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Pet-friendly vacation rentals in Seneca

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Seneca

Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

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Top guest favorite
A studio apartment is seen from a corner, featuring a kitchen with orange cabinetry and stainless steel appliances. Two armchairs and a small dining table are positioned in the living area, with a television mounted on the wall. Ample lighting and a neutral color palette are present.
Home in Pendleton
4.88 out of 5 average rating, 114 reviews

Basement apartment in Pendleton w/ sep. entrance

This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Top guest favorite
A cozy bedroom is highlighted by a spacious bed with a patterned blanket. Two bedside lamps provide soft illumination on either side. A wooden dresser is positioned against the wall, and a window allows natural light to fill the space, complemented by cream-colored walls.
Apartment in Seneca
4.94 out of 5 average rating, 178 reviews

Clemson Mom Apartment

Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

Guest favorite
The exterior of a modern camper is displayed, featuring a sleek white exterior with black accents. A set of steps leads to the entrance, and ample surrounding greenery provides a natural backdrop. The driveway is paved, offering easy access.
Camper/RV in Anderson
4.87 out of 5 average rating, 120 reviews

33 Ft Camper perfect for a layover/getaway

Close to Clemson, I- 85, Lake Hartwell, and Anderson. My 2023 Wildwood 28vbxl CAMPER sits in my driveway which is also home to Freedom Fences, a non profit animal rescue. This is a working farm so people are always milling around. Well behaved, housetrained animals allowed but must be crated if left alone. Great spot for Clemson football. 25 minutes to Greenville. 10 minutes from downtown Anderson. Less than 7 miles to Garrison arena. NO Smoking! If you are high maintenance, don't book!

Superhost
A single-story home is presented with a light-colored facade and a covered front porch. The driveway leads to a garage, and neatly trimmed bushes frame the entrance. Tall trees and greenery provide a natural backdrop, enhancing the property's privacy and peaceful setting.
Home in Pendleton
4.89 out of 5 average rating, 207 reviews

Comfort & Convenience Close to Campus

The perfect blend of modern charm and full comfort & convenience just minutes from Clemson, The Pendleton Square and HWY access. You will be sure to have everything you need for your visit. Comfortably sized bedrooms with queen size beds. Spacious living area with cable TV & Netflix. Bright and open kitchen and dining fully equipped for all your cooking needs. Whether you're traveling alone for a little peace & quiet, with friends, or with family... we hope you enjoy your time here!

Top guest favorite
A charming home is presented in a serene neighborhood setting, featuring a well-maintained lawn and flowering shrubs. The exterior showcases a light-colored façade with a welcoming front porch and a spacious driveway leading to a two-car garage.
Home in Seneca
4.99 out of 5 average rating, 225 reviews

The Cozy Cottage

Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

Guest favorite
Tiny home in Pendleton
4.89 out of 5 average rating, 201 reviews

The Rustic Rectangle

Relax at The RR, just 5–15 minutes from Lake Hartwell, Clemson University, Tiger Town shopping, dining, and sunset spots. The space offers a full-bed bedroom, stocked bath, small kitchen, and cozy living area with TV and fireplace. Enjoy the porch, grill, hot tub, outdoor games, and fire pit. Kayaks are available for rent upon request for nearby water access. A peaceful home base perfect for Clemson weekends, lake days, or a quiet getaway.

Top guest favorite
A single-story house with a welcoming porch is surrounded by a manicured lawn. Lush green shrubs and flower beds frame the entrance, complemented by an American flag displayed on the front. The carport is visible to one side, providing additional parking.
Home in Seneca
4.95 out of 5 average rating, 131 reviews

Getaway on Lake Hartwell: Pontoon Rental, Clemson

Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.

Top guest favorite
A bright and spacious kitchen features a central island with a granite countertop, surrounded by blue upholstered chairs. A dining table with wicker chairs is located nearby, and natural light fills the room through sliding glass doors leading to the outdoor area.
Home in Seneca
4.96 out of 5 average rating, 128 reviews

5 Min to Clemson | Large Driveway & Self Check-In

Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Top guest favorite
The exterior of the property is shown, featuring yellow siding complemented by dark shutters on the windows. A single door with glass panels is visible, providing a welcoming entrance. A grassy area is located at the base of the wall, enhancing the outdoor setting.
Guesthouse in Liberty
4.93 out of 5 average rating, 209 reviews

Holly Hideaway! 10 Highway miles to Clemson U!

Holly Hideaway is nestled between Greenville and Clemson, in the small town of Liberty. It's perfect for business travelers, couples, Clemson parents, alumni, and small families. Tiled throughout for cleanliness. Privacy, tranquility, and clean, comfortable accommodations are what we provide. We are 10 minutes from Clemson and 3 miles from SWU. The Hideaway now offers Wi-Fi and Smart TV.

Guest favorite
The exterior of a spacious single-story home features a red metal roof and light-colored siding. A welcoming blue front door is positioned under a small porch, surrounded by green shrubs. A gravel driveway leads up to the house, framed by trees and a clear blue sky.
Home in Central
4.97 out of 5 average rating, 131 reviews

The House on Oak Grove

Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.

Guest favorite
Home in Martin
4.93 out of 5 average rating, 107 reviews

Havenly Lake House w/ Hot Tub & Private Dock!

Get away from the daily hustle bustle with calm & relaxing lakeside waters! Our newly renovated home provides a short, easy walk down to your own private dock in a deep water cove. This is your haven on the lake without the water & road traffic of Hartwell. From inside the home, take in the wide lake views from a screened-in patio overlooking the water.

Top guest favorite
The cabin is softly illuminated by warm lighting, enhancing its inviting exterior. Wooden siding and a covered porch create a rustic charm. Steps lead to the porch, which features potted plants and a welcoming atmosphere for relaxation in nature's embrace.
Guesthouse in Westminster
4.99 out of 5 average rating, 187 reviews

Lit'l Bit O' Heaven- Rocky Top Lodge

Rocky Top Lodge is nestled in the Foothills of the Blue Ridge Mountains and was carefully designed and thoughtfully decorated. All of the décor was hand chosen over a 2 year period. Be sure to check out our sister cabin, The Farmhouse, also listed on Airbnb. Cabins are situated next to each other yet very private.

Popular amenities for Seneca pet-friendly home rentals

When is the best time to visit Seneca?

MonthJanFebMarAprMayJunJulAugSepOctNovDec
Avg. priceG$24,277 GYDG$17,789 GYDG$18,208 GYDG$25,533 GYDG$33,067 GYDG$31,184 GYDG$32,439 GYDG$38,299 GYDG$42,904 GYDG$35,997 GYDG$41,648 GYDG$30,137 GYD
Avg. temp6°C8°C12°C16°C21°C25°C27°C26°C23°C17°C11°C7°C

Quick stats about vacation rentals that are pet-friendly in Seneca

  • Total vacation rentals

    Explore 20 vacation rentals in Seneca

  • Nightly prices starting at

    Seneca vacation rentals start at G$10,464 GYD per night before taxes and fees

  • Verified guest reviews

    Over 1,520 verified reviews to help you choose

  • Family-friendly vacation rentals

    10 properties offer extra space & kid-friendly amenities

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wi-Fi availability

    20 of Seneca vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Seneca rentals

  • 4.9 Average rating

    Seneca stays are highly rated by guests—averaging 4.9 out of 5!