover the charm of this historic Craftsman duplex in Durham's Cleveland Holloway neighborhood. Enjoy a fully equipped kitchen. Relax in a cozy space with modern amenities, including a Smart TV, laundry facilities, and a subway-tiled bathroom. Enjoy a cup of coffee in the morning in your private courtyard. Conveniently located near downtown, this house offers a perfect blend of history and comfort.

Popular amenities for Downtown Durham house rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

A welcoming living area features a comfortable sectional sofa and two armchairs, arranged on a light area rug. A wooden coffee table occupies the center, adorned with decorative elements. Natural light filters through nearby windows, enhancing the open and airy layout.

4.98 out of 5 average rating, 65 reviews

1 story Ranch in South Durham/RTP/UNC/Duke/ RDU

4.7 out of 5 average rating, 40 reviews

Home in Hope Valley

Peaceful, townhome in Hope Valley Farms

4.74 out of 5 average rating, 23 reviews

A charming bungalow exterior features a welcoming front porch adorned with turquoise chairs. The landscaped yard includes a grassy area framed by wooden steps, inviting relaxation. The structure showcases a light-colored facade paired with a gray roof, surrounded by greenery under a clear blue sky.

Home in East Durham

Adorable Bungalow, Minutes from Downtown Durham

4.88 out of 5 average rating, 8 reviews

The exterior of the home features a vibrant blue facade complemented by wooden accents. A spacious front porch is supported by two columns, providing sheltered entry. The yard includes a manicured lawn with small plants and a paved walkway leading to the entrance.

Home in Lyon Park

Stylish Downtown Durham Home

4.79 out of 5 average rating, 124 reviews

The front of the home features a charming exterior with blue shutters and a welcoming entrance. Lush purple flowers bloom vibrantly in the landscaped yard, complemented by green shrubs and a small tree. A driveway is visible, leading to the side of the house.

Home in Woodlake

3bd Lake pool access near Duke UNC Southpoint

4.83 out of 5 average rating, 12 reviews

A cozy living room is characterized by two framed windows dressed with patterned curtains, allowing natural light to illuminate the space. A comfortable sofa, accented with striped cushions, faces a white coffee table. A rustic brick fireplace adds a touch of historic charm to the room.

Home in Hillsborough

Cottage & Pool, Steps to Historic Downtown

4.93 out of 5 average rating, 41 reviews

A spacious living area features gray sectional sofas and a cozy armchair, arranged around a central rug. Natural light pours in through large windows, showcasing views of the outdoors. A flat-screen TV is mounted above a white brick fireplace, enhancing the comfort of the space.

Home in Chapel Hill

The Cozy Cottage - 10 Min From UNC

A modern two-story home is presented with a light exterior, featuring a front porch and a driveway leading to a garage. The surrounding landscape includes a grassy area and trees in the background under a blue sky with fluffy clouds.

4.69 out of 5 average rating, 35 reviews

New Modern Home in the heart of Downtown Durham

Weekly house rentals

4.83 out of 5 average rating, 36 reviews

Perfect Home in Downtown Durham, close to Duke!

The living room features a spacious sofa and loveseat arranged around a central coffee table. A large smart TV is mounted on the wall opposite. Bright windows allow natural light, enhancing the airy feel, while decorative plants and artwork add subtle charm.

5 out of 5 average rating, 37 reviews

5 BR Luxurious New Downtown Home | 2 miles Duke

4.83 out of 5 average rating, 23 reviews

Home in West End

Cozy Durham Getaway near Downtown

4.8 out of 5 average rating, 20 reviews

An open plan living space features a cozy sectional sofa with contrasting cushions, a round coffee table, and a dining area with a wooden table and six chairs. The kitchen is equipped with stainless-steel appliances and ample counter space. Natural light enters through the nearby window.

Home in Duke Park

Durham Cottage | 1 Mi to DT Durham

4.92 out of 5 average rating, 97 reviews

A cozy living area is highlighted by an inviting red sofa and a flat-screen TV mounted on the wall. Natural light filters in through a nearby window, while a kitchenette with a microwave and mini-fridge is positioned on a shelving unit. Exposed wooden beams add character to the high ceiling.

Home in Hope Valley

Guest Suite: Artist studio turned into loft.

5 out of 5 average rating, 6 reviews

BW Express Back Unit near Duke/UNC/Downtown/NCCU

4.95 out of 5 average rating, 58 reviews

A spacious living room features a cozy seating arrangement with a gray sofa and two armchairs. Natural light enters through large windows, highlighting a decorative fireplace. A television is mounted above the mantle, and a textured rug adds warmth to the wooden floor.

Home in Burch Avenue

Burch Avenue Hideaway- walk to Duke

4.75 out of 5 average rating, 4 reviews

A single-story house features a welcoming front porch adorned with two black chairs. The entrance is highlighted by a green door, flanked by windows with dark shutters. Lush greenery surrounds the brick steps, and a stone pathway leads through the neat lawn.

Home in East Durham

Cozy Home in Old East Durham

Private house rentals

4.9 out of 5 average rating, 77 reviews

Home in East Durham

3BR Bungalow 5 min to Downtown Durham Free Parking

4.83 out of 5 average rating, 59 reviews

A bright living room features a comfortable sofa and a modern coffee table at its center. Large windows allow natural light to filter in, complemented by neutral-toned walls and light wood flooring. A simple fireplace adds a touch of character, while a ceiling fan circulates air.

Home in Lyon Park

Cozy Home minutes from Duke Hospital & Downtown

4.91 out of 5 average rating, 11 reviews

Home in Duke Park

Cozy Bungalow 5 Mins to Downtown

4.97 out of 5 average rating, 32 reviews

The charming exterior of a bungalow is framed by well-maintained landscaping, including a small tree and lush greenery. A welcoming front porch features a rocking chair, while a brick pathway leads to the dark front door, inviting guests to enter.

Home in Trinity Park

Charming Trinity Park Garden Home Walkable to Duke

An open kitchen features granite countertops with a sink and modern appliances. Beside it, a round dining table with white chairs is set. Large windows allow natural light to fill the space, highlighting the airy living area in the background with seating arrangements.

4.84 out of 5 average rating, 49 reviews

Durham Bull City DTown Bungalow (Pups Welcome!)

A welcoming living area features two white accent chairs facing a grey sofa, creating a cozy seating arrangement. Natural light enters through multiple windows, and a decorative rug lays on the hardwood floor. A mounted TV and a fireplace add to the room's functionality.

5 out of 5 average rating, 39 reviews

NEW! Bull City Oasis - Prime Location

4.93 out of 5 average rating, 56 reviews

A welcoming living area features a red sofa complemented by colorful throw pillows. Two blue chairs are positioned near a circular coffee table. The space is illuminated by soft ceiling lights, with a modern rug anchoring the wooden floor. A kitchen peninsula with barstools is visible in the background.

Home in Trinity Park

“Crash” - 1.5 br/1 ba three blocks from Duke

The living area features a combination of modern furniture, including a green sofa, orange chairs, and a round patterned ottoman. A central coffee table sits atop a black and cream geometric rug, while natural light streams in through multiple windows, illuminating the warm color palette.