
Vacation rentals in Saint Charles
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Saint Charles
Guests agree: these stays are highly rated for location, cleanliness, and more.

The Hen House
The wonderfully remodeled home based on 55 acres overlooking mature trees and a large pond. The house has 3 bedrooms and 1 1/2 baths. Laundry is available to use as well. Kitchen is fully stocked for your cooking enjoyment and a gas grill is offered as well to use. This house is perfect for families, small groups, or business trips. Situated just 20 minutes from Des Moines airport, and 25 minutes from downtown Des Moines, you will be able to experience the quiet and beautiful scenery to enjoy.

Aerie Loft Apartment with view that sleeps 7
This elevated second story apartment has an incredible view of the historic downtown square and courthouse. Bring your group to be in a centralized location near dining/bars , shopping, museums, and a movie theatre. Accommodations for a group of seven is ideal for getaways or special occasions. The unique relief art sculpture of a tree and eagles will captivate you. A full kitchen with all the essentials. 6 beds and spacious 3/4 bath and a second 3/4 bath opened for 5 or more guests.

Charming Waterfront Tiny House & Sauna
The true definition of rest & relaxation, this unique tiny house is situated on a three-acre pond suitable for catch and release fishing, kayaking, or stand up paddle boarding. Bring your gear and leave your worries behind. Built with special touches and details including stained glass windows and intricate woodwork, this tiny home boasts warmth throughout. Wake up to bird songs and coffee with the sunrise. After a day of fun, take a soak in the wood-burning sauna and relax by the campfire.

The Legacy Stone House
The most unique stay in Winterset! Legacy Stone House AirBnB is a historic residence located one mile east of Winterset, Iowa. Built in 1856 during the Settlement Era of Madison County, it is one of nearly 100 stone houses built during that time in the area. Officially named the William Anzi Nichols House, it is listed on the National Register of Historic Places. Convenient centralized location if visiting Madison County’s six covered bridges and two minutes from grocery, gas and dining.

Iconic Iowa - A 1920 Built Country Cabin
This 1920 Log Cabin sits at the beginning of the Madison County covered bridges Scenic Byway and features 2 rural country acres of space and a wonderfully remodeled home with loads of character and style. Situated just 10 minutes south of the West Glen area of West Des Moines and 25 minutes from downtown Des Moines, you'll experience the quiet and beauty of rural Iowa while being close enough for shopping or to go out for a nice dinner or evening show. This is a great getaway.

Windy Pines Suite
Windy Pines offers a spacious bedroom with a comfortable king sized bed and large bathroom. The kitchen and living room are great. This clean, comfortable, & uncluttered space is a home away from home! You will be surrounded by beautiful greenery, in a safe neighborhood with accessible parking. Close to interstate 80 & 35, the Iowa State Fair Grounds, and Downtown Des Moines. WP is attached to our home but with its own separate outside entrance. Please send me any questions.

Friendly Quarters
This charming location is a farmhouse style home built in 1914. Easily found on the main street through town, a one block walk in any given direction will put you at the center of the city. A grocery story, eating establishments, gift shops and community center are conveniently located in the downtown area. Friendly Quarters operates as a non-profit organization to support the missions and ministries of Earlham Friends (Quaker) Church located right next door.

Charming Bungalow in a Great Location!
This 1910 PET FRIENDLY bungalow is full of charm and unique art. Just a couple of blocks to the town square for restaurants and shopping. In the summer you will enjoy the quaint front porch and backyard patio full of colorful flowers nice for outdoor dining. The fenced backyard is perfect for bringing your dog. Small dogs 25 pounds and under require a one time $50 pet fee and dogs larger than that are up for discussion. Close to Buxton Park for scenic walks.

Kim's Kottage on the RRVT, in Minburn, IA.
This home is perfect for the Cycling Enthusiast, a couple, family or small group of friends. This fully furnished cozy 2 bedroom home is sure to please. Located 1 block from the Raccoon River Valley Bike Trail (75 mile paved loop), 15 minutes from I-80 and 30/40 minutes from the State's Capital City of Des Moines, Minburn is the "Small Town with a Big Heart". There are two City Parks, an outdoor historical roller skating rink & 2 Rest/Bars.

Relaxing galaxy bell tent getaway
Come sleep under the stars in this cozy galaxy bell tent. You can enjoy a good nights sleep in the comfortable King bed and stay comfortable with an air conditioner and heater. There is also a fridge for keeping your food fresh. Soak up nature while you hike the trails around Oak Haven Acres, a 32 acre farm in rural Iowa. For your security we have a trail camera at the beginning of the driveway that won’t intrude on your privacy.

Unique Spanish Bungalow!
Come experience a house unlike any other in Des Moines. This unique Spanish-style home has a global personality and centrally located. Walking distance to many amenities and pet friendly! The words most often used by guests are warm, inviting, eclectic, spotless, charming, and peaceful. PLEASE NOTE: Street construction will resume in Spring 2026 near the house. Access to the house and driveway will not be affected.

2 BR fully furnished private condo sleeps 4
2 blocks from courthouse square businesses. High speed internet 250 meg. 2 private parking lots. 30 min from Des Moines. Walking distance to the corner tavern. Gas station across the street. Please note, address is 314. AirBnB doesn't recognize the address and it defaults to 316. Private residence is 314 door in front of the driveway on the North side of the house.
Popular amenities for Saint Charles vacation rentals
Other great vacation rentals in Saint Charles

Quiet Country home, nature & fishing -5min to city

Cozy Country Retreat

Covered Bridge Haven - 3BR House w/ Themed Rooms

Historic Lustron Home near Indianola Square

Cozy Loft South of Pleasantville

Peaceful 2-bedroom home in scenic countryside

Entire farmhouse in the country

Glamping Flower Farm Stay- PepperHarrow
Destinations to explore
- Platteville Vacation rentals
- St. Louis Vacation rentals
- Kansas City Vacation rentals
- Minneapolis Vacation rentals
- Wisconsin River Vacation rentals
- Lake of the Ozarks Vacation rentals
- Omaha Vacation rentals
- Minnesota River Vacation rentals
- Twin Cities Vacation rentals
- Madison Vacation rentals
- Central Illinois Vacation rentals
- Wisconsin Dells Vacation rentals




