
Lake house vacation rentals in Seneca
Find and book unique lake houses on Airbnb
Top-rated lake house rentals in Seneca
Guests agree: these lake houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Seneca lake house rentals
Waterfront lakehouse rentals

Casa Del Lago on Keowee- Hot Tub and Swimming

Sunset Point-Best view on Broadway - HOT TUB!

Lakefront Keowee Luxury Cottages 127

Anchor Point, Lake Retreat - Clemson, 2-story dock

Dujardins Keowee Waterfront Home

Zoey’s Cottage on Lake Hartwell w/dock- Secluded

Lake Keowee’s Cabin By The Cove, Boat & PWC Option

Fall Football & Lake Views 25 min to Death Valley
Pet-friendly lake house rentals

900' of lake front property - 20 min from Clemson

Highlands-Walk to town! Read our reviews!

Keowee’s family house with hot tub, kayaks, & more

Lake house waterfront, 10 min to downtown w Kayaks

Clemson ,Lake Hartwell, Waterfront, pontoon rental

Keowee Lakeside with pool for 16

A+ Keowee Kustom!*NO Dock!

A Travelers Nest ~ Lake House
Private lake house rentals

High Harbor Point on Quiet Cove

Lake Home & Treehouse ❤ Seneca Treehouse Project

Lake Keowee SC Lakehouse Escape

Lake Keowee Access-Dock-Pool-Grill-Clemson 17 Min

Relaxin’ at Mountain Rest

Lake Hartwell S.C. Retreat private dock /Clemson

Golf view, lake access, 3 pools!

Whitewater Lake Front Cottage
Destinations to explore
- Western North Carolina Vacation rentals
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- Atlanta Vacation rentals
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- Hilton Head Island Vacation rentals
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- Pigeon Forge Vacation rentals
- Cape Fear River Vacation rentals
- North Myrtle Beach Vacation rentals
- Black Rock Mountain State Park
- Gorges State Park
- Tugaloo State Park
- Table Rock State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Mountaintop Golf & Lake Club
- Bell Mountain
- Ski Sapphire Valley
- Wade Hampton Golf Club
- Jump Off Rock
- Don Carter State Park
- Victoria Bryant State Park
- Victoria Valley Vineyards
- Funopolis Family Fun Center
- Old Edwards Club
- Anna Ruby Falls
- Discovery Island
- Carl Sandburg Home National Historic Site
- Haas Family Golf
- Louing Creek
- Chattooga Belle Farm
- City Scape Winery
- Wellborn Winery