
Boutique hotels in Panama
Find and book unique boutique hotels on Airbnb
Top-rated boutique hotels in Panama
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

Villa Alejandro - Tastefully Furnished Room
Just 5 minutes walk to centre, calmly situated and close to town located in an extraordinary mansion. Lovely furnished bedroom (King-Size/Orthopedic mattress) with private bathroom and walk-in closet . Affectionately decorated living room with spectacular view to the Boquete valley by large windows and large, full equipped kitchen can be shared with other guests. Lot of space for dining/reading in the living room. Lovely garden and terrace can be used. Gated carport. Fast WiFi, CableTV, Netflix

Treetop views of the Pacific in a boutique cabaña
No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Villa Coco King Room
Villa Coco is a beautiful boutique hotel in Santa Catalina, only footsteps away of the world known surf break “La Punta” and Unesco world heritage Coiba island. The carefully designed cabañas, provide a space of tranquility and a sense of timelessness. Unwind in the hammocks and canvas chairs on your private terrace, dwell on reading your favorite book or sip on a cool drink from the bar. Our Restaurant “Ai Mamita” offers different kinds of meat, fresh seafood and other tasty delights.

Casa Florecer- bungalow at the edge of the sea
Welcome to Casa Florecer, a bungalow at the edge of the sea. Your space is simple and elegant. A studio apartment with plenty of room to enjoy a quiet & peaceful time on the island. The bungalow boasts a screened in porch, gorgeous views, and pristine coral reef for your front yard. All stays include a locally sourced vegetarian breakfast served in our over the water eatery, Juntos. For fun closer to home: we have snorkel gear, paddle boards, and yoga mats available for your enjoyment.

B) Beach, surf and Relax with King size bed
Manglar Lodge is a cozy beach Airbnb in the surf town of El Palmar, San Carlos, on Panama’s Pacific coast. Surrounded by nature, it’s the perfect place to relax and enjoy the coastal vibe. Guests can unwind in comfortable rooms with Wi-Fi, A/C, cable TV, private bathroom, and a welcoming atmosphere. We’re just a few hundred meters from the beach and several great surf spots. Please note: the room is on the first floor and requires walking up stairs **No pets allowed **

Boutique Inn_The Hill 1_Private Entry_Sea View_16+
The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 1 was designed as a boutique hotel room with stunning ocean view from private deck, separated private entry and communal kitchen on side.

Palmas Room - Tranquil Space with King Bed
This 2 person room is wonderful for calm and relaxation. With beautiful rustic decor, a comfortable king bed, A/C, hot/cold water, mini fridge, smart tv (ready for your streaming login), this room will allow you to wash away the salt and sand and relax after fun days surfing and laying on the beach. *Additional guest, available to kids up to 12 years old.* *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host.*

Medieval Suite Nature & Art
La Corte del Re is a tourist structure composed of a set of suites with a medieval theme (macabre art) immersed in the woods where art and nature merge in the heart of Anton's Valley. A few steps from the center are equipped with all comforts and have a park, pool, lake with Koi carpe and parking. They don't have a kitchen. Guests can enjoy a Muay Thai, jiu-jitsu and MMA academy.

Private rooms Sofia's B&B Hostal Boutique
Boutique hostel-style accommodation, we have 7 comfortable private rooms with bathroom, for a total capacity of 18 guests. The rate shown by Airbnb for your reservation is for 2 guests per room, i.e., guests will need to share beds and/or rooms. If you require a special room layout for your group, please contact the host first, as the rate may vary.

Villa la Fortuna, Altos del Maria, Panama
Discover the charm and tranquility where personalized service meets rustic comfort. Wake up to stunning views of nature, indulge in local flavors at breakfast, and unwind in our cozy lounge area. Our friendly hosts are always ready to share tips and recommendations for exploring the area. Experience a unique and memorable stay at our special place.

Blue Room for 2 at Casa Lassini - Oceanfront!
Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.

The Corner Suite #110 | La Résidence Panamá
Contemporary comfort for the modern traveler. This 35–37 m² suite features a king-size bed, full kitchen, washer/dryer, Coffe machine, and A/C — designed with thoughtful touches to make you feel at home.
Popular amenities for Panama boutique hotels
Family-friendly boutique hotels

Rancho Cabaña- Private Porch, Loft, 1 min to beach

Family & Group Bungalow

Ciel Y Miel, Boutique Hotel on the Caribbean Coast

Beautiful loft #5 - kingsize bed

Near bus station and downtown in David, Chiriqui

Agradecer: Surf lover's dream

Yellow Room for 4 at Casa Lassini - Oceanfront!

Amanecer : Delicious Included Breakfast
Boutique hotels with a patio

Charming 1-Bedroom Beachfront Hotel With Pool

Suite Room in the ORHO Hotel

Tranquil Ocean View Cottage At Seagull Cove Resort

Eshel Panama Suites, Atlantic suite 04

Over the Sea Turtle Mini Cabin with Veranda

Corcho rooms #2 - king room with balconies

Standard Room - Hotel El Huésped

Deluxe Double Room with Balcony
Other boutique hotel vacation rentals

La Residencia - Colibri Room

Charming Hotel in Casco Viejo Santa Ana Deluxe

Vida Lotus Jungle Room near Panama City

The City Suite #208 | La Résidence Panamá

Villa Coco Jungle Villa

Panama’s best kept secret: Queen 1 at Vida Lotus

Playa Room - First floor family space, ocean views

Entire place Sofia's B&B Hostal Boutique
Destinations to explore
- Rentals with breakfast Panama
- Beach condo rentals Panama
- Rentals with pools Panama
- Rentals with a sauna Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Nature eco lodge rentals Panama
- Pet-friendly rentals Panama
- Rentals with an accessible height bed Panama
- Smoking-friendly rentals Panama
- Rentals with beach access Panama
- Vacation home rentals Panama
- Townhouse rentals Panama
- Apartment rentals Panama
- Dome rentals Panama
- Cottage rentals Panama
- Villa rentals Panama
- Boat rentals Panama
- Tiny house rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- House rentals Panama
- Farmstay rentals Panama
- Rentals with a home theater Panama
- Beach house rentals Panama
- Rentals with a fireplace Panama
- Shipping container rentals Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Condo rentals Panama
- Loft rentals Panama
- Rentals with a fire pit Panama
- Rentals with a hot tub Panama
- Island rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Waterfront rentals Panama
- Rentals with a patio Panama
- Bed and breakfasts Panama
- Treehouse rentals Panama
- Family-friendly rentals Panama
- Chalet rentals Panama
- Fitness-friendly rentals Panama
- Tent rentals Panama
- Bungalow rentals Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Rentals with lake access Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Lakehouse rentals Panama




