
Vacation rentals with lake access in Seneca
Find and book unique lake access rentals on Airbnb
Top-rated lake access rentals in Seneca
Guests agree: these lake access rentals are highly rated for location, cleanliness, and more.

Lake Keowee Waterfront Cottage - Private Retreat
Lake-front retreat w/ unbelievable sunsets, swimming & kayaking, tucked in between the Cliffs & the Reserve, 30 miles west of Greenville. Private park-like setting for a couples getaway. Updated one-bedroom small cottage w/ living room, kitchen, bath, laundry, AC/heat. The entire property is included w/ your cottage rental; 1.1 acres, 800 ft of lake shoreline, a dock, a pier, a sunset deck, a social pavilion, waterfront hot-tub. It is a private lake experience; nothing really compares - unique!

Destination Keowee
A rustic industrial style Lake Keowee lakefront escape that places you right on a panoramic point in a private cove. Welcome the outdoors in with the 6ft kitchen hinge bar window to the upper deck or enjoy the 6-seat hot tub on lower deck. Deep water dock tie off space is available. Guests enjoy the use of 2 standup paddle boards, and lakeside fire pit (guest provide firewood). Great cove sunsets! 15 minutes to Clemson and 1 min Lighthouse Restaurant. Please read all details prior to booking!

Hartwell Hideaway – Dock, Kayaks & Fire Pit
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Beautiful Lake Keowee Condo with great Amenities
"Boasting lake views, a fully equipped kitchen, and resort-style amenities, this 2-bedroom, 2-bath Salem vacation rental condo in Keowee Key will have you experiencing the true meaning of life on the lake. Cool off with a dip in the community's outdoor pool which sits right next to the marina where you can rent a boat for a day out on the water. Tee up a round of golf on the renovated 18-hole course, walk along the trails of Oconee State Park, or catch a football game at Clemson University!"

Cozy Lake House 5 miles from Clemson w Dock
Only 5 miles from Clemson's campus, this retreat is perfectly situated on almost a full acre. You’ll love the cozy feel, with lots of amenities, including a well stocked kitchen, three-season screened-in porch, & open floor plan. Though the house isn’t directly on the water, our private dock on Hartwell is only a 1-2 min walk away! Nestled between Greenville and the mountains, this home is great for Clemson trips, lake adventures, close night life, restaurants, family entertainment, & more!

Private lake setting close to Clemson University
House is located in a private community yet only 2.5 miles to Death Valley and Clemson. Enjoy a walk down to the lake or relax on the back deck. WIFI is included with access to Hulu and Disney+. Kid friendly as well. Property is also within 1.2 miles of Oconee Airport, 0.7 miles to a dock, 1.5 miles to the grocery store, and less than 1.3 miles to Y beach public parking (avoid game day traffic if you are coming in for football). Close to everything in Oconee, Pickens and Anderson Counties.

Lake Keowee Cabin: Peaceful and Bright
Welcome to Lizard Lodge. Relax in this quaint lake cabin with a mountain home vibe nestled in Northern Seneca on Lake Keowee. Enjoy the serenity of a beautifully modern 3-bedroom, 2.5 bath vacation cabin in a quiet gated cul-de-sac with scenic surroundings. On early mornings you can spot wildlife including deer and wild turkeys. Excellent location on the lake a few hundred feet away from a boat ramp. Come to relax, have fun on the lake or even enjoy a romantic escape.

Lakefront dock *hot tub* Anderson/Clemson king bed
Relax & enjoy the beautiful views of lake Hartwell from the front porch daybed swing, hot tub, or private dock. Sleep in a king size bed wrapped in cool cotton linens, a towel warmer, soaking tub with TV, & a breville espresso maker. Located w/i 10 minutes of many restaurants. Less than 20 min. to downtown Anderson Pendleton or Clemson. This prime location on lake Hartwell is a 10 minute boat ride to Portman Shoals Marina, the Galley restaurant, & Green Pond Landing.

Hartwell Escape 6 mi to Clemson Beautiful views
We recently purchased this gorgeous home on Lake Hartwell, in a secluded cul-de-sac in a quiet neighborhood (6 miles to Clemson..ALL BACKROADS) You will have the entire bottom floor with separate entrance . Enjoy beautiful lake views on the covered porch or from our dock. A Private Neighborhood Boat ramp is 25 feet from our home. Bring your boat, use our dock, space for multiple trailers. Driveway parking. Dogs Welcome! ($25 pet fee/entire stay)

Getaway on Lake Hartwell: Pontoon Rental, Clemson
Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.

Lakeside Cabin ❤ Seneca Treehouse Project
Visit a cozy lakeside cabin at the Seneca Treehouse Project. It is a 550-square-foot handcrafted studio apartment with a king bed, futon, and blowup twin. Check out our garden & food forest across the street from the cabin. Take a picnic and enjoy the lake. Our goal is to provide a relaxing, inspiring, and educational experience. We encourage questions, there are some unique features on this property.

The Majestic Treehouse romantic, luxury retreat
LIVE LIKE KINGS & PLAY LIKE KIDS in this extraordinary, award-winning treehouse. This luxury treehouse was designed by Seth Bolt (from the band NEEDTOBREATHE), who grew up on Bolt Farm. Larry Bolt (Seth's dad), proprietor, Eagle Scout, and licensed custom home builder has been building & remodeling homes for over 40 years in upstate SC. We are 32x Superhosts! Named the Most Popular Airbnb in SC!
Popular amenities for Seneca lake access rentals
Lake access house rentals

New Waterfront House with Big Views & Private Dock

Tee House... waterfront on beautiful Lake Keowee

Lakefront+Near Clemson+Dock+Kayaks+Putting Green

New! The Tiger's Perch- Close to Clemson.

Dujardins Keowee Waterfront Home

Keowee Lakefront Home | Hot Tub, Kayaks, Dock!

Lake House Retreat Near Clemson

Coffee and Kayaks - 5 Bedroom Lakefront Retreat
Lake access apartment rentals

Friendship Lake Apartment

Condo at Lake Keowee

TigerTown Tranquility | Lakeview Condo near Campus

Lake Hartwell - Hartwell Villa 8A

Gameday Getaway on Lake Hartwell - close to campus

"Honeysuckle" Comforts of home in Mt. Wilderness

3BR Ground floor condo - 2.4 Miles to Death Valley

The Sugar Shack on Lake Keowee
Lake access cottage rentals

Waterfront cottage w/deep dock 17 miles to Clemson

The Blue Pine - A Cozy Updated Lakeside Cottage

Cottage on the Lake

South Cove Cottage ~ Lake Keowee

Sunset Cottage Lake Hartwell

Lakefront cottage with a view, near Clemson

Cozy 3 Bedroom Cottage With Beautiful Lake Views!

Keowee Waterfront Lakeside Retreat -Keowee Cottage
Quick stats about vacation rentals with lake access in Seneca

Total vacation rentals
Explore 20 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at G$22,994 GYD per night before taxes and fees

Verified guest reviews
Over 720 verified reviews to help you choose

Family-friendly vacation rentals
20 properties offer extra space & kid-friendly amenities

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
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- Rentals with lake access Oconee County
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- Rentals with lake access United States
- Black Rock Mountain State Park
- Gorges State Park
- Tallulah Gorge State Park
- Table Rock State Park
- Clemson University
- Helen Tubing & Waterpark
- Bell Mountain
- Jump Off Rock
- Bon Secours Wellness Arena
- Anna Ruby Falls
- Chattooga Belle Farm
- Carl Sandburg Home National Historic Site
- Unicoi State Park and Lodge
- Jones Gap State Park
- Devils Fork State Park
- Fred W Symmes Chapel
- Dillard House Restaurant
- DuPont State Forest
- Peace Center
- Falls Park On The Reedy
- Looking Glass Falls
- Paris Mountain State Park
- Georgia Mountain Coaster
- Smithgall Woods State Park




