
Guesthouse vacation rentals in San Diego
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Diego
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego guesthouse rentals
Family-friendly guest house rentals

Lovely Guesthouse in garden setting

San Diego Shangri-La

Spacious, private Mt. Helix country style studio

Beach Rock Retreat - Private Encinitas Guesthouse

New Guest House - North Park

Fletcher Hills - modern 1 BR.Easy, no step access.

OB studio, ocean views, hot tub & garage parking!

Cozy Cottage 1/2 mile to North Park close to dtwn
Guest house rentals with a patio

Garden Casita

Adorable cottage in Talmadge

Gorgeous Guesthouse Poway w/Private Yard

Private 1 BR Paradise retreat

Da Hui Hut - La Mesa’s best view and spa

Downtown Cottage Minutes to Gaslamp & Petco Park

Cozy Urban Casita! Near Zoo, Gaslamp and Coronado

Cozy, Quiet and Private Backyard Studio Escape
Guest house rentals with a washer and dryer

Stunning Guest House 15 min. from Zoo, Downtown

The Happy Family * 2 playhouses near SDSU!

South Mission Beach Zen-Like Studio

Clean Cozy Private Guesthouse - Central San Diego

Early 1900's Carriage House w/Views

Ocean/Lagoon View/New Luxury Casita /Walk To Beach

Private San Diego Guest House - Beautiful View

Enjoy North Park at Comfy & Chic Bungalow Retreat
Quick stats about guesthouse rentals in San Diego
Total rentals
1K properties
Total number of reviews
101K reviews
Family-friendly rentals
140 properties are a good fit for families
Pet-friendly rentals
240 properties allow pets
Rentals with a pool
90 properties have a pool
Rentals with dedicated workspaces
540 properties have a dedicated workspace
Destinations to explore
- La Joya Vacation rentals
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- Rosarito Beach
- Oceanside City Beach
- Belmont Park
- Tijuana Beach
- Torrey Pines State Beach
- Pacific Beach
- Coronado Beach
- SeaWorld San Diego
- La Misión Beach
- Coronado Shores Beach
- Oceanside Harbor
- University of California San Diego
- LEGOLAND California
- Black's Beach
- San Diego Zoo Safari Park
- Balboa Park
- Liberty Station
- Sesame Place San Diego
- Moonlight Beach
- Playas Los Buenos
- USS Midway Museum
- Law Street Beach
- Hillcrest
- Torrey Pines Golf Course
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