House vacation rentals in Durham County

A charming single-story home is set on a lush green lawn, featuring a classic front porch with white railings and blue shutters. A brick chimney adds character, while the pathway leads to the entrance, surrounded by neatly trimmed hedges.

4.89 out of 5 average rating, 130 reviews

Entire Cottage with Yard and Fire Pit

Sitting on a sunny, corner lot, our home is the perfect spot to be your home away from home! Enjoy the sunrise w/your favorite beverage on the sweet front porch, and out back, you'll love the firepit + deck with a gas grill. Inside, you'll find natural light throughout, a well-stocked kitchen w/updated, modern appliances, reliable wifi + a smart tv ready for your own streaming logins. Close to everything too! We can't wait to host you! Early check in + late check out avail. for an additional fee

A modern duplex with a welcoming front porch is showcased. The porch features wooden railings and potted plants on either side. A clear pathway leads to the entrance. The structure is set against a backdrop of trees and an expansive yard.

4.93 out of 5 average rating, 125 reviews

Luxe Modern Retreat *Entire Duplex/ Both Units!*

This stylish modern retreat is sure to become your new favorite getaway. You’ll enjoy access to the ENTIRE DUPLEX (both units!), perfect for traveling with friends, family, or colleagues. Each of the 2 units boasts its own beautiful living room and kitchen, plus 2 bedrooms & 1 bathroom per side. Gather together on the inviting front porch, or enjoy dinner alfresco on the sunny back patio. Ideally situated just 1 mile from the heart of Durham, you’ll enjoy all the best the Bull City has to offer!

The exterior of the bungalow is presented, showcasing a well-maintained side with fresh white siding and a new roof. A welcoming red front door is highlighted, flanked by small shrubs and decorative landscaping. Tall trees are visible in the background, adding natural greenery.

4.95 out of 5 average rating, 161 reviews

Mirabelle- 3bd Downtown/Duke/RTP/No Cleaning Fees

Step into the comfort of this stylish, newly renovated 3- bedroom, 1- bath bungalow! CENTRALLY LOCATED & NEAR ALL MAJOR HIGHWAYS, Mirabelle is just minutes from downtown Durham, Duke University & RTP. No matter what brings you to Durham, Mirabelle has the perfect location & convenient amenities you’re looking for! * 5 min from downtown Durham * 10 min from Duke University & Duke Hospital * 10 min from RTP * 15 min from RDU airport * 10 min from Durham bulls and DPAC * 15 min from UNC hospital

A two-story house is presented in a neutral color with white trim and black shutters. The front porch features a welcoming entrance and steps leading to the door. Surrounding trees provide a natural backdrop, and a driveway offers access to the property.

4.87 out of 5 average rating, 154 reviews

Charming home betw. Duke & UNC with wooded trails

Relax with the whole family at this peaceful home between Duke and UNC, in one of the triangle's best neighborhoods. Woods everywhere, yet close to dining and shopping, coffee shops and farm stands. Just a six mile drive to Duke, UNC, and RTP, so literally in the center of everything, yet so peaceful! Enjoy modern kitchen, fireplace, fiber Internet & great outdoor spaces! We are glad to host you and we live right down the street, so come and relax and let us know if you need anything at all.

A spacious living area features a sleek gas fireplace on one side, with modern artwork displayed on the walls. Comfortable seating includes a large gray sofa and green accent chairs, accompanied by a round coffee table. Natural light floods in through large windows.

4.95 out of 5 average rating, 101 reviews

Modernist Masterpiece: 'Simply the Best'

Welcome to Hazel Modernist 6 - designed and built by Alicia Hylton-Daniel, with her "sister," Modernist 5, next door. Centrally located downtown, this gorgeous escape is truly livable. Fully equipped chefs kitchen opens into the large living & dining space, with Frame TV and fireplace. 3BR & private back deck offer plenty of space together or alone. Each home by Alicia is infused with creative and new design concepts. This glamorous home celebrates the essence of Tina Turner, Simply the Best.

Superhost

4.96 out of 5 average rating, 143 reviews

Luxury Modern Suite W/ Private Deck

Welcome to our Private Luxury Master Suite! Enjoy a hotel-like experience with a spacious luxury bath featuring double sinks and a rain shower and a beautiful private deck with a peaceful view. We also include a coffee bar, work area, Wi-Fi, and TV. Conveniently located from RDU Airport and Downtown Durham, with a variety of restaurants and coffee shops nearby. Experience the perfect blend of comfort, luxury, and convenience in this upgraded suite! Parking is available and limited to 1.

A spacious living area is highlighted by a vibrant orange couch adorned with decorative pillows. Large windows fill the space with natural light, complemented by green plants that bring a touch of nature indoors. The open layout leads to a modern kitchen in the background.

4.98 out of 5 average rating, 253 reviews

Artist-Designed Cabin Near Duke & Downtown

Relax and recharge in a modern, artist-designed passive solar home tucked into the woods just minutes from downtown Durham and Duke University. This cabin-style retreat blends nature, comfort, and convenience — ideal for weekend getaways, visiting Duke, or extended stays. Inside you’ll find original artwork, abundant natural light, and a professionally equipped kitchen. Outside, enjoy birdsong and mature trees while staying close to Durham’s restaurants, coffee shops, breweries, and shopping.

A well-groomed dog stands on a wooden deck with a backdrop of lush greenery. Sunlight filters through the trees, creating a serene outdoor space. The deck features a blend of natural wood surfaces, complementing the relaxed atmosphere and inviting nature views.

4.9 out of 5 average rating, 468 reviews

The Bird's Nest

This newly renovated lower level apartment is nestled in the peaceful Forest Hills neighborhood. Our space is in an ideal location to enjoy all that Durham has to offer and comes complete with everything you'll need to feel at home. Minutes from excellent restaurants, outdoor fun, and cultural entertainment. Enjoy an evening at DPAC, a Durham Bulls baseball game, an energizing game of tennis at Forest Hills park, or a relaxing stroll through Duke Gardens. All just minutes from our doorstep.

Superhost

A cozy living room is featured, showcasing a grey sofa alongside two yellow accent chairs. A dark coffee table rests in the center, complemented by light walls and a patterned rug. Natural light filters in through multiple windows, enhancing the space's bright ambiance.

4.88 out of 5 average rating, 138 reviews

Desirable Family Neighborhood, Near Duke/Hospital

This beautifully renovated home offers a warm and inviting atmosphere, just minutes from a golf course, Downtown Durham, parks, shopping, and I-85. Enjoy scenic walking trails just down the block, museums, and restaurants. The home is also conveniently located near major hospitals, including Duke and VA Hospitals, as well as rehabilitation centers. Perfect for 2-4 adults or a small family, with a fully fenced backyard. Pet-Friendly: Pre-approved dogs (up to 2) allowed with a $125 charge.

A screened porch is illuminated by soft string lights, casting a warm glow against the exterior of the house. The porch features wooden furniture, and a well-maintained lawn is visible in the foreground. A tall tree provides shade beside the porch.

4.97 out of 5 average rating, 110 reviews

Near Duke, Southpoint, UNC

Discover the perfect retreat in South Durham, NC! Our tranquil Airbnb offers an idyllic escape with a prime central location that guarantees a memorable stay. Start your morning on the inviting screen porch, where you can relish a cup of coffee and take in the view of the flower garden before headed out to enjoy some of the Triangle's finest attractions. Convenience is at your fingertips, as our Airbnb is just minutes away from RTP, RDU airport, Downtown Durham, DUKE, UNC, and the DPAC.

The exterior of a renovated single-story home is presented, featuring a neutral color palette and a well-maintained yard. A front porch with black railings is visible, alongside inviting landscaping. A gravel driveway leads to the entrance, surrounded by trees providing a natural backdrop.

4.93 out of 5 average rating, 122 reviews

Newly Renovated 3 BR home in convenient location!

Newly renovated space to relax and explore the best of Durham. Sleeps 6 with plenty of space to spread out. Well located - only 10 minutes to Duke, Duke Hospital, downtown and Ninth/Broad Street areas. Enjoy use of the fully stocked kitchen, comfortable living area, dining space and spacious back deck and screened in porch. Grill out and enjoy the back yard. Great for families and groups of friends or business travelers. Several restaurants close by and easy access to highways.

A cozy living area features a gray sofa paired with a wooden coffee table and a woven area rug. A comfortable chair is situated nearby, while a sleek floor lamp illuminates the space. A decorative fireplace with a chalkboard backdrop adds character to the room.