Vacation rentals in Seneca

4.96 out of 5 average rating, 167 reviews

A cozy camper, surrounded by greenery, is partially covered by a metal roof. The wooden deck features a hot tub and seating area, complemented by a hammock hung nearby. A privacy fence stands to the side, providing an inviting outdoor retreat.

Camper/RV in West Union

Hot Tub, Firepit, Projector, No Extra Fees/Chores

Escape to this enchanting bear themed camper, nestled on a cozy one acre wooded lot. While another camper is nearby, a privacy fence creates your own peaceful haven. Soak in the hot tub on the covered deck, with a towel warmer and movie projector adding to the fun. Ideally located between three cities, you’re just minutes from shopping, dining, lakes, waterfalls, and scenic hiking trails. Cap off your evening by the firepit, roasting marshmallows under a starlit sky. Your serene getaway awaits!

4.99 out of 5 average rating, 175 reviews

The cottage exterior displays warm wood siding with large windows allowing natural light. A welcoming front porch features two chairs and a small plant, while a grill stands nearby. Surrounding landscaping creates a serene atmosphere in a private setting.

Cottage in Central

The Wildflower

Enjoy a relaxing experience at this centrally-located spot, away from the hustle and bustle but only 6 min from Clemson (10 min from Clemson University), nestled in the country in a peaceful, safe neighborhood with lots of privacy surrounding. The cottage has a front porch with 2 chairs, a 2 person hammock, grill, and a fire pit (wood is provided) with three lawn chairs. There’s a queen bed and also a CordaRoy beanbag (*bed #2) that opens up to a soft bed that sleeps 1 adult or two children.

4.95 out of 5 average rating, 172 reviews

A cozy bedroom is highlighted by a spacious bed with a patterned blanket. Two bedside lamps provide soft illumination on either side. A wooden dresser is positioned against the wall, and a window allows natural light to fill the space, complemented by cream-colored walls.

Apartment in Seneca

Clemson Mom Apartment

Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

A charming home is presented in a serene neighborhood setting, featuring a well-maintained lawn and flowering shrubs. The exterior showcases a light-colored façade with a welcoming front porch and a spacious driveway leading to a two-car garage.

4.99 out of 5 average rating, 216 reviews

The Cozy Cottage

Beautiful, well-maintained home located in a private subdivision just minutes away from shopping, restaurants, lakes, golf courses, and Clemson University. This home has a fully equipped kitchen for dining in and a back patio for grilling out. The backyard overlooks a peaceful wooded area, providing a serene and private escape. Our home offers the perfect blend of tranquility and convenience. Perfect for getaways, football weekends, graduation, and other Clemson University events!

4.95 out of 5 average rating, 265 reviews

A charming exterior view of the Tiny Treehouse features a bright red roof and wooden siding with a sunflower design. A picnic table sits on the lawn, surrounded by green grass and trees. A lounging area with rocking chairs is nearby, providing a welcoming outdoor space.

Tiny home in West Union

Holliday's Inn Tiny Tree-house

Tiny Treehouse is a ‘container’ house set in a private wooded locale at the foothills of the mountains. Find yourself hiking at Oconee State park or Caesar's Head mountain along with a multitude of waterfalls within our county. 5 minutes from downtown historic Walhalla, 10 minutes to city of Seneca, and 20 minutes from Clemson University where tailgaters unite before the big football game! Explore the artistic venues and cultural scenes of Greenville just an hour away!

4.97 out of 5 average rating, 125 reviews

The interior space features wooden paneling and a high ceiling, with a spacious bed adorned with a striped blanket. The kitchenette, visible in the background, includes dark cabinets and modern appliances. Soft lighting enhances the cozy ambiance of the room.

Tiny home in Salem

The Meadow #4

Take it easy at this unique and tranquil getaway. We ask you to not bring pets due to allergies. We are 4 miles from Fall Creek Landing on Lake Keowee and 8 miles from Lake Jocassee Devils Fork StatePark. The bed is comfortable and the futon is also great for that extra person or children. Grab a drink or a cup of coffee and Sit on the porch or relax in the hammock. Hike our many waterfalls. Self check in anytime after 2:00 pm. Check out is 11:00. Am

4.97 out of 5 average rating, 583 reviews

The exterior of a modern tiny house is depicted, featuring a dark blue façade and large windows allowing natural light to fill the interior. The covered porch is accessible from the gravel pathway, and greenery surrounds the property, enhancing the wooded setting.

Cottage in Westminster

Tiny house

BRAND NEW 490 sq ft tiny house/cottage nestled in the woods in a country setting. Complete with a queen bedroom, a twin/day bed and then a queen bed in loft ( comfortably sleeps 4 adults and one child). We are conveniently located 10 miles from I-85 exit 1 on S Hwy 11. 20 minutes from Clemson, 8 minutes from Seneca, and just a short drive to many hiking trails, lakes and parks in the beautiful foothills of the Blue Ridge mountains.

4.93 out of 5 average rating, 119 reviews

The charming house, surrounded by lush greenery, features a screened-in front porch that invites relaxation. A flag gently flutters on the porch, while well-maintained landscaping frames the entrance. Large trees provide ample shade, enhancing the tranquil outdoor environment.

Home in Westminster

Shady Rest

As you enter the screened in front porch you will instantly relax, experience a peaceful and quiet tree lined front yard. The house has plenty of shade and old oaks, built in 1935 has the charm of visiting great grandmother’s farm house without the wallpaper. Large side deck with grill, hot tub and plenty of shaded sitting. Side yard has a fire pit for evening campfires and roasting marshmallows. The house has an open floor plan.

4.96 out of 5 average rating, 218 reviews

A charming tiny house is set amidst wooded surroundings, featuring a welcoming entrance with a white door and a light-colored roof. Two white chairs and a small table are positioned on a wooden porch, complemented by a grill nearby. Lush greenery enhances the tranquil setting.

Tiny home in Seneca

Windmill Cottage

You’ll treasure your time at this cute little cottage. It is 295 sq feet and was built in 2023 at the edge of the woods on our property. It has a full kitchen, bedroom with a queen bed, bathroom and living room. It is perfect for one or two people, for either a quiet get-away in the country or for someone who is in town for work and is looking for a more extended stay. We offer discounts for weekly/monthly stays!

A bright and spacious kitchen features a central island with a granite countertop, surrounded by blue upholstered chairs. A dining table with wicker chairs is located nearby, and natural light fills the room through sliding glass doors leading to the outdoor area.

4.96 out of 5 average rating, 109 reviews

Cozy 3 Br Family Home • 5 min to Clemson Campus

Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

4.96 out of 5 average rating, 244 reviews

A charming cottage is nestled among trees, featuring a red exterior and a covered porch. Two Adirondack chairs invite relaxation near the entrance. A simple stone pathway leads to the door, while autumn leaves cover the ground, enhancing the natural setting.

Cottage in Townville

The Little Cottage on Pine/20 minutes to Clemson

The Cottage was created for the purpose of having a beautiful place to host our out-of-town family and friends. We chose to make it available for guests like you as well. It is tucked away in the quiet countryside of Upstate SC. Enjoy the peaceful farmland, your morning cup of coffee on the front porch, the nearby lakes and a short drive to downtown Clemson. Perfect for a relaxing weekend getaway.

4.93 out of 5 average rating, 201 reviews

The exterior of the property is shown, featuring yellow siding complemented by dark shutters on the windows. A single door with glass panels is visible, providing a welcoming entrance. A grassy area is located at the base of the wall, enhancing the outdoor setting.

Guesthouse in Liberty

Holly Hideaway! 10 Highway miles to Clemson U!

Holly Hideaway is nestled between Greenville and Clemson, in the small town of Liberty. It's perfect for business travelers, couples, Clemson parents, alumni, and small families. Tiled throughout for cleanliness. Privacy, tranquility, and clean, comfortable accommodations are what we provide. We are 10 minutes from Clemson and 3 miles from SWU. The Hideaway now offers Wi-Fi and Smart TV.

Vacation rentals for every style

Get the amount of space that is right for you

Cabins

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Stylish accommodations with great services and amenities

Popular amenities for Seneca vacation rentals

Gym

BBQ grill

Laptop-friendly workspace

Wifi

Air conditioning

Other great vacation rentals in Seneca

5 out of 5 average rating, 83 reviews

A charming cabin is nestled among trees, featuring a sloped roof and front porch. Two green chairs are placed on a sandy pathway leading to the entrance, inviting relaxation in a serene outdoor setting.

Tiny home in Seneca

Oak Hill Getaway

4.89 out of 5 average rating, 329 reviews

A geodesic dome is illuminated from within, set against a backdrop of trees. An adjacent wooden structure features outdoor seating under string lights, creating a welcoming atmosphere for relaxation. The natural environment is highlighted, emphasizing the dome's unique design.

Dome in Salem

G.O.A.T. Geodome: Farm Animals, Hot Tub, Zip Line

Superhost

A swinging wicker chair is positioned on a wooden dock, overlooking a calm lake. Soft clouds drift across a bright blue sky, and lush green trees line the water’s edge, contributing to a serene outdoor setting.

4.79 out of 5 average rating, 28 reviews

Cozy Clemson Lake Hartwell Getaway with Dock

5 out of 5 average rating, 41 reviews

A cozy sleeping area features a spacious bed with white linens and a textured blanket draped across the foot. Natural light enters through a window adorned with a bamboo shade, and a wooden shelf displays decorative items and plants.

Treehouse in Seneca

Treehouse at Keowee Hollow

5 out of 5 average rating, 30 reviews

A custom-built cottage is nestled in a natural setting, surrounded by greenery. The structure features warm lighting emanating from windows, complemented by a spacious porch. The surrounding lawn offers ample space, framed by trees that enhance the peaceful atmosphere.

Cabin in Seneca

NEW Creekside Cottage w/ Hot Tub, 12 mi to Clemson

5 out of 5 average rating, 42 reviews

An inviting entrance features a wooden porch with decorative flowers and a bench. A staircase leads to the upper-level apartment, while an American flag adds a patriotic touch. Natural light illuminates the space, creating a welcoming ambiance.

Guesthouse in Seneca

Hartwell Hideway

4.98 out of 5 average rating, 94 reviews

A vintage camper is positioned under a canopy, offering protection from the elements. An outdoor seating area features a table with a small grill nearby. A stack of firewood is neatly organized beside a fire pit, surrounded by comfortable chairs on a textured surface.

Camper/RV in West Union

Nordic Highlands Retreat, 30' Vintage Camper

A charming cottage is surrounded by lush greenery and tall trees, featuring a welcoming front porch with seating. The exterior is clad in grey siding and highlights stylish architectural design elements. A gravel driveway leads up to the house, emphasizing its peaceful and private setting.