
Guesthouse vacation rentals in San Diego County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Diego County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Santorini-Inspired Cottage w/ Hot Tub + Views
*CHECK OUT OUR OTHER AIRBNB* Travel 16 steps up a Greek-inspired curving stairway with 2-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina. With spectacular views, step onto the balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. European-inspired design & details, it'll be hard to believe you’re still in San Diego!

Hilltop cabin retreat with lake & mountain views
Rustic hilltop cabin overlooking Lake Hodges. Surrounded by open canyons & mountains, you will feel like you're a million miles away from everything as you take in the views from the cabin, deck or the outside shower, swim in the saltwater pool, or relax by the fire bowl. A short walk to lake with boating, fishing & miles of hiking/mountain biking trails. Property offers swimming pool, fire bowl, and shaded arbor. SD Zoo Safari Park, wineries, breweries, & ocean beaches all within easy reach.

Private 1 BR Paradise retreat
Private, yet central. It is your exclusive paradise retreat to enjoy from your spacious 1 bedroom guest house located on the lower level of our home. Hang out in the expansive and private backyard with pool, different sitting areas and covered BBQ room. Or maybe a workout in the gym. Centrally located in the Village of La mesa. Just a 1/4 mile jaunt into the quaint village with its numerous assortments of dining options, stores and trolley station. Freeway close to beaches, downtown and airport

Central & Serene Secret Garden Guesthouse
My cozy & stylish Garden Guesthouse features colorful decor that gives a fun, relaxed vibe. Relax in style inside or outside in my peaceful garden w a cup of coffee, or glass of wine. I love to say a hi to my guests yet your privacy is #1. Reach me via Airbnb app if I can help! Kensington is a central, 1920’s historic neighborhood w shops & great local eateries. Close to downtown, Gaslamp, Zoo, airport, beaches, Balboa Park. Bus stop, & trolley nearby. Reserved off street parking space too!

Loft Cabin •SoakTub•Cinema•View +Zoo pkg add-on
Tucked away in one of San Diego’s scenic hillside canyons, this cozy tiny cabin is immersed in nature, yet just a short drive outside the city. From your private patio, take in sweeping city and sunset views while listening to the sounds of quail and hummingbirds. Modern comforts incl mini split A/C & heat, fast wifi and off-street parking. Unplug & unwind in the Outdoor Soaking Tub or Rain Shower, and cap off the evening with your very own outdoor movie experience at “Cinema Under the Stars”

Infinity Poolside Apt. In San Diego Wine Country
168 Perfect 5.0 Reviews-Amazing views, peaceful and beautiful space in a wine country setting. A perfect setting to celebrate a special occasion and create memories. Amazing sweeping views of wine country, golf course and mountains on the 14th green of a golf course with full access to the estate pool, spa, covered parking, EV charger w/private European park. Large luxury suite with a Kitchen, Sitting Room, Bathroom, Steam shower/Sauna and bedroom with luxurious robes, linens and towels.

Betty- Guesthouse near CBX & San Ysidro border
This comfy studio located in San Diego is the perfect spot for a quiet & cozy weekend retreat. Inside is bright & inviting with stylish spacious studio, private entrance from side gate, private patio with bbq & hanging hammocks; driveway parking spot & plenty of street parking! The view from the patio is very relaxing, making it the perfect weekend get away. Centrally located in a quiet & peaceful area within 5 minutes away from Plaza Las Americas & 10 minutes away from the CBX.

Retreat house. Nature, Hot Tub, Views!
Expansive spaces, ocean views, birds singing, and larger than life granite boulders all come together to offer something that feels like magic. More like a national park than a home, we've found that guests enjoy the pace and peaceful surroundings and spend most of their visit without leaving. That being said, if you're feeling more exploratory, there are many options within a short drive including hiking, wine tasting, horseback riding, fishing, and even sky-diving.

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV
This is the perfect Guest House with a salted & heated pool & hot tub. We are located in a super quiet & very safe neighborhood in beautiful San Diego, 15 minutes drive to Downtown, La Jolla, Beaches, Zoo, Sea World & Convention Center. Hike next door at Mission Trails & Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo and top quality finishes await you inside. Everything you need for memorable vacation! No smoking or vaping on the property.

New Tranquil Barn Retreat on a Peaceful Half Acre
The Buena Vista barn is a clean, quiet, and upgraded detached barn in Vista with everything you need for a peaceful and comfortable stay! Only 10 minutes to downtown Vista, you'll find great restaurants, breweries, shops, and a movie theater. Points of interest: • Downtown Vista: 10 minutes • Cal State San Marcos: 15-17 minutes • Beach: 20 minutes • Legoland: 22 minutes • Temecula and Wine Tasting: 30-40 minutes • Sea World: 47 minutes

Private Casita on 6-Acres with VIEWS
Amazing views! Get away from it all. Private guest house on a 6-acre avocado grove with a separate driveway and access. Enjoy being surrounded by nature. Gaze at the breathtaking views while sipping on your morning coffee or evening wine. BBQ in the afternoons and sit around the firepit table on the deck for the ultimate relaxing getaway. Have fun with family and friends playing ping-pong, air hockey, cornhole and more!

Mountain View Retreat in Gated Estate (Hot Tub)
Perched above a canyon with spectacular panoramic mountain views, this private guest house is a secluded retreat in one of San Diego’s most eclectic and desirable neighborhoods less than 6 miles from the Downtown San Diego airport. Enjoy a fully equipped kitchen, luxe king size bed and dual sliding glass doors that open to an expansive deck with patio seating, private hot tub and BBQ area.
Popular amenities for San Diego County guesthouse rentals
Family-friendly guest house rentals

Beautiful Private Guest Suite

Studio Chalet in the Hills of Vista

Detached, Small Private Studio, PET friendly!

Secluded Casita in Wine Region

Casita w/Private Pool, King Bed, Full Kitchen!

Brand New Modern North Park View Apartment

Rose Guest Private Suite. Central location!

Beautiful Cottage in Central SD!
Guest house rentals with a patio

Adorable cottage in Talmadge

Free Bikes. 5 min walk to Windensea Beach La Jolla

Gorgeous Guesthouse Poway w/Private Yard

Private Balcony! Sunset & SunriseVIEWS!

Breathtaking Ocean Views-Sunset Cliffs/Ocean Beach

SDCannaBnB #1 *420 *parking *dog-friendly *hot tub

SDSU Central Cozy Casita | Fast Wi-Fi | Walkable

Cozy Country Cottage with increíble veiws
Guest house rentals with a washer and dryer

Lovely Guesthouse in garden setting

Stunning Guest House 15 min. from Zoo, Downtown

Cozy Detached Casita w/AC & heat

Carrie’s North Park Casita, in Heart of San Diego

South Mission Beach Zen-Like Studio

BEAUTIFUL Private Studio

Beach Rock Retreat - Private Encinitas Guesthouse

Fletcher Hills - modern 1 BR.Easy, no step access.
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- Oceanside City Beach
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