
Lake house vacation rentals in Seneca
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Top-rated lake house rentals in Seneca
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Zoey’s Cottage on Lake Hartwell w/dock- Secluded
This cozy charming and quiet lake property is the perfect getaway for families & friends . Located 5 minutes off I-85 and is 10 minutes to Green pond Landing, 20 minutes to Clemson, Anderson and Seneca. Perfect place to enjoy fishing, shopping and Clemson football games, Enjoy using the back porch to view the sunrise over lake Hartwell and the wildlife as it pass through. The porch is a nice relaxing cozy place where you can enjoy your coffee or a glass of wine while watching the lake glisten.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Lake-House Escape w/Dock, Kayaks, Paddleboards
Gather family or friends for an unforgettable lakeside getaway in a spacious, amenity-loaded lake house in an ultra-private setting. Your group will have a great time on the dock using provided kayaks and paddleboards, fishing, swimming, and more. Bring or rent a boat. Relax on the lakefront screened porch and multiple indoor/outdoor gathering spots. Kids and adults will love watching movies and playing foosball in the game room. Make memories around your choice of beachside or stone firepit.

Cozy Lake House 5 miles from Clemson w Dock
Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

Lake Hartwell house w/ dock 2 miles from Clemson.
This is a simple, comfortable, recently renovated home for Clemson fans and lake vacationers. Decor is vintage/antique. It is 3 1/2 miles to stadium entrance. We have a deep water cove with fire ring, decks, dock, and stairs to gangway, parking for 6 cars, woods and lake on 3 sides, a variety of restaurants nearby. Clemson Marina is next cove over. Clemson golf course across the lake. We are PET FRIENDLY with a max of 2 dogs. There is a $75 pet fee. Read the house rules concerning pets.

Clemson Games + Lake Keowee
Come stay at this new construction home in a Lake Keowee neighborhood, only 8 miles from Clemson and to Death Valley. Whether you're seeking convenient access to Clemson for college activities, such as move-in move out for students, game weekends, or to enjoy Lake Keowee this house is the perfect fit! This house offers plenty of amenities during your stay such as blackout curtains in all the bedrooms, a privacy fence in the backyard for barbecuing, and a ping-pong table in the garage! 

Lakefront Mid-Century Dream Home / 3 mi to Clemson
We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

Hartley’s Haven
Enjoy your stay in this cozy 1 bedroom and 1 bathroom home on Lake Hartwell. We are located 20 minutes from Clemson, 15 minutes to Anderson, and 40 minutes to Greenville, so there is plenty in the area to keep you busy. Located on a dead end street, the neighborhood is very quiet. Our home also has fast wifi and 2 smart TV’s to access any streaming service. We also provide cable. With plenty of parking space in the driveway for vehicles and a boat we can provide a peaceful getaway.

Hidden Lake Sanctuary
Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feeding into Lake Keowee, it’s the perfect escape for nature lovers-especially kayakers. The property comes fully equipped with kayaks and paddle boards. Please note: Access to the dock involves a very steep descent, and the return hike can be challenging—best suited for active guests. Unwind in the private hot tub on the deck or gather around the cozy fire pit.

Paradise Point on Lake Keowee!
Paradise Point – Stunning Views & Luxurious Lakeside Living on Lake Keowee Paradise Point isn’t just a name—it’s a promise. Positioned perfectly along the shore, this Lake Keowee retreat delivers panoramic views that wrap around the property, offering breathtaking water scenes from nearly every room. With 180-degree views along the main side of the home and water visible from both the front and back, it’s one of the most spectacular vantage points on the lake.

Sweet Tea Retreats
We're tickled pink that you are considering Sweet Tea Retreats, a Southern themed Lakefront duplex on Lake Keowee. Clemson Stadium is only 7 miles away! Two separate 2 bedroom 2 bath apartment suites total of 4 bedrooms with 4 en-suite bathrooms, accommodations up to 6 guests. This listing is for both apartment suites, they have been fully renovated with new kitchens and bathrooms, granite and marble countertops and stainless steel appliances.
Popular amenities for Seneca lake house rentals
Waterfront lakehouse rentals

900' of lake front property - 20 min from Clemson

Sunset Point-Best view on Broadway - HOT TUB!

Hardystone LakeHouse Hot Tub & Double Decker Dock!

Lake Escape

DockTales - Panoramic Views & Private Dock

Dujardins Keowee Waterfront Home

Lake House Retreat Near Clemson

Peaceful Lake Keowee Waterfront Home ~Near Clemson
Pet-friendly lake house rentals

Modern Lakefront Cabin on Lake Keowee

Lakeside Retreat • Pet friendly • Fire Pit

Lake Home & Treehouse ❤ Seneca Treehouse Project

Lakefront luxury home w/panoramic view & Boat Slip

Lakefront Home w/Deep Water Dock 20 min to Clemson

New! The Tiger's Perch- Close to Clemson.

Johnsons Cove - Lakefront Retreat With EV Charger

Keowee Lakeside with pool for 16
Private lake house rentals

Preachers Paradise on Lake Hartwell

Lakefront Keowee Luxury Cottage at Keowee Marina

Anchor Point, Lake Retreat - Clemson, 2-story dock

Unique Retreats at Hartwell

Insta-Worthy Lakefront Home w/ Dock + Fire Pit

Calm Water Cove at Keowee near Clemson

Point Lot, Boat and PWC Rental

Clemson Lake House - Dock, Hot Tub, Kayaks
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- Clemson University
- Black Rock Mountain State Park
- Table Rock State Park
- Gorges State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Bell Mountain
- Devils Fork State Park
- Bon Secours Wellness Arena
- DuPont State Forest
- Unicoi State Park and Lodge
- Fred W Symmes Chapel
- Ski Sapphire Valley
- Jump Off Rock
- Chattooga Belle Farm
- Looking Glass Falls
- Dillard House Restaurant
- Fluor Field at the West End
- Anna Ruby Falls
- Tugaloo State Park
- Dry Falls
- Falls Park On The Reedy
- Peace Center
- Jones Gap State Park





