
Vacation rentals with lake access in Seneca
Find and book unique lake access rentals on Airbnb
Top-rated lake access rentals in Seneca
Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

Peaceful Living Guest House on quiet cove
1st floor 2 bedrooms, bathroom walk-in shower, and kitchen. Loft family room, TV, Blue-Ray, comfortable furniture; card table, board games, & yoga mats. Access to private dock, gas grill, & outdoor furniture. Parking area 110'x37' up to two trucks w/boat trailers, 7 mi to Green Pond Landing & other access nearby. 20 min to Clemson, Southern Wesleyan University & Anderson University. Firepit, firewood & camp chairs available. EV Tesla’s universal charger. Washer-Dryer for weekly reservation only.

A-Frame Lake Hartwell Cottage w/ Hot Tub
No lake water till it substantially rains Lake Hartwell cottage w/ Hot Tub ! Clemson 9 mi. away! 2 bdrm, 2 full bath, hot-tub, canoe, 2kayaks, 🎣 poles, life-vests, dining & patio table, grill+charcoal, 3tv, Netflix/2DVDplayers/DVDs, kitchen, pots/pans, 2crockpot, microwave, dishwasher+pods, keurig+coffee, washer+detergent, dryer, spices, shampoo/cond, hair dryer, curler, straightener, linens, towels, 3bikes, helmet, Karaoke, firepit+wood, wall of fun! (Boat-landing 1 mi. away! Cateechee Shores

Waterfront cottage w/deep dock 17 miles to Clemson
Welcome to the Queen of Harts, our 2BR/1BA, waterfront cottage on Lake Hartwell w/private, deep water dock. The house is located on a quite street 25 min to Clemson. Interior has been remodeled including farmhouse kitchen sink, butcher block countertops, dishwasher, large bathroom, washer/dryer, and new furnishings. Enjoy beautiful sunsets on the dock or explore the cove on stand-up paddle boards included with rental. Other amenities include wi-fi, 55" Smart TV, charcoal grill, and fire pit.

Hagood Mill Hideaway
Video tour on YouTube "Hagood Mill Hideaway-Air BNB in Upstate South Carolina by Cody Hager Photography". This cabin near Historic Hagood Mill with private fishing pond is perfect for a weekend of relaxing on the porch or while sitting the fire pit. The cabin has a kitchen and gas grill . Smoking, vaping, e‑cigarettes are NOT allowed in the cabin, porch nor the property. We provide a gate pass to Table Rock just 15 min. away. (If the pass is lost during your stay, you will be charged $105 fee)

Destination Keowee
A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Hartwell Hideaway – Dock, Kayaks & Fire Pit
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Beautiful Lake Keowee Condo with great Amenities
"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

Haven on the Lake-Entire downstairs, near Clemson
Beautiful setting on Lake Hartwell. Guests will have the entire downstairs which includes 2 bedrooms, bar area and entertainment area. Guests may bring their boat and dock it. There is plenty of room for trailer parking on premise and the boat ramp is less than 1/4 mile from house. Stay includes 2 hand thrown coffee mugs made by Purple Unicorn Pottery. Please note upstairs is private residence, hosts live there. TEMPORARILY CLOSED FOR COMPlETE REMODEL. SHOULD BE AVAILABLE MAY 2026.

Hidden Lake Sanctuary
Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feeding into Lake Keowee, it’s the perfect escape for nature lovers-especially kayakers. The property comes fully equipped with kayaks and paddle boards. Please note: Access to the dock involves a very steep descent, and the return hike can be challenging—best suited for active guests. Unwind in the private hot tub on the deck or gather around the cozy fire pit.

Holliday's Inn Tiny Tree-house
Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!

Lakefront dock *hot tub* Anderson/Clemson king bed
Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.
Popular amenities for Seneca lake access rentals
Lake access house rentals

Sweet Tea Retreats-Unsweetened B

Waterfall Cove - Prime

Lakefront+Minutes to Clemson+Dock+Kayaks+Fireplace

Pete's Place

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Peaceful Lake Keowee Waterfront Home ~Near Clemson

Lake-House Escape w/Dock, Kayaks, Paddleboards

Lakefront 45 min-Clemson&1 hr-Athens & Greenville
Lake access apartment rentals

Lakeside Getaway

Captain Jack's on the Lake

"Greenbrier" Home in the Joccassee Wilderness

Condo at Lake Keowee

Lake Hartwell - Hartwell Villa 8A

3BR Ground floor condo - 2.4 Miles to Death Valley

3 Bedroom Anderson Condo

The Sugar Shack on Lake Keowee
Lake access cottage rentals

Peaceful Lake Cottage

Lake Front Cottage/Floating Dock

The Blue Pine - A Cozy Updated Lakeside Cottage

Cottage on the Lake

South Cove Cottage ~ Lake Keowee

Sunset Cottage Lake Hartwell

Lakefront cottage with a view, near Clemson

Lake Keowee Waterfront Cottage - Private Retreat
Quick stats about vacation rentals with lake access in Seneca

Total vacation rentals
Explore 20 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at G$25,128 GYD per night before taxes and fees

Verified guest reviews
Over 690 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
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- Rentals with lake access Oconee County
- Rentals with lake access South Carolina
- Rentals with lake access United States
- Black Rock Mountain State Park
- Gorges State Park
- Table Rock State Park
- Bell Mountain
- Tallulah Gorge State Park
- Ski Sapphire Valley
- Helen Tubing & Waterpark
- Jump Off Rock
- Anna Ruby Falls
- Victoria Valley Vineyards
- Carl Sandburg Home National Historic Site
- Soquee River
- Chattooga Belle Farm
- Paris Mountain State Park
- DuPont State Forest
- Unicoi State Park and Lodge
- Clemson University
- Georgia Mountain Coaster
- Memorial Stadium, Clemson
- Oconee State Park
- Devils Fork State Park
- Dillard House Restaurant
- Whitewater Falls
- Babyland General Hospital




