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Boutique hotel vacation rentals in Southern United States

Find and book unique boutique hotel rentals on Airbnb

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Popular amenities for Southern United States boutique hotel rentals

Family-friendly boutique hotels rentals

Guest favorite
Hotel room in Fairhope
4.92 out of 5 average rating, 142 reviews

Cool, cozy, contemporary and romantic! Location!

LaurenRating, 5 stars1 month ago
Great, very new and well appointed. Nice access to the bay. Wonderful location. We will definitely be back.
Hotel room in Grand Isle
4.87 out of 5 average rating, 31 reviews

Gulf Front Suite - 2 Bedrooms with Kitchen

EthanRating, 5 stars1 month ago
Place was in a great location with an awesome deck, check in was easy and host was very responsive. Great place to stay in Grand Isle.
Top guest favorite
Hotel room in Newport
4.96 out of 5 average rating, 550 reviews

#5 No Cleaning/Parking Fees! Walk to Games/Music!

SherryRating, 5 stars1 week ago
Had a great stay. Jeff was very attentive. Loved the room.
Guest favorite
Hotel room in Fort Lauderdale
4.8 out of 5 average rating, 1,306 reviews

King Room - Oceanfront Property

ToniRating, 5 stars1 day ago
What a great stay! Matt made checking in super easy and was very helpful. He was clearly dedicated to giving all guests a great stay. Would stay again!
Superhost
Hotel room in Hot Springs National Park
4.9 out of 5 average rating, 210 reviews

Room 10 · Holiday Road Room-Dame Fortune’s Cottage Court

ChelseyRating, 5 stars14 months ago
This place was none the less than spectacular!!! Upon arriving for the Solar Eclipse Andie greeted us outside and gave us some eclipse glasses. She shared local restaurants, gave us a token to remember to eclipse and always made sure to say hi when she saw us on property!! Beautiful location, the restoration of this older property is phenomenal and the price was perfect. Huge thank you for making this trip special and we look forward to coming back and having our wedding party visit next year! Thank you Andie!!
Top guest favorite
Hotel room in Bay St. Louis
4.97 out of 5 average rating, 233 reviews

The Happy Place

AlexanderRating, 5 stars1 week ago
We thoroughly enjoyed our weekend in Bay St. Louis and our stay at this lovely place. There is a magical quality to the property, with its lush garden complete with a goldfish pond and the cats and dogs. The place was comfortable (for two people) and the location is great. It's an easy walk to the heart of the town and the beach.
Top guest favorite
Hotel room in Lauderdale-by-the-Sea
4.97 out of 5 average rating, 105 reviews

The Little Inn with a Big ❤️

DouglasRating, 5 stars1 week ago
This place is wonderful! The property manager, Cindy was super attentive, and made our stay memorable! The property is spotless, close to everything, and within walking distance to the beach, and downtown area!
Top guest favorite
Hotel room in Apalachicola
4.97 out of 5 average rating, 112 reviews

The Pearl Suite at The Riverwood Suites

LaurieRating, 5 stars1 month ago
We had a lovely stay at The Pearl Suite. It was just perfect! Charming decor, comfortable furniture, plenty of space...it had it all. The location was very good, walked everywhere in downtown Apalachicola. Very much enjoyed our stay!

Boutique hotels rentals with a patio

Guest favorite
Hotel room in Austin
4.94 out of 5 average rating, 251 reviews

New High Rise 2 Bedroom Condo Rainey District

KatherineRating, 5 stars2 weeks ago
We have stayed with Jason several times and are never disappointed! The place is in a great location, has all the amenities you need and he is very responsive and accommodating. The unit is clean and comfortable, I highly recommend booking, you will not be disappointed!
Top guest favorite
Hotel room in Corrales
4.98 out of 5 average rating, 148 reviews

Victorian Carriage House Studio

SallyRating, 5 stars1 week ago
Jennifer’s home is beautiful, Victorian charm and ambiance. The room is spacious and beautifully decorated with a large en suite bathroom. We felt very pampered. The location was easy to find and even though most restaurants in the village were closed because it was a Monday, there are other restaurants and shopping a couple of miles away. I would highly recommend the room at Jennifer’s.
Guest favorite
Hotel room in Albuquerque
4.95 out of 5 average rating, 116 reviews

The Kings Parlour @ The Raven ABQ

JessicaRating, 5 stars3 months ago
Always love to stay here, it's easily walkable to downtown but far enough away to be quiet and peaceful overnight. The bedroom is beautiful and spacious, and the other shared areas easy access for kitchenette/sitting and dining areas. Love the local art decor!
Guest favorite
Hotel room in Bandera
4.87 out of 5 average rating, 124 reviews

Rustic 3 bed cabin with upscale hotel amenities

ElizabethRating, 5 stars1 month ago
We enjoyed our stay while here! The owner was friendly and responsive. We enjoyed the ducks that came and visited us.
Superhost
Hotel room in St. Augustine
4.81 out of 5 average rating, 190 reviews

Downtown Boutique Bed & Bath w Balcony, Unit 1

EliannaRating, 5 stars2 weeks ago
monique and jared were hands down the best airbnb hosts i’ve ever had! they were extremely helpful and responsive and checked in when we were on the porch. additionally, when my friend got hurt they were extremely helpful and kind when it came to finding an urgent care and getting her to the car. overall, i would absolutely stay here again and would highly recommend this place to others! beautiful area, very close to restaurants and shops, and overall very peaceful.
Top guest favorite
Hotel room in Hollywood
4.98 out of 5 average rating, 127 reviews

Boutique hotel with patio steps from the beach2

AlexanderRating, 5 stars4 weeks ago
excellent value and location, location, location. Very cozy and chill. Host was on top of everything and communicated well.
Superhost
Hotel room in New Orleans
4.83 out of 5 average rating, 100 reviews

Carnival Royalty French Quarter Guest House

LauraRating, 5 stars5 days ago
Would definitely stay here again.
Guest favorite
Hotel room in Miami
4.83 out of 5 average rating, 270 reviews

Spacious & fully furnished, 2 queen beds & bath

ChristopherRating, 5 stars3 weeks ago
the room looked huge in the photos, and it was even bigger in person

Monthly boutique hotels rentals

Guest favorite
Hotel room in Monterrey
4.82 out of 5 average rating, 17 reviews

Hostal del Barrio/Room #09 single bed

MarlenRating, 5 stars3 weeks ago
This place it’s by Barrio Antiguo. Great area easy check in .. Always polite and the place is clean. I really like to stay here . I will come back for sure !!
Hotel room in Chihuahua
4.67 out of 5 average rating, 257 reviews

La Decima (clean rate / no hidden fees)

Víctor FranciscoRating, 5 stars34 months ago
The place is superbly located, a pretty good price and the breakfast of 10. Totally would come back. Very good quality/price ratio
Guest favorite
Hotel room in Kenbridge
4.79 out of 5 average rating, 48 reviews

Adorable Efficiency Suite-2- Heart of Kenbridge!

AaronRating, 5 stars2 months ago
Booked for one of our employees who was assisting a near by medical facility. Vanessa was responsive and took care of us so we can take care of others. Much appreciated.
Guest favorite
Hotel room in Chihuahua
4.89 out of 5 average rating, 127 reviews

#2 Coronado4veinte downtown area Chepe boutique hotel

Jesus OctavioRating, 5 stars3 days ago
It was very nice to stay with Rossina. He had a nice touch for us, which is much appreciated. We will definitely be back
Superhost
Hotel room in Branson
4.7 out of 5 average rating, 98 reviews

Cozy Boutique #17 by Silver Dollar City Economy

MariaRating, 5 stars1 week ago
It was very easy to communicate with Emily and any questions were answered in a timely manner!
Hotel room in Delicias
4.73 out of 5 average rating, 22 reviews

4. Charming boutique hotel with patio and garden. Centrally located, private room with air conditioning.

IsaacRating, 5 stars12 months ago
Easy access, good location, nice
Hotel room in Kremmling
4.56 out of 5 average rating, 27 reviews

Two Queen Economy Room - Shared Restrooms

JohnRating, 5 stars9 months ago
Historic hotel in a rad town in the moutains. Historic Hotel like a boarding house back in the day. Many rooms have a shared bathroom down the hall. Some rooms have a private bath. Awesome old wood floors squeak and creak fairly loudly. I dug it and thought of it as the floors were talking story of all that's times past. If your sensitive to noise and the funky quirks of an Old time Historic hotel...... maybe stay on the main highway and hit up a holiday inn! If on the otter hand you like character, history, adventure and meeting random travelers in a cool, comfortable and inviting mountain cowboy hotel... Then this is a good spot to hang your hat and rest your head to be ready for the next days Adventure!
Hotel room in Monterrey
4.74 out of 5 average rating, 19 reviews

01 Downtown Hotel Boutique!

RobertoRating, 5 stars1 month ago
Nice place, in an area for walking in the Old Quarter. Just note that there's not much parking, in case you come by car.

Destinations to explore