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Family-friendly vacation rentals in Seneca

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Seneca

Guests agree: these family-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Westminster
4.99 out of 5 average rating, 145 reviews

Lakeside Retreat • Pet friendly • Fire Pit

Wake up to peaceful lake views, sip coffee on the screened porch, and end your day in the hot tub under the stars. Dream Weaver Cottage is a private, pet-friendly lakeside retreat designed for families, friends, and four-legged travelers with a fenced yard, beach access, kayaks, and cozy gathering spaces. It’s the perfect place to relax and reconnect. Guest favorites: • Sandy beach & lake access • Luxury Hot Tub • Fully fenced yard for kids & dogs • Screened porch with lake views • Fire pit

Top guest favorite
A spacious living area features two sofas, one in a deep blue hue, and a black armchair, arranged around a light area rug. A television is mounted above a classic fireplace, and a dining table accommodates several chairs. Large windows provide natural light.
Home in Seneca
4.95 out of 5 average rating, 126 reviews

Hanover Haven 3 BR/2 Bath

Hanover Haven is located close to all you need! Clemson University is only 3 miles away. There are 3 full grocery stores within 5 minutes. Lake Keowee access and marina all within 5 miles. The Gathering space is such a great place to have family fun! There are card games and large TVs with multiple streaming platforms. We are also working on a great outdoor space that will include a grill and sail shade ready for the summer. There is also an RV on the property that is an AirBNB with privacy.

Top guest favorite
A spacious outdoor dining area is visible through a large hinge window. The wooden table is surrounded by four folding chairs, with a scenic view of the lake and trees in the background. Sunlight filters through, enhancing the seamless indoor-outdoor connection.
Cottage in Seneca
4.99 out of 5 average rating, 115 reviews

Destination Keowee

A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Superhost
A geodesic dome is illuminated from within, set against a backdrop of trees. An adjacent wooden structure features outdoor seating under string lights, creating a welcoming atmosphere for relaxation. The natural environment is highlighted, emphasizing the dome's unique design.
Dome in Salem
4.89 out of 5 average rating, 353 reviews

G.O.A.T. Geodome: Farm Animals, Hot Tub, Zip Line

Glamping: where luxury meets the outdoors. This geodesic structure offers a rare opportunity to experience the outdoors without the elements. Complete with kitchen, AC & heat, dual control heated mattress pad, fully functioning bathroom, and sunrise views over the pasture. Whether you are looking to relax and enjoy feeding the farm animals, have an adventure riding the zip line, or indulge in a romantic evening sipping wine in the hot tub under the stars, you will leave with lasting memories.

Top guest favorite
The cottage exterior displays warm wood siding with large windows allowing natural light. A welcoming front porch features two chairs and a small plant, while a grill stands nearby. Surrounding landscaping creates a serene atmosphere in a private setting.
Cottage in Central
5 out of 5 average rating, 203 reviews

The Wildflower

Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

Top guest favorite
A cozy bedroom is highlighted by a spacious bed with a patterned blanket. Two bedside lamps provide soft illumination on either side. A wooden dresser is positioned against the wall, and a window allows natural light to fill the space, complemented by cream-colored walls.
Apartment in Seneca
4.94 out of 5 average rating, 178 reviews

Clemson Mom Apartment

Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

Top guest favorite
A comfortable living room is presented with two sofas, a wooden coffee table, and a rustic stone fireplace. A television rests on a wooden media console, while natural light enters through nearby windows. The flooring is finished in a warm tone, creating an inviting space.
Home in Seneca
4.95 out of 5 average rating, 195 reviews

Private lake setting close to Clemson University

House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

Top guest favorite
The exterior of a cottage features a covered porch with two rocking chairs, surrounded by well-maintained landscaping. The building has a gray exterior, dark blue shutters, and a welcoming entrance, with trees providing a natural backdrop.
Cottage in Williamston
4.96 out of 5 average rating, 137 reviews

Charming cottage on a Family Farm.

Your family will relish the convenience of this centrally located accommodation, along with spectacular views of farm animals. This charming 2-bedroom, 1-bathroom cottage is nestled on a quaint family farm, just a 5-minute drive from Interstate 85, exits 32 and 27. Conveniently positioned between Greenville and Anderson, it's also only a 20-minute drive to Clemson from the cottage. Moreover, the cottage features a fenced yard, and pets are welcome!

Top guest favorite
The exterior of a modern tiny house is depicted, featuring a dark blue façade and large windows allowing natural light to fill the interior. The covered porch is accessible from the gravel pathway, and greenery surrounds the property, enhancing the wooded setting.
Cottage in Westminster
4.97 out of 5 average rating, 629 reviews

Tiny house

BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

Top guest favorite
A charming tiny house is set amidst wooded surroundings, featuring a welcoming entrance with a white door and a light-colored roof. Two white chairs and a small table are positioned on a wooden porch, complemented by a grill nearby. Lush greenery enhances the tranquil setting.
Tiny home in Seneca
4.96 out of 5 average rating, 256 reviews

Windmill Cottage

You’ll treasure your time at this cute little cottage. It is 295 sq feet and was built in 2023 at the edge of the woods on our property. It has a full kitchen, bedroom with a queen bed, bathroom and living room. It is perfect for one or two people, for either a quiet get-away in the country or for someone who is in town for work and is looking for a more extended stay. We offer discounts for weekly/monthly stays!

Top guest favorite
A bright and spacious kitchen features a central island with a granite countertop, surrounded by blue upholstered chairs. A dining table with wicker chairs is located nearby, and natural light fills the room through sliding glass doors leading to the outdoor area.
Home in Seneca
4.96 out of 5 average rating, 129 reviews

5 Min to Clemson | Large Driveway & Self Check-In

Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Top guest favorite
A charming cottage is surrounded by lush greenery and tall trees, featuring a welcoming front porch with seating. The exterior is clad in grey siding and highlights stylish architectural design elements. A gravel driveway leads up to the house, emphasizing its peaceful and private setting.
Home in Seneca
5 out of 5 average rating, 116 reviews

The Cottage

Come relax and refresh in peaceful surroundings. Relax and unwind on the front porch. Experience tranquility as the sun sets and the frogs start croaking. You are welcome to cast a line in the pond to try your skill at fishing. Fishing poles are not provided. The cottage is private but still has convenience of Walmart and Oconee Memorial Hospital within a 5 minute drive. We are 13 miles from Clemson.

Popular amenities for Seneca family-friendly rentals

Quick stats about vacation rentals that are family-friendly in Seneca

  • Total vacation rentals

    Explore 50 vacation rentals in Seneca

  • Nightly prices starting at

    Seneca vacation rentals start at G$16,728 GYD per night before taxes and fees

  • Verified guest reviews

    Over 1,520 verified reviews to help you choose

  • Pet-friendly vacation rentals

    Find 10 rentals that welcome pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wi-Fi availability

    50 of Seneca vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Seneca rentals

  • 4.9 Average rating

    Seneca stays are highly rated by guests—averaging 4.9 out of 5!