Lake house vacation rentals in Seneca

The Lakeside Nest on Keowee

Nestled in a quiet cove on Lake Keowee, The Lakeside Nest offers the perfect blend of relaxation and convenience. This 4-bedroom, 3-bath sleeps 8 and is ideal for gatherings or game-day weekends with friends. Step out onto the dock for a morning swim, soak up the sun, or unwind on the lake. Located just 10 minutes from Clemson University and close to local groceries and restaurants, you'll have everything you need —whether you're here for Tiger football, a family vacation, or a restful escape fr

Clemson Game Day Lake House with Pontoon Boat

Lake house and pontoon boat with private dock 2.8 miles from downtown Clemson and Death Valley. Perfect game weekend rental! This spacious home has 4 bedrooms and 3 full bathrooms. It has two open living areas with 75” smart TVs and an open kitchen and dining area. The outdoor space has a covered porch, a grill, and a large, flat yard perfect for yard games. There is a deck for outdoor dining and seating. This home is set up for the perfect Clemson weekend getaway! Room for 2 boats at the dock

Modern Lake Vibes – Kayaks, Dock & Fireplace

The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Lake-House Escape w/Dock, Kayaks, Paddleboards

Gather family or friends for an unforgettable lakeside getaway in a spacious, amenity-loaded lake house in an ultra-private setting. Your group will have a great time on the dock using provided kayaks and paddleboards, fishing, swimming, and more. Bring or rent a boat. Relax on the lakefront screened porch and multiple indoor/outdoor gathering spots. Kids and adults will love watching movies and playing foosball in the game room. Make memories around your choice of beachside or stone firepit.

Cozy Lake House 5 miles from Clemson w Dock

Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Private lake setting close to Clemson University

House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

Lake Hartwell house w/ dock 2 miles from Clemson.

This is a simple, comfortable, recently renovated home for Clemson fans and lake vacationers. Decor is vintage/antique. It is 3 1/2 miles to stadium entrance. We have a deep water cove with fire ring, decks, dock, and stairs to gangway, parking for 6 cars, woods and lake on 3 sides, a variety of restaurants nearby. Clemson Marina is next cove over. Clemson golf course across the lake. We are PET FRIENDLY with a max of 2 dogs. There is a $75 pet fee. Read the house rules concerning pets.

Clemson Games + Lake Keowee

Come stay at this new construction home in a Lake Keowee neighborhood, only 8 miles from Clemson and to Death Valley. Whether you're seeking convenient access to Clemson for college activities, such as move-in move out for students, game weekends, or to enjoy Lake Keowee this house is the perfect fit! This house offers plenty of amenities during your stay such as blackout curtains in all the bedrooms, a privacy fence in the backyard for barbecuing, and a ping-pong table in the garage! 

Lakefront Mid-Century Dream Home / 3 mi to Clemson

We excitedly invite you to come enjoy a one of a kind experience at our personal lakefront home. Originally designed and built in the 60s, this home now has all the modern necessities, yet still brims with endless midcentury charm. Located only 3 miles from Clemson, our large outdoor entertainment space and direct access to our private dock invite you to enjoy the many sights and sounds that the lake has to offer. Use our 2 kayaks and canoe, or use the dock to tie up your own boat!

Hartley’s Haven

Enjoy your stay in this cozy 1 bedroom and 1 bathroom home on Lake Hartwell. We are located 20 minutes from Clemson, 15 minutes to Anderson, and 40 minutes to Greenville, so there is plenty in the area to keep you busy. Located on a dead end street, the neighborhood is very quiet. Our home also has fast wifi and 2 smart TV’s to access any streaming service. We also provide cable. With plenty of parking space in the driveway for vehicles and a boat we can provide a peaceful getaway.

Hidden Lake Sanctuary

Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feeding into Lake Keowee, it’s the perfect escape for nature lovers-especially kayakers. The property comes fully equipped with kayaks and paddle boards. Please note: Access to the dock involves a very steep descent, and the return hike can be challenging—best suited for active guests. Unwind in the private hot tub on the deck or gather around the cozy fire pit.

The Landing Spot

As seen on House Hunters!!!The Landing Spot is your Lake Keowee getaway—just a short walk to the marina with boat rentals, a lakeside restaurant, bar, and more. Close to public beaches, hiking, and downtown Seneca, yet tucked away under dark, starry skies. Game room, digital check-in, and room to relax. Clemson is just 20 minutes away, perfect for visits and game days. A laid-back space for families and friends to enjoy lake life and unwind.