
Pet-friendly vacation rentals in Seneca
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Seneca
Guests agree: these pet-friendly homes are highly rated for location, cleanliness, and more.

Basement apartment in Pendleton w/ sep. entrance
This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Clemson Mom Apartment
Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

33 Ft Camper perfect for a layover/getaway
Close to Clemson, I- 85, Lake Hartwell, and Anderson. My 2023 Wildwood 28vbxl CAMPER sits in my driveway which is also home to Freedom Fences, a non profit animal rescue. This is a working farm so people are always milling around. Well behaved, housetrained animals allowed but must be crated if left alone. Great spot for Clemson football. 25 minutes to Greenville. 10 minutes from downtown Anderson. Less than 7 miles to Garrison arena. NO Smoking! If you are high maintenance, don't book!

Comfort & Convenience Close to Campus
The perfect blend of modern charm and full comfort & convenience just minutes from Clemson, The Pendleton Square and HWY access. You will be sure to have everything you need for your visit. Comfortably sized bedrooms with queen size beds. Spacious living area with cable TV & Netflix. Bright and open kitchen and dining fully equipped for all your cooking needs. Whether you're traveling alone for a little peace & quiet, with friends, or with family... we hope you enjoy your time here!

The Cozy Cottage
Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

The Rustic Rectangle
Relax at The RR, just 5–15 minutes from Lake Hartwell, Clemson University, Tiger Town shopping, dining, and sunset spots. The space offers a full-bed bedroom, stocked bath, small kitchen, and cozy living area with TV and fireplace. Enjoy the porch, grill, hot tub, outdoor games, and fire pit. Kayaks are available for rent upon request for nearby water access. A peaceful home base perfect for Clemson weekends, lake days, or a quiet getaway.

Getaway on Lake Hartwell: Pontoon Rental, Clemson
Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.

5 Min to Clemson | Large Driveway & Self Check-In
Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Holly Hideaway! 10 Highway miles to Clemson U!
Holly Hideaway is nestled between Greenville and Clemson, in the small town of Liberty. It's perfect for business travelers, couples, Clemson parents, alumni, and small families. Tiled throughout for cleanliness. Privacy, tranquility, and clean, comfortable accommodations are what we provide. We are 10 minutes from Clemson and 3 miles from SWU. The Hideaway now offers Wi-Fi and Smart TV.

The House on Oak Grove
Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.

Havenly Lake House w/ Hot Tub & Private Dock!
Get away from the daily hustle bustle with calm & relaxing lakeside waters! Our newly renovated home provides a short, easy walk down to your own private dock in a deep water cove. This is your haven on the lake without the water & road traffic of Hartwell. From inside the home, take in the wide lake views from a screened-in patio overlooking the water.

Lit'l Bit O' Heaven- Rocky Top Lodge
Rocky Top Lodge is nestled in the Foothills of the Blue Ridge Mountains and was carefully designed and thoughtfully decorated. All of the décor was hand chosen over a 2 year period. Be sure to check out our sister cabin, The Farmhouse, also listed on Airbnb. Cabins are situated next to each other yet very private.
Popular amenities for Seneca pet-friendly home rentals
Pet-friendly house rentals

Comfy, cozy duplex apt in old home downtown Easley

Sweet and Cozy Home for Rent

New! Charming 4/2.5 Modern Home in Clemson, SC

Cozy 2 bedroom in Walhalla

No cleaning fee farmhouse lake keowee near Clemson

Vaulted Ceilings & Accent Windows--1 mile from CU

Cozy Modern Home Close Clemson

Peaceful Lake Keowee Waterfront Home ~Near Clemson
Pet-friendly home rentals with a pool

Lakeside Retreat • Hot Tub • Fenced Yard

Lakefront 2BR+/2BA w/ a Dock On Lake Hartwell

Lisa's Lodge

Treetop Cabin w/ firepit + Mountain Stream

Resort Pool & Spa 3BR 3BTH Family Home w Privacy

Lake Keowee Loft Cabin + Walkable Dock Access

Fall Specials | King En-suite | 40’ Deck | 1mile t

Winter fun-Ice skating rink minutes away!
Private, pet-friendly home rentals

Oak Hill Getaway

The Blue Pine - A Cozy Updated Lakeside Cottage

Modern home near Clemson, Keowee

The Farm Cottage

The Landing Spot

Carolina Cottage Retreat

Hartwell Hideway

The Cashiers Cabin
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | G$24,277 GYD | G$17,789 GYD | G$18,208 GYD | G$25,533 GYD | G$33,067 GYD | G$31,184 GYD | G$32,439 GYD | G$38,299 GYD | G$42,904 GYD | G$35,997 GYD | G$41,648 GYD | G$30,137 GYD |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Quick stats about vacation rentals that are pet-friendly in Seneca

Total vacation rentals
Explore 20 vacation rentals in Seneca

Nightly prices starting at
Seneca vacation rentals start at G$10,464 GYD per night before taxes and fees

Verified guest reviews
Over 1,520 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wi-Fi availability
20 of Seneca vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests—averaging 4.9 out of 5!
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- Black Rock Mountain State Park
- Gorges State Park
- Tallulah Gorge State Park
- Ski Sapphire Valley
- Table Rock State Park
- Bell Mountain
- Helen Tubing & Waterpark
- Clemson University
- Jump Off Rock
- Anna Ruby Falls
- Carl Sandburg Home National Historic Site
- Bon Secours Wellness Arena
- DuPont State Forest
- Falls Park On The Reedy
- Devils Fork State Park
- Jones Gap State Park
- Peace Center
- Chattooga Belle Farm
- Fred W Symmes Chapel
- Paris Mountain State Park
- Smithgall Woods State Park
- Looking Glass Falls
- Oconee State Park
- Unicoi State Park and Lodge




