
Lake house vacation rentals in Seneca
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Top-rated lake house rentals in Seneca
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Lake Hartwell house w/ dock 2 miles from Clemson.
This is a simple, comfortable, recently renovated (2019) home for Clemson fans and lake vacationers. Decor is vintage/antique. It is 3 1/2 miles to stadium entrance. We have a deep water cove with fire ring, decks, dock, and stairs to gangway, parking for 6 cars, woods and lake on 3 sides, a variety of restaurants nearby. Clemson Marina is 1 cove away. Clemson golf course is across the lake. We are PET FRIENDLY with a max of 2 dogs. There is a $75 pet fee. Read the house rules concerning pets.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Cozy Lake House 5 miles from Clemson w Dock
Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

House on Lake Keowee swim beach in cove w/ Dock
This two story home is located at the end of a very quiet cove with plenty of water. The beach has a fresh 6 inches of sand installed for the lake season. The walk to the lake is very short on an almost flat surface. The home will accommodate a family up to six people. The house has two floors. The main floor has a large living room with plenty of comfortable seating and satellite TV service provided. The entire main floor has hard woods along with the Master Bed Room and bed room #2.

Clemson Games + Lake Keowee
Come stay at this new construction home in a Lake Keowee neighborhood, only 8 miles from Clemson and to Death Valley. Whether you're seeking convenient access to Clemson for college activities, such as move-in move out for students, game weekends, or to enjoy Lake Keowee this house is the perfect fit! This house offers plenty of amenities during your stay such as blackout curtains in all the bedrooms, a privacy fence in the backyard for barbecuing, and a ping-pong table in the garage! 

Lakefront Mid-Century Dream Home / 3 mi to Clemson
We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

Hartley’s Haven
Enjoy your stay in this cozy 1 bedroom and 1 bathroom home on Lake Hartwell. We are located 20 minutes from Clemson, 15 minutes to Anderson, and 40 minutes to Greenville, so there is plenty in the area to keep you busy. Located on a dead end street, the neighborhood is very quiet. Our home also has fast wifi and 2 smart TV’s to access any streaming service. We also provide cable. With plenty of parking space in the driveway for vehicles and a boat we can provide a peaceful getaway.

Hidden Lake Sanctuary
Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feeding into Lake Keowee, it’s the perfect escape for nature lovers-especially kayakers. The property comes fully equipped with kayaks and paddle boards. Please note: Access to the dock involves a very steep descent, and the return hike can be challenging—best suited for active guests. Unwind in the private hot tub on the deck or gather around the cozy fire pit.

Lakefront Getaway~Dock~Fire Pit~Kayak & Games!
This 4-bedroom home is in a prime location & has EVERYTHING you need for an amazing vacation in Seneca, SC! • Screened-in Porch w/ Fireplace + Outdoor TV • Dock, Kayak & Paddles! • Fire Pit • Outdoor Patio/Dining • BBQ Grill • Board Games • Fully Stocked Kitchen • Keurig & Drip Coffee Maker • Indoor Fireplace • Family Friendly- Pack n Play & High Chair • Ample Parking • Washer & Dryer • No trailers or boats allowed to be parked on site for more than 5 hours.

Sweet Tea Retreats
We're tickled pink that you are considering Sweet Tea Retreats, a Southern themed Lakefront duplex on Lake Keowee. Clemson Stadium is only 7 miles away! Two separate 2 bedroom 2 bath apartment suites total of 4 bedrooms with 4 en-suite bathrooms, accommodations up to 6 guests. This listing is for both apartment suites, they have been fully renovated with new kitchens and bathrooms, granite and marble countertops and stainless steel appliances.

The Landing Spot
As seen on House Hunters!!!The Landing Spot is your Lake Keowee getaway—just a short walk to the marina with boat rentals, a lakeside restaurant, bar, and more. Close to public beaches, hiking, and downtown Seneca, yet tucked away under dark, starry skies. Game room, digital check-in, and room to relax. Clemson is just 20 minutes away, perfect for visits and game days. A laid-back space for families and friends to enjoy lake life and unwind.
Popular amenities for Seneca lake house rentals
Waterfront lakehouse rentals

Lakeside Retreat • Pet friendly • Fire Pit

Keowee Key Luxury Condo - Stunning Views!

Lakefront+Near Clemson+Dock+Kayaks+Putting Green

Hardystone LakeHouse Hot Tub & Double Decker Dock!

Anchor Point, Lake Retreat - Clemson, 2-story dock

Dujardins Keowee Waterfront Home

Johnsons Cove - Lakefront Retreat With EV Charger

Lake House Retreat Near Clemson
Pet-friendly lake house rentals

Modern Lakefront Cabin on Lake Keowee

900' of lake front property - 20 min from Clemson

Sunset Point - Hot Tub, Private Dock, Swim Beach

Lake Home & Treehouse ❤ Seneca Treehouse Project

Lakefront luxury home w/panoramic view & Boat Slip

Lakefront Home w/Deep Water Dock 20 min to Clemson

New! The Tiger's Perch- Close to Clemson.

Coffee and Kayaks - 5 Bedroom Lakefront Retreat
Private lake house rentals

New Waterfront House with Big Views & Private Dock

Tee House... waterfront on beautiful Lake Keowee

Lakefront Keowee Luxury Cottage at Keowee Marina

Unique Retreats at Hartwell

Clemson Cove - Beautiful new construction on outsk

Cozy, Comfort, Clemson Style

Golf view, lake access, 3 pools!

Point Lot, Boat and PWC Rental
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- Clemson University
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- Table Rock State Park
- Gorges State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Bell Mountain
- Devils Fork State Park
- DuPont State Forest
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