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Vacation rentals in Panama City

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Quick stats about vacation rentals in Panama City

  • Total vacation rentals

    Explore 5,590 vacation rentals in Panama City

  • Verified guest reviews

    Over 149,670 verified reviews to help you choose

  • Family-friendly vacation rentals

    1,780 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 1,940 rentals that welcome pets

  • Vacation rentals with a pool

    2,960 properties feature pools

  • Rentals with dedicated workspaces

    3,570 properties have a dedicated workspace

  • Wi-Fi availability

    5,430 of Panama City vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Self check-in, Gym, and BBQ grill across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City's top spots, include Miraflores Locks, Museo de Arte Contemporáneo, and Santo Tomas (Panama Metro)

Top-rated vacation rentals in Panama City

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern living area features a light-colored sofa adorned with colorful cushions. A round coffee table sits on a textured rug, while a dining table for six is visible in the background. Large windows present striking views of the city skyline.
Apartment in San Francisco

Luxury apt in Panama City 2 Rooms 3 Baths

El edificio Wanders by yoo esta ubicado en el corazón de la ciudad, es un proyecto fuera de serie donde cada rincón tiene una historia que contar. Recepción 24/7, muchas areas de esparcimiento, estación de hidratación. En las afueras del lobby tenemos la Cafetería cafe con teclas y un restaurante de Carnes Popino. En el area social servicio de barra en la piscinas, parque de niños, sala de juegos con pantallas en e l techo baños, salon de eventos, cocina para eventos, gym full equipado y más

FamilyLocationView

5.0 out of 5 average rating, 87 reviews
Top guest favorite
Condo in Bella Vista

Modern Stay | Prime Location | Pool, Rooftop & Gym

Enjoy a spacious, modern apartment with a standing balcony offering beautiful city and mountain views, right in vibrant, local Panama City on Calle 50. Prime location near the iconic Tornillo Building Walk to the Metro, Cinta Costera, Panama Bay, restaurants, bars, coffee shops, local eateries, and supermarkets Enjoy Wi-Fi, Smart TV, parking, pool, gym, workspace, plus an on-site restaurant, coffee shop, and rooftop bar with breathtaking 360° city views Great location & everything close by!

ValueFamilyCheck-in

4.98 out of 5 average rating, 108 reviews
Superhost
An indoor garden is showcased, featuring lush greenery and soft lighting. A glass roof allows natural light to illuminate the space, which is accented by warm-toned stone walls. Two stylish chairs are positioned nearby, creating a comfortable seating area.
Condo in San Felipe

CASA SAEMA -PRESTIGIOSO ATICO DUPLEX CON TERRAZAS

Espectacular ático Duplex en Panamá Casco antiguo, de 265 M2 con balcones, terrazas privadas exterior, cuenta con una salón jardín interior, un comedor, 3 hab. (+ sofá cama en studio), recientemente reformado con concepto Loft, diseño exclusivo único y confortable, en la mejor zona del Casco viejo, perfecto para relajarse y desconectar, cocina , lavavajilla, sala con lavadora. piscina compartida, asc, portero 24-7, (la piscina no esta adaptada para niños), gran variedad de ocio en la zona.

ValueFamilyLayout

4.88 out of 5 average rating, 150 reviews
Superhost
Apartment in Panama City

New Flat with Ocean + City Views

Brand new apartment in a high rise in the middle of downtown Panama. Very centrally located. Two fully furnished rooms and fully equiped kitchen. Gorgeous views of the city and Pacific ocean. Guests will have access to all the building's amenities such as a pool, gym, coworking space and game room. 15 minutes walking distance to Casco Viejo. 5 minute walking distance to Mercado de Mariscos, Cinta Costera and to the 5 de Mayo Metro Station. Airport Pickup and Dropoff Services Also Available.

FamilyValueCheck-in

4.78 out of 5 average rating, 125 reviews
Top guest favorite
A cozy living area features a bright yellow armchair beside a sleek media console. A modern television is mounted above the console, which displays green foliage. The floor is adorned with a patterned rug, while the textured stone wall adds a rustic charm to the space.
Place to stay in San Felipe

Loft en Casco Antiguo, Joya Colonial

Bienvenidos a un espacio donde la historia, el diseño y la comodidad se fusionan en uno de los barrios más emblemáticos de Panamá. Este apartamento, ubicado en el corazón del Casco Antiguo, te sumerge en la rica cultura y arquitectura colonial, mientras te ofrece todas las comodidades modernas para una estancia inolvidable. ✔ Espacioso ✔ Diseño clásico-moderno ✔ Cocina equipada ✔ Balcón privado ✔ Habitación principal de ensueño ✔ WiFi de alta velocidad y Smart TV ✔ Ubicación inmejorable

FamilyValueParking

4.95 out of 5 average rating, 104 reviews
Top guest favorite
The private outdoor pool is set against a backdrop of lush greenery and the home's elegant architecture. Comfortable seating arrangements are positioned nearby on the pool deck, inviting relaxation. Large windows reflect natural light, enhancing the spaciousness of the surrounding area.
Villa in San Francisco

Spacious 6BR House w/ Pool, Gym & King Beds

Enjoy a spacious private home in the heart of Punta Paitilla, one of Panama City’s most central neighborhoods. Perfect for families and groups, the house features 6 bedrooms, 5.5 bathrooms, 9 beds, a private pool, and plenty of space to relax, comfortably accommodating up to 17 guests. Walk to supermarkets, restaurants, and nearby synagogues, or reach Multiplaza and other popular areas of the city within minutes. A comfortable and convenient home base for enjoying Panama City together.

ValueFamilyPets

4.98 out of 5 average rating, 120 reviews
Superhost
A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.
Apartment in Bella Vista

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

LocationValueQuiet

4.91 out of 5 average rating, 332 reviews
Guest favorite
A spacious living area features light wood flooring and a modern open kitchen. Two light-colored sofas surround a marble coffee table, while a dining area with a stylish table sits nearby. A spiral staircase leads to the upper level, and decorative artwork adorns the walls.
Loft in San Felipe

Loft 3b Casco Antiguo Best! Son 150 m2 (492 feet)

Sumérgete en el encanto histórico y la elegancia moderna de nuestro loft de 3 recámaras y 150 m2, en el corazón del Casco Antiguo. Con pisos de madera que irradian calidez y una cocina moderna de diseño abierto ideal para compartir, este espacio garantiza unas vacaciones memorables. Situado en la Avenida A, te encontrarás a solo unos pasos de exquisitos restaurantes, museos, iglesias coloniales y los codiciados rooftops del Casco, convirtiendo cada día en una aventura.

LocationValueBeach

4.93 out of 5 average rating, 126 reviews
Top guest favorite
A bright and airy living space features large floor-to-ceiling windows offering city views. Sleek marble floors complement minimalist furnishings, including two neutral sofas and a stylish coffee table. An open kitchen area is visible in the background, enhancing the overall modern design.
Apartment in Bella Vista

Unique Luxury 3-story Loft at the Yoo

Experience the luxury of a world renowned Philippe Starck designed building. Our 3-bedroom sanctuary is a unique 3-story loft that boasts breathtaking city views, an open-plan kitchen, sleek marble floors, and premium amenities. Steps away from Panama City’s premier attractions, shopping, and dining. Dive into top-tier amenities: a pristine pool, state-of-the-art gym, relaxing spa, and three of the best restaurants in the city! Embrace Panama in unmatched style.

FamilyLocationQuiet

4.96 out of 5 average rating, 89 reviews
Top guest favorite
A spacious living area features a combination of modern and vintage furnishings. A large turquoise sofa and a floral chaise lounge are complemented by a round coffee table and a green wooden chair. Exposed stone walls and large windows with blue accents create a warm ambiance.
Apartment in San Felipe

The apartment of a legendary Panamanian footballer

Location is everything – just steps away from the city’s best restaurants, bars, stunning churches, and fascinating museums. Explore the historic district on foot while enjoying the comfort of a stylish apartment featuring: • A spectacular balcony with beautiful views • A fully equipped kitchen • 1.5 bathrooms • Cozy beds that make you feel right at home • Surrounded by iconic calicanto stone walls that reflect the charm of Panama’s colonial past.

FamilyLocationCheckout

4.99 out of 5 average rating, 208 reviews
Guest favorite
Apartment in Panama City

Ocean View | Rooftop Pool | Luxury Stay

Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.

LocationFamilyDecor

4.97 out of 5 average rating, 97 reviews
Guest favorite
Apartment in Bella Vista

Luxury 2BR at Yoo | Ocean & Skyline Views

✔️SuperAnfitrión Verificado! 🌅 Despierta con una impresionante vista al mar en la exclusiva Cinta Costera. Vive una experiencia única en este apartamento moderno y luminoso, con balcón frente al océano. Relájate en la piscina con vista infinita, entrena en el gimnasio o disfruta de la tranquilidad de Panamá. Cerca de restaurantes, centros comerciales y atracciones turísticas. Ideal para escapadas románticas o viajes de descanso.

FamilyLocationCondition

4.82 out of 5 average rating, 33 reviews

Popular amenities for Panama City vacation rentals

Self check-inGymBBQ grillLaptop-friendly workspaceWifi

Stay near Panama City's top sights

Tocumen International Airport

19 locals recommend

Multiplaza

298 locals recommend

Miraflores Locks

278 locals recommend

Albrook Mall

226 locals recommend

Biomuseo

182 locals recommend

Old Panama

157 locals recommend

Homes in Panama City

Guest favorite
An inviting seating area features a modern sectional sofa with plush cushions arranged in an L-shape. A wooden coffee table rests in front, complemented by indoor plants placed nearby, enhancing the tranquil space.
Home in San Felipe

Maravillosa Casa con Terraza y Vista Al Mar

FamilyLocationCleanliness

4.88 out of 5 average rating, 104 reviews
Top guest favorite
The image showcases the exterior of a two-story house, framed by lush greenery. Sunlight filters through trees, highlighting the white façade and green shutters. A covered area is visible at the front, along with a gated fence that adds security to the property.
Home in Panama City

3BR Home in Ancon Hill - Urban Oasis

ValueLocationAmenities

4.9 out of 5 average rating, 117 reviews
Superhost
The exterior of a two-story residence is shown, featuring a classic design with a stone façade and wooden accents. Lush greenery surrounds the entrance, where steps lead to the upper level. Two friendly dogs can be seen in the foreground, adding a welcoming touch to the scene.
Home in Panama City

Central|Confort|surrounded by nature|Wifi|parking

FamilyLocationParks

4.84 out of 5 average rating, 118 reviews
Guest favorite
Home in Panama City

Estudio Privado a 10 Min del Aeropuerto !

FamilyLocationWalkability

4.94 out of 5 average rating, 444 reviews
Top guest favorite
A spacious living and dining area is depicted, featuring a blue sectional sofa with yellow accent pillows. A glass dining table with yellow placemats and black chairs is shown. Natural light enters through windows, revealing a glimpse of greenery outside.
Home in San Francisco

Spacious Panama House in the 'heart of the city'

FamilyLocationCheckout

4.84 out of 5 average rating, 128 reviews
Guest favorite
A stone pathway leads through lush tropical foliage toward a welcoming entrance. Tall trees and vibrant greenery frame the path, creating a serene approach to the property, which is partially visible in the background, surrounded by nature's tranquility.
Home in Panama City

Mountain Retreat

LocationFamilyPool

4.97 out of 5 average rating, 93 reviews
Superhost
Home in San Miguelito

Casa-confort-cercaacostadeleste-familia

LocationFamilyAmenities

5.0 out of 5 average rating, 4 reviews
Guest favorite
Home in Panama City

La Casa de la Cascada tiene bbq, pin pon, gym

FamilyLocationOutdoor spaces

4.95 out of 5 average rating, 44 reviews

Other great vacation rentals in Panama City

Top guest favorite
Apartment in Bella Vista

“Modernidad y Confort en la Ciudad”

ValueFamilyComfort

4.97 out of 5 average rating, 86 reviews
Guest favorite
Apartment in Panama City

Balboa Avenue Sky Suites

LocationValueView

4.92 out of 5 average rating, 64 reviews
Guest favorite
Apartment in Panama City

Vista al Mar Panamá City

LocationAccuracyCondition

4.94 out of 5 average rating, 17 reviews
Guest favorite
A spacious balcony features clear glass railings, offering unobstructed views of the coastline and the city. The turquoise water reflects the skyline and boats moored in the harbor. An expansive bay curves into the distance, with colorful buildings lining the water's edge.
Apartment in Panama City

Apartamento Balcón Vista al Mar Panamá City

ValueLocationIndoor spaces

4.92 out of 5 average rating, 88 reviews
Top guest favorite
Apartment in San Felipe

Luxury Centric 2BR Apartment in Casco Viejo

ValueLocationIndoor spaces

4.97 out of 5 average rating, 38 reviews
Guest favorite
A rooftop terrace features a small plunge pool surrounded by tropical plants. A child is seen enjoying the water, while the ocean and skyline are visible in the background. Soft seating and vibrant colors enhance the relaxing atmosphere of the space.
Townhouse in San Felipe

Casa Vidal - The Only House in Casco Viejo

LocationValueWalkability

4.89 out of 5 average rating, 73 reviews
Superhost
Apartment in Panama City

Cinta Costera Ocean View Suite

LocationValueCleanliness

4.79 out of 5 average rating, 34 reviews
Guest favorite
A modern living area is featured, showcasing a large wall-mounted television surrounded by a lighted panel. Seating is provided by a dark sofa with decorative pillows. A round dining table is visible in the foreground, complemented by four black chairs. Tall windows offer city views.
Apartment in Panama City

Luxury Oceanfront Resort 22nd Floor View, 200°

ValueFamilyKitchen

4.85 out of 5 average rating, 73 reviews

Frequently Asked Questions

  • What are the best places to stay in Panama City?

    Panama City has stays in vibrant neighborhoods like Casco Viejo, known for historic charm, and Punta Pacifica, often suggested for modern towers and city views. Many visitors also enjoy options around El Cangrejo for its mix of cafes and local culture.

  • What are the best things to do in Panama City with kids?

    Explore the Biomuseo’s interactive exhibits, walk the Amador Causeway for city and canal views, or visit parks like Parque Natural Metropolitano to spot wildlife. Many families enjoy boat tours or learning about the canal’s history.

  • What are some of the best things to do in Panama City?

    Wander historic streets in Casco Viejo, explore exhibits at the Panama Canal Museum, and stroll the Cinta Costera waterfront. Food and markets, canal tours, and cultural centers are frequently suggested for first-time visitors.

  • How is the weather in Panama City?

    Panama City has a tropical climate with warm temperatures year-round, often around 75–88°F (24–31°C). Visitors can expect higher humidity, with occasional rain, especially during the wet season.

  • What are the best places to visit in Panama City?

    Casco Viejo’s historic architecture, the Panama Canal, and the Biomuseo are often highlighted for visitors. The Amador Causeway is also suggested for scenic walks and views over the bay.

  • What are some hiking trails in Panama City?

    Parque Natural Metropolitano has trails through tropical forest with city vistas and wildlife. The Sendero El Gaital path and walking routes around Cerro Ancón are also frequently suggested for those who want a nature escape near urban sights.

  • What are some family activities we can do in Panama City?

    Families often enjoy the interactive displays at Biomuseo, relaxing on the Amador Causeway, and wildlife spotting in Parque Natural Metropolitano. Parks with playgrounds and canal boat tours are also popular with kids.

  • What are some of the best day trip ideas from Panama City?

    Day trips from Panama City often include hiking in nearby rainforest reserves, visiting Gamboa for canal views and nature tours, or relaxing on beaches around the Pearl Islands. Guided excursions introduce travelers to indigenous cultural sites as well.

  • Are there any pet friendly accommodations available in Panama City?

    Panama City has pet-friendly stays, especially in neighborhoods like El Cangrejo and San Francisco, where parks and walkable streets make it easy to enjoy the city with your pet. Many hosts welcome dogs and cats with advance notice.

  • What are some local tips for visiting Panama City?

    When exploring Panama City, lightweight clothing helps with humidity, and a reusable water bottle is useful. Street murals around Casco Viejo show local talent, while trying fresh seafood in city markets gives a taste of regional flavors.

  • What is Panama City known for?

    Panama City is known for the Panama Canal, mix of colonial and modern architecture, and vibrant culinary scene. Its waterfront walks and lively festivals celebrate a crossroads of cultures.

  • What are the best hidden gems to explore in Panama City?

    Panama City has tucked-away art galleries in Casco Viejo, quiet gardens at Mi Pueblito, and street food stands in Santa Ana that attract locals. Seek out small museums and indie coffee shops for a neighborhood experience.

  • What are the best foods to try in Panama City?

    Local favorites include sancocho chicken stew, patacones (fried plantains), and ceviche from city markets. Panamanian seafood, fresh tropical fruits, and pastries filled with local flavors are frequently suggested.

  • What should I bring for a trip to Panama City?

    Bring lightweight, breathable clothing for the tropical climate, comfortable walking shoes, and sun protection like hats and sunscreen. A rain jacket and an adapter for electronics are also practical for your stay.

  • What is the nightlife in Panama City like?

    Panama City has a vibrant nightlife scene, with lively rooftop bars, salsa venues, and music lounges in Casco Viejo. Neighborhoods like Calle Uruguay and El Cangrejo are known for dance clubs, craft cocktail spots, and casual pubs. Visitors often explore a mix of local rhythms and international influences after dark.

  • What are the most popular events or festivals in Panama City?

    Carnival is one of the most popular celebrations, filling Panama City with music, parades, and color before Lent. Jazz festivals, local art fairs, and folklore events also draw crowds throughout the year.

  • Are there family friendly vacation rentals in Panama City?

    Panama City has family-friendly vacation rentals, especially in areas near parks and cultural attractions like El Cangrejo, San Francisco, and Casco Viejo. Many hosts provide amenities for children and groups traveling together.

  • When is the best time to visit Panama City?

    The drier season is often recommended for clearer skies and outdoor activities. Many travelers prefer visiting when major cultural events and festivals enliven the city’s atmosphere.

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